This is a past event
Dr Holly Spence is a Post-doctoral Research Fellow at the University of Aberdeen whose research focuses on the physical biology of neurodegenerative diseases including amyotrophic lateral sclerosis. Holly completed her PhD in Medical Sciences at the University of Aberdeen investigating the role of brain iron in age-related cognitive decline and exploring the relationships between brain iron and blood markers of iron and inflammation. Having moved to the Gregory Lab within the University of Aberdeen for a post-doc, her primary research interest lies in improving our understanding of the role of heavy metals in neurodegenerative processes including ferroptosis using a disease agnostic approach with the aim of improving symptom burden in patients.
Holly will discuss the findings from a supervised machine learning analysis with random forest classification on a cohort of 326 individuals to determine predictors of cognitive performance. 457 features were assessed including brain imaging measures of volume and iron deposition, blood iron and inflammation markers, deprivation indicators and atmospheric pollution exposure.
- Speaker
- Dr Holly Spence
- Venue
- 115, Health Sciences Building and TEAMS
- Contact
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Please email achds@abdn.ac.uk if you would like the TEAMS link to join remotely.