PhD-students currently working in this area:
Identification and quantification of sulphur compounds can be difficult due to the sheer number of sulphur compounds normally present in biological samples.
There are two major research projects actively pursued at the moment. One project is researching small sulphur containing molecules in alliums (garlic, onion….) and deducing their metabolic pathways.
Included in this project is the quantification of phosphorylated peptides after enrichment to determine the phosphorylation status of proteins.
Protein phosphorylation is one of the post-translational modifications of proteins, which influences their metabolic fate and activity. Effective peptide enrichment for the determination of phosphorylation is essential, since at any given time only a small part of the proteome is phosphorylated.
The project homepage can be found at: http://www.ptb.de/emrp/remind.html