![Professor Marion Campbell Professor Marion Campbell](/img/200x200/staffpages/uploads/sme098/avatar/ZLjE8vL4N76auwU15zJUYuOVjpMZZqvIXx1cI3SL.jpeg)
BSc (Hons), MSc, PhD, CStat, FSS, FFPH, FSCT, FRSE, FMedSci
Chair in HSRU
- About
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- Email Address
- m.k.campbell@abdn.ac.uk
- Telephone Number
- +44 (0)1224 273161
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Professor Marion Campbell is Professor of Health Services Research at the University of Aberdeen. She is also co-Director of the RCSEng Aberdeen Surgical Trials Centre. Marion is a medical statistician by training, a clinical trialist and methodologist. Her main research interests are in the design, conduct and analysis of clinical trials especially complex trial design and the design and conduct of surgical and device trials. She has published widely on clinical trials methodology including on cluster randomised trials, design of trials of surgical interventions, pragmatic trials and trials reporting. She has served on many national and international funding agencies and committees and is an elected Fellow of the Academy of Medical Sciences, the Royal Society of Edinburgh, the Faculty of Public Health, and the International Society for Clinical Trials and is a previous NIHR senior investigator.
Previously Marion was Vice-Principal (Research) for the University of Aberdeen. In this role, she had primary responsibility for promoting the University's research ambitions, ensuring effective delivery of the University's strategic objectives for research. and for enabling a research context for academic colleagues to deliver world-leading, impactful research. She also led on the establishment of interdisciplinary research across the institution. Prior to this, Marion was Dean of Research for Life Sciences and Medicine following ten years as Director of the Scottish government core-funded Health Services Research Unit.
Marion graduated with an honours degree in Statistics from the University of Aberdeen and subsequently gained an MSc in Statistics and PhD in Public Health. Following early career appointments within the National Health Service in the fields of Operational Research and Statistics of Medical Audit, she joined the University of Aberdeen in 1993.
External Memberships
Chair. MRC Better Methods Better Research Panel
Member of REF2021 UoA2 sub-panel
- Research
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Research Overview
Marion’s main research interests are in the design, conduct and analysis of clinical trials especially complex trial design and the design and conduct of surgical and device trials. She has also published widely on clinical trials methodology including on cluster randomised trials, design of trials of non-pharmacological interventions, pragmatic trials and trials reporting.
Some examples of current and recent research include:
REINFORCE: The NIHR-funded REINFORCE study aims to evaluation the introduction and scale up of robot-assisted surgery across the NHS. Further information is available at: https://www.abdn.ac.uk/hsru/what-we-do/research/projects/reinforce-291
UK-REBOA: The NIHR-funded UK-REBOA trial aims to establish the clinical and cost-effectiveness of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA), in addition to standard major trauma centre treatment, for the treatment of patients with life-threatening torso haemorrhage. The trial is currently live across major trauma centres in England. Further information is available on the trial website: https://w3.abdn.ac.uk/hsru/REBOA/Public/Public/index.cshtml
TOPKAT: The NIHR-funded TOPKAT trial is investigating the clinical and cost effectiveness of partial (PKR) vs total (THR) knee replacements. The trial recruited 528 patients from across the UK. Five year results have been published in the Lancet (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31281-4/fulltext) and showed that PKR has similar, if not a slightly better clinical outcome than TKR. More importantly, the economic benefit of using PKR is substantial. Patients are now being followed up to 10 years.
CLASS: The NIHR-funded CLASS trial is assessing the clinical and cost-effectiveness of three treatment modalities for the treatment of varicose veins: a) foam; b) EVLA with subsequent foam to varicosities when required; and c) surgery. A total of 798 adult patients were recruited into the trial and randomised to one of the treatment options. Six weeks results have been published in the NEJM (http://www.nejm.org/doi/full/10.1056/NEJMoa1400781). Five year follow-up is now complete.
KAT: The NIHR-funded KAT trial, explores different knee replacement surgery options (the effects of patellar resurfacing, mobile bearings and metal backing were investigated). A total of 116 surgeons in 34 UK centres participated and 2352 participants were randomised. Ten year outcomes were previously published (https://www.journalslibrary.nihr.ac.uk/hta/hta18190/#/abstract); long term follow up to 20 years is underway.
Research Areas
Applied Health Sciences
Research Specialisms
- Healthcare Science
- Medical Statistics
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Publications
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Comparison of CAPD delivery systems: Y-set/modified Y-set vs. standard spike
Cochrane Database of Systematic Reviews, no. 2Contributions to Journals: ArticlesCost-utility analysis of open versus laparoscopic groin hernia repair: results from a multicentre randomized clinical trial
British Journal of Surgery, vol. 88, no. 5, pp. 653-661Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1046/j.1365-2168.2001.01768.x
Do the Y-set and double-bag systems reduce the incidence of CAPD peritonitis?: A systematic review of randomized controlled trials
Nephrology Dialysis Transplantation, vol. 16, no. 2, pp. 341-347Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ndt/16.2.341
Extending the CONSORT statement to cluster randomised trials: for discussion
Statistics in Medicine, vol. 20, pp. 489-496Contributions to Journals: ArticlesThe prevalence of prophylaxis for deep vein thrombosis in acute hospital trusts
International Journal for Quality in Health Care, vol. 13, no. 4, pp. 309-316Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/intqhc/13.4.309
Evidence-based medicine in nephrology: identifying and critically appraising the literature
Nephrology Dialysis Transplantation, vol. 15, no. 12, pp. 1950-1955Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ndt/15.12.1950
A recruitment strategy for cluster randomized trials in secondary care settings
Journal of Evaluation in Clinical Practice, vol. 6, pp. 185-192Contributions to Journals: ArticlesAnalysis of cluster randomized trials in primary care: a practical approach
Family Practice, vol. 17, pp. 192-196Contributions to Journals: ArticlesDietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health?
The American Journal of Clinical Nutrition, vol. 71, pp. 142-151Contributions to Journals: ArticlesEvaluation of clinical guidelines for the management of end-stage renal disease in Europe: the EU BIOMED 1 Study
Nephrology Dialysis Transplantation, vol. 15, pp. 1394-1398Contributions to Journals: ArticlesEvidence-based medicine and health economics: A case study of end stage renal disease
Health Economics, vol. 9, pp. 337-351Contributions to Journals: ArticlesExperimental and quasi-experimental designs for evaluating guideline implementation strategies
Family Practice, vol. 17Contributions to Journals: ArticlesDeveloping consumer led maternity services: A survey of women’s views in a local health care setting
Journal of Health Expectations, vol. 2, no. 3, pp. 195-207Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1046/j.1369-6513.1999.00059.x
Neonatal examination and screening trial (NEST): a randomised, controlled, switchback trial of alternative policies for low risk infants
British Medical Journal, vol. 318, no. 7184, pp. 627-631Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.318.7184.627
Linking Community Health Index and Scottish Morbidity Records for neonates: the Grampian experience.
Health Bulletin, vol. 57, no. 1, pp. 70-75Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Bootstrapping: estimating confidence intervals for cost-effectiveness ratios
QJM, vol. 92, no. 3, pp. 177-182Contributions to Journals: Editorials- [ONLINE] DOI: https://doi.org/10.1093/qjmed/92.3.177
Laparoscopic versus open repair of groin hernia: a randomised comparison
The Lancet, vol. 354, pp. 185-190Contributions to Journals: ArticlesEffectiveness and efficiency of methods of dialysis therapy for end-stage renal disease: a review
Health Technology Assessment, vol. 2, no. 5Contributions to Journals: Articles- [ONLINE] http://www.hta.ac.uk/project/924.asp
- [ONLINE] DOI: https://doi.org/10.3310/hta2050
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2079/1/MacLeod%25201998.pdf
Comparing outcomes in renal replacement therapy: how should we correct for case mix?
American Journal of Kidney Diseases, vol. 31, no. 3, pp. 473-8Contributions to Journals: ArticlesDirect disclosure of bone density results to patients: Effect on knowledge of osteoporosis risk and anxiety level
Osteoporosis International, vol. 8, pp. 584-590Contributions to Journals: ArticlesRandomized trial of osteoporosis screening: Use of hormone replacement therapy and quality-of-life results
Archives of Internal Medicine, vol. 157, no. 18, pp. 2121-2125Contributions to Journals: Articles- [ONLINE] View publication in Scopus
- [ONLINE] JAMA Network
Alcohol consumption and age of maternal menopause are associated with menopause onset
Maturitas, vol. 26, no. 1, pp. 21-25Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0378-5122(96)01075-4
- [ONLINE] View publication in Scopus
Health Check ups in General Practice: A patient perspective.
Health Bulletin, vol. 54, pp. 241-247Contributions to Journals: ArticlesPrediction of perimenopausal fractures by bone mineral density and other risk factors
Journal of Bone and Mineral Research, vol. 11, no. 2, pp. 293-297Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Survival on renal replacement therapy in Europe: is there a 'centre effect'?
Nephrology Dialysis Transplantation, vol. 11, no. 2, pp. 300-7Contributions to Journals: ArticlesComplementary therapies in a local healthcare setting. Part1: Is there real public demand?
Complimentary Therapies in Medicine, vol. 4, pp. 39-42Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0965-2299(96)80054-9