PhD, DUniv (honoris causa), FInstP, FIPEM, FISMRM
Emeritus Professor
- About
-
- Email Address
- d.lurie@abdn.ac.uk
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Since my retirement in October 2021, I have been an Emeritus Professor at the University of Aberdeen. I previously held a Chair in Biomedical Physics at the University (2002-21), where I researched and taught MRI Physics, starting when I joined Jim Hutchison’s team in 1983.
My research was concerned with the development of MRI technology and its bio-medical applications, most recently in the area of Fast Field-Cycling MRI, which was pioneered by the group that I led. Whereas standard MRI scanners operate at a single magnetic field (e.g. 1.5 T or 3 T), FFC scanners have the ability to switch magnetic field rapidly during a scan, thereby obtaining information on the variation of the NMR relaxation times with magnetic field strength. Results indicate that this can provide a valuable new contrast mechanism for clinical MRI.
During my career I obtained research grants totalling over £11.1m as Principal Investigator. In 2015 a consortium of seven research laboratories and two companies, coordinated by me, secured €6.60m (£5.92m) from the European Union’s Horizon 2020 scheme to develop FFC-MRI as a clinical imaging modality; the “IDentIFY” project ran for 4 years from January 2016.
I have given over 100 invited, keynote and plenary lectures at conferences and workshops world-wide. I am author of 91 peer-reviewed papers, 8 book chapters as well as 291 conference abstracts.
My CV can be found here and my bibliography is available here.
Qualifications
- BSc (Hons) Natural Philosophy1979 - University of Aberdeen
- MSc Radiation Physics1980 - University of London
- PhD Medical Physics1984 - University of London
External Memberships
I was Chair of the Communications and Publications Committee of the European Federation of Organisations for Medical Physics (EFOMP) from January 2020 to February 2022.
Prizes and Awards
In 2017 I was awarded the Academic Gold Medal of the Institute of Physics and Engineering in Medicine (IPEM).
In 2021 I was awarded Senior Fellowship of the International Society for Magnetic Resonance in Medicine (ISMRM).
In 2022 I was given an Honorary Doctorate (D.Univ., honoris causa) by the University of the Highlands and Islands. - Publications
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Page 2 of 2 Results 101 to 173 of 173
Design and construction of a 0.2 T system for whole-body field-cycling MRI
Contributions to Conferences: PapersDetection of osteoarthritis in knee and hip joints by fast field-cycling NMR
Magnetic Resonance in Medicine, vol. 68, no. 2, pp. 358-362Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mrm.23266
Human relaxometry and MRI using fast field-cycling
AMPERE NMR School (2012), pp. 22Contributions to Conferences: AbstractsMeasurement of fibrin concentration by fast field-cycling NMR
Magnetic Resonance in Medicine, vol. 67, no. 5, pp. 1453–1457Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mrm.23117
QUANTITATIVE AND NON-INVASIVE DETECTION OF PROTEOGLYCAN BY FAST FIELD-CYCLING NUCLEAR MAGNETIC RESONANCE
World Congress on Osteoarthritis, pp. S92-S93Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1016/j.joca.2012.02.093
Absorption Methods for ESR and NMR Imaging of Solid Materials
MRI of Tissues with Short T2s or T2*s. Bydder, G., Young, I. (eds.). John Wiley & Sons Ltd., pp. 171-184, 14 pagesChapters in Books, Reports and Conference Proceedings: ChaptersThe use of contrast agents with fast field-cycling magnetic resonance imaging
Physics in Medicine and Biology, vol. 56, no. 1, pp. 105-115Contributions to Journals: ArticlesDesign and construction of an actively frequency-switchable RF coil for field-dependent Magnetisation Transfer Contrast MRI with fast field-cycling
Journal of Magnetic Resonance, vol. 207, no. 1, pp. 134-139Contributions to Journals: ArticlesA novel variable field system for field-cycled dynamic nuclear polarization spectroscopy
Journal of Magnetic Resonance, vol. 205, no. 2, pp. 202-208Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jmr.2010.04.015
Field-cycling NMR relaxometry with spatial selection
Magnetic Resonance in Medicine, vol. 63, no. 6, pp. 1698-1702Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mrm.22346
Off-resonance magnetisation transfer contrast (MTC) MRI using fast field-cycling (FFC)
Journal of Magnetic Resonance, vol. 204, no. 1, pp. 145-149Contributions to Journals: ArticlesFast field-cycling magnetic resonance imaging: Imagerie de resonance magnétique en champ cyclé
Comptes Rendus. Physique, vol. 11, no. 2, pp. 136-148Contributions to Journals: ArticlesField-cycled dynamic nuclear polarization (FC-DNP) of 14N and 15N nitroxide free radicals at low magnetic field
Journal of Physics D: Applied Physics, vol. 40, no. 18, pp. 5527-5532Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0022-3727/40/18/002
Real-time monitoring of drug-induced changes in the stomach acidity of living rats using improved pH-sensitive nitroxides and low-field EPR techniques
Journal of Magnetic Resonance, vol. 182, pp. 1-11Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jmr.2006.06.002
Sequential, Co-registered Fluorine and Proton Field-Cycled Overhauser Imaging at a Detection Field of 59 mT
Physics in Medicine and Biology, vol. 51, pp. N39-N45Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/51/3/N02
The excretion mechanism of the spin label proxyl carboxylic acid (PCA) from the rat monitored by X-band ESR and PEDRI
Magnetic Resonance in Medicine, vol. 37, no. 4, pp. 552-558Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mrm.1910370413
- [ONLINE] View publication in Scopus
Development of a 3-D, multi-nuclear continuous wave NMR imaging system
Journal of Magnetic Resonance, vol. 176, no. 2, pp. 140-150Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jmr.2005.05.022
Field-cycled PEDRI imaging of free radicals with detection at 450 mT
Magnetic Resonance Imaging, vol. 23, no. 2, pp. 175-181Contributions to Journals: ArticlesProton electron double resonance imaging of free radical distribution in environmental science applications: first results and perspectives
Magnetic Resonance Imaging, vol. 23, no. 2, pp. 183-189Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.mri.2004.11.027
Continuous Wave NMR Imaging in the Solid State
Annual Reports on NMR Spectroscopy, vol. 56, pp. 97-140Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S0066-4103(05)56002-2
Continuous wave MRI diffusion study of water in bentonite clay
Magnetic Resonance Imaging, vol. 23, pp. 317-319Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.mri.2004.11.042
Monitoring drug delivery processes by EPR and related techniques – principles and applications
Advanced Drug Delivery Reviews, vol. 57, pp. 1171-1190Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.addr.2005.01.023
In Vitro and In Vivo Measurement of pH and Thiols by EPR-Based Techniques
Antioxidants & Redox Signaling, vol. 6, pp. 667-676Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1089/152308604773934431
Spin pH and SH probes: enhancing functionality of EPR-based techniques
Spectroscopy, vol. 18, pp. 213-225Contributions to Journals: ArticlesContinuous wave MRI of heterogeneous materials
Journal of Magnetic Resonance, vol. 163, no. 2, pp. 318-324Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/S1090-7807(03)00128-9
In vivo detection of a pH-sensitive nitroxide in the rat stomach by low-field ESR-based techniques
Magnetic Resonance in Medicine, vol. 49, no. 3, pp. 558-567Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mrm.10392
Proton Electron Double Resonance Imaging (PEDRI)
In Vivo EPR (ESR): Theory and Applications. Biological Magnetic Resonance, Vol. 18, ed: L.J. Berliner, pp. 547-548, 1 pageChapters in Books, Reports and Conference Proceedings: ChaptersDevelopment of a PEDRI free-radical imager using a 0.38 T clinical MRI system
Magnetic Resonance in Medicine, vol. 47, no. 1, pp. 181-186Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mrm.10029
Proton electron double resonance imaging of the in vivo distribution and clearance of a triaryl methyl radical in mice
Magnetic Resonance in Medicine, vol. 48, pp. 530-534Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mrm.10222
Rapid imaging of free radicals in vivo using hybrid FISP field-cycled PEDRI
Physics in Medicine and Biology, vol. 47, no. 7, pp. 1091-1100Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/47/7/307
Recent Progress and Future Prospects of Free Radical Imaging by PEDRI
EPR in the 21st Century, pp. 515-523, 8 pagesChapters in Books, Reports and Conference Proceedings: ChaptersTechniques and Applications of EPR Imaging
Electron Paramagnetic Resonance; Specialist Periodical Reports, Royal Society of Chemistry, pp. 137-160, 23 pagesChapters in Books, Reports and Conference Proceedings: ChaptersContinuous-Wave MRI of Short T2 Materials
Journal of Magnetic Resonance, vol. 148, pp. 289-297Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/jmre.2000.2245
Free radical imaging
British Journal of Radiology, vol. 74, no. 885, pp. 782-784Contributions to Journals: ArticlesOptimization of field-cycled PEDRI for in vivo imaging of free radicals
Physics in Medicine and Biology, vol. 46, no. 10, pp. 2531-2544Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/46/10/302
Biological applications of spin pH probes
Cellular and Molecular Biology, vol. 46, pp. 1361-1374Contributions to Journals: ArticlesOverhauser Effect Imaging of Free Radicals
Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy. Young, I., Grant, D. (eds.)Chapters in Books, Reports and Conference Proceedings: ChaptersDetection of nitrosyl-iron complexes by proton-electron-double-resonance imaging
Free Radical Biology and Medicine, vol. 27, pp. 636-646Contributions to Journals: ArticlesLow field (10 mT) pulsed dynamic nuclear polarization
Journal of Magnetic Resonance, vol. 138, pp. 313-319Contributions to Journals: ArticlesRapid imaging of free radicals in vivo using field cycled PEDRI
Physics in Medicine and Biology, vol. 44, pp. 2867-2877Contributions to Journals: ArticlesChemically induced analgesic nephropathy in the rat monitored by proton‐electron double‐resonance imaging (PEDRI)
Magnetic Resonance in Medicine, vol. 40, no. 2, pp. 280-286Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mrm.1910400214
- [ONLINE] View publication in Scopus
Design, construction and use of a large-sample field-cycled PEDRI imager
Physics in Medicine and Biology, vol. 43, no. 7, pp. 1877-1886Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/43/7/008
- [ONLINE] View publication in Scopus
Nitroxide free radical clearance in the live rat monitored by radio- frequency CW-EPR and PEDRI
Physics in Medicine and Biology, vol. 43, no. 7, pp. 1899-1905Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/43/7/011
- [ONLINE] View publication in Scopus
Recent developments in combining LODESR imaging with proton NMR imaging
Physics in Medicine and Biology, vol. 43, no. 7, pp. 1851-1855Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/43/7/005
- [ONLINE] View publication in Scopus
The application of PEDRI to the study of free radicals in vivo
Physics in Medicine and Biology, vol. 43, no. 7, pp. 1893-1897Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/43/7/010
- [ONLINE] View publication in Scopus
A Submicrosecond Resonator and Receiver System for Pulsed Magnetic Resonance with Large Samples
Journal of Magnetic Resonance, vol. 132, no. 1, pp. 162-166Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/jmre.1998.1398
- [ONLINE] View publication in Scopus
Multimodality magnetic resonance systems for studying free radicals in vivo
Physics in Medicine and Biology, vol. 43, no. 7, pp. 1857-1861Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/43/7/006
- [ONLINE] View publication in Scopus
Magnetic resonance imaging of nitric oxide
Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 355, no. 4, pp. 146-146Contributions to Journals: AbstractsIn vivo imaging of nitroxide-free-radical clearance in the rat, using radiofrequency longitudinally detected ESR imaging
Journal of Magnetic Resonance - Series B, vol. 113, no. 3, pp. 256-261Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/jmrb.1996.0185
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Commentary: Electron spin resonance imaging studies of biological systems
Contributions to Journals: Short Survey- [ONLINE] DOI: https://doi.org/10.1259/0007-1285-69-827-983
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A combined PEDRI and CW-EPR instrument for detecting free radicals in vivo
Journal of Magnetic Resonance - Series B, vol. 113, no. 1, pp. 65-69Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/jmrb.1996.0156
- [ONLINE] View publication in Scopus
Young investigator award presentation at the 13th annual meeting of the ESMRMB, September 1996, prague a proton-electron double-resonance imaging apparatus with simultaneous multiple electron paramagnetic resonance irradiation at 10 mT
Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 4, no. 3-4, pp. 187-193Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/BF01772006
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Modification of a whole-body NMR imager into a radio frequency EPR spectrometer suitable for in vivo measurements
Measurement Science and Technology, vol. 7, no. 7, pp. 1012-1018Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0957-0233/7/7/003
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Continuous-wave NMR imaging of solids
Magnetic Resonance Materials in Physics, Biology, and Medicine, vol. 4, no. 1, pp. 77-81Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/BF01759783
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A novel multiple-tuned radiofrequency loop-gap resonator for use in PEDRI
Journal of Magnetic Resonance - Series B, vol. 110, no. 1, pp. 82-86Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/jmrb.1996.0012
Design and Optimization of an Automatic Frequency Control System for a Radiofrequency Electron Paramagnetic Resonance Spectrometer
Journal of Magnetic Resonance, Series A, vol. 117, no. 2, pp. 272-277Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/jmra.1995.0739
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An efficient birdcage resonator at 2.5 MHz using a novel multilayer self-capacitance construction technique
MAGMA Magnetic Resonance Materials in Physics, Biology, and Medicine, vol. 3, no. 3-4, pp. 163-168Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/BF01771702
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Use of a DC SQUID receiver preamplifier in a low field MRI system
IEEE Transactions on Applied Superconductivity, vol. 5, no. 2, pp. 3218-3221Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1109/77.403276
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Imaging Using the Electronic Overhauser Effect
Encyclopedia of Nuclear Magnetic Resonance. Grant, D., Harris, R. (eds.). John Wiley & Sons Ltd., pp. 2481-2486, 6 pagesChapters in Books, Reports and Conference Proceedings: ChaptersProgress toward whole-body proton-electron double-resonance imaging of free radicals
Magma: Magnetic Resonance Materials in Physics, Biology, and Medicine, vol. 2, no. 3, pp. 267-271Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/BF01705251
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Imaging Paramagnetic Species Using Radiofrequency Longitudinally Detected ESR (LODESR Imaging)
Journal of Magnetic Resonance, Series B, vol. 104, no. 3, pp. 284-288Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/jmrb.1994.1087
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EPRI and PEDRI functional imaging
Contributions to Journals: Conference Articles- [ONLINE] View publication in Scopus
The Application of Proton-Electron Double-Resonance Imaging Techniques to Proton Mobility Studies
Journal of Magnetic Resonance, Series B, vol. 104, no. 3, pp. 250-255Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1006/jmrb.1994.1082
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Proton-Electron Double-Resonance Imaging of Exogenous and Endogenous Free Radicals In-Vivo
Nuclear Magnetic Double Resonance: Proceedings of the International School of Physics "Enrico Fermi", Course CXXIII, 13-21 October 1992, Varenna, Italy (Enrico Fermi International School of Physics). Maraviglia, B. (ed.). North-Holland, pp. 485-503, 19 pagesChapters in Books, Reports and Conference Proceedings: ChaptersDC SQUID-based NMR detection from room temperature samples
Physics in Medicine and Biology, vol. 37, no. 11, pp. 2133-2138Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/0031-9155/37/11/010
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Spin-trapped hydroxyl free radicals studied at low field by Field-Cycled Dynamic Nuclear Polarization
Applied Magnetic Resonance, vol. 3, no. 5, pp. 917-925Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/BF03260122
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Production of UV-generated hydroxyl free radicals imaged by proton-electron double-resonance imaging with spin trapping
Journal of Magnetic Resonance (1969), vol. 95, no. 1, pp. 191-195Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/0022-2364(91)90337-S
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EPR spectral information obtained from field-cycled proton-electron double-resonance images
Journal of Magnetic Resonance (1969), vol. 94, no. 1, pp. 197-203Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/0022-2364(91)90310-P
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Low-field EPR measurements by field-cycled dynamic nuclear polarization
Journal of Magnetic Resonance (1969), vol. 95, no. 2, pp. 405-409Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/0022-2364(91)90230-Q
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Field-cycled proton-electron double-resonance imaging of free radicals in large aqueous samples
Journal of Magnetic Resonance (1969), vol. 84, no. 2, pp. 431-437Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/0022-2364(89)90392-2
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Proton-electron double magnetic resonance imaging of free radical solutions
Journal of Magnetic Resonance (1969), vol. 76, no. 2, pp. 366-370Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/0022-2364(88)90123-0
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Numerical design of composite radiofrequency pulses
Journal of Magnetic Resonance (1969), vol. 70, no. 1, pp. 11-20Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/0022-2364(86)90359-8
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A systematic design procedure for selective pulses in NMR imaging
Magnetic Resonance Imaging, vol. 3, no. 3, pp. 235-243Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/0730-725X(85)90352-2
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