Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes
Mezincescu, A., Rudd, A. E., Cheyne, L., Horgan, G., Philip, S., Cameron, D., van Loon, L., Whitefield, P., Gribbin, R., Hu, M. K., Delibegovic, M., Fielding, B., Lobley, G., Thies, F., Newby, D. E., Gray, S., Henning, A., Dawson, D.
Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation
Leeson-Payne, A., Iyinikkel, J., Malcolm, C., Lam, B. Y. H., Sommer, N., Dowsett, G. K. C., Blanco Martinez de Morentin, P., Thompson, D., MacKenzie, A., Chianese, R., Kentistou, K. A., Gardner, E. J., Perry, J. R., Grassmann, F., Speakman, J., Rochford, J., Yeo, G. S. H., Murray, F., Heisler, L.
Dual-energy X-ray absorptiometry derived knee shape may provide a useful imaging biomarker for predicting total knee replacement: findings from a study of 37,843 people in UK Biobank.
Beynon, R., Saunders, F., Ebsim, R., Frysz, M., Faber, B., Gregory, J., Lindner, C., Sarmanova, A., Aspden, R. M., Harvey, N. C., Cootes, T., Tobias, J. H.
Osteoarthritis and Cartilage Open, vol. 6, no. 2, 100468
A single-cell atlas enables mapping of homeostatic cellular shifts in the adult human breast
Reed, A. D., Pensa, S., Steif, A., Stenning, J., Kunz, D. J., Porter, L. J., Hua, K., He, P., Twigger, A., Siu, A. J. Q., Kania, K., Barrow-McGee, R., Goulding, I., Gomm, J. J., Speirs, V., Jones, J. L., Marioni, J. C., Khaled, W. T.
LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy
Schwab, K., Frahm, S., Magbagbeolu, M., Horsley, D., Goatman, E., Melis, V., Theuring, F., Ishaq, A., Storey, J. M. D., Harrington, C., Wischik, C., Riedel, G.
A novel method to quantify fibrin–fibrin and fibrin–α2-antiplasmin cross-links in thrombi formed from human trauma patient plasma
Morrow, G. B., Flannery, S., Charles, P. D., Heilig, R., Feller, T., McQuilten, Z., Wake, E., Ariens, R. A. S., Winearls, J., Mutch, N. J., Fischer, R., Laffan, M. A., Curry, N.
Allopurinol and Blood Pressure Variability Following Ischemic Stroke and Transient Ischemic Attack: A Secondary Analysis of XILO-FIST
MacDonald, A. S., McConnachie, A., Dickie, D. A., Bath, P. M., Forbes, K., Quinn, T. J., Broomfield, N. M., Dani, K. A., Doney, A. S. F., Muir, K. W., Struthers, A., Walters, M. R., Barber, M., Bhalla, A., Cameron, A., Guyler, P., Hassan, A., Kearney, M. T., Keegan, B. C., Sekaran, L., Macleod, M., Randall, M., Shaw, L., Subramanian, G., Werring, D. J., Dawson, J.
Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity. Peptides
Ghazal, A., Clarke, D. J., Abdel-Rahman, M. A., Ribeiro, A., Collie-Duguid, E., Pattinson, C., Burgoyne, K., Muhammad, T., Alfadhel, S. M., Heidari, Z., Samir, R., Gerges, M., Nkene, I., Colamarino, R. A., Hijazi, K., Houssen, W. E.
Aberrant miR-29 is a predictive feature of severe phenotypes in pediatric Crohn’s disease
Shumway, A. J., Shanahan, M. T., Hollville, E., Chen, K., Beasley, C., Villanueva, J. W., Albert, S., Lian, G., Cure, M. R., Schaner, M., Zhu, L. C., Bantumilli, S., Deshmukh, M., Furey, T. S., Sheikh, S. Z., Sethupathy, P.
A CO2 sensing module modulates β-1,3-glucan exposure in Candida albicans.
Avelar, G. M., Pradhan, A., Ma, Q., Hickey, E., Leaves, I., Liddle, C., Rodriguez Rondon, A. V., Kaune, A., Shaw, S., Maufrais, C., Sertour, N., Bain, J. M., Larcombe, D. E., de Assis, L. J., Netea, M. G., Munro, C. A., Childers, D. S., Erwig, L. P., Brown, G. D., Gow, N. A. R., Bougnoux, M., d'Enfert, C., Brown, A. J. P.
Characterizing the Neurobiological Mechanisms of Action of Exercise and Cognitive–Behavioral Interventions for Rheumatoid Arthritis Fatigue: a magnetic resonance imaging brain study
Dehsarvi, A., Al-Wasity, S., Stefanov, K., Wiseman, S. J., Ralston, S., Wardlaw, J., Emsley, R., Bachmair, E., Cavanagh, J., Waiter, G., Basu, N.
Association between pre-stroke comorbidity and post-stroke prescribing in a Scottish ischaemic stroke survivor population: A national data linkage study
Sterling, K., Macleod, M., Turner, M.
18th UK Stroke Forum Conference 2023, pp. 122-122
Contributions to Journals: Abstracts
Assessment of the Teratogenic Effect of Drugs on the Chicken Embryo
Rosa Fraga, L., de Oliveira, M. R., Wermann, K. M., Vargesson, N.
Teratogenicity Testing: Methods and Protocols. 2 edition. Springer, pp. 251-260, 10 pages
Chapters in Books, Reports and Conference Proceedings: Chapters
An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans
McEwan, A. R., Hing, B., Erickson, J. C., Hutchings, G., Urama, C., Norton-Hughes, E., D'Ippolito, M., Berry, S., Delibegovic, M., Grassmann, F., MacKenzie, A.
Femoral Neck Width Genetic Risk Score is A Novel Independent Risk Factor for Hip Fractures
Tobias, J. H., Nethander, M., Faber, B. G., Heppenstall, S. V., Ebsim, R., Cootes, T., Lindner, C., Saunders, F., Gregory, J., Aspden, R. M., Harvey, N. C., Kemp, J. P., Frysz, M., Ohlsson, C.
The atypical 'hippocampal' glutamate receptor coupled to phospholipase D that controls stretch-sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
Thompson, K. J., Watson, S., Zanato, C., Dall'Angelo, S., De Nooij, J. C., Pace-Bonello, B., Shenton, F. C., Sanger, H. E., Heinz, B. A., Broad, L. M., Grosjean, N., McQuillian, J. R., Dubini, M., Pyner, S., Greig, I., Zanda, M., Bleakman, D., Banks, R. W., Bewick, G. S.
Experimental Physiology, vol. 109, no. 1, pp. 81-99
In utero exposures to perfluoroalkyl substances and the human fetal liver metabolome in Scotland: a cross-sectional study
Hyötyläinen, T., McGlinchey, A., Salihovic, S., Schubert, A., Douglas, A., Hay, D. C., O'Shaughnessy, P. J., Iredale, J. P., Shaw, S., Fowler, P. A., Orešič, M.
The Lancet Planetary Health, vol. 8, no. 1, pp. e5-e17
Small-molecule Targeting AMPA-mediated Excitotoxicity Has Therapeutic Effects in Mouse Models for Multiple Sclerosis
Zhai, D., Yan, S., Samsom, J., Wang, L., Su, P., Jiang, A., Zhang, H., Jia, Z., Wallach, I., Heifets, A., Zanato, C., Tseng, C., Wong, A. H. C., Greig, I., Liu, F.
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy
Smyth, P., Ferguson, L., Burrows, J. F., Burden, R. E., Tracey, S. R., Herron, M., Kovaleva, M., Williams, R., Porter, A. J., Longley, D. B., Barelle, C. J., Scott, C. J.
Enfortumab Vedotin and Pembrolizumab as Monotherapies and Combination Treatment in Locally Advanced or Metastatic Urothelial Carcinoma: A Narrative Review
Bantounou, M. A., Plascevic, J., MacDonald, L., Wong, M. C., O'Connell, N., Galley, H.
Advancements, deficiencies, and future necessities of studying Saprolegniales: A semi-quantitative review of 1073 published papers
Masigol, H., van West, P., Taheri, S. R., Fregeneda-Grandes, J. M., Pârvulescu, L., McLaggan, D., Bliss, T. T., Mostowfizadeh-Ghalamfarsa, R., Pourmoghaddam, M. J., Grossart, H. P.
Management of the Rectal Stump after Subtotal Colectomy Operations for Inflammatory Bowel Disease in the Era of Immunologic Therapy: A Two-Centre Cohort Study
Boldovjakova, D., El-Abbassy, I., Alarcon, I., El-Saify, M., Chan, J. H., Harley, M., Parnaby, C., Watson, A., Ramsay, G.
Journal of Digestive Diseases, vol. 41, no. 6, pp. 872–878
Significant dose-dependent reduction in neurofilament light chain concentration in plasma with oral tau aggregation inhibitor hydromethylthionine mesylate
Wischik, C. M., Schelter, B., Penny, L. K., Miller, S., Stefanacci, R., Heslegrave, A., Zetterberg, H.
Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer
Chatterji, S., Niehues, J. M., van Treeck, M., Loeffler, C. M. L., Saldanha, O. L., Veldhuizen, G. P., Cifci, D., Carrero, Z. I., Abu-Eid, R., Speirs, V., Kather, J. N.
Functional filter for whole genome sequencing data identifies HHT and stress-associated non-coding SMAD4 polyadenylation site variants >5kb from coding DN
Xiao, S., Kai, Z., Murphy, D., Li, D., Patel, D., Bielowka, A., Bernabeu-Herrero, M. E., Abdulmogith, A., Mumford, A. D., Westbury, S., Aldred, M. A., Vargesson, N., Caulfield, M. J., Genomics England Research Consortium, Shovlin, C. L.
American Journal of Human Genetics, vol. 110, no. 11, pp. 1903-1918
BMP signalling: A significant player and therapeutic target for osteoarthritis
Jaswal, A. P., Kumar, B., Roelofs, A. J., Iqbal, S. F., Singh, A. K., Riemen, A. H. K., Wang, H., Ashraf, S., Nanasaheb, S. V., Agnihotri, N., De Bari, C., Bandyopadhyay, A.
Osteoarthritis and Cartilage, vol. 31, no. 11, pp. 1454-1468
Disruption of VEGFR signaling leading to developmental defects
Knudsen, T. B., Saili, K., Franzosa, J., Baker, N., Spencer, R., Tal, T., Kleinstreuer, N., Heinonen, T., Ellis-Hutchings, R., Vargesson, N., Bondesson, M.
Organisation for Economic Co-Operation and Development (OECD). 62 pages
Impaired Cardiac and Skeletal Muscle Energetics Following Anthracycline Therapy for Breast Cancer
Gamble, D. T., Ross, J., Khan, H., Unger, A., Cheyne, L., Rudd, A., Saunders, F., Srivanasan, J., Kamya, S., Horgan, G., Hannah, A., Baliga, S., Tocchetti, C. G., Urquhart, G., Linke, W. A., Masannat, Y., Mustafa, A., Fuller, M., Elsberger, B., Sharma, R., Dawson, D.
Circulation. Cardiovascular imaging, vol. 16, no. 10, pp. 817-826
A 20-year population study of peripartum cardiomyopathy
Jackson, A. M., Macartney, M., Brooksbank, K., Brown, C., Dawson, D., Francis, M., Japp, A., Lennie, V., Leslie, S. J., Martin, T., Neary, P., Venkatasubramanian, S., Vickers, D., Weir, R. A., McMurray, J. J. V., Jhund, P. S., Petrie, M. C.
European Heart Journal, vol. 44, no. 48, pp. 5128-5141
Trends in intracerebral haemorrhage admissions, prior anticoagulant use, acute stroke care, and mortality outcomes 2011-2018:: A national Scottish database study.
Sterling, K., Macleod, M., Turner, M., Barber, M.
8th World Intracranial Hemorrhage Conference (WICH 2023), pp. 1-107
Low‐field MRI: A report on the 2022 ISMRM workshop
Campbell‐washburn, A. e., Keenan, K. e., Hu, P., Mugler, J. p., Nayak, K. s., Webb, A. g., Obungoloch, J., Sheth, K. n., Hennig, J., Rosen, M. s., Salameh, N., Sodickson, D. k., Stein, J. m., Marques, J. p., Simonetti, O. p.
Magnetic Resonance in Medicine, vol. 90, no. 4, pp. 1682-1694
Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history and potential treatments from translation to clinical trials
Krishnan, K., Campos, P. B., Nguyen, T. N., Tan, W., Chan, S. L., Appleton, J. P., Law, Z. K., Hollingworth, M., Kirkman, M., England, T. J., Roffe, C., Macleod, M., Dawson, J., Bayraktutan, U., Werring, D. J., Sprigg, N., Bath, P. M.
Nebulized Recombinant Tissue Plasminogen Activator (rt-PA) for Acute COVID-19-Induced Respiratory Failure: An Exploratory Proof-of-Concept Trial
Chowdary, P., Agarwal, B., Peralta, M. R., Bhagani, S., Lee, S., Goldring, J., Lipman, M., Waqif, E., Phillips, M., Philippou, H., Foley, J. H., Mutch, N. J., Ariëns, R. A. S., Stringer, K. A., Ricciardi, F., Watissée, M., Hughes, D., Nathwani, A., Riddell, A., Patch, D., Buckley, J., De Neef, M., Dimber, R., Diaz-Garcia, C., Patel, H., Nandani, A., Dissanayake, U., Chadwick, N., Alkhatip, A. A. A. M. M., Watkinson, P., Raith, E., Singh, S., Wolff, T., Jha, R., Brill, S. E., Bakhai, A., Evans, A., Gilani, F., Gomez, K.
Journal of Clinical Medicine, vol. 12, no. 18, 5848
Novel therapeutics and emerging technology in haemostasis and thrombosis: highlights from the British society for haemostasis and thrombosis annual meeting
Whyte, C. S., Morrow, G. B., Gauer, J. S., Montague, S. J., Nicolson, P. L. R.
Frontiers in cardiovascular medicine, vol. 10, 1225243.
The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses
Faber, B. G., Frysz, M., Boer, C. G., Evans, D. S., Ebsim, R., Flynn, K. A., Lundberg, M., Southam, L., Hartley, A. E., Saunders, F., Lindner, C., Gregory, J., Aspden, R. M., Lane, N. E., Harvey, N. C., Evans, D. M., Zeggini, E., Smith, G. D., Cootes, T. F., van Meurs, J. B., Kemp, J. P., Tobias, J. H.
Phase II randomised, placebo-controlled, clinical trial of interleukin-1 receptor antagonist in intracerebral haemorrhage: BLOcking the Cytokine IL-1 in ICH (BLOC-ICH)
Parry-Jones, A. R., Stocking, K., MacLeod, M. J., Clarke, B., Werring, D. J., Muir, K. W., Vail, A.
European Stroke Journal , vol. 8, no. 3, pp. 819-827