BSc MSc PhD MIPEM
Honorary Professor
- About
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- Email Address
- r.staff@abdn.ac.uk
- Office Address
Nuclear Medicine ARI Foresterhill Aberdeen AB25 2ZD
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Roger Staff was born in London and studied physics at UEA. He moved to Aberdeen in 1988 and completed his PhD in medical physics in 1994. He has worked for the NHS since 1991 and currently leads the clinical physics imaging team at NHS-Grampian. His other interests include Intelligence and social mobility.
- Research
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Research Overview
(Since 1999) founding member of the Aberdeen 1921 & 1936 birth cohort study group with three critical responsibilities for (1) hypothesis generation and hypothesis testing; (2) brain imaging and image analysis; (3) Advance data modelling of complex databases; (Since 2003 with Taurx) the imaging the effects tau aggregation inhibition and the use of surrogate imaging measures in drug development; (Since 2008) the development of structural and temporal (fMRI) complexity measures for use in ageing and neurodegenerative disease; (Since 2012) The prognostic value of automated analysis of sequential retinal images in diabetic retinopathy. The use of external quality assurance programs in diabetic retinopathy.
- Publications
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Page 2 of 4 Results 26 to 50 of 90
Klotho, APOEε4, cognitive ability, brain size, atrophy and survival: A study in the Aberdeen Birth Cohort of 1936
Neurobiology of Aging, vol. 55, pp. 91-98Contributions to Journals: ArticlesSexual dimorphism in changes of cortical complexity associated with cognitive decline in late life
Alzheimer's Research UKContributions to Conferences: AbstractsA brain imaging repository of normal structural MRI across the life course: Brain Images of Normal Subjects (BRAINS)
Neuroimage, vol. 144, no. Part B, pp. 299–304Contributions to Journals: ArticlesDistinct anatomical subtypes of behavioural variant frontotemporal dementia and involvement of intrinsic brain networks: a clustering study
Alzheimer Research UK (2017)Contributions to Conferences: AbstractsEfficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial
The Lancet, vol. 388, no. 10062, pp. 2873-2884Contributions to Journals: ArticlesLate-life deficits in cognitive, physical and emotional functions, childhood intelligence and occupational profile: a life-course examination of the Aberdeen 1936 Birth Cohort (ABC1936)
Age and Ageing, vol. 45, no. 4, pp. 486-493Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ageing/afw061
Brain hyperintensity location determines outcome in the triad of impaired cognition, physical health and depressive symptoms: A cohort study in late life
Archives of Gerontology and Geriatrics, vol. 63, pp. 49-54Contributions to Journals: ArticlesCerebral correlates of cognitive reserve
Psychiatry Research, vol. 247, pp. 65-70Contributions to Journals: ArticlesNeural correlates of cognitive and behavioural impairments in behavioural variant of frontotemporal dementia: A voxel based morphometry analysis
SINAPSE Annual Scientific Meeting (2016)Contributions to Conferences: AbstractsQUALITY ASSURANCE IN DIABETIC RETINAL SCREENING IN SOUTH AFRICA: A BASELINE AND FOLLOW-UP STUDY
26th Meeting of the European Association for the Study of Diabetes Eye Complications Study Group (EASDec), pp. E102-E102Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.5301/ejo.5000799
Phenothiazine compounds for treating mild cognitive impairment
Patents: PatentsFuzzy approximate entropy analysis of resting state fMRI signal complexity across the adult life span
Medical Engineering & Physics, vol. 37, no. 11, pp. 1082-1090Contributions to Journals: ArticlesA longitudinal study of cognitive and hippocampal ageing in late life
British Neuroscience Association, 2015 Festival of NeuroscienceContributions to Conferences: AbstractsMapping the cortical complexity and cognitive decline in late life
Alzheimer's research UK 2015Contributions to Conferences: AbstractsTau Aggregation Inhibitor Therapy: An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease
Journal of Alzheimer's Disease, vol. 44, no. 2, pp. 705-720Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3233/JAD-142874
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4205/1/fulltext.pdf
Structural brain complexity and cognitive decline in late life: A longitudinal study in the Aberdeen 1936 Birth Cohort
Neuroimage, vol. 100, pp. 558-563Contributions to Journals: ArticlesImproving the cost-effectiveness of photographic screening for diabetic macular oedema: a prospective, multi-centre, UK study
British Journal of Ophthalmology, vol. 98, no. 8, pp. 1042-1049Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bjophthalmol-2013-304338
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4265/1/ISMO_manuscript.doc
A longitudinal study of human brain complexity and cognitive decline in ageing
Organization of Human Brain Mapping meeting (OHBM)Contributions to Conferences: AbstractsNonlinear complexity analysis of brain FMRI signals in schizophrenia
PloS ONE, vol. 9, no. 5, e95146Contributions to Journals: ArticlesEarly Life Socioeconomic Circumstance and Late Life Brain Hyperintensities: A Population Based Cohort Study
PloS ONE, vol. 9, no. 2, e88969Contributions to Journals: ArticlesHomocysteine, antioxidant micronutrients and late onset dementia
European Journal of Nutrition, vol. 53, no. 1, pp. 277-285Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00394-013-0526-6
Depressive symptoms in late life and cerebrovascular disease: the importance of intelligence and lesion location
Depression and Anxiety, vol. 30, no. 1, pp. 77-84Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/da.22022
Genetic and environmental factors in late onset dementia: possible role for early parental death
International Journal of Geriatric Psychiatry, vol. 28, no. 1, pp. 75-81Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/gps.3792
Brain structural complexity and life course cognitive change
Neuroimage, vol. 61, no. 3, pp. 694-701Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.neuroimage.2012.03.088
Do brain image databanks support understanding of normal ageing brain structure?: A systematic review
European Radiology, vol. 22, no. 7, pp. 1385-1394Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00330-012-2392-7