Senior Lecturer
- About
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Biography
SHARON HANLEY is a cancer epidemiologist in the Department of Academic Primary Care in the Institute of Applied Health Sciences at the University of Aberdeen. She ia also a member of Aberdeen Centre for Women’s Health Research. She obtained her PhD in Public Health and Epidemiology from Hokkaido University Graduate School of Medicine in Sapporo, Japan. She also has an MA (Hons) in Modern Languages from the University of St Andrews.
Sharon has an outstanding record of public health leadership in both cervical cancer screening and the human papillomavirus (HPV) vaccination and is passionate about equity in public health outcomes. She sits on several national and international steering groups for cervical cancer control, including the Japan Cancer Society’s working group for HPV Self-sampling, the HPV Prevention and Control Board, the COVID-19 and Cancer Global Modelling Consortium and the World Health Organization reference group on Behavioural and Social Drivers (BeSD) of HPV vaccination.
Sharon strives to get as many girls as possible vaccinated against the HPV and has been invited to speak on the topic of HPV vaccine hesitancy at over 100 national and international meetings. She has also provided consultation on HPV vaccine safety to public health professionals in countries such as Ireland, Denmark and Columbia, who have faced issues similar to Japan regarding HPV vaccine hesitancy.
Her current research focuses on developing and validating a Japanese version of the BeSD tools (surveys, interview and implementation guides) and as well as how cervical screening can best meet the needs of disadvantaged groups who have poorer cervical cancer outcomes in Scotland. She is particularly interested in HPV self-sampling.,
In her free time, she volunteers for Sapporo English Medical Interpreters group, where she uses her native level proficiency in Japanese to help non-Japanese citizens access local cervical cancer screening and childhood immunization programmes.
External Memberships
PROFESSIONAL AFFILIATIONS
2020- present International Partnership for Resilience in Cancer Systems (I-PARCS)
2015- present Board Member: International HPV Prevention and Control Board
2013- present Executive Board Member: Cancer Support Hokkaido
2009- present Executive Board Member: People’s Campaign Against Female Cancers (PCAF)
2009- present Executive Board Member: Professional Women's Coalition for Sexuality and Health
2009- present Advisor and volunteer interpreter and translator: Sapporo English Medical Interpreters (SEMI)
ACADEMIC AFFILIATIONS
2021-2022 Co-Chair Scientific Program Committee (Public Health), International Papillomavirus Society
2019- present Scientific Programme Committee, European Research Organisation in Genital Infection and Neoplasia
2009-present European Research Organisation in Genital Infection and Neoplasia
2009- present International Papillomavirus Society
2009- present Japan Epidemiological Association
2009- present Japanese Society of Public Health
2009- present Japan Society for Cancer Prevention
2009- present Japan Cancer Society
2009- present Japan Society of Adolescent Health
2009- present Japan Society of Obstetrics and Gynaecology
2009- present Japan Society of Gynaecologic Cancer Screening
2009- present International Epidemiological Association
2009- present Asia-Oceania Research Organisation in Genital Infection and Neoplasia
Prizes and Awards
2021: Excellent Original Paper Award
Impact of HPV vaccine hesitancy on cervical cancer in Japan: a modelling Study Lancet Public Health, 2020 Apr;5(4):e223-e234 Hokkaido University Graduate School of Medicine
2020: Excellent Teacher Award
Hokkaido University Graduate School of Medicine
2020: Daiwa Award (with the University of Hokkaido)
Japan UK collaboration using 21st century technology to improve access to and participation in cervical cancer screening programs, Anglo Japanese Daiwa Foundation, London, UK
2019: Butterfield Award (with the University of Edinburgh)
HPV based interventions for the prevention of cervical cancer, UK Sasakawa Foundation, London, UK
2016: Women in Global Science (WINGS) Award
Hokkaido University, Sapporo, Japan
2015: International Travel Award (Excellent Oral Presentation)
The Japanese HPV Vaccine Tragedy, 41st Annual Meeting of the Korean Cancer Association with International Cancer Conference, Seoul, South Korea
2015: Good Poster Award
The role of HPV self-sampling to increase cervical screening uptake, 67th Annual Congress of the Japan Society of Obstetrics and Gynaecology, Yokohama, Japan
2014: Best Oral Presentation,
Attitudes towards HPV Self-Sampling and Physician Led Cervical Screening in Japanese Women, AOGIN 2014, Peking, China
2012; Best Original Paper
Acceptance of and attitudes towards human papillomavirus vaccination in Japanese mothers of adolescent girls, Japanese Foundation for Sexual Health Medicine Tokyo, Japan
- Research
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Funding and Grants
2020-2022 Japan Society for the Promotion of Science (JSPS): Implementation and evaluation of a nurse-led cervical screening programme: Increasing screening coverage. Co-investigator, grant holder Professor Rika Kudo, Toyama Prefectural University of Nursing, 17,680,000 yen (Grant No:19H01390)
2019-2021 Japan Society for the Promotion of Science (JSPS): Reviewing maternity care policies for achieving MDG5 in Asia: Focusing on de-medicalization and positive birth experience. Co-investigator, grant holder Professor Etsuko Matsuoka, Nara Women’s University, 15,600,000 yen (Grant No:20H04002)
2018-2020 Japan Society for the Promotion of Science (JSPS): Development and validation of a training programme for Japanese midwives to perform cervical screening. Co-investigator, grant holder Professor Tokiko Oishi, Takasaki University of Health and Welfare, 4,420,000 yen (Grant No:18K10481)
2017-2019 Japan Society for the Promotion of Science (JSPS): Increasing screening uptake: Training Japanese nurses to perform cervical screening. Co-investigator, grant holder Professor Rika Kudo, Toyama Prefectural University of Nursing, 6,240,000 yen (Grant No:17K19851)
2016-2018 Japan Society for the Promotion of Science (JSPS): A randomized-control trial assessing the impact of HPV self-sampling on cervical screening uptake rates in women 20- 29yrs: A comparative evaluation of two novel cervico-vaginal self-sampling devices. Grant holder and Principal Investigator, 16,380,000 yen (Grant No: 16H05253)
2016-2018 Japan Society for the Promotion of Science (JSPS): Attitudes Towards and Acceptance of HPV Vaccine in Japanese Mothers of Adolescents living in the UK and Australia. Grant holder and Principal Investigator, 3,640,000 yen (Grant No:16K15367)
2015-2016 Japan Society for the Promotion of Science (JSPS): HPV self-sampling: A novel method to increase screening uptake. Co-investigator, grant holder Professor Noriaki Sakuragi, Hokkaido University, 2,900,000 yen (Grant No:15K15230)
2014-2016 Japan Society for the Promotion of Science (JSPS): HPV Self-sampling: An innovative system to investigate HPV vaccine efficacy and increase cervical screening in young women. Grant holder and Principal Investigator, 3,770,000 yen (Grant No:26670323)
2013-2015 Japan Society for the Promotion of Science (JSPS): Development of educational materials for school children to promote awareness and correct understanding of cancer. Grant holder and Principal Investigator, 18,850,000 yen (Grant no:25282208)
2010-2012 Japan Society for the Promotion of Science (JSPS): Attitudes towards and acceptance of HPV vaccine in mothers of adolescent daughters: Maximizing the impact of HPV vaccination in Japan. Grant holder and Principal Investigator, 4,550,000 yen (Grant no:22590600)
Non JSPS grants
2020-2022 Anglo Japanese Daiwa Foundation: Japan UK collaboration using 21st century technology to improve access to and participation in cervical cancer screening programs. Grant holder and Principal investigator with Professor Maggie Cruickshank, University of Aberdeen. £2,500
2019-2021 National Cancer Institute (Japan): Individually Tailored Strategies for the Prevention of Cervical and Lung Cancer Co-investigator, grant holder, Dr Etsuko Saito, National Cancer Institute, 10,000,000 yen (Grant No: PJ7L210005)
2019-2022 Sasakawa Foundation: HPV based interventions for the prevention of cervical cancer. Grant holder and Principal investigator with Dr Kate Cuschieri, University of Edinburgh. £10,800
2010 Ito Foundation Travel Grant, EUROGIN 2010, 300,000 yen
- Publications
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Correction: Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer.
Oncogene, vol. 38, no. 20, pp. 5257-5268Contributions to Journals: ArticlesExploring lncRNA-mediated regulatory networks in endometrial cancer cells and the tumor microenvironment: Advances and challenges
Cancers, vol. 11, no. 2, 234Contributions to Journals: Review articlesBivalent Human Papillomavirus Vaccine Effectiveness in a Japanese Population: High Vaccine-Type-Specific Effectiveness and Evidence of Cross-Protection
The journal of infectious diseases, vol. 219, no. 3, pp. 382-390Contributions to Journals: ArticlesDifferential misclassification between self-reported status and official HPV vaccination records in Japan: Implications for evaluating vaccine safety and effectiveness.
Papillomavirus Res, vol. 6, pp. 6-10Contributions to Journals: ArticlesLong Non-coding RNA NEAT1: A Novel Target for Diagnosis and Therapy in Human Tumors.
Frontiers in Genetics, vol. 9, 471Contributions to Journals: ArticlesControl of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer.
Oncogene, vol. 37, no. 39, pp. 5257-5268Contributions to Journals: ArticlesTumor-Intrinsic PD-L1 Signaling in Cancer Initiation, Development and Treatment: Beyond Immune Evasion.
Frontiers in Oncology, vol. 8, 386Contributions to Journals: ArticlesTime trends in suicide rates by domestic gas or car exhaust gas inhalation in Japan, 1968-1994.: Epidemiology and psychiatric sciences
Epidemiol Psychiatr Sci, vol. 28, no. 6, pp. 644-654Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S2045796018000410
Job Stress Factors Affect Workplace Resignation and Burnout among Japanese Rural Physicians.
The Tohoku journal of experimental medicine, vol. 245, no. 3, pp. 167-177Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1620/tjem.245.167
B7H3 As a Promoter of Metastasis and Promising Therapeutic Target
Frontiers in Oncology, vol. 8, 264Contributions to Journals: ArticlesComparison of human papillomavirus genotyping and cytology triage, COMPACT Study: Design, methods and baseline results in 14 642 women.
Cancer Science, vol. 109, no. 6, pp. 2003-2012Contributions to Journals: ArticlesmiR-34a, miR-424 and miR-513 inhibit MMSET expression to repress endometrial cancer cell invasion and sphere formation.
Oncotarget, vol. 9, no. 33, pp. 23253-23263Contributions to Journals: ArticlesRelationships between road-distance to primary care facilities and ischemic heart disease and stroke mortality in Hokkaido, Japan: A Bayesian hierarchical approach to ecological count data.
Journal of general and family medicine, vol. 19, no. 1, pp. 4-8Contributions to Journals: ArticlesOvercoming barriers in HPV vaccination and screening programs
Papillomavirus Res, vol. 4, pp. 45-53Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.pvr.2017.07.001
Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation.
J Exp Clin Cancer Res, vol. 36, no. 1, 150Contributions to Journals: ArticlesSocial support and its interrelationships with demand-control model factors on presenteeism and absenteeism in Japanese civil servants.
International Archives of Occupational and Environmental Health , vol. 90, no. 6, pp. 539-553Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00420-017-1218-y
EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis.
Oncotarget, vol. 8, no. 8, pp. 13509-13520Contributions to Journals: ArticlesSuppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124
Scientific Reports, vol. 6, 35480Contributions to Journals: ArticlesMiR-137 and miR-34a directly target Snail and inhibit EMT, invasion and sphere-forming ability of ovarian cancer cells.
Journal of Experimental and Clinical Cancer Research, vol. 35, no. 1, 132Contributions to Journals: ArticlesChallenges in breast and cervical cancer control in Japan.
The Lancet Oncology, vol. 17, no. 9, pp. e372Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/S1470-2045(16)30411-9
HPV self-sampling in Japanese women: A feasibility study in a population with limited experience of tampon use
Journal of Medical Screening, vol. 23, no. 3, pp. 164-170Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1177/0969141315625702
Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression.
Oncotarget, vol. 7, no. 15, pp. 20260-20270Contributions to Journals: ArticlesTime trends in method-specific suicide rates in Japan, 1990-2011
Epidemiology and Psychiatric Sciences, vol. 25, no. 1, pp. 58-68Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S2045796014000675
A Pilot Study Investigating Acceptability of HPV Self-Sampling in Japanese Women of Reproductive Age
International Journal of Epidemiology, vol. 44, no. Supplement 1, pp. i53Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1093/ije/dyv097.201
Epidemic of Charcoal Burning Suicide in Japan.
International Journal of Epidemiology, vol. 44, no. Supplement 1, pp. i167Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1093/ije/dyv096.227
