The insula represents a key neurobiological pain hub in psoriatic arthritis
Sunzini, F., Stefanov, K., Al-Wasity, S., Kaplan, C., Schrepf, A., Waller, N., Harte, S., Harris, R., Clauw, D. J., McLean, J., Siebert, S., Goodyear, C. S., Waiter, G. D., Basu, N.
Arthritis Research & Therapy, vol. 27, no. 1, pp. 70
Morbidity After Takotsubo Syndrome: A Report From the Scottish Takotsubo Registry
Rudd, A. E., Horgan, G. W., McGowan, J., Sood, A., McGeoch, R., Irving, J., Watt, J., Leslie, S. J., Petrie, M. C., Lang, C. C., Mills, N. L., Newby, D. E., Dawson, D.
Cereblon E3 Ligase Complex genes are expressed in tissues sensitive to thalidomide in chicken and zebrafish embryos but are unchanged following thalidomide exposure
Rosa Fraga, L., Reeves, J., Mahony, C., Erskine, L., Vargesson, N.
Linking epidemiology and genomics of maternal smoking during pregnancy in utero and in aging: a population-based study using human foetuses and the UK Biobank cohort
Mihov, M., Shoctor, H., Douglas, A., Hay, D. C., O'Shaughnessy, P. J., Iredale, J. P., Shaw, S., Fowler, P. A. F., Grassmann, F.
Actionable genetic variants in 4,198 Scottish participants from the Orkney and Shetland founder populations and implementation of return of results
Kerr, S. M., Klaric, L., Muckian, M. D., Johnston, K., Drake, C., Halachev, M., Cowan, E., Snadden, L., Dean, J., Zheng, S. L., Thami, P. K., Ware, J. S., Tzoneva, G., Shuldiner, A. R., Miedzybrodzka, Z., Wilson, J. F.
Cap-adjacent 2’-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1
Clemens, E., Brivo, S., Al-Khafaji, M. I., Eijlers, P., Kurukulasuriya, M. S., Haussmann, I. U., MacLeod, D., Wenzel, M., Muller, B., Soller, M., Pettitt, J.
Large scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy
Tadros, R., Zheng, S. L., Grace, C., Jordà, P., Francis, C., West, D. M., Jurgens, S. J., Thomson, K. L., Harper, A. R., Ormondroyd, E., Xu, X., Theotokis, P. I., Buchan, R. J., McGurk, K. A., Mazzarotto, F., Boschi, B., Pelo, E., Lee, M., Noseda, M., Varnava, A., Vermeer, A. M., Walsh, R., Amin, A. S., van Slegtenhorst, M. A., Roslin, N., Strug, L. J., Salvi, E., Lanzani, C., Marvao, A. d., Hypergenes InterOmics Collaborators, Roberts, J. D., Tremblay-Gravel, M., Giraldeau, G., Cadrin-Tourigny, J., L L'Allier, P., Garceau, P., Talajic, M., Gagliano Taliun, S. A., Pinto, Y. M., Rakowski, H., Pantazis, A., Bai, W., Baksi, J., Halliday, B. P., Prasad, S. K., Barton, P. J., O'Regan, D. P., Cook, S. A., de Boer, R. A., Christiaans, I., Michels, M., Kramer, C. M., Ho, C. Y., Neubauer, S., HCMR Investigators, Matthews, P. M., Wilde, A. A., Tardif, J., Olivotto, I., Adle, A., Goel, A., Ware, J. S., Bezzina, C. R., Watkins, H., Dawson, D.
Hydromethylthionine sustains truncated-tau-dependent inflammation-lowering effects in mouse brain
Coelho Dos Santos, R., Lee, S. H., Lofthouse, R. A., Melis, V., Strachan, L., Leith, M., Dreesen, E., Armstrong, P., Vorley, T., Goatman, E., Hull, C., Riedel, G., Wischik, C., Harrington, C.
The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fracture
Faber, B. G., Frysz, M., Zheng, J., Lin, H., Flynn, K. A., Ebsim, R., Saunders, F., Beynon, R., Gregory, J., Aspden, R. M., Harvey, N. C., Lindner, C., Cootes, T., Evans, D. M., Smith, G. D., Gao, X., Wang, S., Kemp, J. P., Tobias, J. H.
Human Molecular Genetics, vol. 34, no. 3, pp. 207-217
Myocardial ischaemia following COVID-19: a cardiovascular magnetic resonance study
Arnold, J. R., Yeo, J. L., Budgeon, C. A., Shergill, S., England, R., Shiwani, H., Artico, J., Moon, J. C., Gorecka, M., Roditi, G., Morrow, A., Mangion, K., Shanmuganathan, M., Miller, C. A., Chiribiri, A., Alzahir, M., Ramirez, S., Lin, A., Swoboda, P. P., McDiarmid, A. K., Sykes, R., Singh, T., Bucciarelli-Ducci, C., Dawson, D., Fontana, M., Manisty, C., Treibel, T. A., Levelt, E., Young, R., McConnachie, A., Neubauer, S., Piechnik, S. K., Davies, R. H., Ferreira, V. M., Dweck, M. R., Berry, C., McCann, G. P., Greenwood, J. P., Oxford Acute Myocardial Infarction OxAMI Study Investigators, COVID-HEART investigators
International Journal of Cardiovascular Imaging, vol. 41, no. 2, pp. 247-256
Differences in Brain Volume and Thickness between Shammah (Smokeless Tobacco) Users and Non-Users: A Cross-Sectional Study
Majrashi, N. A., Alyami, A. S., Almansour, M. A., Alyami, M. H., Almansour, M. H., Alhashlan, E., Shubayr, N., Hendi, A. M., Ageeli, W. A., Madkhali, Y., Alwadani, B., Refaee, T. A., Waiter, G. D.
British Journal of Hospital Medicine, vol. 86, no. 1, pp. 1-18
Butyrate-producing bacteria as probiotic supplement: beneficial effects on metabolism and modulation of behaviour in an obesity mouse model
Garcia-Serrano, A., Skoug, C., Axling, U., Korhonen, E., Teixeira, C., Ahrén, I., Mukhopadhya, I., Boteva, N., Martin, J., Scott, K., Gratz, S., Stenkula, K., Holm, C., Duarte, J.
Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the androgen receptor
Ahmed, I. M. M., Rofe, A., Henry, M. C., West, E., Jamieson, C., McEwan, I. J., Beveridge, R.
Monkeypox virus isolation from longitudinal samples in 11 hospitalised patients
Callaby, H., Olver, J., Emery, K., Richards, K. S., Killip, M., Groves, N., Beadsworth, M. B., Price, D. A., Cooke, G. S., Collini, P., Cole, J., Dunning, J., Semple, M. G., Baillie, J. K., Carson, G., Openshaw, P., Merson, L., Russell, C. D., Zambon, M., Chand, M., Tedder, R., Khoo, S., Horby, P., Turtle, L. C., Solomon, T., Ijaz, S., Fletcher, T., Palmarini, M., Ho, A., Price, N., Alex, B., Andrikopoulos, P., Black, B., Barclay, W. S., Bogaert, D., Chechi, K., Da Silva Filipe, A., De Silva, T., Docherty, A. B., Dos Santos Correia, G., Dumas, M. E., Green, C. A., Greenhalf, W., Griffin, J. L., Gupta, R., Harrison, E. M., Holden, K., Robertson, D., Scott, J. T., Stuart, D., ISARIC4C Investigators
The Lancet Infectious Diseases, vol. 25, no. 1, pp. e4-e5
Rivastigmine interferes with the pharmacological activity of hydromethylthionine on presynaptic proteins in the line 66 model of frontotemporal dementia
Schwab, K., Strachan, L., Anschuetz, A., Dreesen, E. S., Magbagbeolu, M., Melis, V., Theuring, F., Harrington, C., Wischik, C., Riedel, G.
A novel classifier of radiographic knee osteoarthritis for use on knee DXA images is predictive of joint replacement in UK Biobank
Beynon, R. A., Saunders, F. R., Ebsim, R., Faber, B. G., Jung, M., Gregory, J. S., Lindner, C., Aspden, R. M., Harvey, N. C., Cootes, T., Tobias, J. H.
Rheumatology Advances in Practice, vol. 9, no. 1, rkaf009
An optimised faecal microRNA sequencing pipeline reveals fibrosis in Trichuris muris infection
Layton, E., Goldsworthy, S., Yang, E., Ong, W. Y., Sutherland, T. E., Bancroft, A. J., Thompson, S., Au, V. B., Griffiths-Jones, S., Grencis, R. K., Fairhurst, A., Roberts, I. S.
Novel insights into carbohydrate utilisation, antimicrobial resistance, and sporulation potential in Roseburia intestinalis isolates across diverse geographical locations
Mukhopadhya, I., Martin, J., Shaw, S., Gutierrez Torrejon, M., Boteva, N., McKinley, A. J., Gratz, S., Scott, K.
Neural Correlates of Children with Avoidant Restrictive Food Intake Disorder (ARFID) Symptoms: Large-Scale Neuroanatomical Analysis of a Paediatric Population
Sader, M., Harris, H., Waiter, G., Jansen, P. W., Williams, J., White, T.
Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes
Mezincescu, A., Rudd, A. E., Cheyne, L., Horgan, G., Philip, S., Cameron, D., van Loon, L., Whitefield, P., Gribbin, R., Hu, M. K., Delibegovic, M., Fielding, B., Lobley, G., Thies, F., Newby, D. E., Gray, S., Henning, A., Dawson, D.
The profile of steroid hormones in human fetal and adult ovaries
Vazakidou, P., Evangelista, S., Li, T., Lecante, L. L., Rosenberg, K., Koekkoek, J., Salumets, A., Velthut-Meikas, A., Damdimopoulou, P., Mazaud-Guittot, S., Fowler, P. A., Leonards, P. E., van Duursen, M. B.
Reproductive Biology and Endocrinology, vol. 22, 60
Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial
Muir, K. W., Ford, G. A., Ford, I., Wardlaw, J. M., McConnachie, A., Greenlaw, N., Mair, G., Sprigg, N., Price, C. I., MacLeod, M. J., Dima, S., Venter, M., Zhang, L., O’Brien, E., Sanyal, R., Reid, J., Sztriha, L. K., Haider, S., Whiteley, W. N., Kennedy, J., Perry, R., Lakshmanan, S., Chakrabarti, A., Hassan, A., Marigold, R., Raghunathan, S., Sims, D., Bhandari, M., Wiggam, I., Rashed, K., Douglass, C., ATTEST-2 Investigators
The Lancet neurology, vol. 23, no. 11, pp. 1087-1096
Early Intervention in Patients with Asymptomatic Severe Aortic Stenosis and Myocardial Fibrosis
McCann, G. P., Ronak, R., Craig, N., Tsampasian, V., Molek-Dziadosz, P., Aslam, S., Lewis, S. C., Graham, C., White, A., MacGillivray, T., Tuck, C., Rayson, P., Cranley, D., Irvine, S., Armstrong, R., Milne, L., Hillis, G., Fairbairn, T., Greenwood, J. P., Steeds, R. P., Leslie, S., Bucciarelli-Ducci, C., Joshi, N., Kunadian, V., Vassiliou, V. S., Dungu, J., Prasad, S. K., Dawson, D., Treibel, T. A., Miller, C., Ripley, D., Prendergast, B., Singh, A., Mills, N. L., Chin, C., Dweck, M. R., Newby, D. E., Loganath, K.
JAMA
Contributions to Journals: Articles
Advances in Raman spectroscopy for characterising oral cancer and oral potentially malignant disorders
Hanna, K., Asiedu, A., Theurer, T., Muirhead, D., Speirs, V., Oweis, Y., Abu Eid, R.
Expert Reviews in Molecular Medicine, vol. 26, e25
High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease
Arastoo, M., Penny, L. K., Lofthouse, R. A., Abdallah, A., Abrahamsson, A., Marini, P., Melis, V., Riedel, G., Harrington, C., Wischik, C., Porter, A., Palliyil, S.
Evaluation of variation in preclinical electroencephalographic (EEG) spectral power across multiple laboratories and experiments: An EQIPD study
Ahuis, T. P., Smyk, M. K., Laloux, C., Aulehner, K., Bray, J., Waldron, A., Miljanovic, N., Seiffert, I., Song, D., Boulanger, B., Jucker, M., Potschka, H., Platt, B., Riedel, G., Voehringer, P., Nicholson, J. R., Drinkenburg, W. H. I. M., Kas, M. J. H., Leiser, S. C.
Author Correction: AI is a viable alternative to high throughput screening: a 318-target study (Scientific Reports, (2024), 14, 1, (7526), 10.1038/s41598-024-54655-z)
Giles, E., Heifets, A., Artía, Z., Inde, Z., Liu, Z., Zhang, Z., Wang, Z., Su, Z., Chung, Z., Frangos, Z. J., Li, Y., Yen, Y., Sidorova, Y. A., Tse-Dinh, Y. C., He, Y., Tang, Y., Li, Y., Pérez-Pertejo, Y., Gupta, Y. K., Zhu, Y., Sun, Y., Li, Y., Chen, Y., Aldhamen, Y. A., Hu, Y., Zhang, Y. J., Zhang, X., Yuan, X., Wang, X., Qin, X., Yu, X., Xu, X., Qi, X., Lu, X., Wu, X., Blanchet, X., Foong, W. E., Bradshaw, W. J., Gerwick, W. H., Kerr, W. G., Hahn, W. C., Donaldson, W. A., Van Voorhis, W. C., Zhang, W., Tang, W., Li, W., Houry, W. A., Lowther, W. T., Clayton, W. B., Greig, I. R., The Atomwise AIMS Program
Recognition and control of neutrophil extracellular trap formation by MICL
Malamud, M., Whitehead, L., McIntosh, A., Colella, F., Roelofs, A. J., Kusakabe, T., Dambuza, I. M., Phillips-Brookes, A., Salazar, F., Perez, F., Shoesmith, R., Zakrzewski, P., Sey, E. A., Rodrigues, C., Morvay, P. L., Redelinghuys, P., Bedekovic, T., Fernandes, M. J. G., Almizraq, R., Branch, D. R., Amulic, B., Harvey, J., Stewart, D., Yuecel, R., Reid, D. M., McConnachie, A., Pickering, M. C., Botto, M., Iliev, I. D., McInnes, I. B., De Bari, C., Willment, J. A., Brown, G. D.
Should Scotland Provide Genome-Wide Sequencing for the Diagnosis of Rare Developmental Disorders?: A Cost-Effectiveness Analysis
Abbott, M., Ryan, M., Hernández, R. A., McKenzie, L., Heidenreich, S., Hocking, L., Clark, C., Ansari, M., Moore, D., Lampe, A., McGowan, R., Berg, J., Miedzybrodzka, Z.
Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine
Cranston, A., Kraev, I., Stewart, M. G., Horsley, D., Robinson, L., Dreesen, E. S., Armstrong, P., Palliyil, S., Harrington, C., Wischik, C., Riedel, G.
Sex differences in coronary atherosclerotic plaque activity using 18F-sodium fluoride positron emission tomography
Kwiecińsk, J., Wang, K., Tzolos, E., Moss, A. J., Daghem, M., Adamson, P. D., Dey, D., Molek, P., Dawson, D., Arumugan, P., Sabharwal, N. K., Greenwood, J. P., Townend, J., Calvert, P. A., Rudd, J. H. F., Berman, D., Verjans, J. W., Williams, M. C.
European Journal of Nuclear Medicine and Molecular Imaging
Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection.
Ma, Q., Pradhan, A., Leaves, I., Hickey, E., Roselletti, E., Dambuza, I., Larcombe, D. E., de Assis, L. J., Wilson, D., Erwig, L. P., Netea, M. G., Childers, D. S., Brown, G. D., Gow, N. A. R., Brown, A. J. P.
A novel method to quantify fibrin–fibrin and fibrin–α2-antiplasmin cross-links in thrombi formed from human trauma patient plasma
Morrow, G. B., Flannery, S., Charles, P. D., Heilig, R., Feller, T., McQuilten, Z., Wake, E., Ariens, R. A. S., Winearls, J., Mutch, N. J., Fischer, R., Laffan, M. A., Curry, N.
Journal of Thrombosis and Haemostasis, vol. 22, no. 6, pp. 1758-1771
Dual-energy X-ray absorptiometry derived knee shape may provide a useful imaging biomarker for predicting total knee replacement: findings from a study of 37,843 people in UK Biobank.
Beynon, R., Saunders, F., Ebsim, R., Frysz, M., Faber, B., Gregory, J., Lindner, C., Sarmanova, A., Aspden, R. M., Harvey, N. C., Cootes, T., Tobias, J. H.
Osteoarthritis and Cartilage Open, vol. 6, no. 2, 100468
Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function
Quin, C., DeJong, E. N., Cook, E. K., Luo, Y. Z., Vlasschaert, C., Sadh, S., McNaughton, A. J., buttigieg, M. M., Breznik, J. A., Kennedy, A. E., Zhao, K., Mewburn, J., Dunham-Snary, K. J., Hindmarch, C. C., Bick, A. G., Archer, S. L., Rauh, M. J., Bowdish, D. M.
The Journal of Clinical Investigation, vol. 134, no. 11, e171002