Trials A-Z
A
- AI-TRiPS: Artificial Intelligence in Trauma Risk Prediction System trial
- ALLEGRO: A placebo controlled randomised trial of intravenous lidocaine in accelerating gastrointestinal recovery after colorectal surgery
- AMETHYST: A multi-centre, double-blind, placebo-controlled randomised trial comparing a combination of methotrexate and mifepristone versus methotrexate alone as a medical treatment for tubal ectopic pregnancy
- ASICA: Achieving self-directed integrated Cancer Aftercare
B
- BICS: Bisoprolol in COPD study
- BRIDGE-IT: A randomised controlled trial to determine the effectiveness of bridging from emergency to regular contraception
C
- CATHETER II: Randomised Controlled Trial CompAring THE Clinical And CosT-Effectiveness Of VaRious Washout Policies Versus No Washout Policy In Preventing Catheter Associated Complications In Adults Living With Long-Term Catheters
- CATHETER: Types of urethral catheter for reducing symptomatic urinary tract infections in hospitalised adults requiring short-term catheterisation
- CF: Cysteamine in Cystic Fibrosis
- C-GALL: A randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of laparoscopic cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones
- CHESS: The Children’s Early Self-Care Support (CHESS) Trial
- CLASS: Comparison of LAser, Surgery and foam Sclerotherapy
- CSAW: Can Shoulder Arthroscopy Work? Is arthroscopic sub-acromial decompression (ASAD) more effective than arthroscopy only for shoulder pain?
D
- DIAMOND: Deep infiltrating endometriosis: management by medical treatment versus early surgery
- DRAM: Diagnostic Requesting Advisory Model
- DyNAMISM: Do Non-steroidal Anti-inflammatory drugs (NSAIDs) reduce the appearance of sacroiliac joint bone marrow oedema on MRI, in spondyloarthritis?
E
- EAGLE: Effectiveness in Angle-closure Glaucoma of Lens Extraction
- EDNA: Early Detection of Neovascular Age-related macular degeneration
- ELECTRIC: ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes
- ELIPSE: A randomised controlled trial comparing the clinical and cost-effectiveness of lymph node removal in patients undergoing curative surgery for localised high-risk Prostate Cancer
- EMPOWER: Early signs monitoring to prevent relapse and promote wellbeing, engagement and recovery
- eTHoS: Trial comparing stapled haemorrhoidopexy with traditional excisional surgery for haemorrhoidal disease
F
- FILMS: Full thickness macular hole and Internal Limiting Membrane peeling Study
- FOCCUS: A Pragmatic Multi-Centred Randomised Controlled Trial of Surgical HDU Care versus HDU Care Delivered in an ICU and Pre-Operative Fluid Loading in High-Risk Patients Undergoing Major Elective Surgery
- FOCUS: Focusing On Clozapine Unresponsive Symptoms
- FUTURE: Female Urgency, Trial of Urodynamics as Routine Evaluation; a superiority randomised clinical trial to evaluate the effectiveness and cost effectiveness of invasive urodynamic investigations in management of women with refractory overactive bladder symptoms
G
- GAPS: Graduated compression as an Adjunct to Pharmacoprophylaxis in Surgery
- GOT-IT: A pragmatic group sequential placebo controlled randomised trial to determine the effectiveness of Glyceryl trinitrate for retained placenta
H
- HEALTH: Hysterectomy or Endometrial AbLation Trial for Heavy menstrual bleeding: A multicentre randomised controlled trial comparing laparoscopic supra-cervical hysterectomy with second generation endometrial ablation for the treatment of heavy menstrual bleeding
- HEALTH Longer Term Follow Up
I
- IMOP: A randomised placebo controlled trial of outpatient cervical ripening with Isosorbide Mononitrate (IMN) prior to induction of labour - clinical trial with analyses of efficacy, cost effectiveness and acceptability
- IMPACT: Improving Abortion Care Trial
- IQuaD: Improving the Quality of Dentistry: A randomised controlled trial comparing oral hygiene advice and periodontal instrumentation for the prevention and management of periodontal disease in dentate adults attending dental primary care
K
- KAT: Knee Arthroplasty Trial
- KORAL: The effectiveness and cost-effectiveness of arthroscopic lavage in the treatment of osteoarthritis of the knee
L
- LAP HERNIA: Laparoscopic Techniques for Inguinal Hernia Repair
- LIFT: Lessening the Impact of Fatigue in inflammatory rheumatic diseases: a randomised clinical trial
- Liverhope: Safety & tolerability of the combination of simvastatin plus rifaximin in patients with decompensated cirrhosis: a multicenter, double-bling, placebo controlled randomised clinical trial (Liverhope Safety and Efficacy)
M
- MAmMOTH: The Maintaining Musculoskeletal Health Study
- MAPS: Men After Prostate Surgery
- MASTER: Male synthetic sling versus Artificial urinary Sphincter for men with urodynamic stress incontinence after prostate surgery: Evaluation by Randomised controlled trial
- MAVIS: Randomised trial of Mineral And VItamin Supplementation
- MELLOW BABIES: Does "Mellow Babies" improve the psychosocial health of mothers and their children? The Mellow Babies Trial
- MUSICIAN
N
O
P
- PANDOS: Pain AND Opioids after Surgery
- PARTIAL – a randomised trial of the clinical and cost effectiveness of complex PARTIAL vs radical nephrectomy for clinically localised renal cell carcinoma
- PHOTO: PHOTOdynamic versus white light-guided treatment of non-muscle invasive bladder cancer: A randomised trial of clinical and cost-effectiveness
- PINT: Postnatal Incontinence Trial
- PIP: Pulpotomy for the management of Irreversible Pulpitis in mature teeth
- POPPY: Pelvic Organ Prolapse PhysiotherapY
- PRaCTICaL: A Pragmatic Randomised Controlled Trial of Intensive Care post-discharge review clinics in improving Longer-term Outcomes from critical illness.
- PRISM: Paget's disease: a Randomised Trial of Intensive vs Symptomatic Management
- ProLong: The relationship of pregnancy and delivery with incontinence and prolapse - The ProLong Study
- PROSPECT: PROlapse Surgery: Pragmatic Evaluation and randomised Controlled Trial
- PUrE: The clinical and cost effectiveness of surgical interventions for stones in the lower calyx of the kidney:
Q
R
- RAACENO: Reducing Asthma Attacks in Children using Exhaled Nitric Oxide as a biomarker to inform treatment strategy - a randomised trial
- RECORD: Randomised Evaluation of Calcium and / OR vitamin D
- REFLECT: A Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose fluoride toothpaste in preventing and treating dental Caries in high-risk older adulTs
- REFLUX: Randomised Evaluation oF Laparoscopic sUrgery for refluX
- REGAL: Recurrence of Endometriosis: A randomised controlled trial of clinical and cost-effectiveness of Gonadotrophin Releasing Hormone Analogues with add-back hormone replacement therapy versus repeat Laparoscopic surgery
S
- SBT: Scottish Back Trial
- SCARLESS: Single Centre Appendectomy RCT: Laparoscopic vs Endoscopic Single-port Surgery
- SCRIPT: Selective Caries Removal In Posterior Teeth
- SHARPS: Effectiveness and cost-effectiveness of a peer-delivered, relational, harm reduction intervention to improve mental health, quality of life, and related outcomes, for people experiencing homelessness and substance use problems: The ‘SHARPS’ cluster randomised controlled trial
- SIGNET: Scottish multicentre trial of glutamine and selenium supplemented parenteral nutrition for critically ill patients
- SIMS: Single-incision adjustable mini-slings versus standard tension-free mid-urethral slings in the management of stress urinary incontinence: a pragmatic multicentre non-inferiority randomised controlled trial
- SPIROMAC: SPIROmetry to Manage Asthma in Children
- STARS: Scottish Trial of Arthroplasty or Reduction for Subcapital fractures
- STOPPIT: STudy Of Progesterone for the Prevention of preterm birth In Twins
- STOPPIT-2: An open randomised trial of the Arabin pessary to prevent preterm birth in twin pregnancy, with health economics and acceptability
- SUSPEND: Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre placebo controlled randomised trial of calcium channel blockers (nifedipine) and alpha blockers (tamsulosin)
T
- TAGS: Treatment of Advanced Glaucoma Study. A multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma
- The FOLLOW UP study - a natural experiment comparing the clinical and cost-effectiveness of follow-up strategies after radical treatment for prostate cancer
- THISTLE: Improving intrapartum outcomes for mothers and babies in Scotland: a stepped-wedge RCT of an intrapartum emergencies training package in 15 Scottish maternity units
- TISU: Therapeutic Interventions for Stones of the Ureter
- TOPKAT: Total or Partial Knee Arthroplasty Trial
- TOPSY: A multicentre randomised controlled trial, with nested process evaluation, to test the clinical and cost-effectiveness of self-management of vaginal pessaries to treat pelvic organ prolapse, compared to standard care to improve women's quality of life
- TRUCK: Explanatory comparative study of conventional Total Knee Arthroplasty versus Robotic assisted Bi-UniCompartmental Knee Arthroplasty
- TWICS: Theophylline with inhaled corticosteroids
U
- UK REBOA: A randomised controlled trial of the effectiveness, and cost-effectiveness, of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) for trauma
- UK TAVI: The United Kingdom Transcatheter Aortic Valve Implantation Trial
- UKUFF: The United Kingdom Rotator Cuff Trial
V
A
- AI-TRiPS: Artificial Intelligence in Trauma Risk Prediction System trial
- AMETHYST: A multi-centre, double-blind, placebo-controlled randomised trial comparing a combination of methotrexate and mifepristone versus methotrexate alone as a medical treatment for tubal ectopic pregnancy
C
D
E
F
H
K
M
P
- PANDOS: Pain AND Opioids after Surgery
- PARTIAL – a randomised trial of the clinical and cost effectiveness of complex PARTIAL vs radical nephrectomy for clinically localised renal cell carcinoma
- PIP: Pulpotomy for the management of Irreversible Pulpitis in mature teeth
- ProLong: The relationship of pregnancy and delivery with incontinence and prolapse - The ProLong Study
- PROSPECT: PROlapse Surgery: Pragmatic Evaluation and randomised Controlled Trial
- PUrE: The clinical and cost effectiveness of surgical interventions for stones in the lower calyx of the kidney:
R
- REFLECT: A Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose fluoride toothpaste in preventing and treating dental Caries in high-risk older adulTs
- REGAL: Recurrence of Endometriosis: A randomised controlled trial of clinical and cost-effectiveness of Gonadotrophin Releasing Hormone Analogues with add-back hormone replacement therapy versus repeat Laparoscopic surgery
S
- SCRIPT: Selective Caries Removal In Posterior Teeth
- SHARPS: Effectiveness and cost-effectiveness of a peer-delivered, relational, harm reduction intervention to improve mental health, quality of life, and related outcomes, for people experiencing homelessness and substance use problems: The ‘SHARPS’ cluster randomised controlled trial
- SIMS: Single-incision adjustable mini-slings versus standard tension-free mid-urethral slings in the management of stress urinary incontinence: a pragmatic multicentre non-inferiority randomised controlled trial
- SPIROMAC: SPIROmetry to Manage Asthma in Children
T
- TAGS: Treatment of Advanced Glaucoma Study. A multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma
- The FOLLOW UP study - a natural experiment comparing the clinical and cost-effectiveness of follow-up strategies after radical treatment for prostate cancer
- THISTLE: Improving intrapartum outcomes for mothers and babies in Scotland: a stepped-wedge RCT of an intrapartum emergencies training package in 15 Scottish maternity units
- TOPSY: A multicentre randomised controlled trial, with nested process evaluation, to test the clinical and cost-effectiveness of self-management of vaginal pessaries to treat pelvic organ prolapse, compared to standard care to improve women's quality of life
- TRUCK: Explanatory comparative study of conventional Total Knee Arthroplasty versus Robotic assisted Bi-UniCompartmental Knee Arthroplasty
U
V
A
- ALLEGRO: A placebo controlled randomised trial of intravenous lidocaine in accelerating gastrointestinal recovery after colorectal surgery
- ASICA: Achieving self-directed integrated Cancer Aftercare
B
- BICS: Bisoprolol in COPD study
- BRIDGE-IT: A randomised controlled trial to determine the effectiveness of bridging from emergency to regular contraception
C
- CATHETER II: Randomised Controlled Trial CompAring THE Clinical And CosT-Effectiveness Of VaRious Washout Policies Versus No Washout Policy In Preventing Catheter Associated Complications In Adults Living With Long-Term Catheters
- CATHETER: Types of urethral catheter for reducing symptomatic urinary tract infections in hospitalised adults requiring short-term catheterisation
- CF: Cysteamine in Cystic Fibrosis
- C-GALL: A randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of laparoscopic cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones
- CLASS: Comparison of LAser, Surgery and foam Sclerotherapy
- CSAW: Can Shoulder Arthroscopy Work? Is arthroscopic sub-acromial decompression (ASAD) more effective than arthroscopy only for shoulder pain?
D
- DIAMOND: Deep infiltrating endometriosis: management by medical treatment versus early surgery
- DRAM: Diagnostic Requesting Advisory Model
E
- EAGLE: Effectiveness in Angle-closure Glaucoma of Lens Extraction
- EDNA: Early Detection of Neovascular Age-related macular degeneration
- ELECTRIC: ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes
- EMPOWER: Early signs monitoring to prevent relapse and promote wellbeing, engagement and recovery
- eTHoS: Trial comparing stapled haemorrhoidopexy with traditional excisional surgery for haemorrhoidal disease
F
- FILMS: Full thickness macular hole and Internal Limiting Membrane peeling Study
- FOCCUS: A Pragmatic Multi-Centred Randomised Controlled Trial of Surgical HDU Care versus HDU Care Delivered in an ICU and Pre-Operative Fluid Loading in High-Risk Patients Undergoing Major Elective Surgery
- FOCUS: Focusing On Clozapine Unresponsive Symptoms
G
- GAPS: Graduated compression as an Adjunct to Pharmacoprophylaxis in Surgery
- GOT-IT: A pragmatic group sequential placebo controlled randomised trial to determine the effectiveness of Glyceryl trinitrate for retained placenta
H
I
- IMOP: A randomised placebo controlled trial of outpatient cervical ripening with Isosorbide Mononitrate (IMN) prior to induction of labour - clinical trial with analyses of efficacy, cost effectiveness and acceptability
- IMPACT: Improving Abortion Care Trial
- IQuaD: Improving the Quality of Dentistry: A randomised controlled trial comparing oral hygiene advice and periodontal instrumentation for the prevention and management of periodontal disease in dentate adults attending dental primary care
K
L
- LAP HERNIA: Laparoscopic Techniques for Inguinal Hernia Repair
- LIFT: Lessening the Impact of Fatigue in inflammatory rheumatic diseases: a randomised clinical trial
- Liverhope: Safety & tolerability of the combination of simvastatin plus rifaximin in patients with decompensated cirrhosis: a multicenter, double-bling, placebo controlled randomised clinical trial (Liverhope Safety and Efficacy)
M
- MAmMOTH: The Maintaining Musculoskeletal Health Study
- MAPS: Men After Prostate Surgery
- MAVIS: Randomised trial of Mineral And VItamin Supplementation
- MELLOW BABIES: Does "Mellow Babies" improve the psychosocial health of mothers and their children? The Mellow Babies Trial
- MUSICIAN
N
O
P
- PHOTO: PHOTOdynamic versus white light-guided treatment of non-muscle invasive bladder cancer: A randomised trial of clinical and cost-effectiveness
- PINT: Postnatal Incontinence Trial
- POPPY: Pelvic Organ Prolapse PhysiotherapY
- PRaCTICaL: A Pragmatic Randomised Controlled Trial of Intensive Care post-discharge review clinics in improving Longer-term Outcomes from critical illness.
- PRISM: Paget's disease: a Randomised Trial of Intensive vs Symptomatic Management
Q
R
- RAACENO: Reducing Asthma Attacks in Children using Exhaled Nitric Oxide as a biomarker to inform treatment strategy - a randomised trial
- RECORD: Randomised Evaluation of Calcium and / OR vitamin D
- REFLUX: Randomised Evaluation oF Laparoscopic sUrgery for refluX
S
- SBT: Scottish Back Trial
- SCARLESS: Single Centre Appendectomy RCT: Laparoscopic vs Endoscopic Single-port Surgery
- SIGNET: Scottish multicentre trial of glutamine and selenium supplemented parenteral nutrition for critically ill patients
- STARS: Scottish Trial of Arthroplasty or Reduction for Subcapital fractures
- STOPPIT: STudy Of Progesterone for the Prevention of preterm birth In Twins
- STOPPIT-2: An open randomised trial of the Arabin pessary to prevent preterm birth in twin pregnancy, with health economics and acceptability
- SUSPEND: Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre placebo controlled randomised trial of calcium channel blockers (nifedipine) and alpha blockers (tamsulosin)
T
- TISU: Therapeutic Interventions for Stones of the Ureter
- TOPKAT: Total or Partial Knee Arthroplasty Trial
- TWICS: Theophylline with inhaled corticosteroids
U