Medicine & Therapeutics

Credit Points

15

Course Coordinator

Prof. Gay M. Hawksworth

Pre-requisites

A degree or equivalent in Medicine, Pharmacy or a relevant science subject.

Overview

Lectures, tutorials and practical classes. Topics - absorption, distribution, metabolism and excretion of drugs. Human drug metabolism - cytochrome P450. Induction/inhibition of cytochrome P450. Identification of cytochrome P450 at an early stage in drug discovery. Pharmacogenetics of human drug metabolism - implication for drug safety in clinical practice. Mechanisms of drug induced toxiity: reactive metabolites; glutathoine conjugate-mediated toxicity; cytoprotective mechanisms; agents conferring protection against drug toxicity - clinical applications; mechanisms of cell death; apoptosis and necrosis. Target organ toxicity. Toxicology of specified organ systems. Clinical biochemistry of drug toxicity. Pathology of drug toxicity. Haematological indices of drug toxicity.

Structure

2 x 1 hour lectures per week.
1 x 1 hour visit to a clinical department in the ARI during the module.
2 x lab practicals during weeks 1-2.

Assessment

1 written exam paper (75%)
3 assignments for continuous assessment (25%)

Credit Points

10

Course Coordinator

Dr James McLay

Pre-requisites

A degree or equivalent at the prescribed standard in Medicine, Pharmacy or a relevant science subject.

Overview

Lectures, seminars, tutorial and practical classes. Topics: - the clinical aspects of some of the commonly used group of drugs: their chemistry, pharmacology, medical use, absorption, distrubution, metabolism and excretion. Adverse drug actions and drug-drug interactions. Pharmacy aspects of safe prescribing and delivery of drugs: formularies, drug delivery systems and patient compliance.

Structure

1-2 1 1/2 hour lectures per week.
4 tutorials throughout the module.

Assessment

1 written exam (80%)
2 assignments for continuous assessment (20%)

Credit Points

5

Course Coordinator

Dr H M Wallace

Pre-requisites

A degree or equivalent qualification, at the prescibed standard in Medicine, Pharmacy or relevant Science

Overview

Lectures, seminars and workshops. Basic laboratory techniques, library facilities and presentation skills

Structure

3 x one hour lectures and 1 x one hour tutorial per week

Assessment

1 x 2 hour examination (60%) and continuous assessment (40%)

Credit Points

50

Course Coordinator

Dr Lindsey Masson

Pre-requisites

The course is restricted to students on the MSc Human Nutrition and Metabolism or PG Diploma in Human Nutrition programmes. A second class honours degree or equivalent in biological sciences such as biochemistry, physiology, nutrition or medicine

Notes

Overview

Lectures, seminars and practical classes on dietary assessment, macronutrients, energy balance and metabolism, micronutrients, nutritional status and body composition, nutrition throughout the life cycle, and diet and disease

Structure

5 three hour seminars or 10 one hour lectures per week: laboratory assignments to be arranged.

Assessment

Two 2 hour examininations (70%) and continuous assessment (30%)

Credit Points

20

Course Coordinator

Dr Heather M Wallace

Pre-requisites

A degree or equivalent qualification in Medicine, Pharmacy or relevant Science subject.

Overview

Lectures, seminars, tutorials and practical classes. Intracellular signaling, immunology, immunopharmacology, molecular carcinogenesis, chemotherapy and ethics.

Structure

2 x 1 hour lectures per week.
1 tutorial or seminar per week.
1 lab practical throughout the course.

Assessment

1 written examination paper (80%).
2 assignments for continuous assessment (20%)

Credit Points

0

Course Coordinator

Dr Heather Wallace

Pre-requisites

N/A

Overview

Compulsory course for students taking the Drug Development and Drug Development with Bio-business degree programmes.

Structure

Assessment

Credit Points

30

Course Coordinator

Dr Lindsey Masson

Pre-requisites

The course is restricted to students on the MSc Human Nutrition and Metabolism or PG Diploma in Human Nutrition programmes. The Human Nutrition core course or equivalent course from another institution is a pre-requisite for this course.

Co-requisites

MT5007

Overview

Lectures, seminars and practical classes on epidemiology and study design, laboratory methods, gene-nutrient interactions, tracer methodology and clinical nutrition.

Structure

5 three hour seminars or 10 one hour lectures per week; laboratory assignments and clinical attachments to be arranged.

Assessment

Two 2 hour examinations (70%) and continuous assessment (30%)

Credit Points

5

Course Coordinator

Dr MJ MacLeod

Pre-requisites

A degree or equivalent qualification, at the prescribed standard in Medicine, Pharmacy or a relevant Science subject (eg. Biochemistry, Biology or Pharmacy)

Co-requisites

None

Overview

The 1 week course will comprise lectures, tutorials and seminars. The curriculum will provide an in-depth look at pharmacovigilance using examples from both first and third world countries and will include detection of adverse drug reactions; causality assessment; prevention of adverse drug reactions including correct prescribing, prevention of drug errors and promotion of rational drug use; and communication of risk-benefit information to the general public.

Structure

5 x 1 hour lectures
5 tutorials/seminars

Assessment

1 assignment for continuous assessment (100%)

Credit Points

20

Course Coordinator

Dr James McLay

Pre-requisites

A degree or equivalent qualification at the prescribed standard in Medicine, Pharmacy or a relevant Science subject.

Overview

Impact or particular disease states with reference to the pathophysiology, epidemiology, economic cost and current drugs available. Rationale for further drug development and clinical trails. End point measurements. Drug trial design. Critical analysis of 'key' publications on the treatment of disease. Clinical guidelines. Selecting a limited list of medicines. Pharmacovigilance. Ethics. Development of a new medicinal compound from pharmacology to pharmaceutical product.

Structure

2 x 1 1/2 hour lectures per week.
1 x 1 hour lecture per week.
1 x 3 hour visit to a clinical department in the ARI per week.
2 seminars: one day long and 1.5 days long, throughout weeks 15-22.
4 tutorials throughout week 15-22.

Assessment

2 written exam paper (60%)
3 assignments for continuous assessment (40%)

Credit Points

10

Course Coordinator

Prof Gay M. Hawksworth

Pre-requisites

A degree or equivalent qualification, at the prescribed standard in Medicine, Pharmacy or a relevant Science subject.

Overview

Lectures, tutorials and a practical class. Topics: - logarithmic functions, first order & zero order kinetics, determination of clearance, elimination rate constant, half life, volume of distribution, renal clearance, one & two compartment model IV bolus, one compartment model oral administration, multiple dosing, intravenous infusuions model independent analysis, assessment of absorption rate, linear/non linear kinetics, bioavailability, bioequivalence, examples of trials, convolution & deconvolution, in-vitro/in-vivo correlations, pharmacokinetics/pharmacodynamics, therapeutic windows, calculation of pharmacokinetic parameters, pharmacokinetics as a tool in drug development, dosage regimes, idiosyncratic drug reactions, therapeutics drug monitoring, toxic drug screening.

Structure

2 x 1 hour lectures per week.
2 tutuorials during the module.
1 lab practical during the module.

Assessment

1 written exam (80%)
1 assignment for continuous assessment (20%)

Credit Points

25

Course Coordinator

Dr Heather M Wallace

Pre-requisites

Attainment at the appropriate level in the taught courses of the Diploma/MSc Clinical Pharmacology common programme.

Co-requisites

Restricted to students on the Diploma in Clinical Pharmacology Programme.

Overview

Each dissertation is distinct and dependent on the student's interests and the work being pursued by research groups within the department at the time. All proposed dissertations are reviewed by the course coordinators and committee before being offered to the students.

Structure

No formal teaching during the research period. Departmental seminar - 1 hour per week.

Assessment

Thesis (80%)
Defence of Thesis at Viva (20%)

Credit Points

Course Coordinator

Dr Heather M Wallace

Pre-requisites

A Pass in each of the taught courses of the MSc Clinical Pharmacology programme.

Notes

Overview

Each project is distinct and is dependent on the work being pursued by research groups within the department at the time. All projects are reviewed by the course coordinators and committee before it is offered to the students.

Structure

No formal teaching during the research period. Departmental seminar - 1 hour per week.

Assessment

Thesis (60%)
Oral Presentation of Work (20%)
Defence of Thesis at Viva (20%)

Credit Points

90

Course Coordinator

Dr Lindsey Masson

Pre-requisites

This course is restricted to students on the MSc Human Nutrition & Metabolism programme. The Human Nutrition core course and the Human Nutrition and Metabolism taught course are pre-requisites

Overview

Full-time supervised research project on a topic related to human nutrition and metabolism in laboratory or clinical setting

Structure

Full-time research work as dictated by the specific project

Assessment

Thesis (University internal examiner 25%
Thesis (Rowett internal examiner) 25%
Thesis (external examiner) 25%
Oral presentation of project results 25%

Credit Points

30

Course Coordinator

Dr Lindey Masson

Pre-requisites

This course is restricted to students on the PG Human Nutrition and Metabolism programme. The Human Nutrition core course and the Human Nutrition and Metabolism taught course are pre-requisites.

Notes

Overview

Full-time literature review on a topic related to human nutrition chosen by the student in consultation with an appointed supervisor

Structure

Full-time research work as dictated by the specific project.

Assessment

Dissertation 100%

Credit Points

20

Course Coordinator

Dr Heather Wallace

Pre-requisites

A pass in each of the taught courses in the MSc degree programmes for Drug Development and Drug Development and Bio-Business

Overview

Dissertation for candidates taking Postgraduate Diploma in Drug Development and Drug Development with Bio-Business

Structure

Assessment

Credit Points

Course Coordinator

Dr Heather Wallace

Pre-requisites

N/A

Notes

Overview

Research Project for Drug Development and Drug Development and Bio-Business MSc

Structure

Assessment