![Professor Dana Dawson Professor Dana Dawson](/img/200x200/staffpages/uploads/mmd950/DD2013.jpg)
DM, FRCP, D.Phil, FESC
Chair in Cardiovascular Medicine
- About
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- Email Address
- dana.dawson@abdn.ac.uk
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Professor Dawson qualified in medicine at University of Medicine “Grigore T. Popa”, Iasi, Romania. After completing her MRCP with the Royal College of Physicians in London and read for a D. Phil in Cardiovascular Medicine at Merton College, University of Oxford, she trained in Cardiovascular Medicine in Edinburgh, Oxford and London in the UK and at the University of Virginia, Charlottesville, in the USA. In 2010 she moved to the University of Aberdeen and Aberdeen Royal Infirmary where she currently is Professor of Cardiovascular Medicine and Consultant Cardiologist.
She made a significant contribution in advancing knowledge in acute stress induced (Takotsubo) cardiomyopathy, having delivered several landmark mechanistic clinical trials. Takotsubo studies are ongoing in Aberdeen who lead the Scottish Takotsubo Registry which has been accruing all cases since 2010.
There is keen interest in other topics such as exercise based interventions and pharmacological therapies to improve cardio-metabolic health in patients with type 2 diabetes, mechanistic trials unmasking heart failure in patients with COPD, deep cardiac phenotyping and strategies for prevention of cardio-toxicity in cardio-oncology. A cardio-dentistry collaboration explores the causal role of pathobionts in acute myocardial infarction.
Together with cardiac MR physicists, the group have developed the world's first cardiac array coil for cardiac Field Cycling Magnetic Resonance to investigate the unique characteristics of the heart muscle visible at low field and field cycling domains.
Professor Dana Dawson leads the Cardiology and Cardiovascular Research Unit who have strong collaborative links with many other UK centres, participating in multi-centre clinical research studies.
Memberships and Affiliations
- Internal Memberships
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Team members and close collaborators:
Dr. David Gamble - BHF Clinical Research Fellow, Clinical Lecturer
Dr. Hilal Khan - Clinical Research Fellow
Dr. Susanth Alapati - BHF Clinical (Dental) Research Fellow
Dr Sara Sharif - Elphinstone Clinical (Dental) Research Fellow
Ms Amelia Rudd, MSc - BHF AHP Clinical Research Fellow
Miss Lesley Cheyne - Cardiovascular Technician
Ms Janaki Srivanasan – Senior Research Sonographer
Dr. Lionel Broche – Lecturer in Fast Field Cycling MR Physics
Dr. Gareth Davies - Fast Field Cycling MR Physics Research Fellow
Dr. James Ross - Lecturer in Cardiovascular Magnetic Resonance Physics
Dr. Caroline Scally – former BHF Clinical Research Fellow
Miss Nadine Godsman – former BHF non-clinical PhD student
Dr. Alice Mezincescu – Clinical Lecturer (former BHF Clinical Research Fellow)
Dr. Chaitanya Pradeep Joshi - former Clinical Research Fellow - Dental, Elphinstone Scholar
Dr. Hassan Abbas – BHF Clinical Research Fellow
Research Nurses:
RN Valerie Harries
RN Jocelyn Abernethy
RN Debbie Olaotan
RN Pauline Crozier
Research Radiographers:
Mr Mike Hendry (MRI)
Ms Nicola Crouch (MRI)
Ms Laura Reid (MRI)
Ms Michelle Mauchline (MRI)
Mrs Denise Forrest (CT)
Ms Louise Lamley (CT)
- External Memberships
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She is a member of the British Cardiovascular Society, American Heart Association, Fellow of the European Society of Cardiology, Chair of the Myocardial Function Working Group of the European Society of Cardiology and head of the Taskforce on Takotsubo within the Heart Failure Association of the European Society of Cardiology.
Prizes and Awards
Most recent mentored scientific investigations shortlisted for prize awards include:
1. Janaki Srivanasan – winner of the British Society of Echocardiography Young Investigator Research Prize, October 2016
2. Caroline Scally – finalist at the Early Career award, Society of Cardiovascular Magnetic Resonance, Washington, January 2017
3. Caroline Scally – finalist at the Samuel A Levine Young Investigator Award of the American Heart Association, Anaheim, CA, November 2017
4. Nadine Godsman – winner of the Young Investigator’s prize of the British Pharmacological Society – Pharmacology, December 2017 – London, England
5. Caroline Scally - finalist at the Melvin Judkins Young Investigator Award of the American Heart Association, Chicago, IL, November 2018
6. Alice Mezincescu – finalist at the Early Career Award-Translational Sciences of the Society of Cardiovascular Magnetic Resonance, Seattle, February 2019
7. Chaitanya Joshi – Coronary Artery Disease Risk is Increased by Periodontitis Pathobionts, winner of the Sir Wilfred Fish Prize of The British Society of Periodontology and Implant Dentistry, London, November 2021
8. Alice Mezincescu – Insulin Resistance in Type 2 Diabetes is Moderated by Saturated Fatty Acids Abundance and Turnover, finalist at the Early career award on Lifestyle and Cardiometabolic Risk, American Heart Association scientific sessions, Chicago, November 2022
9. Amelia Rudd - Cardiovascular and Non-Cardiovascular Prescribing and Mortality after Takotsubo - winner of the Scottish Cardiac Society Award, October 2023
- Research
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Funding and Grants
RESEARCH GRANTS – current:
1. A Randomised Controlled Trial of Renin-Angiotensin System Inhibition for Reduction of Cardiovascular Events after Takotsubo Cardiomyopathy (EVEREST), D Dawson (CI), DE Newby, G Hillis, M Petrie, G McCann, CP Gale, J Horowitz, G MacLennan, G Scotland, J Norrie – NIHR – Health Technology Assessment (NIHR157523), 01/01/25 to 31/12/31, £3,049,458.47
2. Myocardial Lipid Compartments in Type 2 Diabetes – Tenovus Scotland, AM Ciutac, J Ross, A Davidson and D Dawson, 1/08/2024-31/12/2025, £12,260
3. Sodium-glucose transporter type 2 inhibition in anthracycline-related cardiotoxicity, D Dawson (CI), D E Newby, BHF CRTF FS/CRTF/23/24508, 2025-2028, £363,697
4. Bioinformatics analysis of single cell SEQUENCing of Human PBMC in acutE cardiac disease- SEQUENCE study, H Khan, E Collie-Duguid, D Dawson, Tenovus Scotland, 03, 2023, £14,557
5. Replacement of (ultrasound) echocardiography equipment for clinical research, BHF Infrastructure Grant IG/F/21/50010 and IG/f/21/50010, D Dawson, 2022, £147,208
6. Epigenetic Phase Variation of Periodontal Bacteria – a Mechanistic Contributor to Coronary Artery Disease, BHFClinical Research Training Fellowship - FS/CRTF/22/24275 (for Dr Shirleen Hallang), K Hijazi (PI) and D Dawson, £217,509, 2022-2025, withdrawn due to unavailability of the fellow and re-awarded after peer review as a Project Grant, BHF PG/22/11117, £230,671
7. Epidemiology and predisposition of acute stress-induced (takotsubo) cardiomyopathy - BHF Research Training Fellowship (FS/RTF/20/30009, for Ms Amelia Rudd): D Dawson (CI), David Newby, 2021-2024, £215,051
8. The next leap in cardiac magnetic resonance imaging: cycling the field: D Dawson (CI), D Lurie, L Broche, J Ross, H Abbas: BHF New Horizons Grant no. NH/19/1/34595, 2020-2024, £277,722
- Publications
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An Update on Cardiac Magnetic Resonance Imaging in Takotsubo Cardiomyopathy
Current Cardiovascular Imaging Reports, vol. 13, no. 5, 17Contributions to Journals: Review articlesTakotsubo syndrome in Heart Failure and World Congress on Acute Heart Failure 2019: highlights from the experts
ESC Heart Failure, vol. 7, no. 2, pp. 400-406Contributions to Journals: Review articlesFast field-cycling magnetic resonance detection of intracellular ultra-small iron oxide particles in vitro: Proof-of-concept
Journal of Magnetic Resonance, vol. 313, 106722Contributions to Journals: ArticlesDeterminants of Exercise Capacity and Myocardial Perfusion Reserve in Asymptomatic Patients With Aortic Stenosis
JACC. Cardiovascular Imaging, vol. 13, no. 1 Part 1, pp. 178-180Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/j.jcmg.2019.08.008
- [ONLINE] View publication in Scopus
Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans
The American Journal of Clinical Nutrition, vol. 111, no. 1, pp. 79-89Contributions to Journals: ArticlesLifelong recurrent takotsubo cardiomyopathy: a case report
European Heart Journal - Case Reports, vol. 3, no. 4, pp. 1-5Contributions to Journals: ArticlesDistinct Subgroups in Hypertrophic Cardiomyopathy in the NHLBI HCM Registry
Journal of the American College of Cardiology, vol. 74, no. 19, pp. 2333-2345Contributions to Journals: ArticlesResponse by Scally and Dawson to Letters Regarding Article, “Myocardial and Systemic Inflammation in Acute StressInduced (Takotsubo) Cardiomyopathy”
Circulation, vol. 140, no. 13, pp. e698-e699Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.041878
- [ONLINE] View publication in Scopus
Reference range determination for imaging biomarkers: Myocardial T1
Journal of Magnetic Resonance Imaging, vol. 50, no. 3, pp. 771-778Contributions to Journals: ArticlesMatrix-dependent size modifications of iron oxide nanoparticles (Ferumoxytol) spiked into rat blood cells and plasma: Characterisation with TEM, AF4-UV-MALS-ICP-MS/MS and spICP-MS
Journal of Chromatography B, vol. 1124, pp. 356-365Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jchromb.2019.06.029
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14562/1/Matrix_dependent_iron_oxide_NPs_Kenneth_Nwoko.pdf
- [ONLINE] https://linkinghub.elsevier.com/retrieve/pii/S1570023219304842
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Aortic stiffness in aortic stenosis assessed by cardiovascular MRI: a comparison between bicuspid and tricuspid valves
European Radiology, vol. 29, no. 5, pp. 2340-2349Contributions to Journals: ArticlesDiastolic Ventricular Interaction in Heart Failure With Preserved Ejection Fraction
Journal of the American Heart Association, vol. 8, no. 7, e010114Contributions to Journals: ArticlesMyocardial and Systemic Inflammation in Acute Stress-Induced (Takotsubo) Cardiomyopathy
Circulation, vol. 139, no. 13, pp. 1581-1592Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438459/
- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.118.037975
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
- [ONLINE] http://europepmc.org/abstract/med/30586731
Takotsubo syndrome: State-of-the-art review by an expert panel – Part 2
Cardiovascular Revascularization Medicine, vol. 20, no. 2, pp. 153-166Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1016/j.carrev.2018.11.016
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Takotsubo syndrome: State-of-the-art review by an expert panel - Part 1
Cardiovascular revascularization medicine : including molecular interventions, vol. 20, no. 1, pp. 70-79Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1016/j.carrev.2018.11.015
- [ONLINE] View publication in Mendeley
Symptom Onset in Aortic Stenosis: Relation to Sex Differences in Left Ventricular Remodeling
JACC. Cardiovascular Imaging, vol. 12, no. 1, pp. 96-105Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jcmg.2017.09.019
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13761/1/Symptom_onset_in_aortic_stenosis.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Takotsubo: the myth of rapid and complete recovery
European Heart Journal, vol. 39, no. 42, pp. 3762-3763Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/eurheartj/ehy660
Response to Letters Regarding Article, "Persistent Long-Term Structural, Functional, and Metabolic Changes After Stress-Induced (Takotsubo) Cardiomyopathy"
Circulation, vol. 138, no. 9, pp. 962-963Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.118.035883
Complex roads from genotype to phenotype in dilated cardiomyopathy: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology
Cardiovascular Research, vol. 114, no. 10, pp. 1287-1303Contributions to Journals: ArticlesMetabolic changes in hypertrophic cardiomyopathies: Scientific update from the Working Group of Myocardial Function of the European Society of Cardiology
Cardiovascular Research, vol. 114, no. 10, pp. 1273-1280Contributions to Journals: ArticlesPreclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters
Contrast Media & Molecular Imaging, vol. 2018, 3064751Contributions to Journals: ArticlesRegional expression of inflammatory and cardiac remodelling genes in a rat model of takotsubo cardiomyopathy
Annual Conference of the British-Cardiovascular-Society on High Performing Teams, pp. A79-A80Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1136/heartjnl-2018-BCS.97
Persistent Long-Term Structural, Functional, and Metabolic Changes After Stress-Induced (Takotsubo) Cardiomyopathy
Circulation, vol. 137, no. 10, pp. 1039-1048Contributions to Journals: ArticlesThe innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC
European Journal of Heart Failure, vol. 20, no. 3, pp. 445-459Contributions to Journals: Review articlesAn integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology
European Journal of Heart Failure, vol. 20, no. 2, pp. 216-227Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/ejhf.1059
- [ONLINE] View publication in Scopus
Acute stress-induced (takotsubo) cardiomyopathy
Heart, vol. 104, no. 2, pp. 96-102Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1136/heartjnl-2017-311579
The Authors Reply
JACC. Cardiovascular Imaging, vol. 11, no. 1, pp. 154-155Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/j.jcmg.2017.11.004
Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials
International Journal of Cardiology, vol. 244, pp. 59-66Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ijcard.2017.06.040
Author's Reply: Persistence of Deformation Abnormalities and Detection of Fibrosis at 4-Month Follow-up in Patients with Takotsubo Syndrome
Journal of the American Society of Echocardiography, vol. 30, no. 10, pp. 1042-1042Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/j.echo.2017.07.002
Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention
Data in brief, vol. 14, pp. 197-205Contributions to Journals: ArticlesReport from the Annual Conference of the British Society of Echocardiography, November 2016, Queen Elizabeth II Conference Centre, London.
Echo research and practice, vol. 4, no. 3, pp. M1-M18Contributions to Journals: ArticlesInorganic Nitrate in Angina Study: A Randomized Double-Blind Placebo-Controlled Trial
Journal of the American Heart Association, vol. 6, no. 9, pp. 1-17Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1161/JAHA.117.006478
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/9423/1/e006478.full.pdf
Alterations in Cardiac Deformation, Timing of Contraction and Relaxation, and Early Myocardial Fibrosis Accompany the Apparent Recovery of Acute Stress-Induced (Takotsubo) Cardiomyopathy: An End to the Concept of Transience
Journal of the American Society of Echocardiography, vol. 30, no. 8, pp. 745-755Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.echo.2017.03.016
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10558/1/JASE_7503R3.pdf
- [ONLINE] http://europepmc.org/abstract/med/28599831
Isolated cardiac desminopathy
European heart journal cardiovascular Imaging, vol. 18, no. 7, pp. 822Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/ehjci/jex049
Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by (1)H NMR spectroscopy
Bioorganic & Medicinal Chemistry, vol. 25, no. 10, pp. 2730-2742Contributions to Journals: ArticlesComparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) Study
European Heart Journal, vol. 38, no. 16, pp. 1222–1229Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/eurheartj/ehx001
Duration of dual antiplatelet therapy in acute coronary syndrome
Heart, vol. 103, no. 8, pp. 573-580Contributions to Journals: Review articlesA randomized double-blind placebo-controlled crossover trial of sodium nitrate in patients with stable angina INAS
Future cardiology, vol. 12, no. 6, pp. 617-626Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.2217/fca-2016-0026
The Authors Reply: Reply to 'Right Ventricle Involvement in Tako-Tsubo Cardiomyopathy'
JACC. Cardiovascular Imaging, vol. 9, no. 5, pp. 633-633Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/j.jcmg.2015.02.032
The Authors Reply: Reply to 'Is the Heart Really Stressed Out of Energy?'
JACC. Cardiovascular Imaging, vol. 9, no. 5, pp. 635-636Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.1016/j.jcmg.2015.03.015
Response to Letter Regarding Article, "the Effect of Selective Heart Rate Slowing in Heart Failure with Preserved Ejection Fraction"
Circulation, vol. 133, no. 16, pp. e604Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.116.021488
- [ONLINE] View publication in Scopus
Right Ventricular Involvement and Recovery after Acute Stress-Induced (Tako-tsubo) Cardiomyopathy
The American Journal of Cardiology, vol. 117, no. 5, pp. 775-780Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.amjcard.2015.11.057
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8261/1/AJC_D_15_02447R1.1.pdf
Myocardial Perfusion Reserve but not fibrosis predicts outcomes in initially asymptomatic patients with moderate to severe aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in AS study- PRIMID AS
Journal of Cardiovascular Magnetic Resonance, vol. 18, no. Supplement 1, O36Contributions to Journals: ArticlesT1 mapping for assessment of myocardial injury and microvascular obstruction at one week post myocardial infarction
European Journal of Radiology, vol. 85, no. 1, pp. 279-285Contributions to Journals: ArticlesThe Effect of Selective Heart Rate Slowing in Heart Failure with Preserved Ejection Fraction
Circulation, vol. 132, no. 18, pp. 1719-1725Contributions to Journals: ArticlesApical variant Tako-tsubo is associated with persistent myocardial strain dysfunction
Congress of the European-Society-of-Cardiology (ESC) 2015, pp. 943-944Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1093/eurheartj/ehv401
Tako-Tsubo Cardiomyopathy: A Heart Stressed Out of Energy?
JACC. Cardiovascular Imaging, vol. 8, no. 8, pp. 985-987Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/j.jcmg.2014.10.004
Selection of magnetization catalyzation and readout methods for modified Look-Locker inversion recovery: A T1 mapping primer
Magnetic Resonance Imaging, vol. 33, no. 4, pp. 363-373Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.mri.2015.02.004
Relation of Delayed Recovery of Myocardial Function After Takotsubo Cardiomyopathy to Subsequent Quality of Life
The American Journal of Cardiology, vol. 115, no. 8, pp. 1085-1089Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.amjcard.2015.01.541
Dynamic changes of the extracellular matrix after acute tako-tsubo cardiomyopathy
Journal of Cardiovascular Magnetic Resonance, vol. 17, no. Suppl. 1, P259Contributions to Journals: Abstracts