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Dr Samantha Wileman

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Dr Samantha Wileman
Dr Samantha Wileman
Dr Samantha Wileman

BSc(Hons), PhD

Advanced Research Fellow

About
Email Address
s.wileman@abdn.ac.uk
Office Address

Health Services Research Unit (HSRU)
3rd Floor, Health Sciences Building
University of Aberdeen
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition
Twitter
ResearchGate
Pure
Personal Website

Biography

I am currently the HSRU/CHaRT Quality Assurance (QA) manager. I joined the Unit in October 1997, as a Research Fellow on the Seasonal Affective Disorder (SAD) study; a randomised trial to evaluate the effectiveness of light therapy in primary care. I then worked as the trial co-ordinator on the REFLUX  trial, a national multicentre trial that looked at the best form of treatment for gastro-oesophageal reflux disease (GORD).

As the HSRU and CHaRT quality assurance (QA) manager, I take responsibility for developing robust QA systems, integrating them in to the Units current best working practices.

Qualifications

  • BSc Biochemistry and Physiology 
    1992 - University of Reading 
  • PhD Vascular Physiology 
    1995 - University of London, King's College London 

Memberships and Affiliations

Internal Memberships

Staff Development Group (HSRU representative, 2013 - present)

Clinical Research Operational Group (CROG; CHaRT representative, 2010 - present)

External Memberships

UKCRC Registered CTU Network Quality Assurance Group (CHaRT representative, 2008 - present)

UKCRC Registered CTU Network Monitoring Task & Finish Group (CHaRT representative, 2019 -present)

Registered member of the Research Quality Association (RQA; 2008-present)

Registered member of the Institute of Clinical Research (ICR; 2007-present) 

Latest Publications

View My Publications

Prizes and Awards

Certificate of Excellence 2021 Winner: Principal's Prizes for Research & Engagement; Public Engagement with Research Award (Biomedical)

Research

Research Areas

Applied Health Sciences

View Research Area

Research Specialisms

  • Quality Management

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Current Research

QA and studies within the CHaRT portfolio.

 

Past Research

The REFLUX trial and SAD study.

Knowledge Exchange

Actively involved in HSRU's Public Engagement Group 

 

Teaching

Courses

Publications

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  • The UK resuscitative endovascular balloon occlusion of the aorta in trauma patients with life-threatening torso haemorrhage: The (UK-REBOA) multicentre RCT

    Jansen, J. O., Hudson, J., Kennedy, C., Cochran, C., Maclennan, G., Gillies, K., Lendrum, R., Sadek, S., Boyers, D., Ferry, G., Lawrie, L., Nath, M., Cotton, S., Wileman, S., Forrest, M., Brohi, K., Harris, T., Lecky, F., Moran, C., Morrison, J. J., Norrie, J., Paterson, A., Tai, N., Welch, N., Campbell, M. K., UK-REBOA Study Group
    Health Technology Assessment, vol. 28, no. 54
    Contributions to Journals: Articles

  • Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT

    Innes, K., Ahmed, I., Hudson, J., Hernández, R. A., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
    Health Technology Assessment, vol. 28, no. 26, pp. 1-151
    Contributions to Journals: Articles

  • Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial

    Ahmed, I., Hudson, J., Innes, K., Hernández, R., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
    BMJ, vol. 383, e075383
    Contributions to Journals: Articles

  • Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients with Exsanguinating Hemorrhage: The UK-REBOA Randomized Clinical Trial

    Jansen, J. O., Hudson, J., Cochran, C., MacLennan, G., Lendrum, R., Sadek, S., Gillies, K., Cotton, S., Kennedy, C., Boyers, D., Ferry, G., Lawrie, L., Nath, M., Wileman, S., Forrest, M., Brohi, K., Harris, T., Lecky, F., Moran, C., Morrison, J. J., Norrie, J., Paterson, A., Tai, N., Welch, N., Campbell, M. K., Aylwin, C., Bew, D., Brooks, A., Chinery, J., Cowlam, T., Frith, D., George, A., Hudson, A., Johnstone, P., Mahmood, A., Novak, A., O'Meara, M., Reid, S., Sattout, A., Smith, C., Stansfield, T., Thompson, J., UK-REBOA Study Group
    JAMA, vol. 330, no. 19, pp. 1862-1871
    Contributions to Journals: Articles

  • How to Deal with a Temporary Suspension and Restarting Your Trial: Our Experiences and lessons Learnt

    Constable, L., Davidson, T., Breeman, S., Cotton, S., McDonald, A., Wileman, S., Norrie, J.
    Trials, vol. 21, no. 1, pp. 765
    Contributions to Journals: Articles

  • Verifying participant-reported clinical outcomes: challenges and implications

    Breeman, S., Constable, L., Duncan, A., Starr, K., McDonald, A., Wileman, S., Cotton, S.
    Trials, vol. 21, no. 1, pp. 241
    Contributions to Journals: Articles

  • Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial

    Cooper, K., Breeman, S., Scott, N. W., Scotland, G., Clark, J., Hawe, J., Hawthorn, R., Phillips, K., MacLennan, G., Wileman, S., McCormack, K., Hernández, R. A., Norrie, J., Bhattacharya, S., HEALTH Study Group
    The Lancet, vol. 394, no. 10207, pp. 1425-1436
    Contributions to Journals: Articles

  • Laparoscopic supracervical hysterectomy compared with second-generation endometrial ablation for heavy menstrual bleeding: the HEALTH RCT

    Cooper, K., Breeman, S., Scott, N. W., Scotland, G. S., Hernández, R. A., Clark, T. J., Hawe, J., Hawthorn, R., Phillips, K., Wileman, S. M., McCormack, K., Norrie, J., Bhattacharya, S.
    Health Technology Assessment, vol. 23, no. 53, pp. 1-107
    Contributions to Journals: Articles

  • Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): Study protocol for a randomised controlled trial

    Constable, L., Cotterill, N., Cooper, D., Glazener, C., Drake, M. J., Forrest, M., Harding, C., Kilonzo, M., MacLennan, G., McCormack, K., McDonald, A., Mundy, A., Norrie, J., Pickard, R., Ramsay, C., Smith, R., Wileman, S., Abrams, P., The MASTER Study Group
    Trials, vol. 19, pp. 1-17
    Contributions to Journals: Articles

  • HEALTH: laparoscopic supracervical hysterectomy versus second-generation endometrial ablation for the treatment of heavy menstrual bleeding: study protocol for a randomised controlled trial

    Cooper, K., McCormack, K., Breeman, S., Wood, J., Scott, N. W., Clark, J., Hawe, J., Hawthorn, R., Phillips, K., Hyde, A., McDonald, A., Forrest, M., Wileman, S., Scotland, G., Norrie, J., Bhattacharya, S., HEALTH Study Group
    Trials, vol. 19, 63
    Contributions to Journals: Articles

  • Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial

    Brittenden, J., Cotton, S. C., Elders, A., Tassie, E., Scotland, G., Ramsay, C. R., Norrie, J., Burr, J., Francis, J., Wileman, S., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., MacLennan, G., Prior, M., Bolsover, D., Campbell, M. K.
    Health Technology Assessment, vol. 19, no. 27, pp. 1-342
    Contributions to Journals: Articles

  • A randomized trial comparing treatments for varicose veins

    Brittenden, J., Cotton, S. C., Elders, A., Ramsay, C. R., Norrie, J., Burr, J., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Francis, J., Tassie, E., Scotland, G., Wileman, S., Campbell, M. K.
    The New England Journal of Medicine, vol. 371, no. 13, pp. 1218-1227
    Contributions to Journals: Articles

  • Streamlining the study start up process

    Wileman, S., Norrie, J.
    2nd Clinical Trials Methodology Conference, pp. 1-1
    Contributions to Journals: Abstracts

  • Medical versus surgical management for gastro-oesophageal reflux disease (GORD) in adults

    Wileman, S. M., McCann, S., Grant, A. M., Krukowski, Z. H., Bruce, J.
    Cochrane Database of Systematic Reviews, no. 3, CD003243
    Contributions to Journals: Articles

  • Beliefs about surgery: Development and validation of an instrument to assess cognitive representations about surgery, in the context of a chronic illness

    Francis, J. J., Wileman, S. M., Bekker, H., Barton, G. R., Ramsay, C. R.
    Psychology & Health, vol. 24, no. 10, pp. 1125-1137
    Contributions to Journals: Articles

  • Minimal access surgery compared with medical management for chronic gastro-oesophageal reflux disease: UK collaborative randomised trial

    Grant, A. M., Wileman, S. M., Ramsay, C. R., Mowat, A. G., Krukowski, Z., Heading, R. C., Thursz, M. R., Campbell, M. K., REFLUX Trial Group
    British Medical Journal, vol. 337, a2664
    Contributions to Journals: Articles

  • Minimal access surgery compared with medical management for chronic gastro-oesophageal reflux disease: UK collaborative randomised trial

    Grant, A. M., Wileman, S. M., Ramsay, C. R., Mowat, N. A., Krukowski, Z. H., Heading, R. C., Thursz, M. R., Campbell, M. K., REFLUX Trial Group
    British Medical Journal, vol. 337, a2664
    Contributions to Journals: Articles

  • The effectiveness and cost-effectiveness of minimal access surgery amongst people with gastro-oesophageal reflux disease: a UK collaborative study. The REFLUX trial

    Grant, A. M., Wileman, S. M., Ramsay, C. R., Bojke, L., Epstein, D., Sculpher, M., Macran, S., Kilonzo, M. M., Vale, L. D., Francis, J., Mowat, A. G., Krukowski, Z. H., Heading, R., Thursz, M., Russell, I., Campbell, M. K., REFLUX Trial Group
    Health Technology Assessment, vol. 12, no. 31
    Contributions to Journals: Articles

  • Dates of birth and seasonal changes in well-being among 4904 subjects completing the seasonal pattern assessment questionnaire

    Eagles, J., Scott, N. W., Cameron, I. M., Wileman, S. M., Naji, S. A.
    Journal of Affective Disorders, vol. 104, no. 1-3, pp. 161-165
    Contributions to Journals: Articles

  • The development of a new measure of quality of life in the management of gastro-oesophageal reflux disease: The Reflux questionnaire

    Macran, S., Wileman, S., Barton, G., Russell, I., REFLUX Trial Group
    Quality of Life Research, vol. 16, no. 2, pp. 331-343
    Contributions to Journals: Articles

  • Role of l-citrulline transport in nitric oxide synthesis in rat aortic smooth muscle cells activated with LPS and interferon - gamma

    Wileman, S. M., Mann, G. M., Pearson, J. P., Baydoun, A. R.
    British Journal of Pharmacology, vol. 140, pp. 179-185
    Contributions to Journals: Articles

  • Use of healthcare services in seasonal affective disorder

    Eagles, J., Howie, F. L., Cameron, I. M., Wileman, S. M., Andrew, J. E., Robertson, C., Naji, S. A.
    British Journal of Psychiatry, vol. 180, no. 5, pp. 449-454
    Contributions to Journals: Articles

  • Seasonal affective disorder and social deprivation in Aberdeen

    Eagles, J., Andrew, J. E., Wileman, S. M., Howie, F. L., Cameron, I. M., Naji, S. A.
    Journal of Affective Disorders, vol. 70, no. 3, pp. 337-340
    Contributions to Journals: Articles

  • Comparison of consultation rates in primary care attenders with and without seasonal affective disorder

    Andrew, J. E., Wileman, S. M., Howie, F. L., Cameron, I. M., Naji, S. A., Eagles, J.
    Journal of Affective Disorders, vol. 62, no. 3, pp. 199-205
    Contributions to Journals: Articles

  • Light therapy for seasonal affective disorder in primary care: randomised controlled trial

    Wileman, S. M., Eagles, J., Andrew, J. E., Howie, F. L., Cameron, I. M., McCormack, K., Naji, S. A.
    British Journal of Psychiatry, vol. 178, pp. 311-316
    Contributions to Journals: Articles

  • Regulation of plasminogen activation by TGF-beta in cultured human retinal endothelial cells

    Wileman, S. M., Booth, N. A., Moore, N., Redmill, B., Forrester, J. V., Knott, R. M.
    British Journal of Ophthalmology, vol. 84, pp. 417-422
    Contributions to Journals: Articles

  • Transmembrane signalling mechanisms regulating expression of cationic amino acid transporters and inducible nitric oxide synthase in rat vascular smooth muscle cells

    Baydoun, A. R., Wileman, S. M., Wheeler-Jones, C. P., Marber, M. S., Mann, G. E., Pearson, J. D., Closs, E. I.
    Biochemical Journal, vol. 344, no. 1, pp. 265-272
    Contributions to Journals: Articles

  • A model system for the study of human retinal angiogenesis: activation of monocytes and endothelial cells and the association with the expression of the monocarboxylate transporter type 1 (MCT-1)

    Knott, R. M., Robertson, M., Muckersie, E., Folefac, V. A., Fairhurst, F. E., Wileman, S. M., Forrester, J. V.
    Diabetologia, vol. 42, pp. 870-877
    Contributions to Journals: Articles

  • Seasonal affective disorder among primary care attenders and a community sample in Aberdeen

    Eagles, J. M., Wileman, S. M., Cameron, I. M., Howie, F. L., Lawton, K., Gray, D. A., Andrew, J. E., Naji, S. A.
    British Journal of Psychiatry, vol. 175, pp. 472-475
    Contributions to Journals: Articles

  • Induction of L-arginine transport and nitric oxide synthase in vascular smooth muscle cells: synergistic actions of pro-inflammatory cytokines and bacterial lipopolysaccharide

    Wileman, S., Mann, G., Baydoun, A. R.
    British Journal of Pharmacology, vol. 116, no. 8, pp. 3243-50
    Contributions to Journals: Articles
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