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The School of Biological Sciences

Dr Sharon Mitchell

Dr Sharon Mitchell
Dr Sharon Mitchell
Dr Sharon Mitchell

PhD (Aberdeen University 2002)

Advanced Research Fellow

About
Email Address
s.e.mitchell@abdn.ac.uk
Office Address

319, Zoology Building, Tillydrone Avenue, Aberdeen, AB24 2TZ

School/Department
School of Biological Sciences
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ORCiD
Pure

Biography

2015-date       Research Fellow, Lab Manager Energetics Research Group

Research

Research Overview

 

 

 

 

 

PhD Students

2016-date Megan Simpson

2016-2020 Jazmin Mendoza “Impacts of the thermic effect of food on feeding behaviour in mice: a test of the heat dissipation limits theory”

2015-2020 Emem Udoh PhD “Impacts of Calorie Restriction on Behaviour and Post-restriction Hyperphagia”

2015-2017 Heba Althubaiti “Fruit and Vegetable Intake and its Relationship with Health Parameters in Primary School Children”

Masters

2021-2022 Master of Science by Research Daniel Phillips “Bioinformatic Characterisation of Alternative Splicing in Three Different Tissues of Male C57BL/6 Mice Following Short-Term Graded Calorie Restriction"

2019-2020  MSci Daniel Phillips “Remodelling of three different tissues in the male C57BL/6 mouse during short-term graded caloric restriction is caused by tissue-specific variations in cell size and number”

2018-2019  MRes Stephanie Summers "The Impact of Short-Term Graded Calorie Restriction on Melanocortin-3 receptor (MC3R) Knockout Mice"

2013-2015 MSci  Megan Simpson “The effect of maternal age on offspring susceptibility to high fat diet induced obesity and offspring expression of hypothalamic obesity related genes”.

2011-2013 MRes Dawn Graham, “The Role of Neuropeptides and their Receptors in Response to Increased Hunger, Reduced Food Intake and Reduced Body Fat Content”.

2011-2013 MRes Nicole Culbert, “Does Hunger Neuropeptide and Energy Balance Manipulation Affect Metabolic Rate and Antioxidant Activity in C57BL/6 Mice under Caloric Restriction?”

Supervisor of a number of Erasmus Funded Internships from AgroSup, Djon, France.

Teaching

Teaching Responsibilities

Lab Skills in Biosciences (BI3812), co-coordinator with Cath Jones

Parasitology Field trip (BI25F3), co-coordinator with Jerry Sternberg

Supervisor for laboratory-based research projects for Honours students

 

Lecturer on following courses:

Environmental Physiology (ZO3513)

Principles of Animal Physiology (BI2510)

Diversity of Life 2 (BI1512)

Publications

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  • Limits to sustained energy intake XXIV: impact of suckling behaviour on the body temperatures of lactating female mice

    Gamo, Y., Bernard, A., Troup, C., Munro, F., Derrer, K., Jeannesson, N., Campbell, A., Gray, H., Miller, J., Dixon, J., Mitchell, S. E., Hambly, C., Vaanholt, L. M., Speakman, J. R.
    Scientific Reports, vol. 6, pp. 1-12
    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks

    Derous, D., Mitchell, S. E., Green, C. L., Wang, Y., Chen, L., Promislow, D. E. L., Lusseau, D., Speakman, J. R., Douglas, A.
    Aging, vol. 8, no. 4, pp. 917-931
    Contributions to Journals: Articles

  • CB1 receptor blockade counters age-induced insulin resistance and metabolic dysfunction

    Lipina, C., Vaanholt, L. M., Davidova, A., Mitchell, S. E., Storey-Gordon, E., Hambly, C., Irving, A. J., Speakman, J. R., Hundal, H. S.
    Aging Cell, vol. 15, no. 2, pp. 325-335
    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways

    Derous, D., Mitchell, S. E., Green, C. L., Chen, L., Han, J. J., Wang, Y., Promislow, D. E. L., Lusseau, D., Speakman, J. R., Douglas, A.
    Aging, vol. 8, no. 4, pp. 642-661
    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse

    Mitchell, S. E., Delville, C., Konstantopedos, P., Derous, D., Green, C. L., Wang, Y., Han, J. J., Promislow, D. E. L., Douglas, A., Chen, L., Lusseau, D., Speakman, J. R.
    Oncotarget, vol. 7, no. 15, pp. 19147-19170
    Contributions to Journals: Articles

  • Oxidative costs of reproduction: Oxidative stress in mice fed standard and low antioxidant diets

    Vaanholt, L. M., Milne, A., Zheng, Y., Hambly, C., Mitchell, S. E., Valencak, T. G., Allison, D. B., Speakman, J. R.
    Physiology and Behavior, vol. 154, pp. 1-7
    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: IV. Non-linear change in behavioural phenotype of mice in response to short-term calorie restriction

    Lusseau, D., Mitchell, S. E., Barros, C., Derous, D., Green, C., Chen, L., Han, J. J., Wang, Y., Promislow, D. E. L., Douglas, A., Speakman, J. R.
    Scientific Reports, vol. 5, 13198
    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: III. Impact of short term calorie and protein restriction on mean daily body temperature and torpor use in the C57BL/6 mouse

    Mitchell, S. E., Delville, C., Konstantopedos, P., Derous, D., Green, C. L., Chen, L., Han, J. J., Wang, Y., Promislow, D. E., Douglas, A., Lusseau, D., Speakman, J. R.
    Oncotarget, vol. 6, no. 21, pp. 18314-18337
    Contributions to Journals: Articles

  • Mice that are resistant to diet-induced weight loss have greater food anticipatory activity and altered melanocortin-3 receptor (MC3R) and Dopamine receptor 2 (D2) gene expression

    Vaanholt, L. M., Mitchell, S. E., Sinclair, R. E., Speakman, J. R.
    Hormones and Behavior, vol. 73, pp. 83-93
    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse

    Mitchell, S. E., Tang, Z., Kerbois, C., Delville, C., Konstantopedos, P., Bruel, A., Derous, D., Green, C., Aspden, R. M., Goodyear, S. R., Chen, L., Han, J. J. D., Wang, Y., Promislow, D. E. L., Lusseau, D., Douglas, A., Speakman, J. R.
    Oncotarget, vol. 6, no. 18, pp. 15902-15930
    Contributions to Journals: Articles

  • The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice

    Mitchell, S. E., Delville, C., Konstantopedos, P., Hurst, J., Derous, D., Green, C. L., Chen, L., Han, J. J., Wang, Y., Promislow, D. E. L., Lusseau, D., Douglas, A., Speakman, J. R.
    Oncotarget, vol. 6, no. 27, pp. 23213-23237
    Contributions to Journals: Articles

  • Factors influencing individual variability in high fat diet-induced weight gain in out-bred MF1 mice

    Vaanholt, L. M., Sinclair, R. E., Mitchell, S. E., Speakman, J. R.
    Physiology and Behavior, vol. 144, pp. 146-155
    Contributions to Journals: Articles

  • Effects of a specific MCHR1 antagonist (GW803430) on energy budget and glucose metabolism in diet-induced obese mice

    Zhang, L., Sinclair, R., Selman, C., Mitchell, S., Morgan, D., Clapham, J. C., Speakman, J. R.
    Obesity, vol. 22, no. 3, pp. 681-690
    Contributions to Journals: Articles

  • Limits to sustained energy intake. XXI. Effect of exposing the mother, but not her pups, to a cold environment during lactation in mice

    Valencak, T. G., Wright, P., Weir, A., Mitchell, S. E., Vaanholt, L. M., Hambly, C., Król, E., Speakman, J. R.
    Journal of Experimental Biology, vol. 216, no. 23, pp. 4326-4333
    Contributions to Journals: Articles

  • Limits to sustained energy intake. XX. Body temperatures and physical activity of female mice during lactation

    Gamo, Y., Troup, C., Mitchell, S. E., Hambly, C., Vaanholt, L. M., Speakman, J. R.
    Journal of Experimental Biology, vol. 216, no. 19, pp. 3751-3761
    Contributions to Journals: Articles

  • Limits to sustained energy intake. XVI. Body temperature and physical activity of female mice during pregnancy

    Gamo, Y., Bernard, A., Mitchell, S. E., Hambly, C., Al Jothery, A., Vaanholt, L. M., Król, E., Speakman, J. R.
    Journal of Experimental Biology, vol. 216, no. 12, pp. 2328-2338
    Contributions to Journals: Articles

  • Effects of Chronic Oral Rimonabant Administration on Energy Budgets of Diet-Induced Obese C57BL/6 Mice

    Zhang, L., Gamo, Y., Sinclair, R., Mitchell, S. E., Morgan, D. G., Clapham, J. C., Speakman, J. R.
    Obesity, vol. 20, no. 5, pp. 954-962
    Contributions to Journals: Articles

  • Physiological and behavioral responses to intermittent starvation in C57BL/6J mice

    Zhang, L., Mitchell, S. E., Hambly, C., Morgan, D. G., Clapham, J. C., Speakman, J. R.
    Physiology and Behavior, vol. 105, no. 2, pp. 376-387
    Contributions to Journals: Articles

  • Traversing the ovine cervix: a challenge for cryopreserved semen and creative science

    Robinson, J. J., McKelvey, W. A. C., King, M. E., Mitchell, S. E., Mylne, M. J. A., McEvoy, T. G., Dingwall, W. S., Williams, L.
    Animal , vol. 5, no. 11, pp. 1791-1804
    Contributions to Journals: Articles

  • Caloric Restriction

    Speakman, J. R., Mitchell, S. E.
    Molecular Aspects of Medicine, vol. 32, no. 3, pp. 159-221
    Contributions to Journals: Articles

  • The impact of acute caloric restriction on the metabolic phenotype in male C57BL/6 and DBA/2 mice

    Hempenstall, S., Picchio, L., Mitchell, S. E., Speakman, J. R., Selman, C.
    Mechanisms of Ageing and Development, vol. 131, no. 2, pp. 111-118
    Contributions to Journals: Articles

  • Dietary supplementation with conjugated linoleic acid plus n-3 polyunsatturated fatty acid increases food intake and brown adipose tissue in rats

    Sneddon, A. A., Rayner, D. V., Mitchell, S. E., Bashir, S., Ha, J., Wahle, K. W., Morris, A. C., Williams, L. M.
    Nutrients, vol. 1, no. 2, pp. 178-196
    Contributions to Journals: Articles

  • Leptin receptor gene expression and number in the brain are regulated by leptin level and nutritional status

    Mitchell, S. E., Nogueiras, R., Morris, A., Tovar, S., Grant, C., Cruickshank, M., Rayner, D. V., Dieguez, C., Williams, L. M.
    The Journal of Physiology, vol. 587, no. 14, pp. 3573-3585
    Contributions to Journals: Articles

  • The contribution of animal models to the study of obesity

    Speakman, J. R., Hambly, C., Mitchell, S. E., Król, E.
    Laboratory Animals, vol. 42, no. 4, pp. 413-432
    Contributions to Journals: Articles

  • The Lou/C rat is proportionally smaller than the Wistar and not anorexic or hyperactive as previously reported

    Hambly, C., Mitchell, S. E., Speakman, J. R., Williams, L.
    International Journal of Obesity, vol. 31, no. S1, pp. S84-S84
    Contributions to Journals: Abstracts
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