Professor Graeme MacLennan
Director (CHaRT)
- About
-
- Email Address
- g.maclennan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438147
- Office Address
Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.
My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.
Qualifications
- BSc Mathematics1997 - University of Aberdeen
- MSc Applied Statistics2004 - Sheffield Hallam University
- Research
-
Research Overview
The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).
Research on making trials more efficient, collaborating with Trial Forge.
Current Research
A complete list of the CHaRT RCT portolio is available by clicking here
- Teaching
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Teaching Responsibilities
I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.
- Publications
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Page 5 of 10 Results 101 to 125 of 250
Open randomised trial of the (Arabin) pessary to prevent preterm birth in twin pregnancy with health economics and acceptability: STOPPIT-2-a study protocol
BMJ Open, vol. 8, no. 12, e026430Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2018-026430
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/12319/1/Open_randomised_trial_.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT)
BMJ Open, vol. 9, no. 1, e026793Contributions to Journals: ArticlesBariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation
Health Technology Assessment, vol. 22, no. 68, pp. 1-286Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta22680
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11603/2/Avenell_etal_HTA_Bariatric_Surgery_Lifestyle_VOR.pdf
- [ONLINE] Corrigendum
Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation
Health Technology Assessment, vol. 22, no. 72, pp. 1-220Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/hta22720
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11881/1/3021699.pdf
DELTA 2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial
BMJ, vol. 363, k3750Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.k3750
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11672/1/bmj.k3750.full.pdf
- [ONLINE] View publication in Scopus
DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial
Trials, vol. 19, 606Contributions to Journals: ArticlesCOMPARISON OF NINE SURGICAL TREATMENTS FOR WOMEN WITH STRESS URINARY INCONTINENCE: A COST-EFFECTIVENESS AND VALUE OF INFORMATION ANALYSIS
11th Annual European UroGynaecological Association CongressContributions to Conferences: AbstractsA Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence
ICS 2018Contributions to Conferences: AbstractsPartial factorial trials: comparing methods for statistical analysis and economic evaluation
Trials, vol. 19, 442Contributions to Journals: ArticlesCognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial
The lancet. Psychiatry, vol. 5, no. 8, pp. 633-643Contributions to Journals: ArticlesTreatment of Advanced Glaucoma Study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma—study protocol
British Journal of Ophthalmology, vol. 102, no. 7, pp. 922-928Contributions to Journals: ArticlesA Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence
Health Technology Assessment international 2018 Annual MeetingContributions to Conferences: AbstractsTISU: Extracorporeal shockwave lithotripsy, as first treatment option, compared with direct progression to ureteroscopic treatment, for ureteric stones: study protocol for a randomised controlled trial
Trials, vol. 19, no. 1, pp. 1-11Contributions to Journals: ArticlesCancer and vitamin D supplementation: a systematic review and meta-analysis
The American Journal of Clinical Nutrition, vol. 107, no. 4, pp. 652-663Contributions to Journals: ArticlesInstrumental variable methods for a binary outcome were used to informatively address non-compliance in a randomised trial in surgery
Journal of Clinical Epidemiology, vol. 96, pp. 126-132Contributions to Journals: ArticlesThe split-plot design was useful for evaluating complex, multi-level interventions but there is need for improvement in its design and report
Journal of Clinical Epidemiology, vol. 96, pp. 120-125Contributions to Journals: ArticlesSystematic Techniques to Enhance rEtention in Randomised controlled trials: the STEER study protocol
Trials, vol. 19, 197Contributions to Journals: ArticlesHow to resolve discrepancies when findings from randomized controlled trials and meta-analyses disagree?
33rd Annual EAU Congress 2018Contributions to Conferences: PostersMale synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): Study protocol for a randomised controlled trial
Trials, vol. 19, pp. 1-17Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s13063-018-2501-2
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10149/1/Trials.pdf
- [ONLINE] View publication in Scopus
Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease and cancer: a systematic review and meta-analysis
BMJ, vol. 359, j4849Contributions to Journals: ArticlesBayesian clinical trial designs: Another option for trauma trials?
The journal of trauma and acute care surgery, vol. 83, no. 4, pp. 736-741Contributions to Journals: ArticlesTHISTLE: trial of hands-on Interprofessional simulation training for local emergencies: a research protocol for a stepped-wedge clustered randomised controlled trial
BMC Pregnancy and Childbirth, vol. 17, 294Contributions to Journals: ArticlesThe SIMS trial: adjustable anchored single-incision mini-slings versus standard tension-free midurethral slings in the surgical management of female stress urinary incontinence. A study protocol for a pragmatic, multicentre, non-inferiority randomised controlled trial
BMJ Open, vol. 7, no. 8, pp. 1-18Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2016-015111
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9208/1/e015111.full.pdf
- [ONLINE] View publication in Scopus
Long-Term Randomized Trial of Intensive Versus Symptomatic Management in Paget's Disease of Bone: The PRISM-EZ Study
Journal of Bone and Mineral Research, vol. 32, no. 6, pp. 1165-1173Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/jbmr.3066
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10009/1/PRISM_EZ_.docx
Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree
European Urology, vol. 71, no. 5, pp. 811-819Contributions to Journals: Articles
