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Health Services Research Unit

Professor Graeme MacLennan

Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

About
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge. 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • Systematic review of oncological outcomes following surgical management of localised renal cancer

    MacLennan, S., Imamura, M., Lapitan, M. C. M., Omar, M. I., Lam, T. B. L., Hilvano-Cabungcal, A., Royle, P., Stewart, F., MacLennan, G. S., MacLennan, S., Canfield, S., McClinton, S., Griffiths, T. R. L., Ljungberg, B., N'Dow, J. M. O.
    European Urology, vol. 61, no. 5, pp. 972-993
    Contributions to Journals: Articles

  • Long-term follow-up for mortality and cancer in a randomized placebo-controlled trial of vitamin D3 and/or calcium (RECORD trial)

    Avenell, A., Maclennan, G. S., Jenkinson, D. J., McPherson, G. C., McDonald, A. M., Pant, P. R., Grant, A. M., Campbell, M. K., Anderson, F. H., Cooper, C., Francis, R. M., Gillespie, W. J., Robinson, C. M., Torgerson, D. J., Wallace, W. A., RECORD Trial Group
    Journal of Clinical Endocrinology and Metabolism, vol. 97, no. 2, pp. 614-622
    Contributions to Journals: Articles

  • Rationing of total knee replacement: a cost-effectiveness analysis on a large trial data set

    Dakin, H., Gray, A., Fitzpatrick, R., Maclennan, G., Murray, D., KAT Trial Group
    BMJ Open, vol. 2, no. 1, e000332
    Contributions to Journals: Articles

  • Clustering in surgical trials: database of intracluster correlations

    Cook, J. A., Bruckner, T., MacLennan, G. S., Seiler, C. M.
    Trials, vol. 13, no. -, 2
    Contributions to Journals: Articles

  • Identifying active ingredients in complex behavioural interventions for obese adults with obesity-related co-morbidities or additional risk factors for co-morbidities: a systematic review

    Dombrowski, S. U., Sniehotta, F., Avenell, A., Johnston, M., MacLennan, G. S., Araujo-Soares, V.
    Health Psychology Review, vol. 6, no. 1, pp. 7-32
    Contributions to Journals: Articles

  • Process evaluation for the FEeding Support Team (FEST) randomised controlled feasibility trial of proactive and reactive telephone support for breastfeeding women living in disadvantaged areas

    Hoddinott, P., Craig, L., Maclennan, G., Boyers, D., Vale, L., On behalf of the NHS Grampian and the University of Aberdeen FEST project team
    BMJ Open, vol. 2, no. 2, e001039
    Contributions to Journals: Articles

  • The FEeding Support Team (FEST) randomised, controlled feasibility trial of proactive and reactive telephone support for breastfeeding women living in disadvantaged areas

    Hoddinott, P., Craig, L., Maclennan, G., Boyers, D., Vale, L., On behalf of the NHS Grampian and the University of Aberdeen FEST project team
    BMJ Open, vol. 2, no. 2, e000652
    Contributions to Journals: Articles

  • Surveillance mammography for detecting ipsilateral breast tumour recurrence and metachronous contralateral breast cancer: a systematic review

    Robertson, C., Ragupathy, S. K. A., Boachie, C., Fraser, C., Heys, S. D., Maclennan, G., Mowatt, G., Thomas, R. E., Gilbert, F. J., Mammographic Surveillance Health Technology Assessment Group
    European Radiology, vol. 21, no. 12, pp. 2484-2491
    Contributions to Journals: Articles

  • Assessing risk of bias in non-randomised studies and incorporating GRADE: Initial experience with a new Cochrane ‘risk of bias’ tool under development

    MacLennan, S., Imamura, M., Dahm, P., Nueberger, M., Reeves, B. C., MacLennan, G. S., Omar, M. I., McClinton, S., Griffiths, T. R. L., N'Dow, J. M. O.
    Contributions to Conferences: Papers

  • The hazards of extracting hazard ratios from survival curves for meta-analyses in observational studies

    Imamura, M., MacLennan, S., Dahm, P., Nueberger, M., Omar, M. I., MacLennan, G. S.
    Contributions to Conferences: Papers

  • Evidence for partial nephrectomy

    Lam, T. B. L., MacLennan, S., Imamura, M., Omar, M. I., MacLennan, G.
    Contributions to Conferences: Papers

  • Patellar resurfacing in total knee replacement: five-year clinical and economic results of a large randomized controlled trial

    Breeman, S., Campbell, M., Dakin, H., Fiddian, N., Fitzpatrick, R., Grant, A., Gray, A., Johnston, L., Maclennan, G., Morris, R., Murray, D., KAT Trial Group
    The Journal of Bone & Joint Surgery. American Volume, vol. 93, no. 16, pp. 1473-1481
    Contributions to Journals: Articles

  • The clinical effectiveness and cost-effectiveness of different surveillance mammography regimens after the treatment for primary breast cancer: systematic reviews registry database analyses and economic evaluation

    Robertson, C., Arcot Ragupathy, S. K., Boachie, C., Dixon, J. M., Fraser, C., Hernández, R., Heys, S., Jack, W., Kerr, G. R., Lawrence, G., MacLennan, G., Maxwell, A., McGregor, J., Mowatt, G., Pinder, S., Ternent, L., Thomas, R. E., Vale, L., Wilson, R., Zhu, S., Gilbert, F. J.
    Health Technology Assessment, vol. 15, no. 34, pp. v-vi, 1-322
    Contributions to Journals: Articles

  • Further use for the harvest plot: a novel method for quantitative and qualitative data synthesis

    Crowther, M., Avenell, A., MacLennan, G. S., Mowatt, G.
    Research Synthesis Methods, vol. 2, no. 2, pp. 79-83
    Contributions to Journals: Articles

  • Applying psychological theories to evidence-based clinical practice: identifying factors predictive of lumbar spine x-ray for low back pain in UK primary care practice

    Grimshaw, J. M., Eccles, M. P., Steen, N., Johnston, M., Pitts, N. B., Glidewell, E., Maclennan, G., Thomas, R. E., Bonetti, D. L., Walker, A. E.
    Implementation Science, vol. 6, pp. 55
    Contributions to Journals: Articles

  • Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections: a randomised controlled trial to compare paper-based and web-based modelling experiments

    Treweek, S. P., Ricketts, I. W., Francis, J., Eccles, M., Bonetti, D., Pitts, N. B., Maclennan, G., Sullivan, F., Jones, C., Weal, M., Barnett, K.
    Implementation Science, vol. 6, no. 1, pp. 16
    Contributions to Journals: Articles

  • Systematic review of the clinical effectiveness of surgical management for localised renal cell carcinoma

    Imamura, M., MacLennan, S., Lapitan, M. C. M., Omar, M. I., Lam, T., Hilvano-Cabungcal, A. M., Royle, P. L., Stewart, F., MacLennan, G., MacLennan, S., Canfield, S. E., McClinton, S., Griffiths, T. R. L., Ljungberg, B., N'Dow, J., UCAN Systematic Review Reference Group, EAU Guideline Group for renal cell carcinoma
    Commissioned by European Association of Urology. University of Aberdeen: Academic Urology Unit
    Books and Reports: Commissioned Reports

  • Calcium and heart attacks: Authors' reply

    Bolland, M. J., Avenell, A., Baron, J. A., Grey, A., Reid, I. R., MacLennan, G. S., Gamble, G. D.
    BMJ (Online), vol. 341, no. 7773, pp. 569
    Contributions to Journals: Letters

  • Clinicians' caseload management behaviours as explanatory factors in patients' length of time on caseloads: a predictive multilevel study in paediatric community occupational therapy

    Kolehmainen, N., MacLennan, G., Francis, J. J., Duncan, E. A. S.
    BMC Health Services Research, vol. 10, no. 249, 249
    Contributions to Journals: Articles

  • Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis

    Bolland, M. J., Avenell, A., Baron, J. A., Grey, A., MacLennan, G. S., Gamble, G. D., Reid, I. R.
    British Medical Journal, vol. 341, no. -, c3691
    Contributions to Journals: Articles

  • Study of progesterone for the prevention of preterm birth in twins (STOPPIT): findings from a trial-based cost-effectiveness analysis

    Eddama, O., Petrou, S., Regier, D., Norrie, J., MacLennan, G., MacKenzie, F., Norman, J. E.
    International Journal of Technology Assessment in Health Care, vol. 26, no. 2, pp. 141-148
    Contributions to Journals: Articles

  • Applying psychological theories to evidence-based clinical practice: identifying factors predictive of placing preventive fissure sealants

    Bonetti, D., Johnston, M., Clarkson, J. E., Grimshaw, J., Pitts, N. B., Eccles, M., Steen, N., Thomas, R., Maclennan, G., Glidewell, E., Walker, A. E.
    Implementation Science, vol. 5, pp. 25
    Contributions to Journals: Articles

  • The clinical effectiveness of transurethral incision of the prostate: a systematic review of randomised controlled trials

    Lourenco, T., Shaw, M., Fraser, C. M., MacLennan, G. S., N'Dow, J. M. O., Pickard, R.
    World Journal of Urology, vol. 28, no. 1, pp. 23-32
    Contributions to Journals: Articles

  • Quality of life in the five years after intensive care: a cohort study

    Cuthbertson, B., Roughton, S., Jenkinson, D. J., MacLennan, G. S., Vale, L. D.
    Critical Care, vol. 14, no. 1, R6
    Contributions to Journals: Articles

  • Factors Influencing the Participation of Older People in Clinical Trials: Data Analysis from the MAVIS Trial

    Fearn, P., Avenell, A., McCann, S. K., Milne, A. C., MacLennan, G. S., MAVIS Trial Group
    Journal of Nutrition, Health & Aging, vol. 14, no. 1, pp. 51-56
    Contributions to Journals: Articles
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