![Dr Anke Roelofs Dr Anke Roelofs](/img/200x200/staffpages/uploads/mmd718/avatar/XThpNUVmJR3rZqQbgleJehPh6j8IwBWF2WTBQFhk.jpeg)
MSc, DPhil, FHEA
Senior Lecturer
- About
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- Email Address
- a.roelofs@abdn.ac.uk
- Office Address
Arthritis and Regenerative Medicine Group
Room 3:16
Institute of Medical Sciences
Foresterhill
Aberdeen AB25 2ZD- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I completed my MSc in Biology, with specialisation in Medical Biology, at the University of Groningen in the Netherlands in 2003 cum laude (first class). I then moved to the University of Oxford, where I obtained my DPhil in Medical Science in 2007. I continued my post-doctoral research career at the University of Aberdeen, where I am currently Senior Lecturer in Skeletal Regenerative Medicine. I am a member of the Arthritis and Regenerative Medicine team within the Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH).
Qualifications
- MSc Biology2003 - University of Groningen
- DPhil Medical Sciences2007 - University of Oxford
- FHEA Fellow of the Higher Education Academy2023 - Advance HE
- Research
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Current Research
My current research interests are centered around synovial joint biology, with a particular focus on the roles of adult stem cells in joint maintenance, repair, and disease. We seek to enhance our understanding of the identity, ontogeny, regulation and functions of stem cells in the joint using approaches such as genetic cell lineage tracing and scRNA-seq. Our ultimate aim is to develop novel treatments that target endogenous stem cells to promote skeletal joint health and regeneration.
Please visit our Arthritis and Regenerative Medicine page to find out more about our team and the research that we do.
- Teaching
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Programmes
- Postgraduate, 3 stage, September start
Programme coordinator
Courses
Course coordinator
- Student Selected Component 1 (ME2511)
- Publications
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Recognition and control of neutrophil extracellular trap formation by MICL
NatureContributions to Journals: ArticlesDisentangling the detrimental effects of local from systemic adipose tissue dysfunction on articular cartilage in the knee
Osteoarthritis and CartilageContributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.joca.2024.07.006
Vascular disease persistence in giant cell arteritis: are stromal cells neglected?
Annals of the Rheumatic DiseasesContributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1136/ard-2023-225270
Osteoarthritis year in review 2023: Biology
Osteoarthritis and Cartilage, vol. 32, no. 2, pp. 148-158Contributions to Journals: ArticlesBMP signalling: A significant player and therapeutic target for osteoarthritis
Osteoarthritis and Cartilage, vol. 31, no. 11, pp. 1454-1468Contributions to Journals: ArticlesSpatial lipidomic profiling of mouse joint tissue demonstrates the essential role of PHOSPHO1 in growth plate homeostasis
Journal of Bone and Mineral Research, vol. 38, no. 5, pp. 792-807Contributions to Journals: ArticlesTaxonomy of fibroblasts and progenitors in the synovial joint at single-cell resolution
Annals of the Rheumatic Diseases, vol. 82, no. 3, pp. 428-437Contributions to Journals: ArticlesCellular therapy and tissue engineering for cartilage repair
Osteoarthritis and Cartilage, vol. 30, no. 12, pp. 1547-1560Contributions to Journals: Review articlesTargeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis
Annals of the Rheumatic Diseases, vol. 81, no. 2, pp. 214-224Contributions to Journals: ArticlesHuman Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model
Cells, vol. 10, no. 8, 1999Contributions to Journals: Articles