BSc (Hons), MLitt, PhD
Senior Trial Manager
- About
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- Email Address
- s.c.cotton@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438178
- Office Address
Health Services Research Unit Health Sciences Building (Third Floor) Foresterhill Aberdeen AB25 2ZD
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I joined HSRU in 2007 as a trial manager. I graduated from the University of Aberdeen with a BSc in Health Sciences in 1993, an MLitt in 1995, and a PhD in 2007. Prior to joining the Unit, I worked in the Department of Public Health at the University of Aberdeen.
I am the Senior Trial Manager within CHaRT supporting the portfolio of trials. I also currently work on the BICS trial - a multicentre trial investigating the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease.
Previously I was the Deputy Senior Trial Manager and supported a number of studies including RAACENO, EMPOWER and ELECTRIC (all now completed). I also worked as trial manager on a number of CHaRT trials, including TWICS, CLASS, NIAMI, FOCCUS, REFLUX and the Cysteamine in CF study.
I am interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.
Qualifications
- BSc Health Sciences1993 - University of Aberdeen
- MLitt by research1994 - University of Aberdeen
- PhD Public Health2008 - University of Aberdeen
- Research
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Research Overview
Trial methodology & trial management
Research Areas
Applied Health Sciences
Nutrition and Health
Current Research
I am the Senior Trial Manager within CHaRT supporting the portfolio of trials. I also currently work on the BICS trial - a multicentre trial investigating the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease.
I am interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.
Past Research
Since joining the Unit I have worked on a number of trials that have now been completed.
TWICS - a multicentre trial investigating the effectiveness of low dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease.
CLASS - a multicentre trial comparing foam sclerotherapy and endovenous laser ablation with conventional surgery in patients with varicose veins;
NIAMI - a phase II multicentre trial investigating whether an intravenous injection of sodium nitrite given immediately before the infarct related artery is opened reduces ischaemia reperfusion injury in patients with myocardial infarction;
FOCCUS - a pragmatic multi-centred randomised controlled trial of surgical HDU care versus HDU care delivered in an ICU and pre-operative fluid loading in high-risk patients undergoing major elective surgery
REFLUX - a multi-centre randomised trial comparing a policy of relatively early laparoscopic surgery with a continued best medical management policy for people with more severe gastro-oesophageal reflux disease.
The Cysteamine in CF study - a single-centre, single group open label study of oral cysteamine in patients with Cystic Fibrosis.
I also supported RAACENO, EMPOWER and ELECTRIC (all now completed) as senior trial manager.
- Teaching
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Teaching Responsibilities
I have supervised a number of undergraduate and Masters level research projects, including topics such as provision of information to potential participants, strategies to increase response rates, and outcome measures.
Non-course Teaching Responsibilities
Outwith the University, I am a faculty member on the Edinburgh Clinical Trial Management Course (ECTMC).
- Publications
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Text Messages With Financial Incentives for Men With Obesity: A Randomized Clinical Trial
JAMA, vol. 332, no. 1, pp. 31-40Contributions to Journals: ArticlesLaparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT
Health Technology Assessment, vol. 28, no. 26, pp. 1-151Contributions to Journals: ArticlesDirect and indirect costs of paediatric asthma in the UK: a cost analysis
Archives of Disease in ChildhoodContributions to Journals: ArticlesBisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial
JAMAContributions to Journals: ArticlesExploring Opinions and Concerns about the Human Papillomavirus Vaccine on a United Kingdom Online Discussion Forum
Journal of Colposcopy and Lower Genital Tract Pathology, vol. 1, no. 3, pp. 117-123Contributions to Journals: ArticlesThe Bisoprolol in COPD Study (BICS): A UK Randomized Controlled Trial of Bisoprolol in People With COPD at Risk of Exacerbation
American Journal of Respiratory and Critical Care Medicine, vol. 2024, no. 209Contributions to Journals: AbstractsEffectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial
BMJ, vol. 383, e075383Contributions to Journals: ArticlesEmergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients With Exsanguinating Hemorrhage: The UK-REBOA Randomized Clinical Trial
JAMA, vol. 330, no. 19, pp. 1862-1871Contributions to Journals: ArticlesEmergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients with Exsanguinating Hemorrhage: The UK-REBOA Randomized Clinical Trial
JAMA, vol. 330, no. 19, pp. 1862-1871Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1001/jama.2023.20850
- [ONLINE] View publication in Scopus
A qualitative process evaluation within a clinical trial that used healthcare technologies for children with asthma: insights and implications
PloS ONE, vol. 18, no. 1, 0280086Contributions to Journals: Articles