Dityrosine Cross-links are Present in Alzheimer's Disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the Stability of the PHF-core Tau (297–391) In Vitro
Maina, M. B., Al-Hilaly, Y. K., Oakley, S., Burra, G., Khanom, T., Biasetti, L., Mengham, K., Marshall, K., Harrington, C. R., Wischik, C. M., Serpell, L. C.
Journal of Molecular Biology, vol. 434, no. 19, 167785
Oral Tau Aggregation Inhibitor for Alzheimer’s Disease: Design, Progress and Basis for Selection of the 16 mg/day Dose in a Phase 3, Randomized, Placebo-Controlled Trial of Hydromethylthionine Mesylate
Wischik, C. M., Bentham, P., Gauthier, S., Miller, S., Kook, K., Schelter, B. O.
Journal of Prevention of Alzheimer's Disease, vol. 9, pp. 780-790
Structural Identification of Individual Helical Amyloid Filaments by Integration of Cryo-Electron Microscopy-Derived Maps in Comparative Morphometric Atomic Force Microscopy Image Analysis
Lutter, L., Al-Hilaly, Y. K., Serpell, C. J., Tuite, M. F., Wischik, C. M., Serpell, L. C., Xue, W. F.
Journal of Molecular Biology, vol. 434, no. 7, 167466
Long-term hydromethylthionine treatment is associated with delayed clinical onset and slowing of cerebral atrophy in a pre-symptomatic P301S MAPT mutation carrier
Bentham, P., Staff, R. T., Schelter, B. O., Shiells, H., Harrington, C. R., Wischik, C. M.
Journal of Alzheimer's Disease, vol. 83, no. 3, pp. 1017-1023
Proteomic analysis of hydromethylthionine in the line 66 model of frontotemporal dementia demonstrates actions on tau-dependent and tau-independent networks
Schwab, K., Melis, V., Harrington, C. R., Wischik, C. M., Magbagbeolu, M., Theuring, F., Riedel, G.
