Professor John Forrester
MD FRCSE FRCSG FRCOphth
Emeritus Professor
- About
-
- Email Address
- j.forrester@abdn.ac.uk
- Office Address
Room 4.24 Institute of Medical Sciences
Foresterhill
Aberdeen
AB25 2ZD
Tel: 01224 437507
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Professor Forrester received his MD, ChB from Glasgow University, Scotland in 1970. In 1980 he received his MD also from the University of Glasgow. Between 1979-1984 he was Consultant Ophthalmologist/Clinical Lecturer in Ophthalmology at Glasgow University. In 1984 he was appointed to his current post, Cockburn Professor of Ophthalmology University of Aberdeen/Honorary Consultant Ophthalmologist, NHS Grampian.
He has over the years received 16 awards and Visiting Professorships including the London Hospital Prize for Original Research in Ophthalmology in 1977, the Duke Elder Medal and the Ida Mann Medal in 1991. He received the Spinoza Professorship in Amsterdam in 1998 and the Kimura Lectureship as Visiting Professor (UCSF) University of California, San Francisco in 2004.
His main areas of research are Diabetic Retinopathy, Angiogenesis, Endothelial Cell Function, Ocular Immunology, Uveitis, Autoimmune Disease, Imaging in Ophthalmology, Wound Healing and Corneal Transplantation and has published over 260 papers.
He is a Fellow of the Royal College of Surgeons of Edinburgh and Glasgow, Royal College of Ophthalmologists, Physicians of Edinburgh, Academy of Medical Sciences and the Royal Society of Edinburgh.
He was Chairman of the RCOphth Medical Ophthalmology Training Sub-Committee and the RCOphth Diabetic Retinopathy Guidelines Committee and a member of the MRC Advisory Board. He was previously Editor-in-Chief of the British Journal of Ophthalmology 1992-2000. He is currently an Editorial Board member of the British Journal of Ophthalmology, European Journal of Ophthalmology and Current Eye Research.
- Publications
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Page 1 of 5 Results 1 to 50 of 223
Colitis in a transgenic mouse model of autoimmune uveitis may be induced by neoantigen presentation in the bowel
Scientific Reports, vol. 13, 1256Contributions to Journals: ArticlesImmune Privilege Furnishes a Niche for Latent Infection
Frontiers in Ophthalmology, vol. 2, 869046Contributions to Journals: ArticlesA Role for Folate in Microbiome-Linked Control of Autoimmunity
Journal of Immunology Research, vol. 2021, 9998200Contributions to Journals: Review articlesLow-dose 2-Deoxy Glucose Stabilises Tolerogenic Dendritic Cells and Generates Potent in vivo Immunosuppressive Effects
Cellular and Molecular Life Sciences, vol. 78, no. 6, pp. 2857-2876Contributions to Journals: ArticlesImmune Privilege: the Microbiome and Uveitis
Frontiers in Immunology, vol. 11, 608337Contributions to Journals: ArticlesThe Role of Inflammation in Diabetic Retinopathy
Frontiers in Immunology, vol. 11, no. 20, pp. 10319-10329Contributions to Journals: ArticlesTreatment with FoxP3+ Antigen-Experienced T Regulatory Cells Arrests Progressive Retinal Damage in a Spontaneous Model of Uveitis
Frontiers in Immunology, vol. 11, pp. 1-17Contributions to Journals: ArticlesActivation of dendritic cells by crosslinked collagen hydrogels (artificial corneas) varies with their composition
Journal of Tissue Engineering and Regenerative Medicine, vol. 13, no. 9, pp. 1528-1543Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/term.2903
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14733/1/Molzer_et_al_JTissueEngRegenMed_activation_of_dendritic_AAM.pdf
- [ONLINE] View publication in Mendeley
- [ONLINE] https://abdn.pure.elsevier.com/en/en/researchoutput/activation-of-dendritic-cells-by-crosslinked-collagen-hydrogels-artificial-corneas-varies-with-their-composition(4cd96efc-d372-41ea-b51f-34b735a0a7da).html
TGF‐β1‐activated type 2 dendritic cells promote wound healing and induce fibroblasts to express tenascin c following corneal full‐thickness hydrogel transplantation
Journal of Tissue Engineering and Regenerative Medicine, vol. 13, no. 9, pp. 1507-1517Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/term.2853
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14769/1/M_lzer_et_al_TGF_Beta1_AAM.pdf
- [ONLINE] View publication in Mendeley
- [ONLINE] https://abdn.pure.elsevier.com/en/en/researchoutput/tgf1activated-type-2-dendritic-cells-promote-wound-healing-and-induce-fibroblasts-to-express-tenascin-c-following-corneal-fullthickness-hydrogel-transplantation(96c6cff1-c99e-4dc2-9c94-7f207f2fc4dc).html
- [ONLINE] View publication in Scopus
Retinoic acid‐induced autoantigen‐specific type 1 regulatory T cells suppress autoimmunity
EMBO reports, vol. 20, no. 3, e47121Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.15252/embr.201847121
- [ONLINE] View publication in Scopus
Transmission Electron Microscopy Data on drusen-like deposits in the retinal degeneration sTg-IRBP: HEL mouse model
Data in brief, vol. 22, pp. 140-144Contributions to Journals: ArticlesPolarized retinal pigment epithelium generates electrical signals that diminish with age and regulate retinal pathology
Journal of Cellular and Molecular Medicine, vol. 22, no. 11, pp. 5552-5564Contributions to Journals: ArticlesThe atypical chemokine receptor-2 does not alter corneal graft survival but regulates early stage of corneal graft induced lymphangiogenesis
Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 256, no. 10, pp. 1875-1882Contributions to Journals: ArticlesPartial retinal photoreceptor loss in a transgenic mouse model associated with reduced levels of interphotoreceptor retinol binding protein (IRBP, RBP3)
Experimental Eye Research, vol. 172, pp. 54-65Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.exer.2018.03.020
Autoimmunity, Autoinflammation, and Infection in Uveitis
American Journal of Ophthalmology, vol. 189, pp. 77-85Contributions to Journals: ArticlesEndogenous bioelectric currents promote differentiation of the mammalian lens
Journal of Cellular Physiology, vol. 233, no. 3, pp. 2202-2212Contributions to Journals: ArticlesMesenchymal stem cell therapy for retro-corneal membrane - A clinical challenge in full-thickness transplantation of biosynthetic corneal equivalents
Acta Biomaterialia, vol. 64, pp. 346-356Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.actbio.2017.10.011
In-vivo evidence that high mobility group box 1 exerts deleterious effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and Parkinson's disease which can be attenuated by glycyrrhizin
Neurobiology of Disease, vol. 91, pp. 59-68Contributions to Journals: ArticlesHigh-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection
Investigative Ophthalmology & Visual Science, vol. 57, no. 4, pp. 1578-1587Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1167/iovs.15-17894
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5893/1/i1552_5783_57_4_1578.pdf
High-risk corneal allografts: A therapeutic challenge
World Journal of Transplantation, vol. 6, no. 1, pp. 10-27Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.5500/wjt.v6.i1.10
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5845/1/WJT_6_10.pdf
Evidence for a role of adaptive immune response in the disease pathogenesis of the MPTP mouse model of Parkinson’s disease
Glia, vol. 64, no. 3, pp. 386-395Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/glia.22935
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5172/4/Martin_et_al_2016_Glia.pdf
The critical points in induction of experimental autoimmune uveitis
Biomedical Papers of the Medical Faculty of the University PalackÝ, Olomouc, Czechoslovakia, vol. 160, no. 1, pp. 140-142Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.5507/bp.2015.056
Retinal Pigment Epithelial Cell Apoptosis is Influenced by a Combination of Macrophages and Soluble Mediators Present in Age-Related Macular Degeneration
Current Eye Research, vol. 41, no. 9, pp. 1235-1244Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3109/02713683.2015.1109129
A key role for PTP1B in dendritic cell maturation, migration and T cell activation
Journal of Molecular Cell Biology, vol. 7, no. 6, pp. 517-528Contributions to Journals: ArticlesDendritic cells and the extracellular matrix: A challenge for maintaining tolerance/homeostasis
World Journal of Immunology, vol. 5, no. 3, pp. 113-130Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.5411/wji.v5.i3.113
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/5261/1/113.pdf
Murine pattern recognition receptor dectin-1 is essential in the development of experimental autoimmune uveoretinitis
Molecular Immunology, vol. 67, no. 2 B, pp. 398-406Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.molimm.2015.07.002
Fundus Autofluorescence in Posterior Uveitis
Fundus Autofluorescence. Lois, N., Forrester, J. V. (eds.). 2 edition. Lippincott Williams & Wilkins, pp. 262-272, 11 pagesChapters in Books, Reports and Conference Proceedings: ChaptersAssessing the painful, uninflamed eye in primary care
BMJ, vol. 351, h3216Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.h3216
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4786/1/bmj.h3216.full.pdf
Treatment of diffuse subretinal fibrosis uveitis with rituximab
British Journal of Ophthalmology, vol. 99, no. 2, pp. 153-154Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bjophthalmol-2013-304686
Local targeting of the CD200-CD200R axis does not promote corneal graft survival
Experimental Eye Research, vol. 130, pp. 1-8Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.exer.2014.11.006
Behavioural characterization of the sub-acute and acute MPTP mouse model of Parkinson’s disease
BNA 2015 Festival of NeuroscienceContributions to Conferences: PostersCathelicidin LL-37 and HSV-1 Corneal Infection: Peptide Versus Gene Therapy
Translational vision science & technology, vol. 3, no. 3, pp. 4Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1167/tvst.3.3.4
Soluble antigen traffics rapidly and selectively from the corneal surface to the eye draining lymph node and activates T cells when codelivered with CpG oligonucleotides
Journal of Leukocyte Biology, vol. 95, no. 3, pp. 431-440Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1189/jlb.0612294
Myeloid-Cell Protein Tyrosine Phosphatase-1B Deficiency in Mice Protects Against High-Fat Diet and Lipopolysaccharide-Induced Inflammation, Hyperinsulinemia, and Endotoxemia Through an IL-10 STAT3-Dependent Mechanism
Diabetes, vol. 63, no. 2, pp. 456-470Contributions to Journals: ArticlesBehavioural characterization of the sub-acute MPTP mouse model of Parkinson’s disease
Scottish Neuroscience Group meeting 2014Contributions to Conferences: PostersCrosslinked collagen hydrogels as corneal implants: effects of sterically bulky vs. non-bulky carbodiimides as crosslinkers
Acta Biomaterialia, vol. 9, no. 8, pp. 7796–7805Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.actbio.2013.04.014
The high-risk corneal regraft model: a justification for tissue matching in humans
Transplant International, vol. 26, no. 4, pp. 453-461Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/tri.12055
Uveitis in mouse and man
International Reviews of Immunology, vol. 32, no. 1, pp. 76-96Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3109/08830185.2012.747524
Tumor necrosis factor polymorphisms associated with tumor necrosis factor production influence the risk of idiopathic intermediate uveitis
Molecular vision, vol. 19, pp. 184-195Contributions to Journals: ArticlesMHCII ablation attenuates reactive gliosis and alters cytokine responses in the MPTP-model of Parkinson’s disease
AD/PD ConferenceContributions to Conferences: PostersSympathetic Ophthalmia
Complications of Vitreo-Retinal Surgery: How to prevent them, how to solve them. Wong, D., Lois, N. (eds.). Lippincott Williams & WilkinsChapters in Books, Reports and Conference Proceedings: ChaptersBiosynthetic Alternatives to Human Donor Tissue
Copeland and Afshari's Principles and Practice of Cornea. Copeland, R. A., Afshari, N. (eds.). Jaypee Brothers Medical Publishers, pp. chapter 66Chapters in Books, Reports and Conference Proceedings: ChaptersIntravenous ‘pulse’ Methylprednisolone for the Treatment of Inflammatory Cystoid Macular Oedema
British Journal of Ophthalmology, vol. 96, no. 12, pp. 1531-1533Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bjophthalmol-2012-301777
CD11b(+) Bone Marrow-Derived Monocytes Are the Major Leukocyte Subset Responsible for Retinal Capillary Leukostasis in Experimental Diabetes in Mouse and Express High Levels of CCR5 in the Circulation
American Journal of Pathology, vol. 181, no. 2, pp. 719-727Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ajpath.2012.04.009
A role for PP1/NIPP1 in steering migration of human cancer cells
PloS ONE, vol. 7, no. 7, e40769Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0040769
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3492/1/A_role_for_PP1.pdf
Regenerative approaches as alternatives to donor allografting for restoration of corneal function
The Ocular Surface, vol. 10, no. 3, pp. 170-183Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jtos.2012.04.004
A Randomized Trial of Tacrolimus versus Tacrolimus and Prednisone for the Maintenance of Disease Remission in Noninfectious Uveitis
Ophthalmology, vol. 119, no. 6, pp. 1223-1230Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ophtha.2011.12.030
Persistent inflammation subverts thrombospondin-1-induced regulation of retinal angiogenesis and is driven by CCR2 ligation
American Journal of Pathology, vol. 180, no. 1, pp. 235-245Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ajpath.2011.09.020
TLR9 ligand CpG-ODN applied to the injured mouse cornea elicits retinal inflammation
American Journal of Pathology, vol. 180, no. 1, pp. 209-220Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ajpath.2011.09.041
MHCII and the innate immune system: what is their role in Parkinson's disease?
Society for NeuroscienceContributions to Conferences: Posters