BSc MSc MRes PhD (Cantab.)
Advanced Research Fellow
- About
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- Email Address
- fergal.waldron@abdn.ac.uk
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
My research focuses on the roles of immunity, inflammation, and the gut-brain axis in ALS. I also work on biomarker developement in neurodegenerative disease but for ALS in particular. I am interested in heterogeneity, and early detection of disease, and my work involves a combination of experimental, molecular, histological, bioinformatics and meta-analytical approaches to answer fundamental questions in ALS research.
I obtained my PhD in Evolutionary Genetics from the University of Cambridge before undertaking postdoctoral work at the Institute of Evolutionary Biology at the University of Edinburgh.
Qualifications
- BSc Zoology2003 - National University of Ireland, Galway
- MRes Zoology2006 - National University of Ireland, Galway
- MSc Evolutionary Genetics and Genome Analysis2008 - University of Edinburgh
- PhD Evolutionary Genetics2013 - University of Cambridge
Internal Memberships
The Genetics Society
The Pathological Society of Great Britain and Ireland
Latest Publications
Integrating Transfer Learning and Attention Mechanisms for Accurate ALS Diagnosis and Cognitive Impairment Detection
Working Papers: Discussion Papers- [ONLINE] DOI: https://doi.org/10.1101/2024.09.22.24313406
Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis
Brain Pathology, e13287Contributions to Journals: ArticlesUnderstanding the influence of altered lipid metabolism on TDP-43 pathology:: a protocol for a systematic review and meta-analysis v1
protocols.io.Other Contributions: Other Contributions- [ONLINE] DOI: https://doi.org/10.17504/protocols.io.8epv5xk75g1b/v1
RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS
Acta Neuropathologica, vol. 147, 50Contributions to Journals: ArticlesSOP and tick-sheet for using TDP-43 RNA aptamer (TDP-43APT) to detect pathological TDP-43 in FFPE-preserved human tissue, as described in Spence and Waldron et al., 2024 (Acta Neuropathologica) v1
protocols.io.Other Contributions: Other Contributions- [ONLINE] DOI: https://doi.org/10.17504/protocols.io.eq2lyjo4mlx9/v1
- Research
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Funding and Grants
A Laboratory Model for Antiviral Immunity in Molluscs (co-writer); £201,732 | 2018-06 to 2021-10 | Grant | The Leverhulme Trust (London, GB)
Establishment of a Laboratory Model for Antiviral Immunity in Molluscs (co-writer); £44,364 | 2017-04 to 2017-12 | Grant | Wellcome Trust ISSF (London, GB)
Antiviral immune expression in the mollusc Lymnaea stagnalis (co-writer); £1,791 | 2017-02 to 2017-06 | Grant | University of Edinburgh Moray Endowement Fund (Edinburgh, GB)
Next Generation Sequencing workshop hosted by the Vienna Graduate School of Population Genetics Registration and Travel Award; €1,000 | 2011-05 to 2011-06 | AwardEuropean Science Foundation (Strasbourg, FR)
St. John’s College, Cambridge Learning and Research Fund; £1,000 | 2010-06 to 2010-07 | Award | St. John's College, University of Cambridge (Cambridge, GB)
Summer Institute in Statistics and Modelling in Infectious Diseases workshop hosted by The University of Washington Registration and Travel Award; $4,000 | 2010-06 to 2010-07 | Award | National Institutes of Health (Bethesda, Maryland, US)
Marie Curie Early Stage Research Fellowship; £24,055 | 2007-09 to 2008-08 | Salary award | Marie Curie (London, GB)
Embark Initiative Thermadapt Programme Research Fellowship; €38,012 | 2003-09 to 2005-08 | Salary award | Irish Research Council (Dublin, IE)
- Publications
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Correction: Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes
PLoS Genetics, vol. 16, no. 3, e1008679Contributions to Journals: ArticlesTargeting mitochondrial dysfunction in amyotrophic lateral sclerosis: a systematic review and meta-analysis
Brain Communications, vol. 1, no. 1, fcz009Contributions to Journals: ArticlesCreation and maintenance of Ashworth outcrossed DGRP population V.1
protocols.io.Other Contributions: Other Contributions- [ONLINE] DOI: https://doi.org/10.17504/protocols.io.zbuf2nw
Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes.
PLoS Genetics, vol. 14, no. 7, e1008679Contributions to Journals: ArticlesThe virome of Drosophila suzukii, an invasive pest of soft fruit
Virus Evolution, vol. 4, no. 1, vey009Contributions to Journals: ArticlesThe virome of Drosophila suzukii, an invasive pest of soft fruit
Working Papers: Preprint Papers- [ONLINE] DOI: https://doi.org/10.1101/190322
Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes
Working Papers: Preprint Papers- [ONLINE] DOI: https://doi.org/10.1101/166488
- [ONLINE] http://dx.doi.org/10.1101/166488
Protocol for a systematic review and meta-analysis of experimental models of amyotrophic lateral sclerosis
Evidence-based Preclinical Medicine, vol. 3, no. 2, pp. 17-19Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/ebm2.23
- [ONLINE] https://onlinelibrary.wiley.com/doi/10.1002/ebm2.23
The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster
PLoS Biology, vol. 13, no. 7, e1002210Contributions to Journals: ArticlesElevated levels of expression associated with regions of the Drosophila genome that lack crossing over
Biology Letters, vol. 4, no. 6, pp. 758-761Contributions to Journals: Articles
