Professor Mary MacLeod

BSc MBChB PhD FRCP

Personal Chair (Clinical)

Email Address: m.j.macleod@abdn.ac.uk
Telephone Number: +44 (0)1224 437842
School/Department: School of Medicine, Medical Sciences and Nutrition

Biography

Dr Macleod is a Clinical Pharmacologist with a personal chair (Teaching and Research) at the University of Aberdeen and honorary Consultant Physician within NHS Grampian. Her clinical work is largely in the area of acute stroke management, hypertension clinics and primary and secondary cardiovascular prevention. Current research interests include:

Novel imaging markers in stroke and small vessel disease using fast field cycling MRI

Using linked datasets to explore management of stroke including service organisation and secondary prevention

Interactions between stroke and other diseases (e.g. cancer)

Memberships and Affiliations

Internal Memberships: Chair, Clinical Studies Oversight Group
External Memberships: Chair of Scotland A and B Research Ethics Committees

Honorary Deputy Secretary, British and Irish Association of Stroke Physicians

Trustee SHARP (Scottish Heart and Arterial Disease Prevention)

Latest Publications

Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial
2024 - Published
Muir, K. W., Ford, G. A., Ford, I., Wardlaw, J. M., McConnachie, A., Greenlaw, N., Mair, G., Sprigg, N., Price, C. I., MacLeod, M. J., Dima, S., Venter, M., Zhang, L., O’Brien, E., Sanyal, R., Reid, J., Sztriha, L. K., Haider, S., Whiteley, W. N., Kennedy, J., Perry, R., Lakshmanan, S., Chakrabarti, A., Hassan, A., Marigold, R., Raghunathan, S., Sims, D., Bhandari, M., Wiggam, I., Rashed, K., Douglass, C., ATTEST-2 Investigators
The Lancet neurology, vol. 23, no. 11, pp. 1087-1096
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/S1474-4422(24)00377-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24433/1/Muir_etal_TLN_Tenecteplase_Versus_Alteplase_VoR.pdf
Field-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T
2024 - Published
Ross, J., Mallikourti, V., Maier, O., Guzman Gutierrez, G., Franko, E., Lurie, D., Broche, L., Macleod, M.
Radiology, vol. 312, no. 2, e232972
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1148/radiol.232972
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23512/3/Mallikourti_etal_R_Field_Cycling_MRI_For_VOR.pdf
- [ONLINE] View publication in Scopus
Acute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study
2024 - E-pub ahead of print
Sterling, K., MacLeod, M., Barber, M., Turner, M.
Cerebrovascular Diseases
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1159/000540371
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24484/1/Sterling_etal_CD_Acute_Care_Secondary_VoR.pdf
Randomised Trial of Tenecteplase versus Alteplase for Acute Stroke within 4.5h of onset: the second Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST-2)
2024 - Published
Muir, K., Ford, G., Ford, I., Wardlaw, J., McConnachie, A., Greenlaw, N., Price, C. I., Macleod, M., Dima, S., Venter, M., Zhang, L., O’Brien, E., Sanyal, R., Reid, J., Sztriha, L., Haider, S., Whiteley, W. N., Kennedy, J., Perry, R., Sekaran, L., Chakrabarti, A., Hassan, A., Marigold, R., Raghunathan, S., Sims, D., Bhandari, M., Douglass, C., ATTEST-2 Investigators
Working Papers: Preprint Papers
- [ONLINE] DOI: https://doi.org/10.2139/ssrn.4831843
- [ONLINE] https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4831843
Does following an “excellent” candidate in the Objective Structured Clinical Examination affect your checklist score?
2024 - Published
Brown, C. W., Watson, W., Macleod, M., Nath, M.
Journal of Applied Research in Higher Education, vol. 16, no. 3, pp. 891-903
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1108/JARHE-02-2023-0079
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/21557/1/Brown_etal_JARHE_Does_Following_an_Excellent_AAM.pdf

View My Publications

Teaching

Teaching Responsibilities

Year 5 MBChB OSCE coordinator

Situational Judgement Test lead

Year 1, 3 and 4 Clinical Pharmacology teaching

MSc Clinical Pharmacology: Pharmacovigilance, Medicines Management

Delivers teaching to MSc Cardiovascular and Diabetes, BSc Neurosciences, BSc Genetics

MRCP PACES examiner

Publications

Update

Biography

Memberships and Affiliations

Latest Publications

Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial

Field-Cycling MRI for Identifying Minor Ischemic Stroke Below 0.2 T

Acute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study

Randomised Trial of Tenecteplase versus Alteplase for Acute Stroke within 4.5h of onset: the second Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST-2)

Does following an “excellent” candidate in the Objective Structured Clinical Examination affect your checklist score?

Teaching Responsibilities

Poster Presentation - Design and validation of DNA pools in an ischaemic stroke population

Paraoxonase gene polymorphisms and haplotype analysis in a stroke population

Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population

ABCA1 gene polymoprhism and lipid profile in a Scottish population

Antihypertensive drug prescribing in Grampian

Timing of aspirin use in acute stroke and use of secondary prevention: stroke unit vs medical unit

Patient compliance in hypertension: role of illness perceptions and treatment beliefs

Genotype and haplotype analysis of ABCA1 gene in ischaemic stroke

Poster Presentation - Using the TOAST Criteria for Retrospective Classification of Ischemic Stroke Patients

Spatial channels of visual processing in cortical blindness

Hypertension in Diabetes: A Perspective from Clinical Pharmacology

Paraoxonase genes (PON1, 2 and 3) polymorphisms and ischaemic stroke in a Scottish population

Paraxonase 3 gene (PON3) polymorphism, ischaemic stroke and lipid profile in a Scottish population

Paraxonase genes (PON1, PON2 and PON3) polymorphisms and lipid profile in a Scottish population

Effects of mailed dissemination of the Royal College of Radiologists' guidelines on general practitioner referrals for radiography: a time series analysis

Genotype and Haplotype Analysis of Paraoxanase Genes (PON 1&2 ) and Ishcaemic Stroke in a Northern Scottish Population

Lack of association between apolipoprotein E genotype and ischaemic stroke in a Scottish population

Predicted impact of intravenous thrombolysis

Pharmacokinetic factors in the modern drug treatment of tuberculosis

No association between Glu/Asp polymorphism of NOS3 gene and ischemic stroke

Drug Treatment of Hypertension Complicating Diabetes Mellitus

Identification of a common low density lipoprotein receptor mutation (C163Y) in the west of Scotland

Renal artery stent placement in renal artery stenosis: Technical and early clinical results

Effect of renal-artery stenting on progression of renovascular renal failure

Sodium-lithium countertransport, sodium-hydrogen exchange and membrane microviscosity in patients with hyperlipidaemia

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