Dr Carl Counsell

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Dr Carl Counsell
Dr Carl Counsell
Dr Carl Counsell

MRCP, MSc, MD

Reader (Clinical)

About
Email Address
carl.counsell@abdn.ac.uk
Office Address

Room 1:009, Polwarth Building Division of Applied Health Sciences University of Aberdeen Foresterhill Aberdeen AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Carl is a clinical reader and honorary consultant in neurology.  He graduated in medicine from Cambridge University in 1988, did his early postgraduate medical training in London, Newcastle and Falkirk and then trained in neurology, stroke and epidemiology in Edinburgh.  He spent a year in Melbourne where he specialised in movement disorders before taking up his present post in 2001.  A committed Christian, he would like to have more time to serve in his church and develop his interests in Fairtrade and conservation. 

Latest Publications

View My Publications

Research

Research Overview

Carl is a consultant neurologist with subspecialty interest in movement disorders.  His main research interests are in evidence-based medicine and broader aspects of clinical epidemiology such as incidence and prognostic studies, particularly in relation to Parkinson's disease, other movement disorders and stroke.  His team have established several cohorts of parkinsonian patients for long-term follow-up and supported a number of non-industry sponsored clinical trials and Cochrane reviews, whilst also trying to promote multidisciplinary neurology research in Aberdeen. 

Research Specialisms

  • Clinical Medicine

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Current Research

The PINE study: a population-based incidence cohort of people with Parkinson's disease and other parkinsonian disorders, along with their carers and controls who are being followed up lifelong to establish long-term prognosis.

The Parkinson's Incidence Cohorts Collaboration:  an individual patient data meta-analysis of all population- based incidence cohorts of Parkinson's disease to assess prognosis and allow prognostic modelling.     

The Scottish PSP/CBD prevalence cohort:  a cohort of people with two related Parkinson's plus disorders,  Progressive Supranuclear Palsy and Corticobasal Degeneration as well as Parkinson's disease controls, to assess diagnostic and care pathways and prognosis.  

 

Past Research

Cochrane systematic reviews of randomised trials in stroke care and Parkinson's disease

Prognostic modelling in acute stroke

Incidence of Parkinson's disease and other parkinsonian disorders in North-East Scotland 

Prevalence of multiple sclerosis in North-East Scotland and northern isles

Randomised trial of physiotherapy for cervical dystonia

 

Knowledge Exchange

Member of Parkinson's Excellence Network

Collaborations

Cochrane Collaboration Stroke Review Group, Professors Charles Warlow and Peter Sandercock, University of Edinburgh, UK, 1993-98.

Scottish Audit of Intracranial Vascular Malformations, Professor Rustam Al-Shahi Salman, University of Edinburgh, UK, 2002-2014. 

PDMED trial, Professor Carl Clarke, University of Birmingham, UK, 2004-2020.

Clinical trial methods in neurodegenerative diseases, Professor John Zajicek, University of Plymouth, UK, 2009-2014. 

PDCOMM trial, Professor Sackley, University of Nottingham, UK, 2016-2023.

NICE technology appraisals for multiple sclerosis, Universities of Warwick and Exeter, UK, 2016-2022 

Parkinson's Incidence Cohorts Collaboration, Professor Tysnes, Dr Guido Alves, Professor Lars Forsgren, Dr Caroline Williams-Gray, Dr Alison Yarnall, Universities of Stavanger (Norway), Umea (Sweden), Cambridge (UK) and Newcastle (UK), 2018 ongoing 

PD Connect exercise trial, Julie Jones, Robert Gordon University, Aberdeen, UK, 2019-2022 

 

Supervision

Dr Kate Taylor (MD), 2002-06, Incidence and prognosis of parkinsonism in north-east Scotland: a pilot study.

Clare Harris (MSc), 2006-08, PINE participants attitudes to brain donation. 

Dr Robert Caslake (PhD), 2006-11, Incidence and short-term prognosis of Parkinson's disease and other parkinsonian disorders in north-east Scotland.

Dr Elizabeth Visser (MD), 2009-13, Prevalence of multiple sclerosis in northern Scotland.

Dr David McGhee (PhD), 2009-13, Improving clinical trial design in neurodegenerative diseases.

Dr Angus Macleod (PhD), 2012-15, Predicting mortality and dependency in Parkinson's disease.

Dr Diane Swallow (PhD), 2016-21, Assessing diagnostic pathways in progressive supranuclear palsy and corticobasal degeneration.

Funding and Grants

Research funding has been obtained from:

Parkinson’s UK, Scottish Chief Scientist Office, BMA Doris Hillier award, RS Macdonald Trust, BUPA Foundation, NHS Grampian endowments, Dystonia Society, National Institute for Health Research.  

Teaching

Teaching Responsibilities

Lectures and clinical teaching of neurology for medical and dental students.

Supervising medical student elective and MSc projects 

Non-course Teaching Responsibilities

Regent to medical students

Publications

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  • Fibrinogen-Depleting Agents for Acute Ischemic Stroke

    Liu, M., Counsell, C., Zhao, X. L., Wardlaw, J.
    Stroke, vol. 36, pp. 173-174
    Contributions to Journals: Editorials
  • Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke

    Sandercock, P., Counsell, C. E., Stobbs, S. L.
    Stroke, vol. 36, no. 9, pp. 2045-2046
    Contributions to Journals: Editorials
  • Monoamine oxidase B inhibitors for early Parkinson's disease

    Macleod, A. D., Counsell, C. E., Ives, N., Stowe, R.
    Cochrane Database of Systematic Reviews, no. 3, CD004898
    Contributions to Journals: Articles
  • Screening for undiagnosed parkinsonism among older people in general practice

    Taylor, K. S. M., Counsell, C. E., Gordon, J. C., Harris, C. E.
    Age and Ageing, vol. 34, pp. 501-504
    Contributions to Journals: Articles
  • The early prognosis for death and haemorrhage for adults with arteriovenous malformations (AVMs) of the brain: prospective, population-based study.

    Al-Shahi, R., Bhattacharya, J. J., Counsell, C. E., Papanastassiou, V., Roberts, R. C., Sellar, R. J., Warlow, C.
    Journal of Neurological Sciences, vol. 238, no. SUPPL 1
    Contributions to Journals: Abstracts
  • Anticoagulants for Acute Ischemic Stroke

    Sandercock, P., Gubitz, G., Counsell, C. E.
    Stroke, vol. 35, no. 12, pp. 2916-2917
    Contributions to Journals: Editorials
  • Prevalence of abnormal neurological signs in community-dwelling older people

    Foy, J., Counsell, C. E., Seymour, D. G., Lemmon, H.
    Age and Ageing, vol. 33, no. Suppl 2, pp. ii36
    Contributions to Journals: Abstracts
  • Monoamine oxidase type B inhibitors in early Parkinson’s disease: meta-analysis of 17 randomised trials involving 3525 patients

    Ives, N. J., Stowe, R. L., Marro, J., Counsell, C. E., MacLeod, A., Clarke, C. E., Gray, R., Wheatley, K.
    British Medical Journal, vol. 329, no. 7466, pp. 593-596
    Contributions to Journals: Articles
  • Maximising patient consent for video recording

    Taylor, K. S. M., Counsell, C. E., Gordon, J. C., Harris, C. E.
    Movement Disorders, vol. 19, no. 9, pp. 1116
    Contributions to Journals: Letters
  • Movement Disorder Society Task Force Report on the Hoehn and Yahr staging scale [HY]: status and recommendations

    Goetz, C. G., Poewe, W., Rascol, O., Sampaio, C., Stebbins, G. T., Counsell, C. E., Giladi, N., Holloway, R. G., Moore, C. G., Wenning, G. K., Yahr, M. D., Seidl, L., Movement Disorder Society Task Force on Rating Scales for Parkinson's Disease
    Movement Disorders, vol. 19, no. 9, pp. 1020-1028
    Contributions to Journals: Articles
  • Meta-analysis of selegiline trials in early Parkinson's disease

    Stowe, R. L., Ives, N. J., Counsell, C. E., Clarke, C. E., Marro, J., Gray, R., Wheatley, K.
    Autumn Meeting of the Association of British Neurologists, pp. 804-804
    Contributions to Journals: Abstracts
  • The role of two simple questions in identifying elderly patients with undiagnosed parkinsonism

    Counsell, C. E., Gordon, J. C., Harris, C. E.
    Autumn Meeting of the Association of British Neurologists, pp. 805-805
    Contributions to Journals: Abstracts
  • The presentation of adults with arteriovenous malformations of the brain: prospective, population-based study

    Al-Shahi, R., Bhattacharya, J. J., Counsell, C. E., Papanastassiou, V., Ritchie, V. R., Roberts, R., Sellar, R. J., Warlow, C., SIVMS Collaborators
    Autumn Meeting of the Association of British Neurologists, pp. 522-522
    Contributions to Journals: Abstracts
  • Predicting functional outcome in acute stroke: comparison of a simple six variable model with other predictive systems and informal clinical prediction

    Counsell, C., Dennis, M., McDowall, M.
    Journal of Neurology, Neurosurgery & Psychiatry, vol. 75, no. 3, pp. 401-405
    Contributions to Journals: Articles
  • A comparative study of rasagiline versus placebo or entacapone as adjunt to levodopa in Parkinson's disease (PD) patients with motor fluctuations (the LARGO Study)

    Rascol, O., Brooks, D. J., Melamed, E., Oertel, W. H., Poewe, W., Stocchi, F., Tolosa, E., Counsell, C. E., LARGO Study Group
    Movement Disorders, vol. 19, no. SUPPL 9, pp. S200-S201
    Contributions to Journals: Articles
  • A pilot study of the incidence and long-term outcome of Parkinson’s disease and other parkinsonian syndromes in North-East Scotland

    Taylor, K. S. M., Counsell, C. E., Gordon, J. C., Harris, C. E.
    Movement Disorders, vol. 19, no. Suppl 9, pp. S161-S162
    Contributions to Journals: Articles
  • MAOBI therapy in early Parkinson’s disease: a systematic review of randomised controlled trials

    Stowe, R. L., Ives, N. J., Counsell, C. E., Clarke, C. E., Gray, R., Wheatley, K.
    Movement Disorders, vol. 19, no. Suppl 9
    Contributions to Journals: Articles
  • Rasagiline treatment can improve freezing of gait in advanced Parkinson's disease; a prospective randomised double blind, placebo and entacapone controlled study.

    Giladi, N., Rascol, O., Brooks, D. J., Melamed, E., Oertel, W. H., Poewe, W., Stocchi, F., Tolosa, E., Counsell, C. E., LARGO Study Group
    Movement Disorders, vol. 19, no. SUPPL 9
    Contributions to Journals: Articles
  • Spatial channels of visual processing in cortical blindness

    Sahraie, A., Trevethan, C. T., Weiskrantz, L., Olson, J., MacLeod, M. J., Murray, A. D., Dijkhuizen, R. S., Counsell, C. E., Coleman, R.
    European Journal of Neuroscience, vol. 18, no. 5, pp. 1189-1196
    Contributions to Journals: Articles
  • Fibrinogen depleting agents for acute ischaemic stroke (updated Cochrane Review)

    Liu, M., Counsell, C., Zhao, X., Wardlaw, J. M.
    Cochrane Database of Systematic Reviews, no. 3, CD000091
    Contributions to Journals: Articles
  • Reliability of the variables in a new set of models that predict outcome after stroke

    Weir, N. U., Counsell, C. E., McDowall, M., Gunkel, A., Dennis, M. S.
    Journal of Neurology, Neurosurgery & Psychiatry, vol. 74, no. 4, pp. 447-451
    Contributions to Journals: Articles
  • Problems with UK government’s risk sharing scheme for assessing drugs for multiple sclerosis

    Sudlow, C. L. M., Counsell, C. E.
    British Medical Journal, vol. 326, pp. 388-392
    Contributions to Journals: Articles
  • Performance of a statistical model to predict stroke outcome in the context of a large, simple, randomized, controlled trial of feeding

    Counsell, C., Dennis, M. S., Lewis, S., Warlow, C., FOOD Trial Collaboration
    Stroke, vol. 34, no. 1, pp. 127-133
    Contributions to Journals: Articles
  • Systematic review of incidence studies of Parkinson’s disease

    Twelves, D., Perkins, K. S. M., Counsell, C. E.
    Movement Disorders, vol. 18, no. 1, pp. 19-31
    Contributions to Journals: Articles
  • Anticoagulants for preventing recurrence following presumed non-cardioembolic ischaemic stroke or transient ischaemic attack (updated Cochrane Review).

    Sandercock, P., Mielke, O., Liu, M., Counsell, C. E.
    Cochrane Database of Systematic Reviews, no. 2
    Contributions to Journals: Articles
  • Antiplatelet therapy for acute ischaemic stroke (updated Cochrane Review)

    Sandercock, P., Gubitz, G., Foley, P., Counsell, C. E.
    Cochrane Database of Systematic Reviews, no. 2
    Contributions to Journals: Articles
  • How to understand it:meta-analysis

    Counsell, C. E.
    Practical Neurology, vol. 3, no. 5, pp. 300-305
    Contributions to Journals: Editorials
  • Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischemic stroke (Cochrane review)

    Counsell, C. E., Sandercock, P.
    Stroke, vol. 33, no. 7, pp. 1925-1926
    Contributions to Journals: Review articles
  • Predicting outcome after acute and subacute stroke: development and validation of new prognostic models

    Counsell, C., Dennis, M., McDowall, M., Warlow, C.
    Stroke, vol. 33, no. 4, pp. 1041-1047
    Contributions to Journals: Articles
  • Anticoagulants for preventing recurrence following acute ischaemic stroke or transient ischaemic attack

    Mielke, O., Liu, M., Counsell, C. E., Sandercock, P.
    Cerebrovascular Diseases, vol. 13, no. Suppl 3
    Contributions to Journals: Articles
  • Assessment of facial expression production in Parkinson’s disease

    Benson, P. J., Counsell, C. E., McConachie, D. J. A., Liotti, M.
    Perception, vol. 31
    Contributions to Journals: Articles
  • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients

    Counsell, C. E., Antithrombotic Trialists' Collaboration
    British Medical Journal, vol. 324, pp. 71-86
    Contributions to Journals: Articles
  • Fibrinogen depleting agents for acute ischemic stroke

    Liu, M., Counsell, C. E., Zhao, X., Wardlaw, J.
    Cerebrovascular Diseases, vol. 13, no. Suppl 3
    Contributions to Journals: Abstracts
  • Improving the quality, number and progress of randomised control trials

    Prescott, R. J., Counsell, C. E., Gillespie, W. J., Grant, A. M., Russell, I. T., Ross, S.
    Clinical Trials. Duley, L., Farrell, B. (eds.). BMJ Publishing, pp. 57-71, 14 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters
  • Me and my neurological illness: Beware the tilted pelvis

    Counsell, C. E.
    Practical Neurology, vol. 2, pp. 232-233
    Contributions to Specialist Publications: Letters
  • Neuroprotection and Natural History in Parkinson Plus Syndromes (NNIPPS): design and progress of a clinical trial of the efficacy and safety of in Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA)

    Counsell, C. E., NNIPPS Study Group
    Movement Disorders, vol. 17, no. SUPPL 5
    Contributions to Journals: Articles
  • Prediction of outcome after stroke

    Counsell, C., Dennis, M., Lewis, S.
    The Lancet, vol. 358, no. 9292, pp. 1553
    Contributions to Journals: Letters
  • Systematic Review of Prognostic Models in Patients with Acute Stroke

    Counsell, C., Dennis, M.
    Cerebrovascular Diseases, vol. 12, no. 3, pp. 159-170
    Contributions to Journals: Articles
  • Reporting of randomised controlled trials

    Counsell, C. E.
    The Lancet, vol. 358, no. 9281, pp. 585
    Contributions to Journals: Letters
  • Factors that limit the number, progress and quality of randomised controlled trials: a systematic review

    Ross, S., Counsell, C. E., Gillespie, W. E., Grant, A. M., Prescott, R. J., Russell, I. T., Colthart, I. R., Kiauka, S., Russell, D., Shepherd, S. M.
    The Advanced Handbook of Methods in Evidence Based Healthcare. Stevens, A., Abrams, K., Brazier, J., Fitzpatrick, R., Lifford, R. (eds.). Sage Publications, pp. 38-55, 17 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters
  • Barriers to participation in randomised controlled trials: A systematic review

    Ross, S., Grant, A., Counsell, C., Gillespie, W., Russell, I., Prescott, R.
    Journal of Clinical Epidemiology, vol. 52, no. 12, pp. 1143-1156
    Contributions to Journals: Literature Reviews
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