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The School of Natural and Computing Sciences

Professor M Carmen Romano

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Professor M Carmen Romano
Professor M Carmen Romano
Professor M Carmen Romano

Personal Chair

About
Email Address
m.romano@abdn.ac.uk
Telephone Number
+44 (0)1224 272507
Office Address
Office 337, Institute for Complex Systems and Mathematical Biology, Department of Physics, Meston Building, Old Aberdeen Office 3:47, Institute of Medical Sciences, Foresterhill
School/Department
School of Natural and Computing Sciences
Research

Research Overview

I am interested in the understanding of fundamental biological processes using theoretical approaches based on nonlinear dynamics and statistical physics and combining them with experimental data. In particular, I am interested in the process of translation or synthesis of proteins, the coupling between transcription and translation, how ribosomes, the molecular machines that manufacture proteins, are synthesised, and its relationship to the cell cycle. I am furthermore interested in the effect of combinatorial stresses in yeast, as well as the effects of different types of stress on the cell cycle.

Funding and Grants

SULSA studentship (modeling of translation)/ SABR grant (Combinatorial Responses In Stress Pathways)/BBSRC grant (Ribosome Traffic Flow on the mRNA as a Regulator of Cellular Protein Production)
Teaching

Teaching Responsibilities

Electromagnetism (PX3008, 3rd year Physics) and Introduction to Mathematics and Modelling of Biological Systems (SB5005, MSc in Cell and Molecular Systems Biology)

Publications

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  • Dominant-negative release factors and their effect on termination and translational recoding events

    McFarland, M. R., Romano, M. C., Stansfield, I.
    Translation UK 2013
    Contributions to Conferences: Posters

  • Ribosome traffic on mRNAs maps to gene ontology: genome-wide quantification of translation initiation rates and polysome size regulation

    Ciandrini, L., Stansfield, I., Romano, M. C.
    PLoS Computational Biology , vol. 9, no. 1, e1002866
    Contributions to Journals: Articles

  • A yeast tRNA mutant that causes pseudohyphal growth exhibits reduced rates of CAG codon translation

    Kemp, A., Betney, R., Ciandrini, L., Schwenger, A. C., Romano, M. C., Stansfield, I.
    Molecular Microbiology, vol. 87, no. 2, pp. 284–300
    Contributions to Journals: Articles

  • Transport on a lattice with dynamical defects

    Turci, F., Parmeggiani, A., Pitard, E., Romano, M. C., Ciandrini, L.
    Physical Review. E, Statistical, Nonlinear and Soft Matter Physics, vol. 87, no. 1, 012705
    Contributions to Journals: Articles

  • Combinatorial stresses kill pathogenic Candida species

    Kaloriti, D., Tillmann, A., Cook, E., Jacobsen, M., You, T., Lenardon, M., Ames, L., Barahona, M., Chandrasekaran, K., Coghill, G., Goodman, D., Gow, N. A. R., Grebogi, C., Ho, H., Ingram, P., McDonagh, A., de Moura, A. P. S., Pang, W., Puttnam, M., Radmaneshfar, E., Romano, M. C., Silk, D., Stark, J., Stumpf, M., Thiel, M., Thorne, T., Usher, J., Yin, Z., Haynes, K., Brown, A. J. P.
    Medical Mycology, vol. 50, no. 7, pp. 699-709
    Contributions to Journals: Articles

  • A max-plus model of ribosome dynamics during mRNA translation

    Brackley, C. A., Broomhead, D. S., Romano, M. C., Thiel, M.
    Journal of Theoretical Biology, vol. 303, no. -, pp. 128-140
    Contributions to Journals: Articles

  • Impact of combinatorial stresses upon Candida albicans

    Kaloriti, D., Tillmann, A., Jacobsen, M., Yin, Z., Patterson, M., Radmaneshfar, E., You, T., Chandrasekaran, K., Pang, W., Coghill, G., de Moura, A. P. S., Thiel, M., Romano, M. C., Grebogi, C., Haynes, K., Quinn, J., Gow, N. A. R., Brown, A. J. P.
    Mycoses, vol. 55, no. Suppl. 4, pp. 15
    Contributions to Journals: Abstracts

  • A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi

    You, T., Ingram, P., Jacobsen, M. D., Cook, E., McDonagh, A., Thorne, T., Lenardon, M. D., de Moura, A. P. S., Romano, M. C., Thiel, M., Stumpf, M., Gow, N. A. R., Haynes, K., Grebogi, C., Stark, J., Brown, A. J. P.
    BMC Research Notes, vol. 5, 258
    Contributions to Journals: Articles

  • Multiple phase transitions in a system of exclusion processes with limited reservoirs of particles and fuel carriers

    Brackley, C., Ciandrini, L., Romano, M. C.
    Journal of statistical mechanics-Theory and experiment, vol. 2012, no. 3, P03002
    Contributions to Journals: Articles

  • Mixed population of competing totally asymmetric simple exclusion processes with a shared reservoir of particles

    Greulich, P., Ciandrini, L., Allen, R., Romano, M. C.
    Physical Review. E, Statistical, Nonlinear and Soft Matter Physics, vol. 85, no. 1, 011142
    Contributions to Journals: Articles
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