Personal Chair
- About
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- Email Address
- m.romano@abdn.ac.uk
- Telephone Number
- +44 (0)1224 272507
- Office Address
- Office 337, Institute for Complex Systems and Mathematical Biology, Department of Physics, Meston Building, Old Aberdeen Office 3:47, Institute of Medical Sciences, Foresterhill
- School/Department
- School of Natural and Computing Sciences
- Research
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Research Overview
I am interested in the understanding of fundamental biological processes using theoretical approaches based on nonlinear dynamics and statistical physics and combining them with experimental data. In particular, I am interested in the process of translation or synthesis of proteins, the coupling between transcription and translation, how ribosomes, the molecular machines that manufacture proteins, are synthesised, and its relationship to the cell cycle. I am furthermore interested in the effect of combinatorial stresses in yeast, as well as the effects of different types of stress on the cell cycle.
Funding and Grants
SULSA studentship (modeling of translation)/ SABR grant (Combinatorial Responses In Stress Pathways)/BBSRC grant (Ribosome Traffic Flow on the mRNA as a Regulator of Cellular Protein Production)
- Teaching
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Teaching Responsibilities
Electromagnetism (PX3008, 3rd year Physics) and Introduction to Mathematics and Modelling of Biological Systems (SB5005, MSc in Cell and Molecular Systems Biology)
- Publications
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Page 1 of 8 Results 1 to 10 of 73
What determines sub-diffusive behavior in crowded protein solutions?
Biophysical Journal, vol. 123, no. 2, pp. 134-146Contributions to Journals: ArticlesExpressInHost: A codon tuning tool for the expression of recombinant proteins in host microorganisms
Journal of Open Research Software, vol. 11, no. 2Contributions to Journals: ArticlesTwo-species totally asymmetric simple exclusion process model: From a simple description to intermittency and traveling traffic jams
Physical Review E, vol. 105, no. 3, 034117Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1103/PhysRevE.105.034117
The molecular aetiology of tRNA synthetase depletion: induction of a GCN4 amino acid starvation response despite homeostatic maintenance of charged tRNA levels
Nucleic Acids Research, vol. 48, no. 6, pp. 3071-3088Contributions to Journals: ArticlesTranslational control of gene expression via interacting feedback loops
Physical Review. E, Statistical, Nonlinear and Soft Matter Physics, vol. 100, no. 5, 050402(R)Contributions to Journals: ArticlesDefinition Of The Minimal Contents For The Molecular Simulation Of The Yeast Cytoplasm
Frontiers in Molecular Biosciences, vol. 6, 97Contributions to Journals: Articles- [ONLINE] https://www.frontiersin.org/articles/10.3389/fmolb.2019.00097/full#supplementary-material
- [ONLINE] DOI: https://doi.org/10.3389/fmolb.2019.00097
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13056/1/fmolb_Kompella_et_al_Definition_of_minimal_contents_VoR.pdf
- [ONLINE] View publication in Scopus
Power series solution of the inhomogeneous exclusion process
Physical Review. E, Statistical, Nonlinear and Soft Matter Physics, vol. 97, no. 5, 052139Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1103/PhysRevE.97.052139
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11267/1/PhysRevE.97.052139.pdf
Deciphering mRNA Sequence Determinants of Protein Production Rate
Physical Review Letters, vol. 120, no. 12, 128101Contributions to Journals: ArticlesNovel mRNA-specific effects of ribosome drop-off on translation rate and polysome profile
PLoS Computational Biology , vol. 13, no. 5, e1005555Contributions to Journals: ArticlesSynthetic biology routes to bio-artificial intelligence
Essays in Biochemistry, vol. 60, no. 4, pp. 381-391Contributions to Journals: Articles