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Professor Claude Wischik

Professor Claude Wischik
Professor Claude Wischik
Professor Claude Wischik

Chair in Mental Health (Clin)

About
Email Address
c.m.wischik@abdn.ac.uk
Office Address

TauRx Therapeutics Ltd

1st Floor, Sir Moir Lockhead Building

395 King Street

Aberdeen

AB24 5RP

United Kingdom

School/Department
School of Medicine, Medical Sciences and Nutrition
Research

Research Overview

Molecular Neuropathology of Alzheimer's Disease, and in particular the therapeutic intervention of tau pathology

Publications

Page 4 of 4 Results 76 to 100 of 100

  • Ligands for aggregated tau molecules: WO2010034982

    Kemp, S. J., Storey, J. M. D., Rickard, J. E., Harrington, C. R., Horsley, D., Wischik, C. M., Clunas, S., Heinrich, T.
    Patents: Patents

  • Rationale for tau aggregation inhibitor therapy in Alzheimer's disease and other tauopathies

    Wischik, C. M., Wischik, D. J., Storey, J. M. D., Harrington, C. R.
    Emerging drugs and targets for Alzheimer's disease: Volume 1: Beta-Amyloid, Tau Protein and Glucose Metabolism. Martinez, A. (ed.), pp. 210-232, 23 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Lewy body variant of Alzheimer's disease: selective neocortical loss of t-SNARE proteins and loss of MAP2 and alpha-synuclein in medial temporal lobe

    Mukaetova-Ladinska, E. B., Xuereb, J. H., Garcia-Sierra, F., Hurt, J., Gertz, H. J., Hills, R., Brayne, C., Huppert, F. A., Paykel, E. S., McGee, M. A., Jakes, R., Honer, W. G., Harrington, C. R., Wischik, C. M., CC75C Collaboration Group
    The Scientific World Journal, vol. 9, pp. 1463-1475
    Contributions to Journals: Articles

  • Therapeutic Use of Diaminophenothiazines: WO2009044127

    Wischik, C. M., Damon J., W., Storey, J. M. D., Harrington, C. R.
    Patents: Patents

  • Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine

    Deiana, S., Harrington, C. R., Wischik, C. M., Riedel, G.
    Psychopharmacology, vol. 202, no. 1-3, pp. 53-65
    Contributions to Journals: Articles

  • Methods of synthesis and/or purification of diaminophenothiazinium compounds

    Wischik, C. M., Storey, J. M. D., Marshall, C., Sinclair, J. P., Baddeley, T.
    Patents: Patents

  • Thiazin red as a neuropathological tool for the rapid diagnosis of Alzheimer's disease in tissue imprints

    Luna-Munoz, J., Peralta-Ramirez, J., Chavez-Macias, L., Harrington, C. R., Wischik, C. M., Mena, R.
    Acta Neuropathologica, vol. 116, no. 5, pp. 507-515
    Contributions to Journals: Articles

  • Inhibitors of protein aggregation: WO2007110629

    Wischik, C. M., Rickard, J. E., Horsley, D., Harrington, C. R.
    Patents: Patents

  • A55 A rCBF study of hallucinations in dementia.

    Staff, R. T., Benjamin, K. D., Murray, A. D., Gemmell, H. G., Wischik, C. M.
    Nuclear Medicine Communications, vol. 27, no. 3, 295
    Contributions to Journals: Abstracts

  • Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC)

    Storey, J. M. D., Sinclair, J. P., Marshall, C., Tan, H. W., Wischik, C. M.
    Patents: Patents

  • Inhibition of tau-tau-association

    Wischik, C. M., Edwards, P. C., Harrington, C. R., Roth, M., Klug, A.
    Patents: Patents

  • Alzheimer's disease

    Wischik, C. M., Harrington, C. R., Roth, M.
    The Oxford Companion to The Mind. Gregory, R. (ed.). 2 edition. Oxford University Press, pp. 24-27, 4 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Naphthoquinone-type inhibitors of protein aggregation

    Wischik, C. M., Horsley, D., Rickard, J. E., Harrington, C. R.
    Patents: Patents

  • Materials and methods relating to protein aggregation in neurodegenerative disease: WO2002059150

    Wischik, C. M., Rickard, J. E., Horsley, D., Harrington, C. R.
    Patents: Patents

  • Loss of synaptic but not cytoskeletal proteins in the cerebellum of chronic schizophrenics

    Mukaetova-Ladinska, E. B., Hurt, J., Honer, W. G., Harrington, C. R., Wischik, C. M.
    Neuroscience Letters, vol. 317, no. 3, pp. 161-165
    Contributions to Journals: Articles

  • Inhibition of tau-tau-association

    Wischik, C. M., Edwards, P. C., Harrington, C. R., Roth, M., Klug, A.
    Patents: Patents

  • Materials and methods relating to protein aggregation in neurodegenerative disease: WO2002055720

    Wischik, C. M., Horsley, D., Rickard, J. E., Harrington, C. R.
    Patents: Patents

  • Neurofibrillary labels

    Wischik, C. M., Harrington, C. R., Rickard, J. E., Horsley, D.
    Patents: Patents

  • Accumulation of C-terminally truncated tau protein associated with vulnerability of the perforant pathway in early stages of neurofibrillary pathology in Alzheimer’s disease

    Garcia-Sierra, F., Wischik, C. M., Harrington, C. R., Luna-Munoz, J., Mena, R.
    Journal of Chemical Neuroanatomy, vol. 22, no. 1-2, pp. 65-77
    Contributions to Journals: Articles

  • Loss of synaptic, but not cytoskeletal proteins in the cerebellum of people with chronic schizophrenia

    Mukaetova-Ladinska, E. B., Hurt, J., Honer, W. G., Harrington, C. R., Wischik, C. M.
    Schizophrenia Research, vol. 49, no. Suppl. 1, pp. 55
    Contributions to Journals: Abstracts

  • The molecular basis of tau protein pathology in Alzheimer's Disease and related neurodegenerative dementias

    Wischik, C. M., Theuring, F., Harrington, C. R.
    Neurobiology of Alzheimer’s Disease. Dawbarn, D., Allen, S. (eds.). 2 edition. Oxford University Press
    Chapters in Books, Reports and Conference Proceedings: Chapters

  • Staging of cytoskeletal and beta-amyloid changes in human isocortex reveals biphasic synaptic protein response during progression of Alzheimer's disease

    Mukaetova-Ladinska, E. B., Garcia-Siera, F., Hurt, J., Gertz, H. J., Xuereb, J. H., Hills, R., Brayne, C., Huppert, F. A., Paykel, E. S., McGee, M., Jakes, R., Honer, W. G., Harrington, C. R., Wischik, C. M.
    American Journal of Pathology, vol. 157, no. 2, pp. 623-636
    Contributions to Journals: Articles

  • α-Synuclein inclusions in Alzheimer and Lewy body diseases

    Mukaetova-Ladinska, E. B., Hurt, J., Jakes, R., Xuereb, J., Honer, W. G., Wischik, C. M.
    Journal of Neuropathology and Experimental Neurology, vol. 59, no. 5, pp. 408-417
    Contributions to Journals: Articles

  • The extent of neurofibrillary pathology in perforant pathway neurons is the key determinant of dementia in the very old

    Garcia-Sierra, F., Hauw, J. J., Duyckaerts, C., Wischik, C. M., Luna-Munoz, J., Mena, R.
    Acta Neuropathologica, vol. 100, pp. 29-35
    Contributions to Journals: Articles

  • alpha-synuclein inclusions in Alzheimer and Lewy body diseases

    Mukaetova-Ladinska, E. B., Hurt, J., Jakes, R., Xuereb, J., Honer, W. G., Wischik, C. M.
    Journal of Neuropathology and Experimental Neurology, vol. 59, pp. 408-417
    Contributions to Journals: Articles
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