Professor Graeme MacLennan

Director (CHaRT)

Email Address: g.maclennan@abdn.ac.uk
Telephone Number: +44 (0)1224 438147
Office Address: Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD
School/Department: School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.

Qualifications

BSc Mathematics
1997 - University of Aberdeen
MSc Applied Statistics
2004 - Sheffield Hallam University

Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).

Research on making trials more efficient, collaborating with Trial Forge.

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

Page 5 of 11 Results 101 to 125 of 265

Economic evaluation of surgical treatments for women with stress urinary incontinence: a cost-utility and value of information analysis
2020 - Published
Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S., Ternent, L., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Becker, F., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L., Craig, D.
BMJ Open, vol. 10, no. 6, 035555
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2019-035555
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14489/1/Javanbakht_et_al_BMJOpen_EconomicEvaluationOf_VoR.pdf
- [ONLINE] View publication in Scopus
IDENTIFY: The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer: A multicentre cohort study
2020 - Published
Khadhouri, S., Gallagher, K. M., MacKenzie, K., Shah, T. T., Gao, C., Moore, S., Zimmermann, E., Edison, E., Jefferies, M., Nambiar, A., MacLennan, G., McGrath, J. S., Kasivisvanathan, V., IDENTIFY Protocol Collaborators Group
International Journal of Surgery Protocols, vol. 21, pp. 8-12
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.isjp.2020.02.002
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14328/1/1_s2.0_S246835742030005X_main.pdf
- [ONLINE] View publication in Scopus
ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes: protocol for the ELECTRIC randomised trial
2019 - Published
Booth, J., Aucott, L., Cotton, S., Goodman, C., Hagen, S., Harari, D., Lawrence, M., Lowndes, A., Macaulay, L., MacLennan, G., Mason, H., McClurg, D., Norrie, J., Norton, C., O'Dolan, C., Skelton, D. A., Surr, C., Treweek, S.
Trials, vol. 20, 723
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-019-3723-7
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13411/1/Booth_etal_Trials_ELECtric_Tibial_VOR.pdf
Practical help for specifying the target difference in sample size calculations for RCTs: The DELTA² five-stage study, including a workshop
2019 - Published
Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C., Maclennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., Vale, L. D.
Health Technology Assessment, vol. 23, no. 60
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta23600
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13466/1/HTA_3030850_VOR.pdf
- [ONLINE] View publication in Scopus
Methods to deal with missing data in area under the curve outcomes in randomised controlled trials: the OPEN trial case
2019 - Published
Goulao, B., MacLennan, G.
5th International Clinical Trials Methodology Conference, pp. 141-141
Contributions to Journals: Abstracts
- [ONLINE] DOI: https://doi.org/10.1186/s13063-019-3688-6
Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial
2019 - Published
Cooper, K., Breeman, S., Scott, N. W., Scotland, G., Clark, J., Hawe, J., Hawthorn, R., Phillips, K., MacLennan, G., Wileman, S., McCormack, K., Hernández, R. A., Norrie, J., Bhattacharya, S., HEALTH Study Group
The Lancet, vol. 394, no. 10207, pp. 1425-1436
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(19)31790-8
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13243/1/Cooper_etal_Lancet_Laparoscopic_supracervical_VOR.pdf
- [ONLINE] https://abdn.pure.elsevier.com/en/en/researchoutput/laparoscopic-supracervical-hysterectomy-versus-endometrial-ablation-for-women-with-heavy-menstrual-bleeding-health(20b3fd84-6e08-4603-beaf-87c88732a17a).html
- [ONLINE] View publication in Scopus
Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins
2019 - Published
Brittenden, J., Cooper, D., Dimitrova, M., Scotland, G., Cotton, S. C., Elders, A., MacLennan, G., Ramsay, C. R., Norrie, J., Burr, J. M., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Tassie, E., Francis, J., Campbell, M. K.
The New England Journal of Medicine, vol. 381, no. 10, pp. 912-922
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1056/NEJMoa1805186
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13810/1/NEJMFive_year_outcomes_Brittenden_at_al_VoR.pdf
- [ONLINE] Publisher permissions
- [ONLINE] http://www.ncbi.nlm.nih.gov/pubmed/31483962
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Photodynamic versus white light-guided treatment of non-muscle invasive bladder cancer: A study protocol for a randomised trial of clinical and cost-effectiveness
2019 - Published
Tandogdu, Z., Lewis, R., Duncan, A., Penegar, S., McDonald, A., Vale, L., Shen, J., Kelly, J. D., Pickard, R., N Dow, J., Ramsay, C., Mostafid, H., Mariappan, P., Nabi, G., Creswell, J., Lazarowicz, H., McGrath, J., Taylor, E., Clark, E., Maclennan, G., Norrie, J., Hall, E., Heer, R.
BMJ Open, vol. 9, no. 9, e22268
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2018-022268
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13118/1/Tangdogdu_et_al_bmj_photodynamic_versus_vor.pdf
- [ONLINE] View publication in Scopus
The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial
2019 - Published
Beard, D. J., Davies, L. J., Cook, J. A., MacLennan, G., Price, A., Kent, S., Hudson, J., Carr, A., Leal, J., Campbell, H., Fitzpatrick, R., Arden, N., Murray, D., Campbell, M. K., TOPKAT Study Group
The Lancet, vol. 394, no. 10200, pp. 746-756
Contributions to Journals: Articles
- [ONLINE] https://www.journalslibrary.nihr.ac.uk/programmes/hta/081408/#/
- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(19)31281-4
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12837/1/Beard_etal_lancet_clinical_costeffectiveness_VOR.pdf
Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds: Managing Adolescent first episode Psychosis: a feasibility study (MAPS)
2019 - Published
Pyle, M., Broome, M. R., Joyce, E., MacLennan, G., Norrie, J., Freeman, D., Fowler, D., Haddad, P. M., Shiers, D., Hollis, C., Smith, J., Liew, A., Byrne, R. E., French, P., Peters, S., Hudson, J., Davies, L., Emsley, R., Yung, A., Birchwood, M., Longden, E., Morrison, A. P.
Trials, vol. 20, 395
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-019-3506-1
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12603/1/s13063_019_3506_1.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-3506-1
- [ONLINE] View publication in Mendeley
Surgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials
2019 - Published
Imamura, M., Hudson, J., Wallace, S. A., MacLennan, G., Shimonovich, M., Omar, M. I., Javanbakht, M., Moloney, E., Becker, F., Ternent, L., Montgomery, I., Mackie, P., Saraswat, L., Monga, A., Vale, L., Craig, D., Brazzelli, M.
BMJ, vol. 365, l1842
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmj.l1842
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12387/1/bmj.l1842.full.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] http://www.bmj.com/lookup/doi/10.1136/bmj.l1842
- [ONLINE] View publication in Mendeley
Supporting Harm Reduction through Peer Support (SHARPS): Testing the feasibility and acceptability of a peer-delivered, relational intervention for people with problem substance use who are homeless, to improve health outcomes, quality of life and social functioning and reduce harms: Study protocol
2019 - Published
Parkes, T., Matheson, C., Carver, H., Budd, J., Liddell, D., Wallace, J., Pauly, B., Fotopoulou, M., Burley, A., Anderson, I., MacLennan, G., Foster, R.
Pilot and Feasibility Studies, vol. 5, 64
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s40814-019-0447-0
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14966/1/document_1_.pdf
- [ONLINE] View publication in Scopus
Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation
2019 - Published
Brazzelli, M., Javanbakht, M., Imamura, M., Hudson, J., Moloney, E., Becker, F., Wallace, S., Omar, M. I., Shimonovich, M., MacLennan, G., Ternent, L., Vale, L., Montgomery, I., Mackie, P., Saraswat, L., Monga, A., Craig, D.
Health Technology Assessment, vol. 23, no. 14, pp. 1-306
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta23140
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12177/1/Surgical_treatments_for_women_with_stress_urinary_incontinence.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
- [ONLINE] Pubmed Publication
399 - Surgical treatment for recurrent bulbar urethral stricture: A randomised open label superiority trial of open urethroplasty versus endoscopic urethrotomy (The OPEN Trial): Abstracts EAU19 – 34th Annual EAU Congress
2019 - Published
Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., Cook, J., McColl, E., Breckons, M., Vale, L., Forbes, R., Currer, S., Forrest, M., Wilkinson, J., Andrich, D., Barclay, S., Munday, A., N’Dow, J., Payne, S., Watkin, N., Pickard, R.
European Urology Supplements, vol. 18, no. 1, pp. e523
Contributions to Journals: Articles
- [ONLINE] http://www.sciencedirect.com/science/article/pii/S1569905619303884
- [ONLINE] DOI: https://doi.org/10.1016/S1569-9056
Cognitive-behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT
2019 - Published
Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., Norrie, J., Hudson, J., Bowe, S., French, P., Hutton, P., Byrne, R., Syrett, S., Dudley, R., McLeod, H. J., Griffiths, H., Barnes, T. R., Davies, L., Shields, G., Buck, D., Tully, S., Kingdon, D.
Health Technology Assessment, vol. 23, no. 7, pp. 1-144
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta23070
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12098/1/HTA_Report_3028539.pdf
- [ONLINE] View publication in Scopus
Open randomised trial of the (Arabin) pessary to prevent preterm birth in twin pregnancy with health economics and acceptability: STOPPIT-2-a study protocol
2019 - Published
Norman, J. E., Norrie, J., Maclennan, G., Cooper, D., Whyte, S., Burley, S. C., Smith, J. B., Shennan, A., Robson, S. C., Thornton, S., Kilby, M. D., Marlow, N., Stock, S. J., Bennett, P. R., Denton, J.
BMJ Open, vol. 8, no. 12, e026430
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2018-026430
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12319/1/Open_randomised_trial_.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT)
2019 - Published
Martin, K. R., Bachmair, E., Aucott, L., Dures, E., Emsley, R., Gray, S. R., Hewlett, S., Kumar, V., Lovell, K., Macfarlane, G. J., MacLennan, G., McNamee, P., Norrie, J., Paul, L., Ralston, S., Siebert, S., Wearden, A., White, P. D., Basu, N.
BMJ Open, vol. 9, no. 1, e026793
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2018-026793
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11860/1/Protocol_for_a_multicentre_randomised_controlled_parallel_group_trial.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation
2018 - Published
Avenell, A., Robertson, C., Skea, Z., Jacobsen, E., Boyers, D., Cooper, D., Aceves-Martins, M., Retat, L., Fraser, C., Aveyard, P., Stewart, F., MacLennan, G., Webber, L., Corbould, E., Xu, B., Jaccard, A., Boyle, B., Duncan, E., Shimonovich, M., de Bruin, M.
Health Technology Assessment, vol. 22, no. 68, pp. 1-286
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta22680
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11603/2/Avenell_etal_HTA_Bariatric_Surgery_Lifestyle_VOR.pdf
- [ONLINE] Corrigendum
Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation
2018 - Published
Brazzelli, M., Hernández, R., Sharma, P., Robertson, C., Shimonovich, M., MacLennan, G., Fraser, C., Jamieson, R., Vallabhaneni, S. R.
Health Technology Assessment, vol. 22, no. 72, pp. 1-220
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta22720
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11881/1/3021699.pdf
DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial
2018 - Published
Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C., MacLennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., Vale, L. D.
BMJ, vol. 363, k3750
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmj.k3750
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11672/1/bmj.k3750.full.pdf
- [ONLINE] View publication in Scopus
DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial
2018 - Published
Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C., Maclennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., Vale, L. D.
Trials, vol. 19, 606
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-018-2884-0
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11519/1/DELTA2_guidance_on_choosing_the_target_difference_and_undertaking_and_reporting_the_sample_size_calculation_for_a_randomised_controlled_trial.pdf
- [ONLINE] View publication in Scopus
COMPARISON OF NINE SURGICAL TREATMENTS FOR WOMEN WITH STRESS URINARY INCONTINENCE: A COST-EFFECTIVENESS AND VALUE OF INFORMATION ANALYSIS
2018 - Published
Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S. A., Ternent, L., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L., Craig, D.
11th Annual European UroGynaecological Association Congress
Contributions to Conferences: Abstracts
- [ONLINE] https://www.eugaoffice.org/wp-content/uploads/2021/02/11th_EUGA_Congress_2018-abstract_book.pdf
A Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence
2018 - Published
Javanbakht, M., Moloney, E., Craig, D., Brazzelli, M., Wallace, S., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L.
ICS 2018
Contributions to Conferences: Abstracts
Partial factorial trials: comparing methods for statistical analysis and economic evaluation
2018 - Published
Dakin, H. A., Gray, A. M., MacLennan, G. S., Morris, R. W., Murray, D. W.
Trials, vol. 19, 442
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-018-2818-x
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10986/1/Partial_factorial_trials.pdf
Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial
2018 - Published
Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., Norrie, J., Hudson, J., Bowe, S. E., French, P., Byrne, R., Syrett, S., Dudley, R., McLeod, H. J., Griffiths, H., Barnes, T. R. E., Davies, L., Kingdon, D., FOCUS trial group
The lancet. Psychiatry, vol. 5, no. 8, pp. 633-643
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/S2215-0366(18)30184-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10891/2/Morrison_etal_TLP_Cognitive_Behavioural_Therapy_VOR.pdf

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Biography

Qualifications

Research Overview

Current Research

Teaching Responsibilities

Economic evaluation of surgical treatments for women with stress urinary incontinence: a cost-utility and value of information analysis

IDENTIFY: The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer: A multicentre cohort study

ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes: protocol for the ELECTRIC randomised trial

Practical help for specifying the target difference in sample size calculations for RCTs: The DELTA² five-stage study, including a workshop

Methods to deal with missing data in area under the curve outcomes in randomised controlled trials: the OPEN trial case

Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial

Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins

Photodynamic versus white light-guided treatment of non-muscle invasive bladder cancer: A study protocol for a randomised trial of clinical and cost-effectiveness

The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial

Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds: Managing Adolescent first episode Psychosis: a feasibility study (MAPS)

Surgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials

Supporting Harm Reduction through Peer Support (SHARPS): Testing the feasibility and acceptability of a peer-delivered, relational intervention for people with problem substance use who are homeless, to improve health outcomes, quality of life and social functioning and reduce harms: Study protocol

Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation

399 - Surgical treatment for recurrent bulbar urethral stricture: A randomised open label superiority trial of open urethroplasty versus endoscopic urethrotomy (The OPEN Trial): Abstracts EAU19 – 34th Annual EAU Congress

Cognitive-behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT

Open randomised trial of the (Arabin) pessary to prevent preterm birth in twin pregnancy with health economics and acceptability: STOPPIT-2-a study protocol

Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT)

Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation

Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation

DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

COMPARISON OF NINE SURGICAL TREATMENTS FOR WOMEN WITH STRESS URINARY INCONTINENCE: A COST-EFFECTIVENESS AND VALUE OF INFORMATION ANALYSIS

A Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence

Partial factorial trials: comparing methods for statistical analysis and economic evaluation

Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial

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Contributions to Conferences

Contributions to Journals

Biography

Qualifications

Research Overview

Current Research

Teaching Responsibilities

Economic evaluation of surgical treatments for women with stress urinary incontinence: a cost-utility and value of information analysis

IDENTIFY: The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer: A multicentre cohort study

ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes: protocol for the ELECTRIC randomised trial

Practical help for specifying the target difference in sample size calculations for RCTs: The DELTA2 five-stage study, including a workshop

Methods to deal with missing data in area under the curve outcomes in randomised controlled trials: the OPEN trial case

Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial

Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins

Photodynamic versus white light-guided treatment of non-muscle invasive bladder cancer: A study protocol for a randomised trial of clinical and cost-effectiveness

The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial

Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds: Managing Adolescent first episode Psychosis: a feasibility study (MAPS)

Surgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials

Supporting Harm Reduction through Peer Support (SHARPS): Testing the feasibility and acceptability of a peer-delivered, relational intervention for people with problem substance use who are homeless, to improve health outcomes, quality of life and social functioning and reduce harms: Study protocol

Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation

399 - Surgical treatment for recurrent bulbar urethral stricture: A randomised open label superiority trial of open urethroplasty versus endoscopic urethrotomy (The OPEN Trial): Abstracts EAU19 – 34th Annual EAU Congress

Cognitive-behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT

Open randomised trial of the (Arabin) pessary to prevent preterm birth in twin pregnancy with health economics and acceptability: STOPPIT-2-a study protocol

Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT)

Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation

Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation

DELTA 2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

COMPARISON OF NINE SURGICAL TREATMENTS FOR WOMEN WITH STRESS URINARY INCONTINENCE: A COST-EFFECTIVENESS AND VALUE OF INFORMATION ANALYSIS

A Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence

Partial factorial trials: comparing methods for statistical analysis and economic evaluation

Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial

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Books and Reports

Chapters in Books, Reports and Conference Proceedings

Contributions to Conferences

Contributions to Journals

Practical help for specifying the target difference in sample size calculations for RCTs: The DELTA² five-stage study, including a workshop

DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial