![Professor David J. Blackbourn Professor David J. Blackbourn](/img/200x200/staffpages/uploads/s03db1/avatar/lipxatHB9UB7Xwd8IeX4GisU5S4ec8bQyulDDZhj.jpeg)
Professor of Virology, Interim Head of School
- About
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- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
David’s PhD (1990) is in molecular genetics and he has worked on different aspects of virology and immunology including in the USA, where he worked at the University of California (UC) for nine years on HIV and Kaposi’s sarcoma herpesvirus (KSHV), including six years with Dr Jay A. Levy.
David’s research more recently has focused on viruses that are responsible for causing cancer. In particular, he concentrates on how such viruses hide from the immune system. By studying human viruses that have evolved with their host for at least 25 million years, David believes that unique insight into the workings of the immune system can be gained. This knowledge can then be put to good use to treat immune system disorders. Techniques include a combination of molecular virology and immunology.
He has either authored or co-authored over £8m in funded research grant awards and published over 75 manuscripts that have been cited over 5000 times (Google Scholar), with two papers cited over 600 times each and a further three papers cited over 200 times each.
David returned to the UK from the USA in 1999 to his first lectureship at the University of Glasgow. In 2005 he moved to the University of Birmingham and received his Chair there in 2010. He moved to the University of Surrey to be Head of the Department of Microbial Sciences in August 2013 and in December of that year was appointed Head of the School of Biosciences and Medicine, consisting of four departments, a clinical trials faciility and a clinical trials unit. He held that position for eight years.
David is proud to have been appointed Director of the Institute of Medical Sciences at the University of Aberdeen, commencing January 2022.
ORCID ID: https://orcid.org/0000-0002-6703-4497
External Memberships
David is one of three Founding Directors of Ducentis Biotherapeutics (www.ducentisbio.com) established in 2015 to exploit his research findings to create next generation anti-inflammatory and autoimmune medicines. David serves as a non-executive board member for Ducentis, which has secured c£4m in start-up funding, including from LifeArc.
He is one of three Editors-in-Chief for FEMS Microbiology Reviews (https://academic.oup.com/femsre), which publishes invited comprehensive and authoritative reviews on all aspects of microbiology from leading authors. FEMS Microbiology Reviews ranked 6th of 134 Microbiology journals in the 2020 Journal Citation Reports.
Latest Publications
Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)
Critical Reviews in Clinical Laboratory Sciences, vol. 60, no. 3, pp. 189-211Contributions to Journals: Review articlesVitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort
Nutrients, vol. 13, no. 11, 4104Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3390/nu13114104
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/17816/1/Vearing_etal_Vitamin_D_Status_VOR.pdf
- [ONLINE] View publication in Scopus
KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection
Cell Reports, vol. 35, no. 5, 109056Contributions to Journals: ArticlesVery high prevalence of 25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: Analysis of the UK Biobank Cohort
British Journal of Nutrition, vol. 125, no. 4, pp. 448-459Contributions to Journals: ArticlesMembrane-associated and secreted forms of the rhesus macaque rhadinovirus-encoded CD200 homologue and cellular CD200 demonstrate differential effects on rhesus macaque CD200 receptor signaling and regulation of myeloid cell activation
Journal of Virology, vol. 95, no. 5, e01654-20Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/JVI.01654-20
- [ONLINE] View publication in Scopus
- Research
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Research Areas
Accepting PhDs
I am currently accepting PhDs in Biomedical Sciences.
Please get in touch if you would like to discuss your research ideas further.
Biomedical Sciences
Accepting PhDs - Publications
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Page 2 of 2 Results 51 to 79 of 79
The restricted cellular host range of human herpesvirus 8
AIDS, vol. 14, no. 9, pp. 1123-1133Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/00002030-200006160-00009
- [ONLINE] View publication in Scopus
Suppression of human immunodeficiency virus type 1 replication by a soluble factor produced by CD8 + lymphocytes from HIV-2-infected baboons
Immunology Letters, vol. 66, no. 1-3, pp. 151-157Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0165-2478(98)00175-8
- [ONLINE] View publication in Scopus
Increased human herpesvirus 8 seroprevalence in young homosexual men who have multiple sex contacts with different partners
Journal of Infectious Diseases, vol. 179, no. 1, pp. 237-239Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1086/314570
- [ONLINE] View publication in Scopus
Human immunodeficiency virus-2 infection in baboons is an animal model for human immunodeficiency virus pathogenesis in humans
Archives of Pathology and Laboratory Medicine, vol. 122, no. 6, pp. 523-533Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells
Journal of Virology, vol. 72, no. 6, pp. 5182-5188Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/jvi.72.6.5182-5188.1998
- [ONLINE] View publication in Scopus
Transient virus infection and pathogenesis of a new HIV type 2 isolate, UC12, in baboons
AIDS Research and Human Retroviruses, vol. 14, no. 1, pp. 79-82Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1089/aid.1998.14.79
- [ONLINE] View publication in Scopus
CD8 cell noncytotoxic antiviral activity in human immunodeficiency virus-infected and -uninfected children
Journal of Infectious Diseases, vol. 177, no. 2, pp. 470-472Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1086/517378
- [ONLINE] View publication in Scopus
Human herpesvirus 8 detection in nasal secretions and saliva
Journal of Infectious Diseases, vol. 177, no. 1, pp. 213-216Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1086/517356
- [ONLINE] View publication in Scopus
Infectious human herpesvirus 8 in a healthy North American blood donor
Lancet, vol. 349, no. 9052, pp. 609-611Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(96)10004-0
- [ONLINE] View publication in Scopus
CD8+ cells from HIV-2-infected baboons control HIV replication
AIDS, vol. 11, no. 6, pp. 737-746Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1097/00002030-199706000-00006
- [ONLINE] View publication in Scopus
Human herpesvirus 8 in semen and prostate
AIDS, vol. 11, no. 2, pp. 249-250Contributions to Journals: Editorials- [ONLINE] DOI: https://doi.org/10.1097/00002030-199702000-00016
- [ONLINE] View publication in Scopus
Superinfection with human immunodeficiency virus type 2 can reactivate virus production in baboons but is contained by a CD8 T cell antiviral response
Journal of Infectious Diseases, vol. 176, no. 4, pp. 948-959Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1086/516544
- [ONLINE] View publication in Scopus
Suppression of HIV replication by lymphoid tissue CD8+ cells correlates with the clinical state of HIV-infected individuals
Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 23, pp. 13125-13130Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1073/pnas.93.23.13125
- [ONLINE] View publication in Scopus
Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients
Lancet, vol. 348, no. 9031, pp. 858-861Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0140-6736(96)03240-0
- [ONLINE] View publication in Scopus
Molecular cloning of the human immunodeficiency virus subtype 2 strain HIV-2(UC2)
Virology, vol. 222, no. 1, pp. 257-261Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/viro.1996.0417
- [ONLINE] View publication in Scopus
Susceptibility of peripheral blood mononuclear cells from gorillas, orangutans and baboons to diverse HIV isolates
AIDS, vol. 10, no. 12, pp. 1438-1440Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1097/00002030-199610000-00023
- [ONLINE] View publication in Scopus
CD8+ T cells suppress human immunodeficiency virus replication by inhibiting viral transcription
Proceedings of the National Academy of Sciences of the United States of America, vol. 92, no. 6, pp. 2308-2312Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1073/pnas.92.6.2308
- [ONLINE] View publication in Scopus
Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients
Science, vol. 268, no. 5210, pp. 582-583Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1126/science.7725108
- [ONLINE] View publication in Scopus
Suppression of HIV Replication by CD8+ Cell Clones Derived from HIV-Infected and Uninfected Individuals
Cellular Immunology, vol. 159, no. 2, pp. 271-279Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/cimm.1994.1313
- [ONLINE] View publication in Scopus
Inhibition of simian immunodeficiency virus (SIV) replication by CD8 + cells of SIV‐infected rhesus macaques: Implications for immunopathogenesis
Journal of Medical Primatology, vol. 23, no. 6, pp. 343-354Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1600-0684.1994.tb00297.x
- [ONLINE] View publication in Scopus
60th forum in immunology: General discussion
Research in Immunology, vol. 145, no. 8-9, pp. 714-724 (715)Contributions to Journals: ArticlesEmergence of antigenic variants of simian immunodeficiency virus (SIVmac) in a seronegative macaque SIVmac239 infection
Cellular and Molecular Biology Research, vol. 40, no. 7-8, pp. 661-669Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Human CD8+ cell non-cytolytic anti-HIV activity mediated by a novel cytokine
Research in Immunology, vol. 145, no. 8-9, pp. 653-659Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0923-2494(05)80049-5
- [ONLINE] View publication in Scopus
Th1/Th2 cytokines in AIDS: sorting out the confusion
Research in Immunology, vol. 145, no. 8-9, pp. 715Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1016/S0923-2494(05)80062-8
- [ONLINE] View publication in Scopus
A Simple Method to Distinguish Between Simian Immunodeficiency Virus Isolates by Restriction Analysis of PCR Products
DNA and Cell Biology, vol. 12, no. 7, pp. 617-622Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1089/dna.1993.12.617
- [ONLINE] View publication in Scopus
Simian opioid dependency, immune function and SAIDS
NIDA Research Monograph Series, no. 132, pp. 71Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Detection of simian immunodeficiency virus RNA from infected rhesus macaques by the polymerase chain reaction
Journal of Virological Methods, vol. 37, no. 2, pp. 109-117Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/0166-0934(92)90038-F
- [ONLINE] View publication in Scopus
Effects of in vivo and in vitro administration of morphine sulfate upon rhesus macaque polymorphonuclear cell phagocytosis and chemotaxis
Journal of Pharmacology and Experimental Therapeutics, vol. 263, no. 2, pp. 533-539Contributions to Journals: Articles- [ONLINE] View publication in Scopus
Evaluation of anti-SIV potential of anti-neoplastic anthracyclines
Proceedings of the Western Pharmacology Society, vol. 35, pp. 141-146Contributions to Journals: Articles- [ONLINE] View publication in Scopus