Feasibility study of biobanking of faecal tissue for 16S rRNA sequencing and metabolomic studies via the NHS Biorepository and associated blood samples
Different people have different harmless bacteria living in their gut. Recently these have been shown to affect how well a patient responds to cancer treatments such as chemotherapy or immunotherapy, but so far there is little work on how they affect surgical or radiotherapy treatments.
We already collect tumour and bloods samples from patients with their consent and store them for future scientific research. We now want to collect samples, from bowel, prostate, or womb cancer patients, of their faeces to see if the gut bacteria can influence how well they respond to radiotherapy or surgery. We can look at the DNA from the bacteria and also the chemicals that they release that may help the radiotherapy or surgery work better.
Project Leads
- Professor Anne Kiltie School of Medicine, Medical Sciences and Nutrition
- George Ramsay School of Medicine, Medical Sciences and Nutrition
Other Applicants
- Justine Royle
Chairwoman of cancer charity UCAN
- Dr Leslie Samuel School of Medicine, Medical Sciences and Nutrition
- Mahalakshmi Gurumurthy
Consultant Gynaecologist & Gynaecological Oncologist