Professor Mary MacLeod

BSc MBChB PhD FRCP

Personal Chair (Clinical)

Email Address: m.j.macleod@abdn.ac.uk
Telephone Number: +44 (0)1224 437842
School/Department: School of Medicine, Medical Sciences and Nutrition

Biography

Dr Macleod is a Clinical Pharmacologist with a personal chair (Teaching and Research) at the University of Aberdeen and honorary Consultant Physician within NHS Grampian. Her clinical work is largely in the area of acute stroke management, hypertension clinics and primary and secondary cardiovascular prevention. Current research interests include:

Novel imaging markers in stroke and small vessel disease using fast field cycling MRI

Using linked datasets to explore management of stroke including service organisation and secondary prevention

Interactions between stroke and other diseases (e.g. cancer)

Memberships and Affiliations

Internal Memberships: Chair, Clinical Studies Oversight Group
External Memberships: Chair of Scotland A and B Research Ethics Committees

Honorary Deputy Secretary, British and Irish Association of Stroke Physicians

Trustee SHARP (Scottish Heart and Arterial Disease Prevention)

Latest Publications

Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial
2024 - Published
Muir, K. W., Ford, G. A., Ford, I., Wardlaw, J. M., McConnachie, A., Greenlaw, N., Mair, G., Sprigg, N., Price, C. I., MacLeod, M. J., Dima, S., Venter, M., Zhang, L., O’Brien, E., Sanyal, R., Reid, J., Sztriha, L. K., Haider, S., Whiteley, W. N., Kennedy, J., Perry, R., Lakshmanan, S., Chakrabarti, A., Hassan, A., Marigold, R., Raghunathan, S., Sims, D., Bhandari, M., Wiggam, I., Rashed, K., Douglass, C., ATTEST-2 Investigators
The Lancet neurology, vol. 23, no. 11, pp. 1087-1096
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/S1474-4422(24)00377-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24433/1/Muir_etal_TLN_Tenecteplase_Versus_Alteplase_VoR.pdf
Field-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T
2024 - Published
Mallikourti, V., Ross, P. J., Maier, O., Guzman-Gutierrez, G., Franko, E., Lurie, D. J., Broche, L. M., Macleod, M. J.
Radiology, vol. 312, no. 2, e232972
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1148/radiol.232972
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24218/1/Mallikourti_etal_R_Field_Cycling_MRI_For_VOR.pdf
- [ONLINE] View publication in Scopus
Acute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study
2024 - E-pub ahead of print
Sterling, K., Macleod, M., Barber, M., Turner, M.
Cerebrovascular Diseases
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1159/000540371
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24484/1/Sterling_etal_CD_Acute_Care_Secondary_VoR.pdf
Field-Cycling Magnetic Resonance Imaging for identifying Minor Ischemic Stroke below 0.2 tesla
2024 - Accepted/In press
Ross, J., Mallikourti, V., Maier, O., Guzman Gutierrez, G., Franko, E., Lurie, D., Broche, L., Macleod, M.
Radiology
Contributions to Journals: Articles
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23512/1/Ross_R_Field-Cycling_Magnetic_Resonance_AAM.pdf
Does following an “excellent” candidate in the Objective Structured Clinical Examination affect your checklist score?
2024 - Published
Brown, C. W., Watson, W., Macleod, M., Nath, M.
Journal of Applied Research in Higher Education
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1108/JARHE-02-2023-0079
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/21557/1/Brown_etal_JARHE_Does_Following_an_Excellent_AAM.pdf

View My Publications

Teaching

Teaching Responsibilities

Year 5 MBChB OSCE coordinator

Situational Judgement Test lead

Year 1, 3 and 4 Clinical Pharmacology teaching

MSc Clinical Pharmacology: Pharmacovigilance, Medicines Management

Delivers teaching to MSc Cardiovascular and Diabetes, BSc Neurosciences, BSc Genetics

MRCP PACES examiner

Publications

Update

Biography

Memberships and Affiliations

Latest Publications

Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial

Field-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T

Acute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study

Field-Cycling Magnetic Resonance Imaging for identifying Minor Ischemic Stroke below 0.2 tesla

Does following an “excellent” candidate in the Objective Structured Clinical Examination affect your checklist score?

Teaching Responsibilities

Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial

Field-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T

Acute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study

Field-Cycling Magnetic Resonance Imaging for identifying Minor Ischemic Stroke below 0.2 tesla

Does following an “excellent” candidate in the Objective Structured Clinical Examination affect your checklist score?

Allopurinol and Blood Pressure Variability Following Ischemic Stroke and Transient Ischemic Attack: A Secondary Analysis of XILO-FIST

Associations Between Prior Oral Anticoagulant Use and Stroke Outcomes in a National Stroke Cohort: A Scottish Database Study

Association between pre-stroke comorbidity and post-stroke prescribing in a Scottish ischaemic stroke survivor population:: A national data linkage study

Randomised Trial of Tenectplase versus Alteplase for Acute Stroke within 4.5h of onset: the second Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST-2)

Assessing severity of cerebral small vessel disease using field-cycling MRI and automated segmentation

Detection of haematoma and peri-haematomal regions of intracerebral haemorrhage using lowfield field-cycling imaging – preliminary study results

Trends in intracerebral haemorrhage admissions, prior anticoagulant use, acute stroke care, and mortality outcomes 2011-2018:: A national Scottish database study.

Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history and potential treatments from translation to clinical trials

Detection of cerebral small vessel disease using denoised field-cycling MRI: Book of Abstracts ESMRMB 2023

Phase II randomised, placebo-controlled, clinical trial of interleukin-1 receptor antagonist in intracerebral haemorrhage: BLOcking the Cytokine IL-1 in ICH (BLOC-ICH)

Automated segmentation of cerebral small vessel disease from field-cycling MRI: Proffered Conference Abstract - MIUA 2023

Does following an “excellent” candidate in the Objective Structured Clinical Examination (OSCE) affect your checklist score?

Antithrombotic use and mortality outcomes in ischaemic stroke patients with atrial fibrillation: a Scottish database study

Xanthine oxidase inhibition and white matter hyperintensity progression following ischaemic stroke and transient ischaemic attack (XILO-FIST): a multicentre, double-blinded, randomised, placebo-controlled trial

Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19-a data-driven retrospective cohort study

Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial

Is stroke incidence increased in survivors of adult cancers?: A systematic review and meta-analysis

Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial

Intravenous Thrombolysis with Tenecteplase for the Treatment of Acute Ischemic Stroke

Phasic alertness and multisensory integration contribute to visual awareness of weak visual targets in audio-visual stimulation under Continuous Flash Suppression

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