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MT5518: PHARMACOKINETICS (2023-2024)

Last modified: 23 Jul 2024 10:43


Course Overview

Pharmacokinetics describe “what the body does to a drug” and thus is a central feature of applied pharmacology. The course will develop an understanding of the role that pharmacokinetics play in all aspects of drug administration, distribution, metabolism and excretion and how these effects can be modelled and predicted graphically and mathematically. Such modelling is a fundament of therapeutic regimen design, drug development, clinical pharmacology and drug safety and will be considered within all of these contexts providing a broad and relevant appreciation of the importance of pharmacokinetics to the pharmacologist

Course Details

Study Type Postgraduate Level 5
Term Second Term Credit Points 15 credits (7.5 ECTS credits)
Campus Aberdeen Sustained Study No
Co-ordinators
  • Professor Steven Tucker

What courses & programmes must have been taken before this course?

  • Any Postgraduate Programme (Studied)
  • One of MSc Clinical Pharmacology (Studied) or MSc Drug Discovery and Development (Studied) or MSc Bio-Business and Medical Sciences (Studied)

What other courses must be taken with this course?

None.

What courses cannot be taken with this course?

None.

Are there a limited number of places available?

No

Course Description

The course combines lecture-based learning, with tutorials and laboratory practicals, aimed to enhance understanding of pharmacokinetic principles by combining theory, practice and application.

Lectures will focus on the pharmacokinetic considerations of single intravenous (IV) or single oral administration, and also multiple IV and oral administration with contextualised tutorials integrated to reinforce and demonstrate key lecture principles. There will be additional tutorials using online support tools, as an added means of teaching support.

The course will also consider the importance of pharmacokinetics from a clinical perspective and also a drug development/design angle to deliver an appreciation of the professional use of these skills.

A laboratory project will provide a further dimension to explore pharmacokinetics where a model system will be used to simulate single IV and single oral administration of a drug, with generated data then compared by applying the skills developed throughout the course.


Contact Teaching Time

Information on contact teaching time is available from the course guide.

Teaching Breakdown

More Information about Week Numbers


Details, including assessments, may be subject to change until 30 August 2024 for 1st term courses and 20 December 2024 for 2nd term courses.

Summative Assessments

Report: Individual

Assessment Type Summative Weighting 40
Assessment Weeks 35 Feedback Weeks 37

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Learning Outcomes
Knowledge LevelThinking SkillOutcome
ProceduralEvaluatebe able to integrate pharmacokinetic variables with their clinical relevance to summarise key aspects of a drug administration regimen

Case study – using provided data to inform clinical decisions and discuss drug design

Assessment Type Summative Weighting 30
Assessment Weeks 31 Feedback Weeks 33

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Learning Outcomes
Knowledge LevelThinking SkillOutcome
ProceduralEvaluatebe able to critically appraise the pharmacokinetic profile of a new drug candidate making recommendations on how the drug is administered in man

Calculation exercise – demonstrating ability to calculate pharmacokinetic parameters and explain mea

Assessment Type Summative Weighting 30
Assessment Weeks 28 Feedback Weeks 30

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Learning Outcomes
Knowledge LevelThinking SkillOutcome
ConceptualApplybe able to apply pharmacokinetic principles to accurately solve calculation problems relating to drugs and their administration to humans

Formative Assessment

There are no assessments for this course.

Course Learning Outcomes

Knowledge LevelThinking SkillOutcome
ConceptualApplybe able to apply pharmacokinetic principles to accurately solve calculation problems relating to drugs and their administration to humans
ProceduralEvaluatebe able to integrate pharmacokinetic variables with their clinical relevance to summarise key aspects of a drug administration regimen
ProceduralEvaluatebe able to critically appraise the pharmacokinetic profile of a new drug candidate making recommendations on how the drug is administered in man

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