Gas Chromatography Mass Spectrometry (GCMS)
These instruments can be used to quantitate known metabolites of interest or identify unknowns in a sample matrix. They can also be used in a range of metabolic studies via determination of the stable isotopic enrichment of compounds of biological interest.
The section is equipped with:
- Thermo TSQ 9000 GC-MS/MS instrument with both electron impact (EI) and chemical ionization (PCI and NCI) capabilities. It is coupled to a TriPlus RSH autosampler and has headspace and SPME arrow technologies for analysis of volatile compounds.
- Thermo TSQ 7000 GC-MS instrument operates in electron impact (EI) mode.
It supports research in:
- Quantitative analysis e.g. amino acids in plasma or food extracts
- Principle component analysis
- Structural analysis – identification of unknowns
- Protein Metabolism
- Glucose kinetics
Recent studies have included work on:
- Type 2 diabetes prevention and maintenance
- Sustainable fish smoking techniques
- Sustainable proteins
- Oral Cancer research