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Aberdeen Centre for Evaluation

Professor Miriam Brazzelli

Professor Miriam Brazzelli
Professor Miriam Brazzelli
Professor Miriam Brazzelli

Personal Chair

About
Email Address
m.brazzelli@abdn.ac.uk
Telephone Number
+44 (0)1224 438404
Office Address

Health Services Research Unit
University of Aberdeen
3rd Floor, Health Sciences Building
Foresterhill
Aberdeen, AB25 2ZD

 

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Miriam Brazzelli obtained a Phisiotherapy degree from San Carlo Borromeo Physiotherapy School in 1988 and an honours degree in Psychology (Cognitive Psychology) from the University of Turin (Italy) in 1997. Following early career appointments within the health service in the fields of physiotherapy and neuropsychology she joined the Unit in Jan 1999. She was subsequently awarded a Research Fellowship by the Scottish Executive Health Department, Chief Scientist Office in 2005 to study the methodology of systematic reviews of diagnostic test accuracy studies. She obtained a PhD (Public Health Sciences) from the University of Edinburgh in 2011. She re-joined the Unit in 2012 (Feb) as lead of the Evidence Synthesis Team withint the Health Care Assessment Programme. The focus of her research is on complex evidence syntheses and health technology assessments, which aim to assess the clinical- and cost-effectiveness of new and established healthcare interventions.  

Qualifications:

Physiotherapy Degree, Physiotherapy School, Azienda Ospedaliera San Carlo Borromeo, Milan, Italy (1988)

BSc, Hons Psychology, University of Turin, Italy (1997)

PhD by Research (Public Health Sciences), University of Edinburgh (2011)

Publications

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  • Economic evaluation of surgical treatments for women with stress urinary incontinence: a cost-utility and value of information analysis

    Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S., Ternent, L., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Becker, F., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L., Craig, D.
    BMJ Open, vol. 10, no. 6, 035555
    Contributions to Journals: Articles

  • Enzalutamide with ADT for treating metastatic hormone-sensitive prostate cancer

    Kopasker, D., Robertson, C., Aucott, L., Vadiveloo, T., Imamura, M., Manson, P., Walker, A., Urquhart, G., Brazzelli, M., Scotland, G., Aberdeen HTA Group
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Fostamatinib for treating chronic immune thrombocytopenia

    Jacobsen, E., Boyers, D., Scott, N., Cruickshank, M., Imamura, M., Manson, P., Preston, G., Brazzelli, M.
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Can surgery be avoided in patients with symptomatic gallstone disease and no complications?

    Brazzelli, M., Avenell, A., Gillies, K., Ramsay, C., Ahmed, I.
    The BMJ, vol. 367, no. 8218, l5709
    Contributions to Journals: Comments and Debates

  • Surgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials

    Imamura, M., Hudson, J., Wallace, S. A., MacLennan, G., Shimonovich, M., Omar, M. I., Javanbakht, M., Moloney, E., Becker, F., Ternent, L., Montgomery, I., Mackie, P., Saraswat, L., Monga, A., Vale, L., Craig, D., Brazzelli, M.
    BMJ, vol. 365, l1842
    Contributions to Journals: Articles

  • Interventions for treating people with symptoms of bladder pain syndrome: A network meta-analysis

    Imamura, M., Scott, N. W., Ogah, J. A., Ford, A. A., Wallace, S. A., Dubos, Y. A., Brazzelli, M.
    Cochrane Database of Systematic Reviews, vol. 2019, no. 5, CD013325.
    Contributions to Journals: Articles

  • Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation

    Brazzelli, M., Javanbakht, M., Imamura, M., Hudson, J., Moloney, E., Becker, F., Wallace, S., Omar, M. I., Shimonovich, M., MacLennan, G., Ternent, L., Vale, L., Montgomery, I., Mackie, P., Saraswat, L., Monga, A., Craig, D.
    Health Technology Assessment, vol. 23, no. 14, pp. 1-306
    Contributions to Journals: Articles

  • Lanadelumab for preventing recurrent attacks of hereditary angioedema.

    Robertson, C., Walker, A., Jacobsen, E., Aucott, L., Herriot, R., Scotland, G., Brazzelli, M.
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Lorlatinib for previously treated ALK-positive advanced non-small-cell lung cancer

    Robertson, C., Fielding, S., Walker, A., Kopasker, D., Vadiveloo, T., Manson, P., Price, G., Brazzelli, M., Scotland, G.
    Commissioned by National Institute for Health and Care Excellence. Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports

  • Risankizumab for treating moderate to severe plaque psoriasis

    Imamura, M., Cooper, D., Hernández, R. A., Ormerod, A., Scotland, G., Brazzelli, M., Aberdeen HTA Group
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • TYRX Absorbable Antibacterial Envelope for preventing infection from cardiac implantable electronic devices.

    Hernández, R. A., Robertson, C., Scott, N., Scotland, G., Booth, C., Manson, P., Broadhurst, P., Brazzelli, M.
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • The ARCHITECT and Alinity urine NGAL assays, urine NephroCheck test, and urine and plasma NGAL tests to help assess the risk of acute kidney injury in people who are being considered for admission to critical care

    Brazzelli, M., Aucott, L., Aceves Martins, M., Robertson, C., Jacobsen, E., Imamura, M., Poobalan, A., Manson, P., Scotland, G., Kaye, C., Sawhney, S., Boyers, D.
    National Institute for Health and Care Excellence (NICE). 376 pages
    Books and Reports: Commissioned Reports

  • Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation

    Brazzelli, M., Hernández, R., Sharma, P., Robertson, C., Shimonovich, M., MacLennan, G., Fraser, C., Jamieson, R., Vallabhaneni, S. R.
    Health Technology Assessment, vol. 22, no. 72, pp. 1-220
    Contributions to Journals: Articles

  • Child food insecurity in the UK: a rapid review

    Aceves Martins, M., Cruickshank, M., Fraser, C., Brazzelli, M. G.
    Public Health Research, vol. 6, no. 13
    Contributions to Journals: Articles

  • COMPARISON OF NINE SURGICAL TREATMENTS FOR WOMEN WITH STRESS URINARY INCONTINENCE: A COST-EFFECTIVENESS AND VALUE OF INFORMATION ANALYSIS

    Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S. A., Ternent, L., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L., Craig, D.
    11th Annual European UroGynaecological Association Congress
    Contributions to Conferences: Abstracts

  • Dupilumab for treating adults with moderate to severe atopic dermatitis.

    Hernández, R. A., Cruickshank, M., Dimitrova, M. P., Cooper, D. J., Aucott, L. S., Fraser, C., Shimonovich, M., Ormerod, A., Scotland, G. S., Brazzelli, M. G.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports

  • EMA and NICE Appraisal Processes for Cancer Drugs: Current Status and Uncertainties

    Dickson, R., Boland, A., Duarte, R., Kotas, E., Woolacott, N., Hodgson, R., Riemsma, R., Grimm, S., Ramaekers, B., Joore, M., Büyükkaramikli, N., Kaltenthaler, E., Stevenson, M., Pandor, A., Edwards, S., Hoyle, M., Shepherd, J., Armoiry, X., Brazzelli, M.
    Applied Health Economics and Health Policy, vol. 16, no. 4, pp. 429-432
    Contributions to Journals: Articles

  • Multiple-frequency bioimpedance devices for fluid management in people with chronic kidney disease receiving dialysis: a systematic review and economic evaluation

    Scotland, G., Cruickshank, M., Jacobsen, E., Cooper, D., Fraser, C., Shimonovich, M., Marks, A., Brazzelli, M.
    Health Technology Assessment, vol. 22, no. 1, pp. 1-138
    Contributions to Journals: Literature Reviews

  • Abiraterone for treating newly diagnosed metastatic hormone-naïve prostate cancer.

    Cummins, E., Aucott, L. S., Robertson, C., Fraser, C., Johnston, R., Lam, T., Brazzelli, M. G.
    Commissioned by National Institute for Health and Care Excellence. Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports

  • Teduglutide for treating short bowel syndrome

    Scotland, G., Kopasker, D., Scott, N., Cruickshank, M., Hernández, R. A., Fraser, C. M., McLean, M., McKinlay, A., Brazzelli, M.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 142 pages
    Books and Reports: Commissioned Reports

  • Doppler ultrasound, CT angiography, MR angiography, and contrast-enhanced MR angiography versus intra-arterial angiography for moderate and severe carotid stenosis in symptomatic patients

    Chappell, F. M., Wardlaw, J. M., Brazzelli, M., Best, J. J.
    Cochrane Database of Systematic Reviews, vol. 2017, no. 2, CD007423
    Contributions to Journals: Articles

  • Aflibercept for treating myopic choroidal neovascularisation

    Brazzelli, M. G., Cummins, E., Fielding, S. A., Cruickshank, M., Fraser, C. M., Azuara-Blanco, A.
    Commissioned by Department of Health via the NIHR HTA Programme. NICE Fast Track Appraisal Programme. London: National Institute for Health and Care Excellence. 252 pages
    Books and Reports: Commissioned Reports

  • The eEffectiveness and cost-effectiveness of Surgical Treatments for womEn with stRess urinary incontinence:: an evidence synthesis (ESTER)

    Brazzelli, M., Craig, D., Imamura, M., Wallace, S., MacLennan, G., Hudson, J., Saraswat, L., Omar, M. I., Montgomery, I.
    Contributions to Journals: Registered Reports

  • Physical Fitness Training for Patients with Stroke

    Saunders, D. H., Sanderson, M., Hayes, S., Kilrane, M., Greig, C. A., Brazzelli, M., Mead, G. E.
    Stroke, vol. 47, no. 9, pp. e219-e220
    Contributions to Journals: Articles

  • A randomised controlled trial comparing laparoscopic cholecystectomy with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones. (C-Gall trial)

    Malik, M., Murchie, P., Gillies, K., Brazzelli, M. G., Avenell, A., Hernandez, R., Norrie, J., Blazeby, J., Ramsay, C., Ahmed, I.
    International Surgical Congress of the Association-of-Surgeons-of-Great-Britain-and-Ireland, pp. 195-196
    Contributions to Journals: Abstracts

  • Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

    Cruickshank, M., Henderson, L., MacLennan, G., Fraser, C., Campbell, M., Blackwood, B., Gordon, A., Brazzelli, M.
    Health Technology Assessment, vol. 20, no. 25, pp. 0-120
    Contributions to Journals: Literature Reviews

  • Author Response - ABCD2 score and secondary stroke prevention: Meta-analysis and effect per 1,000 patients triaged

    Wardlaw, J. M., Brazzelli, M., Chappell, F., Dennis, M. S., Sandercock, P. A.
    Neurology, vol. 86, no. 7, pp. 697
    Contributions to Journals: Letters

  • Physical fitness training for stroke patients

    Sanders, D. H., Sanderson, M., Hayes, S., Kilrane, M., Greig, C. A., Brazzelli, M., Mead, G. E.
    Cochrane Database of Systematic Reviews, no. 3, pp. 1-411
    Contributions to Journals: Literature Reviews

  • The clinical and cost-effectiveness of open mesh repairs in adults presenting with a clinically diagnosed unilateral, primary inguinal hernia who are operated in an elective setting: systematic review and economic evaluation

    Sharma, P., Boyers, D., Scott, N. W., Hernandez, R. A., Fraser, C. M., Cruickshank, M., Ahmed, I., Ramsay, C. R., Brazzelli, M. G.
    Health Technology Assessment, vol. 19, no. 92, pp. i - 141
    Contributions to Journals: Literature Reviews

  • Collagenase clostridium histolyticum for the treatment of Dupuytren’s contracture: systematic review and economic evaluation

    Brazzelli, M., Cruickshank, M., Tassie, E., McNamee, P., Robertson, C., Elders, A., Fraser, C., Hernandez, R., Lawrie, D., Ramsay, C.
    Health Technology Assessment, vol. 19, no. 90, pp. 1-202
    Contributions to Journals: Articles

  • ABCD2 score and secondary stroke prevention: Meta-analysis and effect per 1,000 patients triaged

    Wardlaw, J. M., Brazzelli, M., Chappell, F. M., Miranda, H., Shuler, K., Sandercock, P. A. G., Dennis, M. S.
    Neurology, vol. 85, no. 4, pp. 373-380
    Contributions to Journals: Articles

  • Ablative therapy for people with localised prostate cancer: a systematic review and economic evaluation

    Ramsay, C. R., Adewuyi, T. E., Gray, J., Hislop, J., Shirley, M. D., Jayakody, S., MacLennan, G., Fraser, C., MacLennan, S., Brazzelli, M., N'Dow, J., Pickard, R., Robertson, C., Rothnie, K., Rushton, S. P., Vale, L., Lam, T. B.
    Health Technology Assessment, vol. 19, no. 49, pp. 1-524
    Contributions to Journals: Articles

  • Is self-monitoring an effective option for people receiving long-term vitamin K antagonist therapy? A systematic review and economic evaluation

    Sharma, P., Scotland, G., Cruickshank, M., Tassie, E., Fraser, C., Burton, C. D., Croal, B., Ramsay, C. R., Brazzelli, M. G.
    BMJ Open, vol. 5, no. 6, e007758
    Contributions to Journals: Articles

  • Assessment of diagnostic tests and the impact on decision making: self-monitoring of oral anticoagulation therapy: Oral presentation

    Sharma, P., Scotland, G. S., Cruickshank, M., Tassie, E., Fraser, C. M., Burton, C. D., Croal, B. L., Ramsay, C. R., Brazzelli, M. G.
    Contributions to Conferences: Other Contributions

  • The clinical effectiveness and cost-effectiveness of point-of-care tests (CoaguChek system, INRatio2 PT/INR monitor and ProTime Microcoagulation system) for the self-monitoring of the coagulation status of people receiving long-term vitamin K antagonist therapy, compared with standard UK practice: systematic review and economic evaluation

    Sharma, P., Scotland, G. S., Cruickshank, M., Tassie, E., Fraser, C., Burton, C. D., Croal, B., Ramsay, C. R., Brazzelli, M.
    Health Technology Assessment, vol. 19, no. 48, pp. 1-172
    Contributions to Journals: Articles

  • Systematic review of the clinical and cost effectiveness of cholecystectomy versus observation/conservative management for uncomplicated symptomatic gallstones or cholecystitis

    Brazzelli, M., Cruickshank, M., Kilonzo, M., Ahmed, I., Stewart, F., McNamee, P., Elders, A., Fraser, C., Avenell, A., Ramsay, C.
    Surgical Endoscopy, vol. 29, no. 3, pp. 637-647
    Contributions to Journals: Articles

  • Optic nerve head and fibre layer imaging for diagnosing glaucoma

    Michelessi, M., Lucenteforte, E., Oddone, F., Brazzelli, M. G., Parravano, M., Franchi, S., Ng, S. M., Virgili, G.
    Cochrane Database of Systematic Reviews, no. 11, CD008803
    Contributions to Journals: Literature Reviews

  • Clinical effectiveness and cost-effectiveness of cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults presenting with uncomplicated symptomatic gallstones or cholecystitis: a systematic review and economic evaluation

    Brazzelli, M., Cruickshank, M., Kilonzo, M., Ahmed, I., Stewart, F., McNamee, P., Elders, A., Fraser, C., Avenell, A., Ramsay, C.
    Health Technology Assessment, vol. 18, no. 55, pp. 1-102
    Contributions to Journals: Articles

  • An assessment of the cost-effectiveness of magnetic resonance, including diffusion-weighted imaging in patients with transient ischaemic attack and minor stroke: a systematic review, meta-analysis and economic evaluation

    Wardlaw, J., Brazzelli, M., Miranda, H., Chappell, F., McNamee, P., Scotland, G. S., Quayyum, Z., Martin, D., Shuler, K., Sandercock, P., Dennis, M.
    Health Technology Assessment, vol. 18, no. 27, pp. 1-368, v-xxvi
    Contributions to Journals: Articles

  • Physical Fitness Training for Patients With Stroke: An Updated Review

    Saunders, D. H., Sanderson, M., Brazzelli, M., Greig, C. A., Mead, G. E.
    Stroke, vol. 45, no. 4, pp. e54-e55
    Contributions to Journals: Literature Reviews

  • Diffusion-weighted imaging and diagnosis of transient ischemic attack

    Brazzelli, M., Chappell, F. M., Miranda, H., Shuler, K., Dennis, M., Sandercock, P. A. G., Muir, K., Wardlaw, J. M.
    Annals of Neurology, vol. 75, no. 1, pp. 67-76
    Contributions to Journals: Articles

  • Transcranial Doppler sonography for detecting stenosis or occlusion of intracranial arteries in people with acute ischaemic stroke

    Mattioni, A., Brazzelli, M., Cenciarelli, S., Mazzoli, T., Del Sette, M., Gandolfo, C., Marinoni, M., Finocchi, C., Saia, V., Eusebi, P., Sandercock, P. A. G., Ricci, S.
    Cochrane Database of Systematic Reviews, no. 9, pp. 1-15
    Contributions to Journals: Literature Reviews

  • Clinical and imaging services for TIA and minor stroke: results of two surveys of practice across the UK

    Brazzelli, M., Shuler, K., Quayyum, Z., Hadley, D., Muir, K., McNamee, P., De Wilde, J., Dennis, M., Sandercock, P., Wardlaw, J. M.
    BMJ Open, vol. 3, no. 8, 3359
    Contributions to Journals: Articles

  • Physical fitness training for stroke patients

    Saunders, D. H., Sanderson, M., Brazzelli, M., Greig, C. A., Mead, G. E.
    Cochrane Database of Systematic Reviews, no. 10, CD003316
    Contributions to Journals: Literature Reviews

  • Physical fitness training for patients with stroke: updated review

    Brazzelli, M. G., Saunders, D. H., Greig, C. A., Mead, G. E.
    Stroke, vol. 43, no. 4, pp. e39-e40
    Contributions to Journals: Articles

  • Behavioural and cognitive interventions with or without other treatments for the management of faecal incontinence in children

    Brazzelli, M. G., Griffiths, P. V., Cody, J. D., Tappin, D.
    Cochrane Database of Systematic Reviews, no. 12, CD002240
    Contributions to Journals: Articles

  • Physical fitness training for stroke patients

    Brazzelli, M., Saunders, D. H., Greig, C. A., Mead, G. E.
    Cochrane Database of Systematic Reviews, no. 11, CD003316
    Contributions to Journals: Literature Reviews

  • Evidence-based guideline: the role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: report of the Therapeutics and Technology Subcommittee of the American Academy of Neurology

    Brazzelli, M. G., Sandercock, P., Wardlaw, J.
    Neurology, vol. 76, no. 23, pp. 2036-2038
    Contributions to Journals: Letters

  • MRI versus CT for detection of acute vascular lesions in patients presenting with stroke symptoms

    Brazzelli, M., Sandercock, P. A., Celani, M. G., Righetti, E., Chappell, F. M., Arestis, N., Wardlaw, J. M., Deeks, J. J.
    Contributions to Journals: Short Survey

  • A systematic review of clinical trials of pharmacological interventions for acute ischaemic stroke (1955-2008) that were completed, but not published in full

    Gibson, L. M., Brazzelli, M. G., Thomas, B. M., Sandercock, P. A. G.
    Trials, vol. 11, 43
    Contributions to Journals: Articles
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