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The Institute of Medical Sciences

Professor David J. Blackbourn

Professor David J. Blackbourn
Professor David J. Blackbourn
Professor David J. Blackbourn

Professor of Virology, Interim Head of School

Accepting PhDs

About
Office Address
Institute of Medical Sciences
Foresterhill Campus
Ashgrove Road West
AB25 2ZD

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School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

David’s PhD (1990) is in molecular genetics and he has worked on different aspects of virology and immunology including in the USA, where he worked at the University of California (UC) for nine years on HIV and Kaposi’s sarcoma herpesvirus (KSHV), including six years with Dr Jay A. Levy. 

David’s research more recently has focused on viruses that are responsible for causing cancer.  In particular, he concentrates on how such viruses hide from the immune system.  By studying human viruses that have evolved with their host for at least 25 million years, David believes that unique insight into the workings of the immune system can be gained.  This knowledge can then be put to good use to treat immune system disorders.  Techniques include a combination of molecular virology and immunology.

He has either authored or co-authored over £8m in funded research grant awards and published over 75 manuscripts that have been cited over 5000 times (Google Scholar), with two papers cited over 600 times each and a further three papers cited over 200 times each.

David returned to the UK from the USA in 1999 to his first lectureship at the University of Glasgow.  In 2005 he moved to the University of Birmingham and received his Chair there in 2010.  He moved to the University of Surrey to be Head of the Department of Microbial Sciences in August 2013 and in December of that year was appointed Head of the School of Biosciences and Medicine, consisting of four departments, a clinical trials faciility and a clinical trials unit.  He held that position for eight years. 

David is proud to have been appointed Director of the Institute of Medical Sciences at the University of Aberdeen, commencing January 2022.

ORCID ID: https://orcid.org/0000-0002-6703-4497

External Memberships

David is one of three Founding Directors of Ducentis Biotherapeutics (www.ducentisbio.com) established in 2015 to exploit his research findings to create next generation anti-inflammatory and autoimmune medicines.  David serves as a non-executive board member for Ducentis, which has secured c£4m in start-up funding, including from LifeArc.

He is one of three Editors-in-Chief for FEMS Microbiology Reviews (https://academic.oup.com/femsre), which publishes invited comprehensive and authoritative reviews on all aspects of microbiology from leading authors.  FEMS Microbiology Reviews ranked 6th of 134 Microbiology journals in the 2020 Journal Citation Reports.

Latest Publications

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Research

Research Areas

Accepting PhDs

I am currently accepting PhDs in Biomedical Sciences.

Please get in touch if you would like to discuss your research ideas further.

Biomedical Sciences

Accepting PhDs
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Publications

Page 2 of 2 Results 51 to 79 of 79

  • The restricted cellular host range of human herpesvirus 8

    Blackbourn, D. J., Lennette, E., Klencke, B., Moses, A., Chandran, B., Weinstein, M., Glogau, R. G., Witte, M. H., Dennis, W. L., Kutzkey, T., Herndier, B., Levy, J. A.
    AIDS, vol. 14, no. 9, pp. 1123-1133
    Contributions to Journals: Articles

  • Suppression of human immunodeficiency virus type 1 replication by a soluble factor produced by CD8 + lymphocytes from HIV-2-infected baboons

    Locher, C. P., Blackbourn, D. J., Levy, J. A.
    Immunology Letters, vol. 66, no. 1-3, pp. 151-157
    Contributions to Journals: Articles

  • Increased human herpesvirus 8 seroprevalence in young homosexual men who have multiple sex contacts with different partners

    Blackbourn, D. J., Osmond, D., Levy, J. A., Lennette, E. T.
    Journal of Infectious Diseases, vol. 179, no. 1, pp. 237-239
    Contributions to Journals: Articles

  • Human immunodeficiency virus-2 infection in baboons is an animal model for human immunodeficiency virus pathogenesis in humans

    Locher, C. P., Barnett, S. W., Herndier, B. G., Blackbourn, D. J., Reyes-Terán, G., Murthy, K. K., Brasky, K. M., Hubbard, G. B., Reinhart, T. A., Haase, A. T., Levy, J. A.
    Archives of Pathology and Laboratory Medicine, vol. 122, no. 6, pp. 523-533
    Contributions to Journals: Articles

  • Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells

    Renne, R., Blackbourn, D., Whitby, D., Levy, J., Ganem, D.
    Journal of Virology, vol. 72, no. 6, pp. 5182-5188
    Contributions to Journals: Articles

  • Transient virus infection and pathogenesis of a new HIV type 2 isolate, UC12, in baboons

    Locher, C. P., Blackbourn, D. J., Herndier, B. G., Reyes-Terán, G., Barnett, S. W., Murthy, K. K., Levy, J. A.
    AIDS Research and Human Retroviruses, vol. 14, no. 1, pp. 79-82
    Contributions to Journals: Articles

  • CD8 cell noncytotoxic antiviral activity in human immunodeficiency virus-infected and -uninfected children

    Levy, J. A., Hsueh, F., Blackbourn, D. J., Wara, D., Weintrub, P. S.
    Journal of Infectious Diseases, vol. 177, no. 2, pp. 470-472
    Contributions to Journals: Articles

  • Human herpesvirus 8 detection in nasal secretions and saliva

    Blackbourn, D. J., Lennette, E. T., Ambroziak, J., Mourich, D. V., Levy, J. A.
    Journal of Infectious Diseases, vol. 177, no. 1, pp. 213-216
    Contributions to Journals: Articles

  • Infectious human herpesvirus 8 in a healthy North American blood donor

    Blackbourn, D. J., Ambroziak, J., Lennette, E., Adams, M., Ramachandran, B., Levy, J. A.
    Lancet, vol. 349, no. 9052, pp. 609-611
    Contributions to Journals: Articles

  • CD8+ cells from HIV-2-infected baboons control HIV replication

    Blackbourn, D. J., Locher, C. P., Ramachandran, B., Barnett, S. W., Murthy, K. K., Carey, K. D., Brasky, K. M., Levy, J. A.
    AIDS, vol. 11, no. 6, pp. 737-746
    Contributions to Journals: Articles

  • Human herpesvirus 8 in semen and prostate

    Blackbourn, D. J., Levy, J. A.
    AIDS, vol. 11, no. 2, pp. 249-250
    Contributions to Journals: Editorials

  • Superinfection with human immunodeficiency virus type 2 can reactivate virus production in baboons but is contained by a CD8 T cell antiviral response

    Locher, C. P., Blackbourn, D. J., Barnett, S. W., Murthy, K. K., Cobb, E. K., Rouse, S., Greco, G., Reyes-Terán, G., Brasky, K. M., Carey, K. D., Levy, J. A.
    Journal of Infectious Diseases, vol. 176, no. 4, pp. 948-959
    Contributions to Journals: Articles

  • Suppression of HIV replication by lymphoid tissue CD8+ cells correlates with the clinical state of HIV-infected individuals

    Blackbourn, D. J., Mackewicz, C. E., Barker, E., Hunt, T. K., Herndier, B., Haase, A. T., Levy, J. A.
    Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 23, pp. 13125-13130
    Contributions to Journals: Articles

  • Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients

    Lennette, E. T., Blackbourn, D. J., Levy, J. A.
    Lancet, vol. 348, no. 9031, pp. 858-861
    Contributions to Journals: Articles

  • Molecular cloning of the human immunodeficiency virus subtype 2 strain HIV-2(UC2)

    Barnett, S. W., Legg, H. S., Sun, Y., Klinger, J., Blackbourn, D. J., Locher, C. P., Levy, J. A.
    Virology, vol. 222, no. 1, pp. 257-261
    Contributions to Journals: Articles

  • Susceptibility of peripheral blood mononuclear cells from gorillas, orangutans and baboons to diverse HIV isolates

    Locher, C. P., Blackbourn, D. J., Castro, B. A., Brasky, K. M., Levy, J. A.
    AIDS, vol. 10, no. 12, pp. 1438-1440
    Contributions to Journals: Letters

  • CD8+ T cells suppress human immunodeficiency virus replication by inhibiting viral transcription

    Mackewicz, C. E., Blackbourn, D. J., Levy, J. A.
    Proceedings of the National Academy of Sciences of the United States of America, vol. 92, no. 6, pp. 2308-2312
    Contributions to Journals: Articles

  • Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients

    Ambroziak, J. A., Blackbourn, D. J., Herndier, B. Q., Glogau, R. G., Gullett, J. H., McDonald, A. R., Lennette, E. T., Levy, J. A.
    Science, vol. 268, no. 5210, pp. 582-583
    Contributions to Journals: Comments and Debates

  • Suppression of HIV Replication by CD8+ Cell Clones Derived from HIV-Infected and Uninfected Individuals

    Hsueh, F. W., Walker, C. M., Blackbourn, D. J., Levy, J. A.
    Cellular Immunology, vol. 159, no. 2, pp. 271-279
    Contributions to Journals: Articles

  • Inhibition of simian immunodeficiency virus (SIV) replication by CD8 + cells of SIV‐infected rhesus macaques: Implications for immunopathogenesis

    Blackbourn, D. J., Chuang, L. F., Killam, K. F., Chuang, R. Y.
    Journal of Medical Primatology, vol. 23, no. 6, pp. 343-354
    Contributions to Journals: Articles

  • 60th forum in immunology: General discussion

    Blackbourn, D. J.
    Research in Immunology, vol. 145, no. 8-9, pp. 714-724 (715)
    Contributions to Journals: Articles

  • Emergence of antigenic variants of simian immunodeficiency virus (SIVmac) in a seronegative macaque SIVmac239 infection

    Chuang, L. F., Blackbourn, D. J., Chuang, A. J., Killam, K. F., Liu, X., Li, Y., Kung, H. F., Chuang, R. Y.
    Cellular and Molecular Biology Research, vol. 40, no. 7-8, pp. 661-669
    Contributions to Journals: Articles

  • Human CD8+ cell non-cytolytic anti-HIV activity mediated by a novel cytokine

    Blackbourn, D. J., Mackewicz, C., Barker, E., Levy, J. A.
    Research in Immunology, vol. 145, no. 8-9, pp. 653-659
    Contributions to Journals: Articles

  • Th1/Th2 cytokines in AIDS: sorting out the confusion

    Blackbourn, D. J.
    Research in Immunology, vol. 145, no. 8-9, pp. 715
    Contributions to Journals: Comments and Debates

  • A Simple Method to Distinguish Between Simian Immunodeficiency Virus Isolates by Restriction Analysis of PCR Products

    Blackbourn, D. J., Sutjipto, S., Doi, R. H., Chuang, R. Y.
    DNA and Cell Biology, vol. 12, no. 7, pp. 617-622
    Contributions to Journals: Articles

  • Simian opioid dependency, immune function and SAIDS

    Chuang, R. Y., Blackbourn, D. J., Chuang, L. F., Liu, Y., Killam, K. F.
    NIDA Research Monograph Series, no. 132, pp. 71
    Contributions to Journals: Articles

  • Detection of simian immunodeficiency virus RNA from infected rhesus macaques by the polymerase chain reaction

    Blackbourn, D. J., Chuang, L. F., Sutjipto, S., Killam, K. F., McCready, P. M., Doi, R. H., Li, Y., Chuang, R. Y.
    Journal of Virological Methods, vol. 37, no. 2, pp. 109-117
    Contributions to Journals: Articles

  • Effects of in vivo and in vitro administration of morphine sulfate upon rhesus macaque polymorphonuclear cell phagocytosis and chemotaxis

    Liu, Y., Blackbourn, D. J., Chuang, L. F., Killam, K. F., Chuang, R. Y.
    Journal of Pharmacology and Experimental Therapeutics, vol. 263, no. 2, pp. 533-539
    Contributions to Journals: Articles

  • Evaluation of anti-SIV potential of anti-neoplastic anthracyclines

    Wuu, J., Chuang, L. F., Blackbourn, D. J., Killam, K. F., Israel, M., Chuang, R. Y.
    Proceedings of the Western Pharmacology Society, vol. 35, pp. 141-146
    Contributions to Journals: Articles
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