Professor Graeme MacLennan | People | The University of Aberdeen

Professor Graeme MacLennan

Director (CHaRT)

Email Address: g.maclennan@abdn.ac.uk
Telephone Number: +44 (0)1224 438147
Office Address: Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD
School/Department: School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.

Qualifications

BSc Mathematics
1997 - University of Aberdeen
MSc Applied Statistics
2004 - Sheffield Hallam University

Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).

Research on making trials more efficient, collaborating with Trial Forge.

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT)
2019 - Published
Martin, K. R., Bachmair, E., Aucott, L., Dures, E., Emsley, R., Gray, S. R., Hewlett, S., Kumar, V., Lovell, K., Macfarlane, G. J., MacLennan, G., McNamee, P., Norrie, J., Paul, L., Ralston, S., Siebert, S., Wearden, A., White, P. D., Basu, N.
BMJ Open, vol. 9, no. 1, e026793
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2018-026793
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11860/1/Protocol_for_a_multicentre_randomised_controlled_parallel_group_trial.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation
2018 - Published
Avenell, A., Robertson, C., Skea, Z., Jacobsen, E., Boyers, D., Cooper, D., Aceves-Martins, M., Retat, L., Fraser, C., Aveyard, P., Stewart, F., MacLennan, G., Webber, L., Corbould, E., Xu, B., Jaccard, A., Boyle, B., Duncan, E., Shimonovich, M., de Bruin, M.
Health Technology Assessment, vol. 22, no. 68, pp. 1-286
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta22680
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11603/2/Avenell_etal_HTA_Bariatric_Surgery_Lifestyle_VOR.pdf
- [ONLINE] Corrigendum
Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation
2018 - Published
Brazzelli, M., Hernández, R., Sharma, P., Robertson, C., Shimonovich, M., MacLennan, G., Fraser, C., Jamieson, R., Vallabhaneni, S. R.
Health Technology Assessment, vol. 22, no. 72, pp. 1-220
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta22720
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11881/1/3021699.pdf
DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial
2018 - Published
Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C., MacLennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., Vale, L. D.
BMJ, vol. 363, k3750
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmj.k3750
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11672/1/bmj.k3750.full.pdf
- [ONLINE] View publication in Scopus
DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial
2018 - Published
Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C., Maclennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., Vale, L. D.
Trials, vol. 19, 606
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-018-2884-0
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11519/1/DELTA2_guidance_on_choosing_the_target_difference_and_undertaking_and_reporting_the_sample_size_calculation_for_a_randomised_controlled_trial.pdf
- [ONLINE] View publication in Scopus
COMPARISON OF NINE SURGICAL TREATMENTS FOR WOMEN WITH STRESS URINARY INCONTINENCE: A COST-EFFECTIVENESS AND VALUE OF INFORMATION ANALYSIS
2018 - Published
Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S. A., Ternent, L., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L., Craig, D.
11th Annual European UroGynaecological Association Congress
Contributions to Conferences: Abstracts
- [ONLINE] https://www.eugaoffice.org/wp-content/uploads/2021/02/11th_EUGA_Congress_2018-abstract_book.pdf
A Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence
2018 - Published
Javanbakht, M., Moloney, E., Craig, D., Brazzelli, M., Wallace, S., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L.
ICS 2018
Contributions to Conferences: Abstracts
Partial factorial trials: comparing methods for statistical analysis and economic evaluation
2018 - Published
Dakin, H. A., Gray, A. M., MacLennan, G. S., Morris, R. W., Murray, D. W.
Trials, vol. 19, 442
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-018-2818-x
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10986/1/Partial_factorial_trials.pdf
Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial
2018 - Published
Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., Norrie, J., Hudson, J., Bowe, S. E., French, P., Byrne, R., Syrett, S., Dudley, R., McLeod, H. J., Griffiths, H., Barnes, T. R. E., Davies, L., Kingdon, D., FOCUS trial group
The lancet. Psychiatry, vol. 5, no. 8, pp. 633-643
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/S2215-0366(18)30184-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10891/2/Morrison_etal_TLP_Cognitive_Behavioural_Therapy_VOR.pdf
Treatment of Advanced Glaucoma Study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma—study protocol
2018 - Published
King, A. J., Fernie, G., Azuara-Blanco, A., Burr, J. M., Garway-Heath, T., Sparrow, J. M., Vale, L., Hudson, J., MacLennan, G., McDonald, A. M., Barton, K., Norrie, J.
British Journal of Ophthalmology, vol. 102, no. 7, pp. 922-928
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bjophthalmol-2017-310902
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9524/3/Treatment_of_Advanced_Glaucoma_Study.pdf
A Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence
2018 - Published
Javanbakht, M., Moloney, E., Craig, D., Brazzelli, M., Wallace, S., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L.
Health Technology Assessment international 2018 Annual Meeting
Contributions to Conferences: Abstracts
TISU: Extracorporeal shockwave lithotripsy, as first treatment option, compared with direct progression to ureteroscopic treatment, for ureteric stones: study protocol for a randomised controlled trial
2018 - Published
McClinton, S., Cameron, S., Starr, K., Thomas, R., MacLennan, G., McDonald, A., Lam, T., N’Dow, J., Kilonzo, M., Pickard, R., Anson, K., Keeley, F., Burgess, N., Clark, C. T., MacLennan, S., Norrie, J., TISU Study Group
Trials, vol. 19, no. 1, pp. 1-11
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-018-2652-1
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10489/1/McClinton_et_al_2018_Trials.pdf
Cancer and vitamin D supplementation: a systematic review and meta-analysis
2018 - Published
Goulao, B., Stewart, F., Ford, J. A., MacLennan, G., Avenell, A.
The American Journal of Clinical Nutrition, vol. 107, no. 4, pp. 652-663
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1093/ajcn/nqx047
- [ONLINE] http://nutrition.org/publications/guidelines-and-policies/permissions/
Instrumental variable methods for a binary outcome were used to informatively address non-compliance in a randomised trial in surgery
2018 - Published
Cook, J. A., Maclennan, G. S., Palmer, T., Lois, N., Emsley, R.
Journal of Clinical Epidemiology, vol. 96, pp. 126-132
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.jclinepi.2017.11.011
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10185/1/Instrumental_variable_methods_for_a_binary_outcome_were_used_to_informatively_address_noncompliance_in_a_randomized_trial_in_surgery.pdf
The split-plot design was useful for evaluating complex, multi-level interventions but there is need for improvement in its design and report
2018 - Published
Goulão, B., MacLennan, G., Ramsay, C.
Journal of Clinical Epidemiology, vol. 96, pp. 120-125
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.jclinepi.2017.10.019
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/11390/1/The_split_plot_design_was_useful_for_evaluating_complex_multi_level_interventions_but_there_is_need_for_improvement_in_its_design_and_report.pdf
Systematic Techniques to Enhance rEtention in Randomised controlled trials: the STEER study protocol
2018 - Published
Gillies, K., Bower, P., Elliott, J., MacLennan, G., Newlands, R. S. N., Ogden, M., Treweek, S. P., Wells, M., Witham, M. D., Young, B., Francis, J. J.
Trials, vol. 19, 197
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-018-2572-0
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10396/1/Systematic_Techniques_to_Enhance_rEtention_in_Randomised_controlled_trials_the_STEER_study_protocol.pdf
How to resolve discrepancies when findings from randomized controlled trials and meta-analyses disagree?
2018 - Published
Sylvester, R., Canfield, S. E., Lam, T., Marconi, L., MacLennan, S., Yuan, Y., MacLennan, G., Norrie, J., Omar, M. I., Bruins, H. M., Hernández, V., Plass, K., Van Poppel, H., N'Dow, J.
33rd Annual EAU Congress 2018
Contributions to Conferences: Posters
- [ONLINE] https://urosource.uroweb.org/resource-centres/eau18/6024/abstract
Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): Study protocol for a randomised controlled trial
2018 - Published
Constable, L., Cotterill, N., Cooper, D., Glazener, C., Drake, M. J., Forrest, M., Harding, C., Kilonzo, M., MacLennan, G., McCormack, K., McDonald, A., Mundy, A., Norrie, J., Pickard, R., Ramsay, C., Smith, R., Wileman, S., Abrams, P., The MASTER Study Group
Trials, vol. 19, pp. 1-17
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-018-2501-2
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10149/1/Trials.pdf
- [ONLINE] View publication in Scopus
Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease and cancer: a systematic review and meta-analysis
2017 - Published
Ma, C., Avenell, A., Bolland, M., Hudson, J., Stewart, F., Robertson, C., Sharma, P., Fraser, C., MacLennan, G.
BMJ, vol. 359, j4849
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmj.j4849
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9613/1/Effects_of_weight_loss_interventions_for_adults_who_are_obese_.pdf
Bayesian clinical trial designs: Another option for trauma trials?
2017 - Published
Jansen, J. O., Pallmann, P., MacLennan, G., Campbell, M. K., UK-REBOA Trial Investigators
The journal of trauma and acute care surgery, vol. 83, no. 4, pp. 736-741
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1097/TA.0000000000001638
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9434/1/Bayesian_clinical_trial_designs_Another_option.26_1_.pdf
THISTLE: trial of hands-on Interprofessional simulation training for local emergencies: a research protocol for a stepped-wedge clustered randomised controlled trial
2017 - Published
Lenguerrand, E., Winter, C., Innes, K., MacLennan, G., Siassakos, D., Lynch, P., Cameron, A., Crofts, J., McDonald, A., McCormack, K., Forrest, M., Norrie, J., Bhattacharya, S., Draycott, T., Thistle group
BMC Pregnancy and Childbirth, vol. 17, 294
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s12884-017-1455-9
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9347/1/THISTLE_trial_of_hands_on_Interprofessional.pdf
The SIMS trial: adjustable anchored single-incision mini-slings versus standard tension-free midurethral slings in the surgical management of female stress urinary incontinence. A study protocol for a pragmatic, multicentre, non-inferiority randomised controlled trial
2017 - Published
Abdel-Fattah, M., Maclennan, G., Kilonzo, M., Assassa, R. P., McCormack, K., Davidson, T., McDonald, A., N'Dow, J., Wardle, J., Norrie, J.
BMJ Open, vol. 7, no. 8, pp. 1-18
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2016-015111
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9208/1/e015111.full.pdf
- [ONLINE] View publication in Scopus
Long-Term Randomized Trial of Intensive Versus Symptomatic Management in Paget's Disease of Bone: The PRISM-EZ Study
2017 - Published
Tan, A., Goodman, K., Walker, A., Hudson, J., MacLennan, G. S., Selby, P. L., Fraser, W. D., Ralston, S. H., PRISM-EZ Trial Group
Journal of Bone and Mineral Research, vol. 32, no. 6, pp. 1165-1173
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1002/jbmr.3066
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10009/1/PRISM_EZ_.docx
Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree
2017 - Published
Sylvester, R. J., Canfield, S. E., Lam, T. B. L., Marconi, L., MacLennan, S., Yuan, Y., MacLennan, G., Norrie, J., Omar, M. I., Bruins, H. M., Hernandez, V., Plass, K., Van Poppel, H., N'Dow, J.
European Urology, vol. 71, no. 5, pp. 811-819
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.eururo.2016.11.023
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9668/1/EURUROL_D_16_01016R2.pdf
The BJUI's clinical trials initiative
2017 - Published
Davis, J. W., MacLennan, G.
BJU International, vol. 119, no. 4, pp. 503
Contributions to Journals: Editorials
- [ONLINE] DOI: https://doi.org/10.1111/bju.13837
- [ONLINE] View publication in Scopus
Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROSPECT)
2017 - Published
Glazener, C. M. A., Breeman, S., Elders, A., Hemming, C., Cooper, K. G., Freeman, R. M., Smith, A. R. B., Reid, F., Hagen, S., Montgomery, I., Kilonzo, M., Boyers, D., McDonald, A., McPherson, G., MacLennan, G., Norrie, J., PROSPECT study group
The Lancet, vol. 389, no. 10067, pp. 381–392
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(16)31596-3
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8285/3/mesh_graft_or_standard_repair_for_women_having_primary_transvaginal_anterior_or_posterior_compartment_prolapse_surgery.pdf
The curious case of an internal pilot in a multicentre randomised trial-time for a rethink?
2016 - Published
Cook, J. A., Beard, D. J., Cook, J. R., MacLennan, G. S.
Pilot & Feasibility Studies, vol. 2, 73
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s40814-016-0113-8
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8065/1/Cook_PilotandFeasibilityStudies.pdf
Clinical effectiveness and cost-effectiveness of surgical options for the management of anterior and/or posterior vaginal wall prolapse: two randomised controlled trials within a comprehensive cohort study - results from the PROSPECT Study
2016 - Published
Glazener, C., Breeman, S., Elders, A., Hemming, C., Cooper, K., Freeman, R., Smith, A., Hagen, S., Montgomery, I., Kilonzo, M., Boyers, D., McDonald, A., McPherson, G., MacLennan, G., Norrie, J.
Health Technology Assessment, vol. 20, no. 95, pp. 1-452
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta20950
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8494/1/HTA.pdf
Reporting and dealing with missing quality of life data in RCTs: has the picture changed in the last decade?
2016 - Published
Fielding, S., Ogbuagu, A., Sivasubramaniam, S., MacLennan, G., Ramsay, C. R.
Quality of Life Research, vol. 25, no. 12, pp. 2977-2983
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1007/s11136-016-1411-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/7694/1/art_3A10.1007_2Fs11136_016_1411_6.pdf
The eEffectiveness and cost-effectiveness of Surgical Treatments for womEn with stRess urinary incontinence:: an evidence synthesis (ESTER)
2016 - Published
Brazzelli, M., Craig, D., Imamura, M., Wallace, S., MacLennan, G., Hudson, J., Saraswat, L., Omar, M. I., Montgomery, I.
Contributions to Journals: Registered Reports
- [ONLINE] https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42016049339
Breast pumps as an incentive for breastfeeding: a mixed methods study of acceptability
2016 - Published
Crossland, N., Thomson, G., Morgan, H., MacLennan, G., Campbell, M., Dykes, F., Hoddinott, P.
Maternal and Child Nutrition, vol. 12, no. 4, pp. 726-739
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1111/mcn.12346
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/7341/3/Crossland_et_al_2016_Maternal_Child_Nutrition.pdf
Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial
2016 - Published
Pyle, M., Norrie, J., Schwannauer, M., Kingdon, D., Gumley, A., Turkington, D., Byrne, R., Syrett, S., MacLennan, G., Dudley, R., McLeod, H. J., Griffiths, H., Bowe, S., Barnes, T. R. E., French, P., Hutton, P., Davies, L., Morrison, A. P.
BMC Psychiatry, vol. 16, pp. 1-12
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s12888-016-0983-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/7496/1/art_3A10.1186_2Fs12888_016_0983_6.pdf
A protocol for a systematic review of non-randomised evaluations of strategies to improve participant recruitment to randomised controlled trials
2016 - Published
Gardner, H. R., Fraser, C., MacLennan, G., Treweek, S.
Systematic reviews , vol. 5, 131
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13643-016-0308-3
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16035/1/Gardener_Etal_SR_Protocol_systematic_review_VOR.pdf
Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review
2016 - Published
Cruickshank, M., Henderson, L., MacLennan, G., Fraser, C., Campbell, M., Blackwood, B., Gordon, A., Brazzelli, M.
Health Technology Assessment, vol. 20, no. 25, pp. 0-120
Contributions to Journals: Literature Reviews
- [ONLINE] DOI: https://doi.org/10.3310/hta20250
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5856/1/FullReport_hta20250.pdf
Behavioural recovery after treatment for varicose veins
2016 - Published
Cotton, S. C., MacLennan, G., Brittenden, J., Prior, M., Francis, J.
British Journal of Surgery, vol. 103, no. 4, pp. 374-381
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1002/bjs.10081
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5616/1/Cotton_et_al_2016_British_Journal_of_Surgery.pdf
The ethics of future trials: qualitative analysis of physicians' decision making
2016 - Published
Webster, F., Weijer, C., Todd, L., Grimshaw, J. M., Marshall, A. P., Cook, D., MacLennan, G., Cuthbertson, B. H., Francis, J. J., SuDDICU International Study Group
Trials, vol. 17, pp. 1-8
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-015-1137-8
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5905/1/art_3A10.1186_2Fs13063_015_1137_8.pdf
Mindfulness-Based Stress Reduction for Veterans With PTSD
2016 - Published
Goulao, B., MacLennan, G. S.
JAMA, vol. 315, no. 1, pp. 87-88
Contributions to Journals: Letters
- [ONLINE] DOI: https://doi.org/10.1001/jama.2015.15170
Kurzdarstellung aktueller publikationen: Begünstigt eine muskelrelaxierende therapie den uretersteinabgang?
2016 - Published
Pickard, R., Starr, K., MacLennan, G., Lam, T., Thomas, R., Burr, J., McPherson, G., McDonald, A., Anson, K., N'Dow, J., Burgess, N., Clark, T., Kilonzo, M., Gillies, K., Shearer, K., Boachie, C., Cameron, S., Norrie, J., McClinton, S.
Nieren- und Hochdruckkrankheiten, vol. 45, no. 1, pp. 38
Contributions to Journals: Articles
- [ONLINE] View publication in Scopus
Open urethroplasty versus endoscopic urethrotomy - clarifying the management of men with recurrent urethral stricture (the OPEN trial): study protocol for a randomised controlled trial
2015 - Published
Stephenson, R., Carnell, S., Johnson, N., Brown, R., Wilkinson, J., Mundy, A., Payne, S., Watkin, N., N'Dow, J., Sinclair, A., Rees, R., Barclay, S., Cook, J. A., Goulao, B., MacLennan, G., McPherson, G., Jackson, M., Rapley, T., Shen, J., Vale, L., Norrie, J., McColl, E., Pickard, R.
Trials, vol. 16, 600
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-015-1120-4
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5403/1/s13063_015_1120_4.pdf
Perspectives on financial incentives to health service providers for increasing breastfeeding and smoking quit rates during pregnancy: a mixed methods study
2015 - Published
Hoddinott, P., Thomson, G., Morgan, H., Crossland, N., MacLennan, G. S., Dykes, F., Stewart, F., Bauld, L., Campbell, M. K.
Maternal and Child Nutrition, vol. 11, no. Supplement S2, pp. 113
Contributions to Journals: Abstracts
- [ONLINE] DOI: https://doi.org/10.1111/mcn.12238
Perspectives on financial incentives to health service providers for increasing breastfeeding and smoking quit rates during pregnancy: a mixed methods study
2015 - Published
Hoddinott, P., Thomson, G., Morgan, H., Crossland, N., MacLennan, G., Dykes, F., Stewart, F., Bauld, L., Campbell, M. K.
BMJ Open, vol. 5, no. 11, e008492
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2015-008492
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5282/3/BMJ_Open_2015_Hoddinott_.pdf
Ureteric colic and clinical evidence - Authors' reply
2015 - Published
Pickard, R., MacLennan, G., Norrie, J., McClinton, S.
The Lancet, vol. 386, no. 10006, pp. 1823
Contributions to Journals: Comments and Debates
- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(15)00764-3
Surgical management for localised penile cancer: [Cochrane Protocol]
2015 - Published
Imamura, M., MacLennan, S., Lam, T., Vint, R., Stewart, F., MacLennan, G., Omar, M. I., MacLennan, S., Griffiths, T. R. L., Watkin, N., Horenblas, S., Hakenberg, O. W., N'Dow, J., Summerton, D. J.
Contributions to Journals: Registered Reports
- [ONLINE] https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42015025638
Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre, placebo-controlled, randomised controlled trial and cost-effectiveness analysis of a calcium channel blocker (nifedipine) and an alpha-blocker (tamsulosin) (the SUSPEND trial)
2015 - Published
Pickard, R., Starr, K., MacLennan, G., Kilonzo, M., Lam, T., Thomas, R. E., Burr, J., Norrie, J., McPherson, G., McDonald, A., Shearer, K., Gillies, K., Anson, K., Boachie, C., N'Dow, J., Burgess, N., Clark, T., Cameron, S., McClinton, S.
Health Technology Assessment, vol. 19, no. 63, pp. 1-171
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta19630
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5166/1/FullReport_hta19630.pdf.crdownload
Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial
2015 - Published
Pickard, R., Starr, K., MacLennan, G., Lam, T. B. L., Thomas, R., Burr, J., McPherson, G., McDonald, A., Anson, K., N'Dow, J., Burgess, N., Clark, T., Kilonzo, M., Gillies, K., Shearer, K., Boachie, C., Cameron, S., Norrie, J., McClinton, S.
The Lancet, vol. 386, no. 9991, pp. 341-349
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(15)60933-3
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4641/3/1_s2.0_S0140673615609333_main.pdf
Ablative therapy for people with localised prostate cancer: a systematic review and economic evaluation
2015 - Published
Ramsay, C. R., Adewuyi, T. E., Gray, J., Hislop, J., Shirley, M. D., Jayakody, S., MacLennan, G., Fraser, C., MacLennan, S., Brazzelli, M., N'Dow, J., Pickard, R., Robertson, C., Rothnie, K., Rushton, S. P., Vale, L., Lam, T. B.
Health Technology Assessment, vol. 19, no. 49, pp. 1-524
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta19490
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4713/3/Ramsay_etal_HTA_Ablative_Therapy_For_VOR.pdf
A systematic review of the use of an expertise-based randomised controlled trial design
2015 - Published
Cook, J. A., Elders, A., Boachie, C., Bassinga, T., Fraser, C. M., Altman, D., Boutron, I., Ramsay, C. R., MacLennan, G. S.
Trials, vol. 16, 241
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1186/s13063-015-0739-5
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4683/1/Cook_2015.pdf
STOPPIT Baby Follow-Up Study: The Effect of Prophylactic Progesterone in Twin Pregnancy on Childhood Outcome
2015 - Published
McNamara, H. C., Wood, R., Chalmers, J., Marlow, N., Norrie, J., MacLennan, G., McPherson, G., Boachie, C., Norman, J. E.
PloS ONE, vol. 10, no. 4, e0122341
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0122341
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4461/1/PLOS_0122341.pdf
Benefits of incentives for breastfeeding and smoking cessation in pregnancy (BIBS): a mixed methods study to inform trial design
2015 - Published
Morgan, H., Hoddinott, P., Thomson, G., Crossland, N., Farrar, S., Yi, D., Hislop, J. M., Hall Moran, V., MacLennan, G. S., Dombrowski, S. U., Rothnie, K. J., Stewart, F., Bauld, L., Ludbrook, A., Dykes, F., Sniehotta, F. F., Tappin, D., Campbell, M. K.
Health Technology Assessment, vol. 19, no. 30, pp. 1-564
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta19300
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4578/2/Morgan_etal_HTA_Benefits_Of_Incentives_VOR.pdf
Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial
2015 - Published
Brittenden, J., Cotton, S. C., Elders, A., Tassie, E., Scotland, G., Ramsay, C. R., Norrie, J., Burr, J., Francis, J., Wileman, S., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., MacLennan, G., Prior, M., Bolsover, D., Campbell, M. K.
Health Technology Assessment, vol. 19, no. 27, pp. 1-342
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/hta19270
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4430/1/CLASS.pdf

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Current Research

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Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT)

Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation

Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation

DELTA 2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

COMPARISON OF NINE SURGICAL TREATMENTS FOR WOMEN WITH STRESS URINARY INCONTINENCE: A COST-EFFECTIVENESS AND VALUE OF INFORMATION ANALYSIS

A Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence

Partial factorial trials: comparing methods for statistical analysis and economic evaluation

Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial

Treatment of Advanced Glaucoma Study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma—study protocol

A Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence

TISU: Extracorporeal shockwave lithotripsy, as first treatment option, compared with direct progression to ureteroscopic treatment, for ureteric stones: study protocol for a randomised controlled trial

Cancer and vitamin D supplementation: a systematic review and meta-analysis

Instrumental variable methods for a binary outcome were used to informatively address non-compliance in a randomised trial in surgery

The split-plot design was useful for evaluating complex, multi-level interventions but there is need for improvement in its design and report

Systematic Techniques to Enhance rEtention in Randomised controlled trials: the STEER study protocol

How to resolve discrepancies when findings from randomized controlled trials and meta-analyses disagree?

Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): Study protocol for a randomised controlled trial

Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease and cancer: a systematic review and meta-analysis

Bayesian clinical trial designs: Another option for trauma trials?

THISTLE: trial of hands-on Interprofessional simulation training for local emergencies: a research protocol for a stepped-wedge clustered randomised controlled trial

The SIMS trial: adjustable anchored single-incision mini-slings versus standard tension-free midurethral slings in the surgical management of female stress urinary incontinence. A study protocol for a pragmatic, multicentre, non-inferiority randomised controlled trial

Long-Term Randomized Trial of Intensive Versus Symptomatic Management in Paget's Disease of Bone: The PRISM-EZ Study

Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree

The BJUI's clinical trials initiative

Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROSPECT)

The curious case of an internal pilot in a multicentre randomised trial-time for a rethink?

Clinical effectiveness and cost-effectiveness of surgical options for the management of anterior and/or posterior vaginal wall prolapse: two randomised controlled trials within a comprehensive cohort study - results from the PROSPECT Study

Reporting and dealing with missing quality of life data in RCTs: has the picture changed in the last decade?

The eEffectiveness and cost-effectiveness of Surgical Treatments for womEn with stRess urinary incontinence:: an evidence synthesis (ESTER)

Breast pumps as an incentive for breastfeeding: a mixed methods study of acceptability

Design and protocol for the Focusing on Clozapine Unresponsive Symptoms (FOCUS) trial: a randomised controlled trial

A protocol for a systematic review of non-randomised evaluations of strategies to improve participant recruitment to randomised controlled trials

Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

Behavioural recovery after treatment for varicose veins

The ethics of future trials: qualitative analysis of physicians' decision making

Mindfulness-Based Stress Reduction for Veterans With PTSD

Kurzdarstellung aktueller publikationen: Begünstigt eine muskelrelaxierende therapie den uretersteinabgang?

Open urethroplasty versus endoscopic urethrotomy - clarifying the management of men with recurrent urethral stricture (the OPEN trial): study protocol for a randomised controlled trial

Perspectives on financial incentives to health service providers for increasing breastfeeding and smoking quit rates during pregnancy: a mixed methods study

Perspectives on financial incentives to health service providers for increasing breastfeeding and smoking quit rates during pregnancy: a mixed methods study

Ureteric colic and clinical evidence - Authors' reply

Surgical management for localised penile cancer: [Cochrane Protocol]

Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre, placebo-controlled, randomised controlled trial and cost-effectiveness analysis of a calcium channel blocker (nifedipine) and an alpha-blocker (tamsulosin) (the SUSPEND trial)

Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial

Ablative therapy for people with localised prostate cancer: a systematic review and economic evaluation

A systematic review of the use of an expertise-based randomised controlled trial design

STOPPIT Baby Follow-Up Study: The Effect of Prophylactic Progesterone in Twin Pregnancy on Childhood Outcome

Benefits of incentives for breastfeeding and smoking cessation in pregnancy (BIBS): a mixed methods study to inform trial design

Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial

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Books and Reports

Chapters in Books, Reports and Conference Proceedings

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Contributions to Journals

DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial