![Professor Graeme MacLennan Professor Graeme MacLennan](/img/200x200/staffpages/uploads/sme312/Graeme_McLennan_002.jpg)
Director (CHaRT)
- About
-
- Email Address
- g.maclennan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438147
- Office Address
Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
Qualifications
- BSc Mathematics1997 - University of Aberdeen
- MSc Applied Statistics2004 - Sheffield Hallam University
- Research
-
Research Overview
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
Current Research
A complete list of the CHaRT RCT portolio is available by clicking here
- Teaching
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Teaching Responsibilities
I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.
- Publications
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Page 5 of 5 Results 201 to 239 of 239
Randomized trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone
Journal of Bone and Mineral Research, vol. 25, no. 1, pp. 20-31Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1359/jbmr.090709
Pragmatic multi-centre randomised trial of (1) routine postoperative ICU care and/or (2) pre-operative fluid loading in high-risk surgical patients undergoing major elective and urgent surgery
Edinburgh, United Kingdom: Chief Scientist Office. 7 pagesBooks and Reports: Commissioned ReportsSurveillance following breast cancer: is it cost-effective?
Breast Cancer Research, vol. 12, no. Suppl. 3, pp. 5-6Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/bcr2658
Development and exploratory cluster-randomised opportunistic trial of a theory-based intervention to enhance physical activity among adolescents
Psychology & Health, vol. 24, no. 7, pp. 805-822Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1080/08870440802040707
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/754/1/Araujo-Soares%25202009.pdf
Vitamin D supplementation and type 2 diabetes: a substudy of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438)
Age and Ageing, vol. 38, no. 5, pp. 606-609Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ageing/afp109
Uric acid levels and outcome from coronary artery bypass grafting
Journal of Thoracic and Cardiovascular Surgery, vol. 138, no. 1, pp. 200-205Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jtcvs.2008.12.052
- [ONLINE] View publication in Scopus
Progesterone for the prevention of preterm birth in twin pregnancy (STOPPIT): a randomised, double-blind, placebo-controlled study and meta-analysis
The Lancet, vol. 373, no. 9680, pp. 2034-2040Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(09)60947-8
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2644/1/Norman_2009.pdf
Meaning behind measurement: self-comparisons affect responses to health-related quality of life questionnaires
Quality of Life Research, vol. 18, no. 2, pp. 221-230Contributions to Journals: Articles- [ONLINE] http://aura.abdn.ac.uk/handle/2164/306
- [ONLINE] DOI: https://doi.org/10.1007/s11136-008-9435-1
The Knee Arthroplasty Trial (KAT): design features, baseline characteristics, and two-year functional outcomes after alternative approaches to knee replacement
The Journal of Bone & Joint Surgery. American Volume, vol. 91, no. 1, pp. 134-141Contributions to Journals: Articles- [ONLINE] http://aura.abdn.ac.uk/handle/2164/272
- [ONLINE] DOI: https://doi.org/10.2106/JBJS.G.01074
Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement
Health Technology Assessment, vol. 12, no. 35, pp. 1-168Contributions to Journals: Literature Reviews- [ONLINE] http://hdl.handle.net/2164/266
- [ONLINE] DOI: https://doi.org/10.3310/hta12350
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2312/1/Lourenco_2008.pdf
Minimally invasive treatments for benign prostatic enlargement: systematic review of randomised controlled trials
British Medical Journal, vol. 337, a1662Contributions to Journals: Articles- [ONLINE] http://hdl.handle.net/2164/262
- [ONLINE] DOI: https://doi.org/10.1136/bmj.a1662
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2313/1/Lourenco_2008.pdf
A review of RCTs in four medical journals to assess the use of imputation to overcome missing data in quality of life outcomes
Trials, vol. 9, 51Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1745-6215-9-51
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/1537/1/Trials%25202008.pdf
Alternative approaches to endoscopic ablation for benign enlargement of the prostate: systematic review of randomised controlled trials
British Medical Journal, vol. 337Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.39575.517674.BE
Protocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of bone): a questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventive treatment if they were available
BMC Health Services Research, vol. 8, no. 116, pp. 116Contributions to Journals: Articles- [ONLINE] http://aura.abdn.ac.uk/handle/2164/247
- [ONLINE] DOI: https://doi.org/10.1186/1472-6963-8-116
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2653/1/Langston_2008.pdf
The accuracy of accredited glaucoma optometrists in the diagnosis and treatment recommendation for glaucoma
British Journal of Ophthalmology, vol. 91, no. 12, pp. 1639-1643Contributions to Journals: Articles- [ONLINE] http://bjo.bmj.com/content/91/12/1639
- [ONLINE] DOI: https://doi.org/10.1136/bjo.2007.119628
Vitamin D supplementation to prevent infections: a sub-study of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438)
Age and Ageing, vol. 36, no. 5, pp. 574-577Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1093/ageing/afm091
Applying psychological theories to evidence-based clinical practice: Identifying factors predictive of managing upper respiratory tract infections without antibiotics
Implementation Science, vol. 2, no. 26Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1748-5908-2-26
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/2388/1/Grimshaw_2011.pdf
The effects of mandatory prescribing of thiazides for newly treated, uncomplicated hypertension: interrupted time-series analysis
PLoS Medicine, vol. 4, no. 7, e232Contributions to Journals: ArticlesIs annual surveillance of all treated hypothyroid patients necessary?
BMC Endocrine Disorders, vol. 7, 4Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1472-6823-7-4
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3692/1/Is_annual.pdf
Systematic review of economic evaluations and cost analyses of guideline implementation strategies
European Journal of Health Economics, vol. 8, no. 2, pp. 111-121Contributions to Journals: Articles- [ONLINE] http://aura.abdn.ac.uk/handle/2164/152
- [ONLINE] DOI: https://doi.org/10.1007/s10198-007-0043-8
Topical antimicrobials in combination with admission screening and barrier precautions to control endemic methicillin-resistant Staphylococcus aureus in an Intensive Care Unit
International Journal of Antimicrobial Agents, vol. 29, no. 5, pp. 536-543Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ijantimicag.2006.12.019
Is the involvement of opinion leaders in the implementation of research findings a feasible strategy?
Implementation Science, vol. 1, no. 1, 3Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/1748-5908-1-3
- [ONLINE] View publication in Scopus
Applying psychological theory to evidence-based clinical practice: identifying factors predictive of taking intra-oral radiographs
Social Science & Medicine, vol. 63, no. 7, pp. 1889-1899Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.socscimed.2006.04.005
Accuracy of weight and height estimation in an intensive care unit: Implications for clinical practice and research
Critical Care Medicine, vol. 34, no. 8, pp. 2153-2157Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/01.CCM.0000229145.04482.93
Which surgical decisions should patients participate in and how?: Reflections on women's recollections of discussions about variants of hysterectomy
Social Science & Medicine, vol. 62, no. 2, pp. 499-509Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.socscimed.2005.06.027
- [ONLINE] View publication in Scopus
Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement (BPE)
Unknown PublisherBooks and Reports: Commissioned ReportsMethods of hysterectomy: should women have a say?
British Medical Journal, vol. 331, pp. 351-352Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/bmj.331.7512.351-b
Effectiveness and efficiency of guideline dissemination and implementation strategies
International Journal of Technology Assessment in Health Care, vol. 21, no. 1Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0266462305290190
- [ONLINE] View publication in Scopus
A randomised controlled trial of a tailored, multifaceted strategy to promote implementation of a clinical guideline on induced abortion care
BJOG-An International Journal of Obstetrics and Gynaecology, vol. 111, no. 7, pp. 726-733Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1471-0528.2004.00168.x
Women's perceptions of decision-making about hysterectomy
BJOG-An International Journal of Obstetrics and Gynaecology, vol. 111, no. 2, pp. 133-142Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1046/j.1471-0528.2003.00027.x
Effectiveness and efficiency of guideline dissemination and implementation strategies
Health Technology Assessment, vol. 8, no. 6, pp. 1-352Contributions to Journals: ArticlesEffectiveness of strategies to disseminate and implement clinical guidelines for the management of impacted and unerupted third molars in primary dental care, a cluster randomised controlled trial
British Dental Journal, vol. 197, pp. 691-696Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/sj.bdj.4811858
Guidelines can improve process and outcomes of healthcare
Journal of the Royal College of Physicians of Edinburgh, vol. 34, pp. 76-77Contributions to Journals: ArticlesSample size calculator for cluster randomized trials
Computers in Biology and Medicine, vol. 34, no. 2, pp. 113-125Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0010-4825(03)00039-8
Guideline dissemination and implementation strategies: a systematic review of effectiveness and efficiency
Journal of Epidemiology and Community Health, vol. 57, no. 9 Suppl 1Contributions to Journals: ArticlesSurvival Data
In: Key topics in clinical research (eds. Smith,F. G.;Smith,J. E.), BIOS, Oxford, pp. 155-163, 8 pagesChapters in Books, Reports and Conference Proceedings: ChaptersPrevalence of honorary and ghost authorship in Cochrane reviews
JAMA, vol. 287, no. 21, pp. 2769-2771Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1001/jama.287.21.2769
Primary care guidelines on consultation practices: the effectiveness of computerized versus paper-based versions. A cluster randomized controlled trial among newly qualified primary care physicians
International Journal of Technology Assessment in Health Care, vol. 18, no. 3, pp. 586-596Contributions to Journals: ArticlesAttributes of clinical recommendations that influence changes in practice following audit and feedback
Journal of Clinical Epidemiology, vol. 55, no. 7, pp. 717-722Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0895-4356(02)00403-1