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Professor Alison Avenell

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Professor Alison Avenell
Professor Alison Avenell
Professor Alison Avenell

Clinical Chair in Health Services Research

About
Email Address
a.avenell@abdn.ac.uk
Telephone Number
+44 (0)1224 438164
Office Address

Health Services Research Unit
3rd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Alison Avenell joined the Unit in 1998, as a Clinical Research Fellow. She was subsequently funded by the Chief Scientist Office (CSO) of the Scottish Government Health Directorates as a Clinical Research Fellow to undertake research in the MRC funded RECORD trial, which examined the effect of calcium and/or vitamin D supplementation in the secondary prevention of osteoporotic fractures. She also led the MAVIS trial which examined the effectiveness of vitamin and mineral supplementation in preventing infections in older people, and helped lead the SIGNET trial of glutamine and selenium supplementation in critical illness. She was a CSO funded Career Scientist and currently has a clinical chair in health services research and is an Honorary Consultant in Clinical Biochemistry, undertaking systematic reviews and randomised controlled trials of treatments for adult obesity, and under-nutrition in clinical practice.

Research

Current Research

Current projects

Completed projects

Publications

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  • Behavioural Interventions for Obese Adults with Additional Risk Factors for Morbidity: Systematic Review of Effects on Behaviour, Weight and Disease Risk Factors

    Dombrowski, S. U., Avenell, A., Sniehotta, F. F.
    Obesity Facts, vol. 3, no. 6, pp. 377-396
    Contributions to Journals: Articles

  • Systematic review of long-term lifestyle interventions to prevent weight gain and morbidity in adults

    Brown, T. J., Avenell, A., Edmunds, E., Moore, H., Whittaker, V., Avery, L., Summerbell, C., Ryan, M. E., Vale, L. D., PROGRESS team
    Obesity Reviews, vol. 10, no. 6, pp. 627-638
    Contributions to Journals: Articles

  • Systematic review and meta-analyses of studies of glutamine supplementation in haematopoietic stem cell transplantation

    Crowther, M., Avenell, A., Culligan, D. J.
    Bone Marrow Transplantation, vol. 44, no. 7, pp. 413-425
    Contributions to Journals: Articles

  • Vitamin D supplementation and type 2 diabetes: a substudy of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438)

    Avenell, A., Cook, J. A., MacLennan, G. S., McPherson, G. C., RECORD Trial Group
    Age and Ageing, vol. 38, no. 5, pp. 606-609
    Contributions to Journals: Articles

  • Symposium 4: Hot topics in parenteral nutrition Current evidence and ongoing trials on the use of glutamine in critically-ill patients and patients undergoing surgery

    Avenell, A.
    Proceedings of the Nutrition Society, vol. 68, no. 3, pp. 261-268
    Contributions to Journals: Articles

  • A case of apples and pears?

    Crowther, M., Vickers, M. A., Avenell, A.
    Blood, vol. 113, no. 24, pp. 6259-6260
    Contributions to Journals: Letters

  • Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis

    Avenell, A., Gillespie, W. J., Gillespie, L. D., O'Connell, D.
    Cochrane Database of Systematic Reviews, no. 2, CD000227
    Contributions to Journals: Articles

  • A Systematic Review of the Effectiveness of Group versus Individual Treatments for Adult Obesity

    Paul-Ebhohimhen, V. A., Avenell, A.
    Obesity Facts, vol. 2, no. 1, pp. 17-24
    Contributions to Journals: Articles

  • Protein and energy supplementation in elderly people at risk from malnutrition

    Milne, A. C., Potter, J., Vivanti, A., Avenell, A.
    Cochrane Database of Systematic Reviews, no. 2, CD003288
    Contributions to Journals: Articles

  • Radioiodine therapy (RAI) for Graves' disease (GD) and the effect on ophthalmopathy: a systematic review

    Acharya, S. H., Avenell, A., Philip, S., Burr, J., Bevan, J. S., Abraham, P.
    Clinical Endocrinology, vol. 69, no. 6, pp. 943-950
    Contributions to Journals: Articles

  • Calcium and vitamin D for prevention of osteoporotic fractures

    Freyschuss, B., Ljunggren, O., Saaf, M., Mellstrom, D., Avenell, A.
    Lancet, vol. 370, no. 9605, pp. 2098-2099
    Contributions to Journals: Letters

  • Randomised trial of glutamine and selenium supplemented parenteral nutrition for critically ill patients: Protocol version 9, 19 February 2007 known as SIGNET (Scottish Intensive Care Glutamine or seleNium Evaluative Trial)

    Andrews, P. J. D., Avenell, A., Noble, D. W., Campbell, M. K., Battison, C. G., Croal, B. L., Simpson, W. G., Norrie, J. D., Vale, L. D., Cook, J., De Verteuil, R., Milne, A. C., Trials Management Group
    Trials, vol. 8, 25
    Contributions to Journals: Articles

  • Vitamin D supplementation to prevent infections: a sub-study of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438)

    Avenell, A., Cook, J. A., MacLennan, G. S., MacPherson, G. C.
    Age and Ageing, vol. 36, no. 5, pp. 574-577
    Contributions to Journals: Letters

  • Response to Dr. Petrov [5]

    Koretz, R. L., Avenell, A., Lipman, T. O., Braunschweig, C. L., Milne, A. C.
    American journal of gastroenterology, vol. 102, no. 8, pp. 1829-1830
    Contributions to Journals: Letters

  • Is annual surveillance of all treated hypothyroid patients necessary?

    Viswanath, A. K., Avenell, A., Philip, S., Acharya, S. H., Maclennan, G., Dalziel, K., Pereira, O., Copland, S. A., Bevan, J. S., Abraham, P.
    BMC Endocrine Disorders, vol. 7, 4
    Contributions to Journals: Articles

  • A cost-utility analysis of multivitamin and multimineral supplements in men and women aged 65 years and over

    Kilonzo, M. M., Vale, L. D., Cook, J. A., Milne, A. C., Stephen, A. I., Avenell, A., MAVIS Trial Group
    Clinical Nutrition, vol. 26, no. 3, pp. 364-370
    Contributions to Journals: Articles

  • Effect of multivitamin and multimineral supplementation on cognitive function in men and women aged 65 years and over: A randomised controlled trial

    McNeill, G., Avenell, A., Campbell, M. K., Cook, J. A., Hannaford, P. C., Kilonzo, M. M., Milne, A. C., Ramsay, C. R., Seymour, D. G., Stephen, A. I., Vale, L. D.
    Nutrition Journal, vol. 6, 10
    Contributions to Journals: Articles

  • A lady with emerald green serum

    McNeilly, J. D., Avenell, A.
    CPD Bulletin Clinical Biochemistry, vol. 8, no. 3, pp. 94
    Contributions to Journals: Articles

  • Nutritional supplementation for hip fracture aftercare in older people

    Avenell, A., Handoll, H. H.
    Cochrane Database of Systematic Reviews, no. 4, CD001880
    Contributions to Journals: Articles

  • Meta-analysis: protein and energy supplementation in older people

    Milne, A. C., Avenell, A., Potter, J.
    Annals of Internal Medicine, vol. 144, pp. 37-48
    Contributions to Journals: Articles

  • A systematic review of multivitamin and multimineral supplementation for infection

    Stephen, A. I., Avenell, A.
    Journal of Human Nutrition and Dietetics, vol. 19, pp. 179-190
    Contributions to Journals: Articles

  • ABC of obesity: Management: Part I—Behaviour change, diet, and activity

    Avenell, A., Sattar, N., Lean, M.
    BMJ, vol. 333, no. 7571, pp. 740-743
    Contributions to Journals: Articles

  • Glutamine in critical care - current evidence from systematic reviews

    Avenell, A.
    Proceedings of the Nutrition Society, vol. 65, pp. 236-241
    Contributions to Journals: Articles

  • Glutamine-containing parental nutrition: another piece in the jigsaw?

    Noble, D., Avenell, A.
    Critical Care Medicine, vol. 34, no. 3, pp. 893-894
    Contributions to Journals: Articles

  • Improved food intake in older people

    Milne, A. C., Avenell, A., Potter, J.
    British Medical Journal, vol. 332, no. 7551, pp. 1165-1166
    Contributions to Journals: Articles

  • Adherence to dietary advice in weight-reduction drug trials

    Brown, T. J., Avenell, A.
    Lancet, vol. 366, no. 9500, pp. 1847-1848
    Contributions to Journals: Letters

  • Effect of multivitamin and multimineral supplements on morbidity from infections in older people (MAVIS trial): pragmatic, randomised, double blind, placebo controlled trial

    Avenell, A., Campbell, M. K., Cook, J. A., Hannaford, P. C., Kilonzo, M. M., McNeill, G., Milne, A. C., Ramsay, C. R., Seymour, D. G., Stephen, A. I., Vale, L. D., Writing Group on the MAVIS trial
    British Medical Journal, vol. 331, no. 7512, pp. 324-329
    Contributions to Journals: Articles

  • Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial

    Grant, A. M., Anderson, F. H., Avenell, A., Campbell, M. K., Cooper, C., Donaldson, C., Francis, R., Gillespie, W. J., Robinson, C. M., Torgerson, D. J., Wallace, W. A., RECORD Trial Group
    The Lancet, vol. 365, no. 9471, pp. 1621-1628
    Contributions to Journals: Articles

  • Long-term non-pharmacological weight loss interventions for adults with type 2 diabetes mellitus

    Norris, S. L., Zhang, X., Avenell, A., Gregg, E., Brown, T., Schmid, C. H., Lau, J.
    Cochrane Database of Systematic Reviews, vol. 2010, no. 1, CD004095
    Contributions to Journals: Review articles

  • Nutritional supplementation for hip fracture aftercare in older people

    Avenell, A., Handoll, H.
    Cochrane Database of Systematic Reviews, no. 2, CD001880
    Contributions to Journals: Articles

  • A systematic review of drug therapy for Graves' hypertension

    Abraham, P., Avenell, A., Watson, W. A., Bevan, J. S.
    European Journal of Endocrinology, vol. 153, pp. 489-498
    Contributions to Journals: Articles

  • Antithyroid drug regimen for treating Graves' hyperthyroidism

    Abraham, P., Avenell, A., Watson, W. A., Park, C. M., Bevan, J. S.
    Cochrane Database of Systematic Reviews, no. 2, CD003420
    Contributions to Journals: Articles

  • Effects of intentional weight loss in obese population with respect to all cause mortality: A Systematic review.

    Poobalan, A., Aucott, L., Smith, W. C., Avenell, A., Jung, R., Broom, J., Grant, A.
    14th European Congress on Obesity.
    Contributions to Conferences: Posters

  • Effects of weight loss in overweight/obese individual and long-term hypertension outcomes - A systematic review.

    Aucott, L. S., Poobalan, A. S., Smith, W. C. S., Avenell, A., Jung, R., Broom, J.
    Hypertension, vol. 45, pp. 1035-1041
    Contributions to Journals: Articles

  • Long-term effectiveness of weight-loss interventions in adults with pre-diabetes: a review

    Norris, S. L., Zhang, X., Avenell, A., Gregg, E., Bowman, B., Schmidt, C., Lau, J.
    American Journal of Preventive Medicine, vol. 28, no. 1, pp. 126-139
    Contributions to Journals: Articles

  • Long-term non-pharmacological weight loss interventions for adults with prediabetes.

    Norris, S. L., Zhang, X., Avenell, A., Gregg, E., Schmidt, C., Lau, J.
    Cochrane Database of Systematic Reviews, no. 2
    Contributions to Journals: Articles

  • Long-term non-pharmacological weight loss interventions for adults with type 2 diabetes.

    Norris, S. L., Zhang, X., Avenell, A., Gregg, E., Brown, T. J., Schmidt, C., Lau, J.
    Cochrane Database of Systematic Reviews, no. 2, CD004095
    Contributions to Journals: Articles

  • Oral protein and energy supplementation in older people: a systematic review of randomized trials.

    Milne, A. C., Avenell, A., Potter, J.
    Nestlé Nutrition workshop series. Clinical & performance programme, vol. 10, pp. 103-120; discussion 120-125
    Contributions to Journals: Review articles

  • Oral protein and energy supplementation in older people: a systematic review of randomised trials

    Milne, A. C., Avenell, A., Potter, J.
    Nestle Nutrition Series, vol. 10, pp. 103-125
    Contributions to Journals: Articles

  • Pharmacotherapy for weight loss in adults with type 2 diabetes.

    Norris, S. L., Zhang, X., Avenell, A., Gregg, E., Schmidt, C., Lau, J.
    Cochrane Database of Systematic Reviews, no. 1
    Contributions to Journals: Articles

  • Protein and energy supplementation in elderly people at risk from malnutrition

    Milne, A. C., Potter, J., Avenell, A.
    Cochrane Database of Systematic Reviews, no. 1
    Contributions to Journals: Articles

  • Routine oral nutritional supplementation for stroke patients in hospital (FOOD): a multicentre randomised controlled trial.

    Milne, A. C., Avenell, A., Grant, A. M., The FOOD Trial Collaboration
    The Lancet, vol. 365, no. 9461, pp. 755-763
    Contributions to Journals: Articles

  • Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement

    Avenell, A., Broom, J., Brown, T. J., Poobalan, A. S., Aucott, L. S., Stearns, S. C., Smith, W. C. S., Jung, R. T., Campbell, M. K., Grant, A. M.
    Health Technology Assessment, vol. 8, no. 21, pp. 1-182
    Contributions to Journals: Articles

  • Medical versus surgical interventions for open angle glaucoma

    Burr, J., Azuara-Blanco, A., Avenell, A.
    Cochrane Database of Systematic Reviews, no. 2, CD004399
    Contributions to Journals: Articles

  • Effects of weight loss in overweight/obese individuals and long-term lipid outcomes: a systematic review

    Poobalan, A. S., Aucott, L. S., Smith, W., Avenell, A., Jung, R., Broom, J., Grant, A. M.
    Obesity Reviews, vol. 5, no. 1, pp. 43-50
    Contributions to Journals: Articles

  • Nutritional supplementation for hip fracture aftercare in the elderly

    Avenell, A., Handoll, H. H. G.
    Cochrane Database of Systematic Reviews, no. 1, CD001880
    Contributions to Journals: Articles

  • Antithyroid drug regimen for treating Grave's hyperthyroidism

    Abraham, P., Avenell, A., Watson, W. A., Park, C. M., Bevan, J. S.
    Cochrane Database of Systematic Reviews, no. 2
    Contributions to Journals: Articles

  • Efficacy of pharmacotherapy for weight loss for adults with type 2 diabetes mellitus: a meta-analysis

    Norris, S. L., Gregg, E., Avenell, A., Zhang, X., Lau, J., Schmidt, C.
    Archives of Internal Medicine, vol. 164, no. 13, pp. 1395-1404
    Contributions to Journals: Articles

  • Obesity - a review of current treatments

    Jung, R., Avenell, A.
    Journal of the Royal College of Physicians of Edinburgh, vol. 34, pp. 181-183
    Contributions to Journals: Articles

  • Selenium supplementation for critically ill adults.

    Avenell, A., Noble, D. W., Barr, J., Engelhardt, T.
    Cochrane database of systematic reviews (Online), no. 4, pp. CD003703
    Contributions to Journals: Review articles
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