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Professor Graeme MacLennan

Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

About
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge. 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • Vitamin D supplementation to prevent infections: a sub-study of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438)

    Avenell, A., Cook, J. A., MacLennan, G. S., MacPherson, G. C.
    Age and Ageing, vol. 36, no. 5, pp. 574-577
    Contributions to Journals: Letters

  • Applying psychological theories to evidence-based clinical practice: Identifying factors predictive of managing upper respiratory tract infections without antibiotics

    Eccles, M. P., Grimshaw, J. M., Johnston, M., Steen, N., Pitts, N. B., Thomas, R., Glidewell, E., Maclennan, G., Bonetti, D., Walker, A.
    Implementation Science, vol. 2, no. 26
    Contributions to Journals: Articles

  • The effects of mandatory prescribing of thiazides for newly treated, uncomplicated hypertension: interrupted time-series analysis

    Fretheim, A., Havelsrud, K., MacLennan, G., Kristoffersen, D. T., Oxman, A. D.
    PLoS Medicine, vol. 4, no. 7, e232
    Contributions to Journals: Articles

  • Is annual surveillance of all treated hypothyroid patients necessary?

    Viswanath, A. K., Avenell, A., Philip, S., Acharya, S. H., Maclennan, G., Dalziel, K., Pereira, O., Copland, S. A., Bevan, J. S., Abraham, P.
    BMC Endocrine Disorders, vol. 7, 4
    Contributions to Journals: Articles

  • Systematic review of economic evaluations and cost analyses of guideline implementation strategies

    Vale, L. D., Thomas, R. E., MacLennan, G. S., Grimshaw, J.
    European Journal of Health Economics, vol. 8, no. 2, pp. 111-121
    Contributions to Journals: Articles

  • Topical antimicrobials in combination with admission screening and barrier precautions to control endemic methicillin-resistant Staphylococcus aureus in an Intensive Care Unit

    Gould, I. M., MacKenzie, F. M., MacLennan, G., Pacitti, D., Watson, E. J., Noble, D.
    International Journal of Antimicrobial Agents, vol. 29, no. 5, pp. 536-543
    Contributions to Journals: Articles

  • Is the involvement of opinion leaders in the implementation of research findings a feasible strategy?

    Grimshaw, J. M., Eccles, M. P., Greener, J., Maclennan, G., Ibbotson, T., Kahan, J. P., Sullivan, F.
    Implementation Science, vol. 1, no. 1, 3
    Contributions to Journals: Articles

  • Applying psychological theory to evidence-based clinical practice: identifying factors predictive of taking intra-oral radiographs

    Bonetti, D. L., Pitts, N., Eccles, M., Grimshaw, J., Johnston, M., Steen, N., Glidewell, E., Thomas, R. E., MacLennan, G. S., Clarkson, J., Walker, A. E.
    Social Science & Medicine, vol. 63, no. 7, pp. 1889-1899
    Contributions to Journals: Articles

  • Accuracy of weight and height estimation in an intensive care unit: Implications for clinical practice and research

    Bloomfield, R., Steel, E., MacLennan, G. S., Noble, D. W.
    Critical Care Medicine, vol. 34, no. 8, pp. 2153-2157
    Contributions to Journals: Articles

  • Which surgical decisions should patients participate in and how?: Reflections on women's recollections of discussions about variants of hysterectomy

    Entwistle, V., Skea, Z., MacLennan, G., Williams, B., Bhattacharya, S.
    Social Science & Medicine, vol. 62, no. 2, pp. 499-509
    Contributions to Journals: Articles

  • Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement (BPE)

    Lourenco, T., Armstrong, N., N'Dow, J. M. O., Nabi, G., Deverill, M., Pickard, R., Vale, L. D., MacLennan, G. S., Fraser, C. M., McClinton, S., Wong, S., Coutts, A., Mowatt, G., Grant, A. M., BPE Study Group
    Unknown Publisher
    Books and Reports: Commissioned Reports

  • Methods of hysterectomy: should women have a say?

    Entwistle, V. A., MacLennan, G. S., Skea, Z. C., Bhattacharya, S., Williams, B.
    British Medical Journal, vol. 331, pp. 351-352
    Contributions to Journals: Letters

  • Effectiveness and efficiency of guideline dissemination and implementation strategies

    Grimshaw, J. M., Thomas, R. E., MacLennan, G., Fraser, C., Ramsay, C. R., Vale, L., Whitty, P., Eccles, M. P., Matowe, L., Shirran, L., Wensing, M., Dijkstra, R., Donaldson, C.
    International Journal of Technology Assessment in Health Care, vol. 21, no. 1
    Contributions to Journals: Articles

  • A randomised controlled trial of a tailored, multifaceted strategy to promote implementation of a clinical guideline on induced abortion care

    Foy, R., Penney, G., Grimshaw, J. M., Ramsay, C. R., Walker, A. E., MacLennan, G. S., Stearns, S. C., McKenzie, L., Glasier, A.
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 111, no. 7, pp. 726-733
    Contributions to Journals: Articles

  • Women's perceptions of decision-making about hysterectomy

    Skea, Z. C., Harry, V., Bhattacharya, S., Entwistle, V. A., Williams, B. S., MacLennan, G. S., Templeton, A. A.
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 111, no. 2, pp. 133-142
    Contributions to Journals: Articles

  • Effectiveness and efficiency of guideline dissemination and implementation strategies

    Thomas, R. E., MacLennan, G. S., Fraser, C. M., Ramsay, C. R., Vale, L. D., Whitty, P., Eccles, M. P., Matowe, L., Shirran, E. A., Wensing, M., Dijkstra, R., Donaldson, C.
    Health Technology Assessment, vol. 8, no. 6, pp. 1-352
    Contributions to Journals: Articles

  • Effectiveness of strategies to disseminate and implement clinical guidelines for the management of impacted and unerupted third molars in primary dental care, a cluster randomised controlled trial

    Bahrami, M., Deery, C., Clarkson, J. E., Pitts, N. B., Johnston, M., Ricketts, I., MacLennan, G., Nugent, Z. J., Tilley, C., Bonetti, D., Ramsay, C.
    British Dental Journal, vol. 197, pp. 691-696
    Contributions to Journals: Articles

  • Guidelines can improve process and outcomes of healthcare

    Thomas, R. E., Eccles, M., MacLennan, G. S., Fraser, C. M., Vale, L. D.
    Journal of the Royal College of Physicians of Edinburgh, vol. 34, pp. 76-77
    Contributions to Journals: Articles

  • Sample size calculator for cluster randomized trials

    Campbell, M. K., Thomson, S., Ramsay, C. R., MacLennan, G. S.
    Computers in Biology and Medicine, vol. 34, no. 2, pp. 113-125
    Contributions to Journals: Articles

  • Guideline dissemination and implementation strategies: a systematic review of effectiveness and efficiency

    Thomas, R. E., MacLennan, G. S., Fraser, C. M., Ramsay, C. R., Vale, L. D., Whitty, P., Eccles, M., Matowe, L., Shirran, E. A.
    Journal of Epidemiology and Community Health, vol. 57, no. 9 Suppl 1
    Contributions to Journals: Articles

  • Survival Data

    MacLennan, G. S.
    In: Key topics in clinical research (eds. Smith,F. G.;Smith,J. E.), BIOS, Oxford, pp. 155-163, 8 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Prevalence of honorary and ghost authorship in Cochrane reviews

    Mowatt, G., Shirran, E. A., Rennie, D., Flanagin, A., Yank, V., MacLennan, G. S., Gotzsche, P. C., Bero, L. A.
    JAMA, vol. 287, no. 21, pp. 2769-2771
    Contributions to Journals: Articles

  • Primary care guidelines on consultation practices: the effectiveness of computerized versus paper-based versions. A cluster randomized controlled trial among newly qualified primary care physicians

    Jousimaa, J., Makela, M., Kunnamo, I., MacLennan, G. S.
    International Journal of Technology Assessment in Health Care, vol. 18, no. 3, pp. 586-596
    Contributions to Journals: Articles

  • Attributes of clinical recommendations that influence changes in practice following audit and feedback

    Foy, R., MacLennan, G. S., Penney, G., Campbell, M. K., Grol, R.
    Journal of Clinical Epidemiology, vol. 55, no. 7, pp. 717-722
    Contributions to Journals: Articles
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