BSc MSc PhD MIPEM
Honorary Professor
- About
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- Email Address
- r.staff@abdn.ac.uk
- Office Address
Nuclear Medicine ARI Foresterhill Aberdeen AB25 2ZD
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Roger Staff was born in London and studied physics at UEA. He moved to Aberdeen in 1988 and completed his PhD in medical physics in 1994. He has worked for the NHS since 1991 and currently leads the clinical physics imaging team at NHS-Grampian. His other interests include Intelligence and social mobility.
- Research
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Research Overview
(Since 1999) founding member of the Aberdeen 1921 & 1936 birth cohort study group with three critical responsibilities for (1) hypothesis generation and hypothesis testing; (2) brain imaging and image analysis; (3) Advance data modelling of complex databases; (Since 2003 with Taurx) the imaging the effects tau aggregation inhibition and the use of surrogate imaging measures in drug development; (Since 2008) the development of structural and temporal (fMRI) complexity measures for use in ageing and neurodegenerative disease; (Since 2012) The prognostic value of automated analysis of sequential retinal images in diabetic retinopathy. The use of external quality assurance programs in diabetic retinopathy.
- Publications
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Increased diastolic blood pressure is associated with MRI biomarkers of dementia-related brain pathology in normative ageing
Age and Ageing, vol. 47, no. 1, pp. 95-100Contributions to Journals: ArticlesLife-course determinants of cognitive reserve (CR) in cognitive aging and dementia: a systematic literature review
Aging & Mental Health, vol. 22, no. 8, pp. 915-926Contributions to Journals: ArticlesPotential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer’s Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial
Journal of Alzheimer's Disease, vol. 61, no. 1, pp. 435-457Contributions to Journals: Articles- [ONLINE] https://www.j-alz.com/vol61-1
- [ONLINE] DOI: https://doi.org/10.3233/JAD-170560
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9693/1/Potential_of_Low_Dose.pdf
Organisation of cortical thickness networks in Alzheimer’s disease and behavioural variant frontotemporal dementia across brain lobes
6th Cambridge Neuroscience SymposiumContributions to Conferences: AbstractsChildhood intelligence and personality traits neuroticism and openness contributes to social mobility: A study in the Aberdeen 1936 Birth Cohort
Personality and Individual Differences, vol. 114, pp. 206-212Contributions to Journals: ArticlesKlotho, APOEε4, cognitive ability, brain size, atrophy and survival: A study in the Aberdeen Birth Cohort of 1936
Neurobiology of Aging, vol. 55, pp. 91-98Contributions to Journals: ArticlesSexual dimorphism in changes of cortical complexity associated with cognitive decline in late life
Alzheimer's Research UKContributions to Conferences: AbstractsA brain imaging repository of normal structural MRI across the life course: Brain Images of Normal Subjects (BRAINS)
Neuroimage, vol. 144, no. Part B, pp. 299–304Contributions to Journals: ArticlesDistinct anatomical subtypes of behavioural variant frontotemporal dementia and involvement of intrinsic brain networks: a clustering study
Alzheimer Research UK (2017)Contributions to Conferences: AbstractsEfficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial
The Lancet, vol. 388, no. 10062, pp. 2873-2884Contributions to Journals: Articles