Mr Gary Duncan

Mr Gary Duncan
Mr Gary Duncan
Mr Gary Duncan

Research Technician

About

Biography

Gary has over 25 years of Mass Spectrometry experience.  He started work at what was then the Rowett Research Institute in 1986, and after six weeks training in analytical techniques, started working in the Gas Isotope Ratio Mass Spectrometry (GIRMS) laboratory assisting Dr Brian McGaw and Mr Eric Milne. As interest in this technique grew, the lab eventually had four mass spectrometers dedicated to analysing the stable isotopes of Carbon, Hydrogen and Oxygen from a variety of biological sources, supporting research into energy expenditure and protein synthesis. The research programmes of the Rowett then required Liquid Chromatography Mass Spectrometry (LC/MS) and a MAT 900 double-sector LC-MS/MS system was purchased in 1998, along with a LaserMAT MALDI mass spectrometer. Initially his role was to develop techniques for sample analysis on the MALDI, but soon took over the role of managing the LC/MS mass facility. This coincided with a ‘take-off’ in the popularity of using LCMSMS in sample analysis, firstly in the growth of identifying proteins separated on 2D gels and more recently the targeted quantitation analysis of small molecules. The main areas of analysis are in the quantification of Polyphenols relating to dietary consumption and human health and the quantification of Mycotoxins in foods and crops, in particular, the detoxification of Deoxynivalenol. The LCMSMS facility now has four mass spectrometers, with access to an ion trap to support work in these areas of research.

Other Areas of interest include:

  • Vitamin D3
  • Methylamines
  • Anthocyanins
  • Nicotinamides
  • Carboxymethyl Lysines
  • Antibiotics

Latest Publications

View My Publications

Publications

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  • Balancing Inflammatory, Lipid, and Xenobiotic Signaling Pathways by VSL#3, a Biotherapeutic Agent, in the Treatment of Inflammatory Bowel Disease

    Reiff, C., Delday, M., Rucklidge, G., Reid, M., Duncan, G., Wohlgemuth, S., Hoermannsperger, G., Loh, G., Blaut, M., Collie-Duguid, E., Haller, D., Kelly, D.
    Inflammatory Bowel Diseases, vol. 15, no. 11, pp. 1721-1736
    Contributions to Journals: Articles
  • Gene and protein expression profiles in the foetal liver of the pregnant rat fed a low protein diet

    McNeil, C. J., Hay, S. M., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Rees, W. D.
    Genes & Nutrition, vol. 4, no. 3, pp. 189-194
    Contributions to Journals: Articles
  • Phenolic acid content of fruits commonly consumed and locally produced in Scotland

    Russell, W. R., Labat, A., Scobbie, L., Duncan, G. J., Duthie, G. G.
    Food Chemistry, vol. 115, no. 1, pp. 100-104
    Contributions to Journals: Articles
  • Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet

    de Roos, B., Rungapamestry, V., Ross, K., Rucklidge, G., Reid, M., Duncan, G., Horgan, G., Toomey, S., Browne, J., Loscher, C. E., Mills, K. H. G., Roche, H. M.
    Proteomics, vol. 9, no. 12, pp. 3244-3256
    Contributions to Journals: Articles
  • The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses

    Duthie, S. J., Mavrommatis, Y., Rucklidge, G., Reid, M., Duncan, G., Moyer, M. P., Pirie, L. P., Bestwick, C. S.
    Journal of Proteome Research, vol. 7, no. 8, pp. 3254-3266
    Contributions to Journals: Articles
  • Aorta protein networks in marginal and acute zinc deficiency

    Beattie, J. H., Gordon, M. J., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Horgan, G. W., Cho, Y., Kwun, I.
    Proteomics, vol. 8, no. 10, pp. 2126-2135
    Contributions to Journals: Articles
  • Identification of potential serum biomarkers of inflammation and lipid modulation that are altered by fish oil supplementation in healthy volunteers

    De Roos, B., Geelen, A., Ross, K., Rucklidge, G., Reid, M., Duncan, G., Caslake, M., Horgan, G., Brouwer, I. A.
    Proteomics, vol. 8, no. 10, pp. 1965-1974
    Contributions to Journals: Articles
  • Disruption of lipid metabolism in the liver of the pregnant rat fed folate-deficient and methyl donor-deficient diets

    McNeil, C. J., Hay, S., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Maloney, C. A., Rees, W.
    British Journal of Nutrition, vol. 99, no. 2, pp. 262-271
    Contributions to Journals: Articles
  • Profiling of mitochondrial associated proteins from rat colon

    Padidar, S., Bestwick, C., King, T. P., Rucklidge, G. J., Duncan, G. J., Reid, M. D., Drew, J.
    Journal of Cellular Biochemistry, vol. 103, no. 1, pp. 78-97
    Contributions to Journals: Articles
  • The effects of fish oil and DHA on soluble epoxide hydrolase in apoE-/- mice

    Mavrommatis, Y. I., Thies, F., Ross, K., Gordon, M. J., McLeod, E., Sneddon, A. A., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Mayer, C., Horgan, G., Arthur, J., De Roos, B.
    Proceedings of the Nutrition Society, vol. 66, no. Supplement OCA-B , 103A
    Contributions to Journals: Abstracts
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