Professor Alison Avenell

Clinical Chair in Health Services Research

Email Address: a.avenell@abdn.ac.uk
Telephone Number: +44 (0)1224 438164
Office Address: Health Services Research Unit
3rd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD
School/Department: School of Medicine, Medical Sciences and Nutrition

Biography

Alison Avenell joined the Unit in 1998, as a Clinical Research Fellow. She was subsequently funded by the Chief Scientist Office (CSO) of the Scottish Government Health Directorates as a Clinical Research Fellow to undertake research in the MRC funded RECORD trial, which examined the effect of calcium and/or vitamin D supplementation in the secondary prevention of osteoporotic fractures. She also led the MAVIS trial which examined the effectiveness of vitamin and mineral supplementation in preventing infections in older people, and helped lead the SIGNET trial of glutamine and selenium supplementation in critical illness. She was a CSO funded Career Scientist and currently has a clinical chair in health services research and is an Honorary Consultant in Clinical Biochemistry, undertaking systematic reviews and randomised controlled trials of treatments for adult obesity, and under-nutrition in clinical practice.

Research

Current Research

Current projects

Completed projects

RECORD
ROMEO

Publications

Page 1 of 9 Results 1 to 25 of 224

Investigating Health Professionals’ Perspectives and Experiences of Food Security-Related Conversations in Diabetes Care
2024 - E-pub ahead of print
Mohamed, S., Avenell, A., Keen, A., Douglas, F.
Diabetic Medicine
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1111/dme.15470
Laparoscopic cholecystectomy versus conservative management for uncomplicated symptomatic gallstones: economic evaluation based on the C-GALL trial
2024 - Accepted/In press
Hernández, R. A., Ahmed, I., Edwards, K., Hudson, J., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B. L., MacLennan, G., Murchie, P., Ramsay, C.
British Journal of Surgery
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1093/bjs/znae293
A survey of experts to identify methods to detect problematic studies: Stage 1 of the INSPECT-SR Project
2024 - Published
Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Avenell, A., Barbour, V., Bordewijk, E., Brown, N. J. L., Clarke, M., Dumville, J. C., Grohmann, S., Gurrin, L. C., Hayden, J. A., Hunter, K. E., Lam, E., Lasserson, T., Li, T., Lensen, S. F., Liu, J., Lundh, A., Meyerowitz-Katz, G., Mol, B. W., O’Connell, N. E., Parker, L., Redman, B., Seidler, A. L., Sheldrick, K. A., Sydenham, E., Dahly, D. L., van Wely, M., Bero, L., Kirkham, J.
Journal of Clinical Epidemiology, vol. 175, 111512
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.jclinepi.2024.111512
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/24326/1/Wilkinson_etal_JCE_A_Survey_experts_VOR.pdf
- [ONLINE] View publication in Scopus
Barriers to investigating and reporting research misconduct: prioritising publication integrity
2024 - Published
Avenell, A., Klein, A. A., Byrne, J. A., Wilmshurst, P., Bolland, M. J., Grey, A.
BMJ (Clinical research ed.), vol. 386, q2018
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmj.q2018
- [ONLINE] View publication in Scopus
Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: findings from the LACE sarcopenia trial
2024 - Published
Shrestha, A., Bashir, T., Achison, M., Adamson, S., Akpan, A., Aspray, T. J., Avenell, A., Band, M. M., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Hume, C. L., Jackson, T. A., Kerr, S., Kilgour, A. H. M., Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Sayer, A. A., Rossios, C., Smith, K. T., Soiza, R., Steves, C. J., Struthers, A. D., Tiwar, D., Whitney, J., Witham, M. D., Kemp, P. R.
PloS ONE, vol. 19, no. 8, e0307268
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0307268
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23988/1/Shrestha_etal_PO_Association_Of_Bradykinin_VoR.pdf
How to improve assessments of publication integrity
2024 - Published
Grey, A., Avenell, A., Klein, A. A., Byrne, J. A., Wilmshurst, P., Bolland, M. J.
Nature, vol. 632, no. 8023, pp. 26-28
Contributions to Journals: Comments and Debates
- [ONLINE] DOI: https://doi.org/10.1038/d41586-024-02449-8
Text Messages With Financial Incentives for Men With Obesity: A Randomized Clinical Trial
2024 - Published
Hoddinott, P., O'Dolan, C., Macaulay, L., Dombrowski, S. U., Swingler, J., Cotton, S., Avenell, A., Getaneh, A. M., Gray, C., Hunt, K., Kee, F., MacLean, A., McKinley, M., Torrens, C., Turner, K., van der Pol, M., MacLennan, G.
JAMA, vol. 332, no. 1, pp. 31-40
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1001/jama.2024.7064
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23471/1/Hoddinott_etal_JAMA_Text_Messages_With_AAM.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] https://abdn.elsevierpure.com/en/publications/c9e67f77-0c1d-4f85-a5f9-d0bcf52e5646
Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT
2024 - Published
Innes, K., Ahmed, I., Hudson, J., Hernández, R. A., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
Health Technology Assessment, vol. 28, no. 26, pp. 1-151
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3310/MNBY3104
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23735/1/Innes_etal_HTA_Laparoscopic_Cholecystectomy_Versus_VoR.pdf
Statistical Techniques to Assess Publication Integrity in Groups of Randomised Trials: A Narrative Review
2024 - Published
Bolland, M. J., Avenell, A., Grey, A.
Journal of Clinical Epidemiology, vol. 170, 111365
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.jclinepi.2024.111365
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23615/1/Bolland_etal_JCE_Statistical_techniques_assess_VOR.pdf
Guidance on terminology, application, and reporting of citation searching: the TARCiS statement
2024 - Published
Hirt, J., Nordhausen, T., Fuerst, T., Ewald, H., Appenzeller-Herzog, C., TARCiS study group, Avenell, A.
BMJ, vol. 385, e078384
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmj-2023-078384
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23507/1/Hirt_etal_BMJ_Guidances_On_Terminology_AAM.pdf
A survey of experts to identify methods to detect problematic studies: Stage 1 of the INSPECT-SR Project
2024 - Published
Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Avenell, A., Barbour, V., Bordewijk, E. M., Brown, N. J. L., Clarke, M., Dumville, J., Grohmann, S., Gurrin, L. C., Hayden, J. A., Hunter, K. E., Lam, E., Lasserson, T., Li, T., Lensen, S., Liu, J., Lundh, A., Meyerowitz-Katz, G., Mol, B. W., O'Connell, N. E., Parker, L., Redman, B., Seidler, A. L., Sheldrick, K., Sydenham, E., Dahly, D. L., van Wely, M., Bero, L., Kirkham, J. J.
Working Papers: Preprint Papers
- [ONLINE] DOI: https://doi.org/10.1101/2024.03.18.24304479
Publication integrity: what is it, why does it matter, how it is safeguarded and how could we do better?
2024 - E-pub ahead of print
Bolland, M. J., Avenell, A., Grey, A.
Journal of the Royal Society of New Zealand
Contributions to Journals: Review articles
- [ONLINE] DOI: https://doi.org/10.1080/03036758.2024.2325004
- [ONLINE] View publication in Scopus
Letter to the editor concerning "characteristics of baseline frequency data in spinal RCTs do not suggest widespread non-random allocation" by MMS Levayer, et al. (Eur Spine J; 2023; 32: 3009-3014)
2024 - Published
Bolland, M. J., Avenell, A., Grey, A.
European Spine Journal, vol. 33, no. 4, pp. 1703-1704
Contributions to Journals: Letters
- [ONLINE] DOI: https://doi.org/10.1007/s00586-024-08167-z
- [ONLINE] View publication in Scopus
- [ONLINE] https://abdn.elsevierpure.com/en/publications/b5be6f73-43a3-469a-a329-3c2e873b14c0
Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions
2024 - Accepted/In press
Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Alfirevic, Z., Avenell, A., Barbour, V., Brown, N. J. L., Carlisle, J., Clarke, M., Dicker, P., Dumville, J., Grey, A., Grohmann, S., Gurrin, L. C., Hayden, J. A., Heathers, J., Hunter, K. E., Lasserson, T., Lam, E., Lensen, S., Li, T., Li, W., Loder, E., Lundh, A., Meyerowitz-Katz, G., Mol, B. W., O’Connell, N. E., Parker, L., Redman, B. K., Seidler, A. L., Sheldrick, K. A., Sydenham, E., Torgerson, D. J., Wely, M. v., Wang, R., Bero, L., Kirkham, J. J.
BMJ Open
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1101/2023.09.21.23295626
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/23873/1/Wilkinson_etal_BMJO_Protocol_development_tool_VOR.pdf
A randomized trial alerting authors, with or without co-authors or editors, that research they cited in systematic reviews and guidelines has been retracted
2024 - Published
Avenell, A., Bolland, M. J., Gamble, G. D., Grey, A.
Accountability in Research, vol. 31, no. 1, pp. 14-37
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1080/08989621.2022.2082290
Designing financial incentives for health behaviour change: a mixed-methods case study of weight loss in men with obesity
2024 - Published
van der Pol, M., Mcdonald, M., Collacott, H. E., Dombrowski, S., Harris, F., Kee, F., Avenell, A., Gray, C., Skinner, R., Hoddinott, P.
Journal of Public Health, vol. 32, no. 1, pp. 65-77
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1007/s10389-022-01785-1
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/20955/2/vanderPol_etal_JPH_Designing_Financial_Incentives_VOR.pdf
- [ONLINE] View publication in Scopus
Ten years later: assessments of the integrity of publications from one research group with multiple retractions
2023 - E-pub ahead of print
Grey, A., Bolland, M. J., Avenell, A.
Accountability in Research
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1080/08989621.2023.2295996
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/22525/1/Grey_etal_AIR_Ten_Years_Later_AAM.pdf.docx
- [ONLINE] View publication in Scopus
Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial
2023 - Published
Ahmed, I., Hudson, J., Innes, K., Hernández, R., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
BMJ, vol. 383, e075383
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1136/bmj-2023-075383
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/22384/1/Ahmed_etal_BMJ_Effectiveness_of_COnservative_VoR.pdf
Letter to the editor: Validity of tests for publication integrity
2023 - Published
Bolland, M. J., Avenell, A., Grey, A.
International Journal of Gynecology & Obstetrics, vol. 163, no. 3, pp. 1043-1044
Contributions to Journals: Letters
- [ONLINE] DOI: https://doi.org/10.1002/ijgo.15182
Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia – analyses from the LACE randomised controlled trial
2023 - Published
Bashir, T., Achison, M., Adamson, S., Akpan, A., Aspray, T. J., Avenell, A., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Hume, C. L., Jackson, T., Kerr, S., Kilgour, A. H. M., Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Rossios, C., Sayer, A. A., Smith, K. T., Soiza, R., Steves, C. J., Struthers, A. D., Tiwari, D., Whitney, J., Witham, M. D., Kemp, P. R.
PloS ONE, vol. 18, no. 11 November, e0294330
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0294330
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/22721/1/Bashir_etal_PO_Activin_type_1_VoR.pdf
- [ONLINE] View publication in Scopus
ACE I/D genotype associates with strength in sarcopenic men but not with response to ACE inhibitor therapy in older adults with sarcopenia: Results from the LACE trial
2023 - Published
Rossios, C., Bashir, T., Adamson, S., Adamson, S., Akpan, A., Aspray, T. J., Avenell, A., Band, M. M., Burton, L. A., Cvoro, V., Donnan, P. T., Duncan, G. W., George, J., Gordon, A. L., Gregson, C. L., Hapca, A., Hume, C. L., Jackson, T. A., Kerr, S., Kilgour, A. H. M., Masud, T., McKenzie, A., McKenzie, E., Patel, H., Pilvinyte, K., Roberts, H. C., Sayer, A. A., Smith, K. T., Soiza, R., Steves, C. J., Struthers, A. D., Tiwari, D., Whitney, J., Witham, M. D., Kemp, P. R.
PloS ONE, vol. 18, no. 10, e0292402
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1371/journal.pone.0292402
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/22749/1/Rossios_etal_PO_ACE_ID_Genotype_VoR.pdf
Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions
2023 - Published
Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Alfirevic, Z., Avenell, A., Barbour, V., Brown, N. J. L., Carlisle, J., Clarke, M., Dicker, P., Dumville, J., Grey, A., Gurrin, L. C., Hayden, J. A., Heathers, J., Hunter, K. E., Lasserson, T., Lensen, S., Li, T., Li, W., Loder, E., Lundh, A., Meyerowitz-Katz, G., Mol, B. W., O' Connell, N. E., Parker, L., Redman, B. K., Seidler, A. L., Sheldrick, K. A., Sydenham, E., Torgerson, D. J., van Wely, M., Wang, R., Bero, L., Kirkham, J. J., Lam, E.
Working Papers: Preprint Papers
- [ONLINE] DOI: https://doi.org/10.1101/2023.09.21.23295626
Responses to concerns raised about publications don’t address the concerns raised
2023 - Published
Bolland, M. J., Avenell, A., Grey, A.
British Journal of Pain, vol. 17, no. 5, pp. 426-427
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1177/20494637231198757
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/22180/1/Bolland_etal_BJP_Response_to_Concerns_VOR.pdf
- [ONLINE] View publication in Scopus
The effect of weight loss interventions for obesity on fertility and pregnancy outcomes: a systematic review and meta-analysis
2023 - Published
Boyle, B. R., Ablett, A. D., Ochi, C., Hudson, J., Watson, L., Rauh, D., Avenell, A.
International Journal of Gynecology and Obstetrics, vol. 161, no. 2, pp. 335-342
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1002/ijgo.14597
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/20678/1/Boyle_etal_IJGO_Effect_weight_loss_VOR.pdf
Analysis of cluster randomised trials as if they were individually randomised
2023 - Published
Bolland, M. J., Avenell, A., Grey, A.
The lancet. Diabetes & endocrinology, vol. 11, no. 2, pp. 75
Contributions to Journals: Comments and Debates
- [ONLINE] DOI: https://doi.org/10.1016/S2213-8587(22)00363-1
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/21279/1/Bolland_etal_TLDE_Analysis_Of_Cluster_AAM.pdf
- [ONLINE] View publication in Scopus

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Update

Biography

Current Research

Investigating Health Professionals’ Perspectives and Experiences of Food Security-Related Conversations in Diabetes Care

Laparoscopic cholecystectomy versus conservative management for uncomplicated symptomatic gallstones: economic evaluation based on the C-GALL trial

A survey of experts to identify methods to detect problematic studies: Stage 1 of the INSPECT-SR Project

Barriers to investigating and reporting research misconduct: prioritising publication integrity

Association of bradykinin receptor 2 (BDKRB2) variants with physical performance and muscle mass: findings from the LACE sarcopenia trial

How to improve assessments of publication integrity

Text Messages With Financial Incentives for Men With Obesity: A Randomized Clinical Trial

Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT

Statistical Techniques to Assess Publication Integrity in Groups of Randomised Trials: A Narrative Review

Guidance on terminology, application, and reporting of citation searching: the TARCiS statement

A survey of experts to identify methods to detect problematic studies: Stage 1 of the INSPECT-SR Project

Publication integrity: what is it, why does it matter, how it is safeguarded and how could we do better?

Letter to the editor concerning "characteristics of baseline frequency data in spinal RCTs do not suggest widespread non-random allocation" by MMS Levayer, et al. (Eur Spine J; 2023; 32: 3009-3014)

Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions

A randomized trial alerting authors, with or without co-authors or editors, that research they cited in systematic reviews and guidelines has been retracted

Designing financial incentives for health behaviour change: a mixed-methods case study of weight loss in men with obesity

Ten years later: assessments of the integrity of publications from one research group with multiple retractions

Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial

Letter to the editor: Validity of tests for publication integrity

Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia – analyses from the LACE randomised controlled trial

ACE I/D genotype associates with strength in sarcopenic men but not with response to ACE inhibitor therapy in older adults with sarcopenia: Results from the LACE trial

Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions

Responses to concerns raised about publications don’t address the concerns raised

The effect of weight loss interventions for obesity on fertility and pregnancy outcomes: a systematic review and meta-analysis

Analysis of cluster randomised trials as if they were individually randomised

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