Research Technician
- About
-
- Email Address
- gary.duncan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438669
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Gary has over 25 years of Mass Spectrometry experience. He started work at what was then the Rowett Research Institute in 1986, and after six weeks training in analytical techniques, started working in the Gas Isotope Ratio Mass Spectrometry (GIRMS) laboratory assisting Dr Brian McGaw and Mr Eric Milne. As interest in this technique grew, the lab eventually had four mass spectrometers dedicated to analysing the stable isotopes of Carbon, Hydrogen and Oxygen from a variety of biological sources, supporting research into energy expenditure and protein synthesis. The research programmes of the Rowett then required Liquid Chromatography Mass Spectrometry (LC/MS) and a MAT 900 double-sector LC-MS/MS system was purchased in 1998, along with a LaserMAT MALDI mass spectrometer. Initially his role was to develop techniques for sample analysis on the MALDI, but soon took over the role of managing the LC/MS mass facility. This coincided with a ‘take-off’ in the popularity of using LCMSMS in sample analysis, firstly in the growth of identifying proteins separated on 2D gels and more recently the targeted quantitation analysis of small molecules. The main areas of analysis are in the quantification of Polyphenols relating to dietary consumption and human health and the quantification of Mycotoxins in foods and crops, in particular, the detoxification of Deoxynivalenol. The LCMSMS facility now has four mass spectrometers, with access to an ion trap to support work in these areas of research.
Other Areas of interest include:
- Vitamin D3
- Methylamines
- Anthocyanins
- Nicotinamides
- Carboxymethyl Lysines
- Antibiotics
Latest Publications
Persimmon Fiber-Rich Ingredients Promote Anti-Inflammatory Responses and the Growth of Beneficial Anti-Inflammatory Firmicutes Species from the Human Colon
Nutrients, vol. 16, no. 15, 2518Contributions to Journals: ArticlesBuckwheat (Fagopyrum esculentum) Hulls Are a Rich Source of Fermentable Dietary Fibre and Bioactive Phytochemicals: International Journal of Molecular Sciences
International Journal of Molecular Sciences, vol. 24, no. 22, 16310Contributions to Journals: ArticlesHabitual consumption of high-fibre bread fortified with bean hulls increased plasma indole-3-propionic concentration and decreased putrescine and deoxycholic acid faecal concentrations in healthy volunteers
British Journal of Nutrition, vol. 130, no. 9, pp. 1521-1536Contributions to Journals: ArticlesBioprocessing of Hempseed (Cannabis sativa L.) Food By-Products Increased Nutrient and Phytochemical In Vitro Bioavailability during Digestion and Microbial Fermentation
Applied Sciences, vol. 13, no. 9, 5781Contributions to Journals: ArticlesFree and Modified Mycotoxins in Organic and Conventional Oats (Avena sativa L.) Grown in Scotland
Toxins, vol. 15, no. 4, 247Contributions to Journals: Articles
- Publications
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Page 4 of 6 Results 31 to 40 of 60
A methyl-deficient diet fed to rats during the pre- and peri-conception periods of development modifies the hepatic proteome in the adult offspring
Genes & Nutrition, vol. 8, no. 2, pp. 181-190Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s12263-012-0314-6
Human fecal microbiota metabolize deoxynivalenol and deoxynivalenol-3-glucoside and may be responsible for urinary de-epoxy deoxynivalenol
Applied and Environmental Microbiology, vol. 79, no. 6, pp. 1821-1825Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/AEM.02987-12
Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of protein
Molecular Nutrition & Food Research, vol. 57, no. 3, pp. 523-535Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mnfr.201200594
Inter-organ proteomic analysis reveals insights into the molecular mechanisms underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in ob/ob mice
Proteomics, vol. 12, no. 3, pp. 461-476Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/pmic.201100312
Anti-platelet effects of olive oil extract: in vitro functional and proteomic studies
European Journal of Nutrition, vol. 50, no. 7, pp. 553-562Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00394-010-0162-3
High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health
The American Journal of Clinical Nutrition, vol. 93, no. 5, pp. 1062-1072Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3945/ajcn.110.002188
Impact of Obesity and Leptin on Protein Expression Profiles in Mouse Colon
Digestive Diseases and Sciences, vol. 56, no. 4, pp. 1028-1036Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s10620-010-1394-z
Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation
Journal of Proteome Research, vol. 9, no. 4, pp. 1941-1950Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1021/pr901103n
Intervention with fish oil, but not with docosahexaenoic acid, results in lower levels of hepatic soluble epoxide hydrolase with time in apoE knockout mice
British Journal of Nutrition, vol. 103, no. 1, pp. 16-24Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0007114509991450
Maternal diets deficient in folic acid and related methyl donors modify mechanisms associated with lipid metabolism in the fetal liver of the rat
British Journal of Nutrition, vol. 102, no. 10, pp. 1445-1452Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0007114509990389