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Professor Amanda Lee

Professor Amanda Lee
Professor Amanda Lee
Professor Amanda Lee

Chair in Medical Statistics

About
Email Address
a.j.lee@abdn.ac.uk
Telephone Number
+44 (0)1224 437111
Office Address

Institute of Applied Health Sciences, Room 1.005 Polwarth Building, Foresterhill

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Following graduation with an MSc Medical Statistics from Newcastle University in 1987, I worked as a research statistician in the Cardiovascular Epidemiology Unit, University of Dundee between 1987-1993.  After successful award of my PhD, I moved to the Wolfson Unit for Peripheral Vascular Diseases, University of Edinburgh and worked as a senior research fellow for 9 years. 

In 2003, I joined the Univeristy of Aberdeen as medical statistician for the Department of Primary Care.  I was made Reader in 2004 and attained Professor in 2006. I held the post of Deputy Director of the Institute of Applied Health Sciences (IAHS) between 2011-2018 and was then appointed Director of the IAHS between 2018-2023.  In 2024, I took on role as IAHS EDI Lead.  

Memberships and Affiliations

Internal Memberships
  • EDI Lead for the Institute of Applied Health Sciences (2024-)
  • Director of the Institute of Applied Health Sciences (2018-2023)
  • Deputy Director of the Institute of Applied Health Sciences (2011-2018)
  • Non Ex Officio member of University Senate (2015-2023)
  • Member of Joint Consultative Committee Redundancy Avoidance (JCCRA) Policy Review Working Group (2018-)
  • Member of the University On-line Education Steering Group (2017-2022)
  • Member of University Workload Review Group (2019-2023)
  • Member of University Values & Culture Working Group (2018-2019)
  • Member of University Space Enhanced Teaching Working Group (2018-9)
  • Chair of the Institute of Applied Health Sciences Athena SWAN SAT (2015-2021)
  • Chair of the Institute of Applied Health Science Postgraduate Education Group (2014-2019)
  • Member of the Institute of Applied Health Sciences Staff Development Group (2011-)
  • Chair of the School of Medicine, Medical Sciences and Nutrition Staff Development Group (2016-2022)
  • Member of Sciences Promotions Sub-Committee (2019)
  • Member of the College of Life Sciences & Medicine Promotions sub-committee (2017)
  • Chair of Institute of Applied Health Sciences Staff Development Group (2011-2016)
  • Deputy Head of Section of Population Health, College of Life Sciences and Medicine (2009-2011)
External Memberships
  • Panel member of Ireland Health Research Board Secondary Data Analysis Review Board (2019-)
  • Panel member of NIHR Clinical doctoral fellowship Programme (2018-)
  • Panel member of NIHR Policy Research Programme (2017)
  • Statistician for the CSO Health Services and Population Health Research Committee (HSRPP) (2010-2018)
  • Statistician for the Asthma UK grant committee (2008-2010)
  • External examiner for MSc Applied Health Statistics, University of Dundee (2011-2012; programme then withdrawn)
  • Role model for the Aurora, the Leadership Foundation development initiative for women (2016-)
  • Statistical Editor for the International Journal of Pharmacy Practice (2012-)
  • Editorial board member for the Pragmatic and Observational Research on-line Journal (2009-)
  • Data monitoring committee statistician for ‘Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT-Lung test’ (2012-2019)
  • Member of the Programme Steering Committee of ISCOMAT: Improving the safety and continuity of medicines management at care transitions (2016-)
  • Chair of the steering group for ‘Safety Assessment of Marketed Medicines (SAMM) for Ciclesonide’ (2005-2008)
  • Data monitoring committee member for the ‘Randomised controlled trial comparing foam sclerotherapy, alone or in combination with endovenous laser therapy, with conventional surgery as a treatment for varicose veins’ (2002-2003)
  • Data monitoring and ethics committee member for the MRC-funded USABLE (ulcer surgery as adjuvant to bandaging with 4-layers - evaluation) Trial (2002-2004)
  • Steering committee member for the ECoSSE study (a multicentred RCT on the efficacy and cost-effectiveness of selective single embryo transfer) (2004-2006)
  • Steering committee member for a MRC programme grant on inflammation, glucocorticoids and microvascular disease in the aetiology of cognitive impairment in type 2 diabetes (2002-2006)

 

Latest Publications

View My Publications

Research

Research Overview

Applied Medical Statistics

Epidemiology of Vascular Diseases

Research Areas

Applied Health Sciences

View Research Area

Research Specialisms

  • Health Sciences
  • Medical Statistics
  • Epidemiology

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Supervision

Successful PhD students

Ms Alyson Kettles – ‘Nursing models, theories and care planning’  University of Aberdeen, successfully awarded March 2005.

Ms Ionna Tzoulaki – ‘Subclinical markers in the aetiology of cardiovascular disease’  University of Edinburgh, successfully awarded March 2007.

Ms Nicola Gray – ‘Assessing the psychosocial impact on women of a low-grade abnormal cervical smear result and its subsequent management’  University of Aberdeen, successfully awarded March 2008.

Dr Mike Thomas – ‘Relationship between dysfunctional breathing and asthma’ University of Aberdeen, successfully awarded July 2010.

Dr. Atika Al Khazraji – ‘A study of common skin disease occurring in children in the United Arab Emirates’  University of Aberdeen, successfully awarded July 2010.

Ms Paraskevi Tsiamalou Broti – ‘Students' and educators’ perceptions about the nursing assessment in Higher Education in Greece’  University of Aberdeen, successfully awarded Feb 2011.

Ms Naiyana Metha – ‘Social support and health related quality of life in patients with coronary artery disease’  University of Aberdeen, successfully awarded Dec 2012.

Ms Breda Anthony – ‘Ways to improve acceptability for anxious women who come to out patient colposcopy clinics for treatment of cervical intro-epithelial neoplasia.’ University of Aberdeen, successfully awarded June 2013.

Dr Angus MacLeod – ‘Identification of prognostic factors and development of prognostic models in Parkinsons disease using long-term data from a large, incidence based cohort.  University of Aberdeen, successfully awarded June 2016.

Ms Christiane Pflanz-Sinclair – ‘Managing Change: What is the Best Model for Implementing Substance Misuse Screening Services in Primary Care in the United Arab Emirates/Middle East?’ University of Aberdeen, successfully awarded June 2019.

Dr Duncan Scrimgeour – ‘Does the MRCS predict surgical training outcomes and the FRCS?’  University of Aberdeen, successfully awarded June 2019.

Dr Ricky Ellis – ‘Predicting success at the Intercollegiate Membership of the Royal Colleges of Surgery (MRCS) examination’  University of Aberdeen, successfully awarded June 2022.

Successful MRes student

Ms Tobi Afariogun (MSc Health Services & Public Health Research) – ‘The provision of public health services in a community pharmacy setting: Exploring pharmacy undergraduate students’ opinions in the UK and Thailand’  University of Aberdeen, sucessfully awarded September 2008.

Funding and Grants

In 2024, I currently hold, or have held, 84 research grants with a total combined income of over £12 million.

Teaching

Teaching Responsibilities

  • Member of the IAHS Postgraduate Education Group (2013-)
  • Originator and Programme Co-ordinator of PgCert Research Methods for Health (63B990VZ) on-line course (2014-)
  • Lecturer and marker on the Applied Statistics (PU5522) postgraduate on-line course (2014-)
  • Lecturer on the Fundamentals of Research Design (PU5027) postgraduate on-line course (2014-)
  • Lecturer on the Epidemiology (PU5538) postgraduate on-line course (2014-)
  • Originator and lecturer on several staff CPD courses including ‘SPSS for Beginners’, ‘Intermediate SPSS’, ‘Introductory Medical Statistics’ and ‘Intermediate Medical Statistics’ (2011-)
  • Originator and lecturer on 3 day generic postgraduate basic statistics course for the University Graduate School (2008-)
  • Lecturer for GP Registrars (NHS Education) (2010-)
  • Lecturer on the MBChB Phase II 3M course (2013-2015)
  • Lecturer on the BSc Health Sciences 2nd year HE2501 ‘Elementary Statistics for Health Research’ course (2008-2010)
  • Lecturer on the MSc/Pg Dip/Pg Cert in Nursing/Midwifery/Health Care ‘Research Methods’ course (2006-2012)
  • Lecturer on the MSc/Pg Dip/Pg Cert in Nursing/Midwifery/Health ‘Using Evidence in Practice’ course (2006-2012)
  • Lecturer on the Foundation Year academic medics course (2008-2010)
  • Co organiser and co-lecturer for an ‘Introductory Statistics’ course forming part of the University of Edinburgh Transferable Skills Programme for postgraduate students (1998-2005).
  • Co-organiser and co-lecturer for an ‘Introductory Medical Statistics’ course aimed at academic researchers working in the University of Edinburgh and the Lothian University Hospitals NHS Trust (1998-2006).

Non-course Teaching Responsibilities

Personal tutor (2018-)

 

Publications

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  • Cancer risk among users of oral contraceptives: Cohort data from the Royal College of General Practitioners' Oral Contraception Study

    Hannaford, P. C., Selvaraj, S., Elliott, A. M., Angus, V. C., Iversen, L., Lee, A. J.
    British Medical Journal, vol. 335, no. 7621
    Contributions to Journals: Articles

  • Efficacy and safety of tiotropium in COPD patients in primary care: the SPiRiva Usual CarE (SPRUCE) study

    Freeman, D., Lee, A., Price, D. B.
    Respiratory Research, vol. 8, no. 45, 45
    Contributions to Journals: Articles

  • Costs of a Community Pharmacist-Led Medicines Management Service for Patients with Coronary Heart Disease in England: Healthcare System and Patient Perspectives

    Scott, A., Tinelli, M., Bond, C. M., Lee, A. J., The Community Pharmacy Medicines Management Project Evaluation Team
    Pharmacoeconomics, vol. 25, no. 5, pp. 397-411
    Contributions to Journals: Articles

  • Practice development plans to improve the primary care management of acute asthma: randomised controlled trial

    Foster, J. M., Hoskins, G., Smith, B., Lee, A. J., Price, D. B., Pinnock, H. J.
    BMC Family Practice, vol. 8, 23
    Contributions to Journals: Articles

  • Targeted screening for peripheral arterial disease in general practice: A pilot study in a high risk group

    Campbell, N. C., McNiff, C. A., Sheran, I. J., Brittenden, J., Lee, A. J., Ritchie, L. D.
    The British Journal of General Practice, vol. 57, no. 537, pp. 311-315
    Contributions to Journals: Articles

  • Trends in semen parameters in the northeast of Scotland

    Sripada, S., Fonseca, S., Lee, A., Harrild, K., Giannaris, D., Mathers, E. M., Bhattacharya, S.
    Journal of Andrology, vol. 28, no. 2, pp. 313-319
    Contributions to Journals: Articles

  • Short-course montelukast for intermittent asthma in children: a randomised controlled trial

    Robertson, C. F., Price, D., Henry, R., Mellis, C., Glasgow, N., Fitzgerald, D., Lee, A. J., Turner, L., Sant, M.
    American Journal of Respiratory and Critical Care Medicine, vol. 175, no. 4, pp. 323-329
    Contributions to Journals: Articles

  • A hydroxyapatite graft substitute reduces subsidence in a femoral impaction grafting model

    Munro, N. A., Downing, M. R., Meakin, J. R., Lee, A. J., Ashcroft, G. P.
    Clinical Orthopaedics and Related Research, vol. 455, pp. 246-252
    Contributions to Journals: Articles

  • Inflammatory, haemostatic, and rheological markers for incident peripheral arterial disease: Edinburgh Artery Study

    Tzoulaki, I., Murray, G. D., Lee, A. J., Rumley, A., Lowe, G. D. O., Fowkes, F. G. R.
    European Heart Journal, vol. 28, no. 3, pp. 354-362
    Contributions to Journals: Articles

  • A future career in general practice? A longitudinal study of medical students and pre-registration house officers

    Sinclair, H. K., Ritchie, L. D., Lee, A. J.
    European Journal of General Practice, vol. 12, pp. 120-127
    Contributions to Journals: Articles

  • Construct validity of the inhaled corticosteroid side effect questionnaire (ICQ)

    Foster, J., Van Sonderen, F. L. P., Lee, A. J., Sanderman, R., Van Der Molen, T.
    Proceedings of the American Thoracic Society, vol. 3
    Contributions to Journals: Articles

  • Reproducibility and patient acceptability of the inhaled corticosteroid questionnaire (ICQ): a patient self-reported side effect scale

    Foster, J., Van Sonderen, E., Lee, A. J., Sanderman, R., Dijkstra, A., Postma, D. S., Van Der Molen, T.
    European Respiratory Journal, vol. 28 (SUPPL 50)
    Contributions to Journals: Articles

  • Responsiveness of the inhaled corticosteroid questionnaire (ICQ): a patient self-reported side effect scale

    Foster, J., Van Sonderen, E., Lee, A. J., Sanderman, R., Dijkstra, A., Postma, D. S., Van Der Molen, T.
    European Respiratory Journal, vol. 28 (SUPPL 50)
    Contributions to Journals: Articles

  • A pragmatic, three-arm randomised controlled trial of spiritual healing for asthma in primary care

    Cleland, J. A., Price, D. B., Lee, A. J., Gerard, S., Sharma, A.
    The British Journal of General Practice, vol. 56, no. 527, pp. 444-449
    Contributions to Journals: Articles

  • Can pain be more or less neuropathic?: Comparison of symptom assessment tools with ratings of certainty by clinicians

    Bennett, M. I., Smith, B. H., Torrance, N., Lee, A. J.
    Pain, vol. 122, no. 3, pp. 289-294
    Contributions to Journals: Articles

  • The epidemiology of chronic pain of predominantly neuropathic origin: results from a general population survey

    Torrance, N., Smith, B. H., Bennett, M. I., Lee, A. J.
    Journal of Pain, vol. 7, no. 4, pp. 281-289
    Contributions to Journals: Articles

  • Hemostatic factors, inflammatory markers, and progressive peripheral atherosclerosis

    Tzoulaki, I., Murray, G. D., Price, J. F., Smith, F. B., Lee, A. J., Rumley, A., Lowe, G. D. O., Fowkes, F. G. R.
    American Journal of Epidemiology, vol. 163, no. 4, pp. 334-341
    Contributions to Journals: Articles

  • Reduced lung function in patients with abdominal aortic aneurysm is associated with activation of inflammation and hemostasis, not smoking or cardiovascular disease

    Fowkes, F. G. R., Anandan, C. L. C., Lee, A. J., Smith, F. B., Tzoulaki, I., Rumley, A., Powell, J. T., Lowe, G. D. O.
    Journal of Vascular Surgery, vol. 43, pp. 474-480
    Contributions to Journals: Articles

  • Scottish community pharmacists' current involvement in and attitudes towards ‘extended service’ provision: A national survey

    Inch, J. M., Bond, C. M., Lee, A. J., Scott, A., Grant, A. M.
    International Journal of Pharmacy Practice, vol. 13, no. 4, pp. 289-301
    Contributions to Journals: Articles

  • Long term effects of hysterectomy on mortality: nested cohort study

    Iversen, L., Hannaford, P. C., Elliott, A. M., Lee, A. J.
    British Medical Journal, vol. 330, pp. 1482-1485
    Contributions to Journals: Articles

  • Modelling the long term cost effectiveness of clopidogrel for the secondary prevention of occlusive vascular events in the UK

    Karnon, J., Brennan, A., Pandor, A., Fowkes, G., Lee, A. J., Gray, D., Coshall, C., Nicholls, C., Akehurst, R.
    Current Medical Research and Opinion, vol. 21, no. 1, pp. 101-112
    Contributions to Journals: Articles

  • Changing incidence of respiratory presentations in primary care; fact or artifact

    Simpson, C. R., Lee, A. J., Taylor, M. W., Helms, P. J. B.
    Archives of Disease in Childhood, vol. 90, pp. 982-983
    Contributions to Journals: Letters

  • Criteria for previously undiagnosed diabetes and risk of mortality: 15 year follow-up of the Edinburgh Artery Study cohort

    Wild, S. H., Smith, F. B., Lee, A. J., Fowkes, F. G. R.
    Diabetic Medicine, vol. 22, pp. 490-496
    Contributions to Journals: Articles

  • Are childhood asthma presentations in decline? Evidence from primary care

    Simpson, C. R., Taylor, M., Lee, A. J., Helms, P. J. B.
    Winter Meeting of the British Thoracic Society (2004), pp. 20-20
    Contributions to Journals: Abstracts

  • The health-related quality of life of people with peripheral arterial disease in the community: The Edinburgh Artery Study

    Dumville, J. C., Lee, A. J., Smith, F. B., Fowkes, F. G. R.
    British Journal of General Practice, vol. 54, no. 508, pp. 826-831
    Contributions to Journals: Articles

  • Improved prediction of fatal myocardial infarction using the ankle brachial index in addition to conventional risk factors: Edinburgh Artery Study

    Lee, A. J., Price, J. F., Russell, M. J., Smith, F. B., vanWijk, M. C. W., Fowkes, F. G.
    Circulation, vol. 110, pp. 3075-3080
    Contributions to Journals: Articles

  • Collaborative meta-analysis of prospective studies of plasma fibrinogen and cardiovascular disease

    Lee, A. J., The Fibrinogen Studies Collaboration
    European Journal of Cardiovascular Prevention and Rehabilitation, vol. 11, no. 1, pp. 9-17
    Contributions to Journals: Articles

  • Lifestyle and the risk of varicose veins

    Lee, A. J., Evans, C. J., Allan, P. L., Ruckley, C. V., Fowkes, F. G.
    Phlebology Digest, vol. 17, pp. 15-18
    Contributions to Journals: Articles

  • The health-related quality of life of people with peripheral arterial disease in the general population: Edinburgh Artery Study

    Dumville, J. C., Lee, A. J., Smith, F. B., Fowkes, F. G. R.
    The British Journal of General Practice, vol. 54, pp. 826-831
    Contributions to Journals: Articles

  • Lifestyle factors and the risk of varicose veins: Edinburgh Vein Study

    Lee, A. J., Evans, C. J., Allan, P. L., Ruckley, C. V., Fowkes, F. G.
    Journal of Clinical Epidemiology, vol. 56, no. 2, pp. 171-179
    Contributions to Journals: Articles

  • A 5cm colonic J pouch colo-anal reconstruction following anterior resection for low rectal cancer results in acceptable evacuation and continence in the long term

    Amin, A. I., Hallböök, O., Lee, A. J., Sexton, R., Moran, B. J., Heald, R. J.
    Colorectal Disease, vol. 5, no. 1, pp. 33-7
    Contributions to Journals: Articles

  • Changes in ankle brachial index in symptomatic and asymptomatic subjects in the general population

    Smith, F. B., Lee, A. J., Price, J. F., van Wijk, M. C. W., Fowkes, F. G.
    Journal of Vascular Surgery, vol. 38, pp. 1323-1330
    Contributions to Journals: Articles

  • Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease in the Edinburgh Artery Study

    Smith, F. B., Connor, J. M., Lee, A. J., Cooke, A., Lowe, G. D. O., Rumley, A., Fowkes, F. G. R.
    Thrombosis Research, vol. 112, pp. 209-216
    Contributions to Journals: Articles

  • The relationship between aortic wall distensibility and rupture of infrarenal abdominal aortic aneurysm

    Wilson, K. A., Lee, A. J., Hoskins, P. R., Fowkes, F. G., Ruckley, C. V., Bradbury, A. W.
    Journal of Vascular Surgery, vol. 37, pp. 112-117
    Contributions to Journals: Articles

  • Chronic venous insufficiency: clinical and duplex correlations. The Edinburgh Vein Study of venous disorders in the general population

    Ruckley, C. V., Evans, C. J., Allan, P. L., Lee, A. J., Fowkes, F. G. R.
    Journal of Vascular Surgery, vol. 36, no. 3, pp. 520-5
    Contributions to Journals: Articles

  • The effect of long saphenous vein stripping on quality of life

    MacKenzie, R. K., Paisley, A., Allan, P. L., Lee, A. J., Ruckley, C. V., Bradbury, A. W.
    Journal of Vascular Surgery, vol. 35, no. 6, pp. 1197-1203
    Contributions to Journals: Articles

  • Patient, operative, and surgeon factors that influence the effect of superficial venous surgery on disease-specific quality of life

    MacKenzie, R. K., Lee, A. J., Paisley, A., Burns, P., Allan, P. L., Ruckley, C. V., Bradbury, A. W.
    Journal of Vascular Surgery, vol. 36, no. 5, pp. 896-902
    Contributions to Journals: Articles

  • Lifestyle risk factors for lower limb venous reflux in the general population: Edinburgh Vein Study

    Fowkes, F. G., Lee, A. J., Evans, C. J., Allan, P. L., Bradbury, A. W., Ruckley, C. V.
    International Journal of Epidemiology, vol. 30, no. 4, pp. 846-852
    Contributions to Journals: Articles

  • Comparison of brachial artery pressure and derived central pressure in the measurement of abdominal aortic aneurysm distensibility

    Wilson, K. A., MacCallum, H., Wilkinson, I. B., Hoskins, P. R., Lee, A. J., Bradbury, A. W.
    European Journal of Vascular and Endovascular Surgery, vol. 22, pp. 355-360
    Contributions to Journals: Articles

  • Fibre intake, constipation and risk of varicose veins in the general population

    Lee, A. J., Evans, C. J., Hau, C. M., Fowkes, F. G.
    Journal of Clinical Epidemiology, vol. 54, pp. 423-429
    Contributions to Journals: Articles

  • Lipoprotein(a) and development of intermittent claudication and major cardiovascular events in men and women: The Edinburgh Artery Study

    Price, J. F., Lee, A. J., Rumley, A., Lowe, G. D. O., Fowkes, F. G.
    Arteriosclerosis Thrombosis and Vascular Biology, vol. 157, pp. 241-249
    Contributions to Journals: Articles

  • Most incompetent calf perforating veins are found in association with superficial venous reflux

    Stuart, W. P., Lee, A. J., Allan, P. L., Ruckley, C. V., Bradbury, A. W.
    Journal of Vascular Surgery, vol. 34, pp. 774-778
    Contributions to Journals: Articles

  • Prevalence and risk factors of chronic venous insufficiency

    Fowkes, F. G., Evans, C. J., Lee, A. J.
    Angiology, vol. 52, no. Suppl 1, pp. S5-S15
    Contributions to Journals: Articles

  • Investigation of factors which might indicate susceptibility to particulate air pollution

    Prescott, G. J., Lee, R., Cohen, G., Elton, R., Lee, A. J., Fowkes, F., Agius, R.
    Occupational and Environmental Medicine, vol. 57, no. 1, pp. 53-57
    Contributions to Journals: Articles

  • Randomized controlled trial of gamma-linolenic acid and eicosapentaenoic acid in peripheral arterial disease

    Leng, G. C., Lee, A. J., Fowkes, F. G., Jepson, R. G., Lowe, G. D., Skinner, E. R., Mowat, B. F.
    Clinical Nutrition, vol. 17, no. 6, pp. 265-271
    Contributions to Journals: Articles

  • Randomized controlled trial of antioxidants in intermittent claudication

    Leng, G. C., Lee, A. J., Fowkes, F. G. R., Horrobin, D., Jepson, R. G., Lowe, G. D., Rumley, A., Skinner, E. R., Mowat, B. F.
    Vascular Medicine, vol. 2, no. 4, pp. 279-285
    Contributions to Journals: Articles
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