Professor Graeme MacLennan

Director (CHaRT)

Email Address: g.maclennan@abdn.ac.uk
Telephone Number: +44 (0)1224 438147
Office Address: Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD
School/Department: School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT.

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.

Qualifications

BSc Mathematics
1997 - University of Aberdeen
MSc Applied Statistics
2004 - Sheffield Hallam University

Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester).

Research on making trials more efficient, collaborating with Trial Forge.

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

Update

Biography

Qualifications

Research Overview

Current Research

Teaching Responsibilities

Treatment of Advanced Glaucoma Study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma—study protocol

A Systematic Review of Health Economic Evaluations of Surgical Treatments for Women with Stress Urinary Incontinence

TISU: Extracorporeal shockwave lithotripsy, as first treatment option, compared with direct progression to ureteroscopic treatment, for ureteric stones: study protocol for a randomised controlled trial

Cancer and vitamin D supplementation: a systematic review and meta-analysis

Instrumental variable methods for a binary outcome were used to informatively address non-compliance in a randomised trial in surgery

The split-plot design was useful for evaluating complex, multi-level interventions but there is need for improvement in its design and report

Systematic Techniques to Enhance rEtention in Randomised controlled trials: the STEER study protocol

How to resolve discrepancies when findings from randomized controlled trials and meta-analyses disagree?

Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): Study protocol for a randomised controlled trial

Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease and cancer: a systematic review and meta-analysis

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Books and Reports

Chapters in Books, Reports and Conference Proceedings

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Contributions to Journals