Bioinformatician
- About
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- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Louie van de Lagemaat joined the Centre for Genome-Enabled Biology and Medicine as a bioinformatician in October 2021. He completed his PhD in Genetics at the University of British Columbia, Canada in 2006. Subsequent positions focused on diverse subjects, including molecular neuroscience of the mammalian excitatory synapse and developmental and malignant haematopoiesis. He has used varied analytical methods such as linear and mixed effects models and has broad experience with short-read sequencing technologies including ChIP-seq, bulk and low-cell-count RNA-seq, mRNA splicing, ribosomal profiling (Ribo-seq), transcript methylation (meRIP-seq), poly-A tail length (tail-seq) and transcript half-life (SLAM-seq). He has also performed analysis of survival and loss of HLA allele heterozygosity in cancers.
- Research
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Research Specialisms
- Genomics
- Behavioural Biology
- Bioinformatics
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Publications
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Page 3 of 4 Results 21 to 30 of 35
Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder
PloS ONE, vol. 6, no. 4, e19011Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0019011
Characterization of the proteome, diseases and evolution of the human postsynaptic density.
Nature Neuroscience, vol. 14, pp. 19-21Contributions to Journals: ArticlesGenome variation and complexity in the autism spectrum
Neuron, vol. 67, no. 1, pp. 8-10Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.neuron.2010.06.026
Confirmed rare copy number variants implicate novel genes in schizophrenia
Biochemical Society Transactions, vol. 38, no. 2, pp. 445-451Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1042/BST0380445
Genome-wide assessments reveal extremely high levels of polymorphism of two active families of mouse endogenous retroviral elements
PLoS Genetics, vol. 4, no. 2, pp. e1000007Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pgen.1000007
Repeated recruitment of LTR retrotransposons as promoters by the anti-apoptotic locus NAIP during mammalian evolution
PLoS Genetics, vol. 3, no. 1, pp. e10Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pgen.0030010
Transcription of two human genes from a bidirectional endogenous retrovirus promoter
Gene, vol. 366, no. 2, pp. 335-342Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.gene.2005.09.003
Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line
PLoS Genetics, vol. 2, no. 1, pp. e2Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pgen.0020002
Multiple effects govern endogenous retrovirus survival patterns in human gene introns
Genome Biology, vol. 7, no. 9, pp. R86Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/gb-2006-7-9-r86
Endogenous retrovirus long terminal repeats as ready-to-use mobile promoters: the case of primate beta3GAL-T5
Gene, vol. 364, pp. 2-12Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.gene.2005.05.045