Professor Mary MacLeod

BSc MBChB PhD FRCP

Personal Chair (Clinical)

Email Address: m.j.macleod@abdn.ac.uk
Telephone Number: +44 (0)1224 437842
School/Department: School of Medicine, Medical Sciences and Nutrition

Biography

Dr Macleod is a Clinical Pharmacologist with a personal chair (Teaching and Research) at the University of Aberdeen and honorary Consultant Physician within NHS Grampian. Her clinical work is largely in the area of acute stroke management, hypertension clinics and primary and secondary cardiovascular prevention. Current research interests include:

Novel imaging markers in stroke and small vessel disease using fast field cycling MRI

Using linked datasets to explore management of stroke including service organisation and secondary prevention

Interactions between stroke and other diseases (e.g. cancer)

Memberships and Affiliations

Internal Memberships: Chair, Clinical Studies Oversight Group
External Memberships: Chair of Scotland A and B Research Ethics Committees

Honorary Deputy Secretary, British and Irish Association of Stroke Physicians

Trustee SHARP (Scottish Heart and Arterial Disease Prevention)

Latest Publications

Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial
2024 - Published
Muir, K. W., Ford, G. A., Ford, I., Wardlaw, J. M., McConnachie, A., Greenlaw, N., Mair, G., Sprigg, N., Price, C. I., MacLeod, M. J., Dima, S., Venter, M., Zhang, L., O’Brien, E., Sanyal, R., Reid, J., Sztriha, L. K., Haider, S., Whiteley, W. N., Kennedy, J., Perry, R., Lakshmanan, S., Chakrabarti, A., Hassan, A., Marigold, R., Raghunathan, S., Sims, D., Bhandari, M., Wiggam, I., Rashed, K., Douglass, C., ATTEST-2 Investigators
The Lancet neurology, vol. 23, no. 11, pp. 1087-1096
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/S1474-4422(24)00377-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24433/1/Muir_etal_TLN_Tenecteplase_Versus_Alteplase_VoR.pdf
Field-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T
2024 - Published
Ross, J., Mallikourti, V., Maier, O., Guzman Gutierrez, G., Franko, E., Lurie, D., Broche, L., Macleod, M.
Radiology, vol. 312, no. 2, e232972
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1148/radiol.232972
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23512/3/Mallikourti_etal_R_Field_Cycling_MRI_For_VOR.pdf
- [ONLINE] View publication in Scopus
Acute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study
2024 - E-pub ahead of print
Sterling, K., MacLeod, M., Barber, M., Turner, M.
Cerebrovascular Diseases
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1159/000540371
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24484/1/Sterling_etal_CD_Acute_Care_Secondary_VoR.pdf
Randomised Trial of Tenecteplase versus Alteplase for Acute Stroke within 4.5h of onset: the second Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST-2)
2024 - Published
Muir, K., Ford, G., Ford, I., Wardlaw, J., McConnachie, A., Greenlaw, N., Price, C. I., Macleod, M., Dima, S., Venter, M., Zhang, L., O’Brien, E., Sanyal, R., Reid, J., Sztriha, L., Haider, S., Whiteley, W. N., Kennedy, J., Perry, R., Sekaran, L., Chakrabarti, A., Hassan, A., Marigold, R., Raghunathan, S., Sims, D., Bhandari, M., Douglass, C., ATTEST-2 Investigators
Working Papers: Preprint Papers
- [ONLINE] DOI: https://doi.org/10.2139/ssrn.4831843
- [ONLINE] https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4831843
Does following an “excellent” candidate in the Objective Structured Clinical Examination affect your checklist score?
2024 - Published
Brown, C. W., Watson, W., Macleod, M., Nath, M.
Journal of Applied Research in Higher Education, vol. 16, no. 3, pp. 891-903
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1108/JARHE-02-2023-0079
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/21557/1/Brown_etal_JARHE_Does_Following_an_Excellent_AAM.pdf

View My Publications

Teaching

Teaching Responsibilities

Year 5 MBChB OSCE coordinator

Situational Judgement Test lead

Year 1, 3 and 4 Clinical Pharmacology teaching

MSc Clinical Pharmacology: Pharmacovigilance, Medicines Management

Delivers teaching to MSc Cardiovascular and Diabetes, BSc Neurosciences, BSc Genetics

MRCP PACES examiner

Publications

Update

Biography

Memberships and Affiliations

Latest Publications

Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial

Field-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T

Acute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study

Randomised Trial of Tenecteplase versus Alteplase for Acute Stroke within 4.5h of onset: the second Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST-2)

Does following an “excellent” candidate in the Objective Structured Clinical Examination affect your checklist score?

Teaching Responsibilities

The Association of Atrial Fibrillation and Ischemic Stroke in Patients on Hemodialysis: A Competing Risk Analysis

The positive predictive value of an ambulance prealert for stroke and transient ischaemic attack

A novel imaging modality (Fast Field-Cycling MRI) identifies ischaemic stroke at ultra-low magnetic field strength

Fast Field-Cycling MRI technology: prototype human scanner and first clinical results

Renal replacement modality and stroke risk in end-stage renal disease-a national registry study

Inequality in Care and Differences in Outcome Following Stroke in People With ESRD

THE MEDICINES ACT 1968 – 20 50 YEARS ON

Intravenous Thrombolysis for Ischemic Stroke Patients on Dual Antiplatelets

Practice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study

The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: Study protocol for a randomised controlled trial

Abstract WP255: Omega-3 Fatty Acids as a Treatment for Experimental Ischaemic Stroke: A Systematic Review and Meta-analysis

The Influence of Diabetes on Subtype, Treatment and Outcome in Stroke Patients in Scotland

Avoiding unseen obstacles: Subcortical vision is not sufficient to maintain normal obstacle avoidance behaviour during reaching

The effects of stroke severity on door-to-needle time delays - a retrospective analysis

Marine-derived n-3 fatty acids therapy for stroke

Simple prediction scores predict good and devastating outcomes after stroke more accurately than physicians

Reasons for non-recruitment of eligible patients to a randomised controlled trial of secondary prevention after intracerebral haemorrhage: observational study

The cost savings of newer oral anticoagulants in atrial fibrillation-related stroke prevention

Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis

Angina and Future Cardiovascular Events in Stable Patients With Coronary Artery Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry

Stroke: Are care and outcomes better for participants of stroke trials?

Stroke patients admitted within normal working hours are more likely to achieve process standards and to have better outcomes

Disappearance of the hyperdense MCA sign after stroke thrombolysis: implications for prognosis and early patient selection for clot retrieval

Cause of Death and Predictors of All‐Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF

Agreement between routine electronic hospital discharge and Scottish Stroke Care Audit (SSCA) data in identifying stroke in the Scottish population

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