Mr Gary Duncan
Research Technician
- Email Address
- gary.duncan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438669
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Gary has over 25 years of Mass Spectrometry experience. He started work at what was then the Rowett Research Institute in 1986, and after six weeks training in analytical techniques, started working in the Gas Isotope Ratio Mass Spectrometry (GIRMS) laboratory assisting Dr Brian McGaw and Mr Eric Milne. As interest in this technique grew, the lab eventually had four mass spectrometers dedicated to analysing the stable isotopes of Carbon, Hydrogen and Oxygen from a variety of biological sources, supporting research into energy expenditure and protein synthesis. The research programmes of the Rowett then required Liquid Chromatography Mass Spectrometry (LC/MS) and a MAT 900 double-sector LC-MS/MS system was purchased in 1998, along with a LaserMAT MALDI mass spectrometer. Initially his role was to develop techniques for sample analysis on the MALDI, but soon took over the role of managing the LC/MS mass facility. This coincided with a ‘take-off’ in the popularity of using LCMSMS in sample analysis, firstly in the growth of identifying proteins separated on 2D gels and more recently the targeted quantitation analysis of small molecules. The main areas of analysis are in the quantification of Polyphenols relating to dietary consumption and human health and the quantification of Mycotoxins in foods and crops, in particular, the detoxification of Deoxynivalenol. The LCMSMS facility now has four mass spectrometers, with access to an ion trap to support work in these areas of research.
Other Areas of interest include:
- Vitamin D3
- Methylamines
- Anthocyanins
- Nicotinamides
- Carboxymethyl Lysines
- Antibiotics
Latest Publications
Hemp Seed-Based Foods and Processing By-Products Are Sustainable Rich Sources of Nutrients and Plant Metabolites Supporting Dietary Biodiversity, Health, and Nutritional Needs
Ramos-Sanchez, R., Hayward, N. J., Henderson, D., Duncan, G. J., Russell, W. R., Duncan, S. H., Neacsu, M.Foods, vol. 14, no. 5, 875Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3390/foods14050875
Segmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals
Britton, K., Czére, O., Gutierrez, E., Reynar, L. M., Laird, E., Duncan, G., de Roos, B.Scientific Reports, vol. 15, 3078Contributions to Journals: ArticlesPersimmon Fiber-Rich Ingredients Promote Anti-Inflammatory Responses and the Growth of Beneficial Anti-Inflammatory Firmicutes Species from the Human Colon
López-Bermudo, L., Moreno-Chamba, B., Salazar-Bermeo, J., Hayward, N. J., Morris, A., Duncan, G. J., Russell, W. R., Cárdenas, A., Ortega, ?., Escudero-López, B., Berná, G., Martí Bruña, N., Duncan, S. H., Neacsu, M., Martin, F.Nutrients, vol. 16, no. 15, 2518Contributions to Journals: ArticlesBuckwheat (Fagopyrum esculentum) Hulls Are a Rich Source of Fermentable Dietary Fibre and Bioactive Phytochemicals: International Journal of Molecular Sciences
Zhang, Z., Fan, S., Duncan, G. J., Morris, A., Henderson, D., Morrice, P., Russell, W. R., Duncan, S. H., Neacsu, M.International Journal of Molecular Sciences, vol. 24, no. 22, 16310Contributions to Journals: ArticlesHabitual consumption of high-fibre bread fortified with bean hulls increased plasma indole-3-propionic concentration and decreased putrescine and deoxycholic acid faecal concentrations in healthy volunteers
Sayegh, M., Ni, Q. Q., Ranawana, V., Raikos, V., Hayward, N. J., Hayes, H., Duncan, G., Cantlay, L., Farquharson, F., Solvang, M., Horgan, G., Louis, P., Russell, W., Clegg, M., Thies, F., Neacsu, M.British Journal of Nutrition, vol. 130, no. 9, pp. 1521-1536Contributions to Journals: Articles
Page 2 of 3 Results 26 to 50 of 62
Phytochemical profile of commercially available food plant powders: their potential role in healthier food reformulations
Neacsu, M., Vaughan, N., Raikos, V., Multari, S., Duncan, G. J., Duthie, G. G., Russell, W. R.Food Chemistry, vol. 179, pp. 159-169Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.foodchem.2015.01.128
- [ONLINE] View publication in Scopus
Erratum to Role of pathogen-derived cell wall carbohydrates and prostaglandin E2 in immune response and suppression of fish immunity by the oomycete Saprolegnia parasitica
Belmonte, R., Wang, T., Duncan, G. J., Skaar, I., Mélida, H., Bulone, V., van West, P., Secombes, C. J., Appleton, J. (ed.)Infection and Immunity, vol. 83, no. 1, pp. 454Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/IAI.02821-14
- [ONLINE] View publication in Scopus
Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice
Duthie, S. J., Beattie, J. H., Gordon, M., Pirie, L. P., Nicol, F., Reid, M. D., Duncan, G. J., Cantlay, L., Horgan, G., McNeil, C. J.Genes & Nutrition, vol. 10, no. 1, 446Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s12263-014-0446-y
- [ONLINE] Pubmedcentral link to open access version
Role of Pathogen-Derived Cell Wall Carbohydrates and Prostaglandin E2 in Immune Response and Suppression of Fish Immunity by the Oomycete Saprolegnia parasitica
Belmonte, R., Wang, T., Duncan, G. J., Skaar, I., Mélida, H., Bulone, V., van West, P., Secombes, C. J.Infection and Immunity, vol. 82, no. 11, pp. 4518-4529Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/IAI.02196-14
Annual variation of dietary deoxynivalenol exposure during years of different Fusarium prevalence: a pilot biomonitoring study
Gratz, S. W., Richardson, A. J., Duncan, G., Holtrop, G.Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, vol. 31, no. 9, pp. 1579-1585Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1080/19440049.2014.937772
Bound phytophenols from ready-to-eat cereals: comparison with other plant-based foods
Neacsu, M., McMonagle, J., Fletcher, R. J., Scobbie, L., Duncan, G. J., Cantlay, L., de Roos, B., Duthie, G. G., Russell, W. R.Food Chemistry, vol. 141, no. 3, pp. 2880-2886Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.foodchem.2013.05.023
Microbial metabolism and intestinal absorption of the mycotoxin deoxynivalenol and its metabolites in humans
Gratz, S., Duncan, G., Richardson, A. J.Annals of Nutrition & Metabolism, vol. 63, no. Suppl 1, pp. 1806Contributions to Journals: AbstractsA methyl-deficient diet fed to rats during the pre- and peri-conception periods of development modifies the hepatic proteome in the adult offspring
Maloney, C. A., Hay, S. M., Reid, M. D., Duncan, G., Nicol, F., Sinclair, K. D., Rees, W. D.Genes & Nutrition, vol. 8, no. 2, pp. 181-190Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s12263-012-0314-6
Human fecal microbiota metabolize deoxynivalenol and deoxynivalenol-3-glucoside and may be responsible for urinary de-epoxy deoxynivalenol
Gratz, S. W., Duncan, G., Richardson, A. J.Applied and Environmental Microbiology, vol. 79, no. 6, pp. 1821-1825Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1128/AEM.02987-12
Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of protein
Russell, W. R., Duncan, S. H., Scobbie, L., Duncan, G., Cantlay, L., Calder, A. G., Anderson, S. E., Flint, H. J.Molecular Nutrition & Food Research, vol. 57, no. 3, pp. 523-535Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/mnfr.201200594
Inter-organ proteomic analysis reveals insights into the molecular mechanisms underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in ob/ob mice
Rungapamestry, V., McMonagle, J., Reynolds, C., Rucklidge, G., Reid, M., Duncan, G., Ross, K., Horgan, G., Toomey, S., Moloney, A. P., de Roos, B., Roche, H. M.Proteomics, vol. 12, no. 3, pp. 461-476Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/pmic.201100312
Anti-platelet effects of olive oil extract: in vitro functional and proteomic studies
de Roos, B., Zhang, X., Rodriguez Gutierrez, G., Wood, S., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Cantlay, L. L., Duthie, G. G., O'Kennedy, N.European Journal of Nutrition, vol. 50, no. 7, pp. 553-562Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00394-010-0162-3
High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health
Russell, W. R., Gratz, S. W., Duncan, S. H., Holtrop, G., Ince, J., Scobbie, L., Duncan, G., Johnstone, A. M., Lobley, G. E., Wallace, R. J., Duthie, G. G., Flint, H. J.The American Journal of Clinical Nutrition, vol. 93, no. 5, pp. 1062-1072Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3945/ajcn.110.002188
Impact of Obesity and Leptin on Protein Expression Profiles in Mouse Colon
Padidar, S., Farquharson, A. J., Williams, L. M., Hoggard, N., Reid, M. D., Duncan, G. J., Drew, J. E.Digestive Diseases and Sciences, vol. 56, no. 4, pp. 1028-1036Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s10620-010-1394-z
Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation
Duthie, S. J., Horgan, G., De Roos, B., Rucklidge, G., Reid, M., Duncan, G., Pirie, L., Basten, G. P., Powers, H. J.Journal of Proteome Research, vol. 9, no. 4, pp. 1941-1950Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1021/pr901103n
Intervention with fish oil, but not with docosahexaenoic acid, results in lower levels of hepatic soluble epoxide hydrolase with time in apoE knockout mice
Mavrommatis, Y., Ross, K., Rucklidge, G., Reid, M., Duncan, G. J., Gordon, M. J., Thies, F., Sneddon, A. A., De Roos, B.British Journal of Nutrition, vol. 103, no. 1, pp. 16-24Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0007114509991450
Maternal diets deficient in folic acid and related methyl donors modify mechanisms associated with lipid metabolism in the fetal liver of the rat
McNeil, C. J., Hay, S. M., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Rees, W. D.British Journal of Nutrition, vol. 102, no. 10, pp. 1445-1452Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0007114509990389
Balancing Inflammatory, Lipid, and Xenobiotic Signaling Pathways by VSL#3, a Biotherapeutic Agent, in the Treatment of Inflammatory Bowel Disease
Reiff, C., Delday, M., Rucklidge, G., Reid, M., Duncan, G., Wohlgemuth, S., Hoermannsperger, G., Loh, G., Blaut, M., Collie-Duguid, E., Haller, D., Kelly, D.Inflammatory Bowel Diseases, vol. 15, no. 11, pp. 1721-1736Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/ibd.20999
Gene and protein expression profiles in the foetal liver of the pregnant rat fed a low protein diet
McNeil, C. J., Hay, S. M., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Rees, W. D.Genes & Nutrition, vol. 4, no. 3, pp. 189-194Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s12263-009-0125-6
Phenolic acid content of fruits commonly consumed and locally produced in Scotland
Russell, W. R., Labat, A., Scobbie, L., Duncan, G. J., Duthie, G. G.Food Chemistry, vol. 115, no. 1, pp. 100-104Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.foodchem.2008.11.086
Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet
de Roos, B., Rungapamestry, V., Ross, K., Rucklidge, G., Reid, M., Duncan, G., Horgan, G., Toomey, S., Browne, J., Loscher, C. E., Mills, K. H. G., Roche, H. M.Proteomics, vol. 9, no. 12, pp. 3244-3256Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/pmic.200800761
The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses
Duthie, S. J., Mavrommatis, Y., Rucklidge, G., Reid, M., Duncan, G., Moyer, M. P., Pirie, L. P., Bestwick, C. S.Journal of Proteome Research, vol. 7, no. 8, pp. 3254-3266Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1021/pr700751y
Aorta protein networks in marginal and acute zinc deficiency
Beattie, J. H., Gordon, M. J., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Horgan, G. W., Cho, Y., Kwun, I.Proteomics, vol. 8, no. 10, pp. 2126-2135Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/pmic.200700784
Identification of potential serum biomarkers of inflammation and lipid modulation that are altered by fish oil supplementation in healthy volunteers
De Roos, B., Geelen, A., Ross, K., Rucklidge, G., Reid, M., Duncan, G., Caslake, M., Horgan, G., Brouwer, I. A.Proteomics, vol. 8, no. 10, pp. 1965-1974Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/pmic.200700457
Disruption of lipid metabolism in the liver of the pregnant rat fed folate-deficient and methyl donor-deficient diets
McNeil, C. J., Hay, S., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Maloney, C. A., Rees, W.British Journal of Nutrition, vol. 99, no. 2, pp. 262-271Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0007114507798999