Publications | The Institute of Medical Sciences

LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy

2024

Schwab, K., Frahm, S., Magbagbeolu, M., Horsley, D., Goatman, E., Melis, V., Theuring, F., Ishaq, A., Storey, J. M. D., Harrington, C., Wischik, C., Riedel, G.

European Journal of Pharmacology, vol. 970, 176505

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1016/j.ejphar.2024.176505
Open Access: http://aura.abdn.ac.uk/bitstream/2164/23810/1/Schwab_etal_EJP_LETC_inhibits_-Syn_VOR.pdf

Validation of positional candidates Rps6ka6 and Pou3f4 for a locus associated with skeletal muscle mass variability

2024

Lekkos, K., Bhuiyan, A. A., Albloshi, A. M., Brooks, P. M., Coate, T. M., Lionikas, A.

G3: Genes, Genomes, Genetics Mission, vol. 14, no. 5, jkae046

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1093/g3journal/jkae046
Open Access: http://aura.abdn.ac.uk/bitstream/2164/23433/1/Lekkos_etal_G3_Validation-of_Positional_VOR.pdf

CB1 Receptor Negative Allosteric Modulators as a Potential Tool to Reverse Cannabinoid Toxicity

2024

Flavin, A., Azizi, P., Murataeva, N., Yust, K., Du, W., Ross, R. A., Greig, I., Nguyen, T., Zhang, Y., Zhang, Y., Mackie, K., Straiker, A.

Molecules, vol. 29, no. 8, 1881

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.3390/molecules29081881
Open Access: http://aura.abdn.ac.uk/bitstream/2164/23368/1/Flavin_etal_M_CB_Receptor_Negative_VoR.pdf

Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model

2024

Zadrozny, M., Drapich, P., Gasiorowska-Bien, A., Niewiadomski, W., Harrington, C. R., Wischik, C. M., Riedel, G., Niewiadomska, G.

Cells, vol. 13, no. 7, 642

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.3390/cells13070642
Open Access: http://aura.abdn.ac.uk/bitstream/2164/23504/1/Zadrozny_etal_C_Neuroprotection_of_Cholinergic_VOR.pdf

Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes

2024

Mezincescu, A., Rudd, A. E., Cheyne, L., Horgan, G., Philip, S., Cameron, D., van Loon, L., Whitefield, P., Gribbin, R., Hu, M. K., Delibegovic, M., Fielding, B., Lobley, G., Thies, F., Newby, D. E., Gray, S., Henning, A., Dawson, D.

Nature Communications, vol. 15, no. 1, pp. 3690

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.6084/m9.figshare.24219934
Open Access: http://aura.abdn.ac.uk/bitstream/2164/23599/1/Mezincescu_etal_Comparison_intramyocellular_lipid_VOR.pdf
Additional Links: View publication in Scopus; https://abdn.elsevierpure.com/en/publications/32def9dd-91e5-4a39-8c0d-7bbdc7cc4c91

AI is a viable alternative to high throughput screening: a 318-target study

2024

Atomwise AIMS Program, Greig, I.

Scientific Reports, vol. 14, no. 1, pp. 7526

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41598-024-54655-z
Open Access: http://aura.abdn.ac.uk/bitstream/2164/23165/1/AIMS_etal_SR_AI_Is_A_voR.pdf
Additional Links: View publication in Scopus

Shifting our perspective on orphan G protein-coupled receptors

2024

Smith, N. J., Murray, F.

Nature Structural and Molecular Biology, vol. 31, no. 4, pp. 582-583

Contributions to Journals: Comments and Debates

Digital Object Identifier: https://doi.org/10.1038/s41594-024-01270-1
Additional Links: View publication in Scopus

Allopurinol and Blood Pressure Variability Following Ischemic Stroke and Transient Ischemic Attack: A Secondary Analysis of XILO-FIST

2024

MacDonald, A. S., McConnachie, A., Dickie, D. A., Bath, P. M., Forbes, K., Quinn, T. J., Broomfield, N. M., Dani, K. A., Doney, A. S. F., Muir, K. W., Struthers, A., Walters, M. R., Barber, M., Bhalla, A., Cameron, A., Guyler, P., Hassan, A., Kearney, M. T., Keegan, B. C., Sekaran, L., Macleod, M., Randall, M., Shaw, L., Subramanian, G., Werring, D. J., Dawson, J.

Journal of Human Hypertension, vol. 38, no. 4, pp. 307-313

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41371-024-00906-5
Open Access: http://aura.abdn.ac.uk/bitstream/2164/22914/1/Macdonald_etal_JHH_Allopurinol_And_Blood_VoR.pdf
Additional Links: View publication in Scopus

Characterizing the Neurobiological Mechanisms of Action of Exercise and Cognitive–Behavioral Interventions for Rheumatoid Arthritis Fatigue: a magnetic resonance imaging brain study

2024

Dehsarvi, A., Al-Wasity, S., Stefanov, K., Wiseman, S. J., Ralston, S., Wardlaw, J., Emsley, R., Bachmair, E., Cavanagh, J., Waiter, G., Basu, N.

Arthritis & Rheumatology, vol. 76, no. 4, pp. 522-530

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1002/art.42755
Open Access: http://aura.abdn.ac.uk/bitstream/2164/23640/2/Dehsarvi_etal_AR_Characterising_The_Neurobiological_AAM.pdf; http://aura.abdn.ac.uk/bitstream/2164/23640/1/Dehsarvi_etal_AR_Characterizing_the_Neurobiological_VOR.pdf
Additional Links: View publication in Scopus

A single-cell atlas enables mapping of homeostatic cellular shifts in the adult human breast

2024

Reed, A. D., Pensa, S., Steif, A., Stenning, J., Kunz, D. J., Porter, L. J., Hua, K., He, P., Twigger, A., Siu, A. J. Q., Kania, K., Barrow-McGee, R., Goulding, I., Gomm, J. J., Speirs, V., Jones, J. L., Marioni, J. C., Khaled, W. T.

Nature Genetics, vol. 56, no. 4, pp. 652-662

Contributions to Journals: Articles

Digital Object Identifier: https://doi.org/10.1038/s41588-024-01688-9
Open Access: http://aura.abdn.ac.uk/bitstream/2164/23344/1/Reed_etal_NG_A_Single_Cell_VOR.pdf
Additional Links: View publication in Scopus