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Postgraduate Medicine and Therapeutics 2017-2018

MT5003: DRUG METABOLISM & TOXICOLOGY

15 credits

Level 5

First Term

This course provides advanced level drug metabolism and includes the importance of drug transporters in the drug discovery process, dealing with molecular toxicology and pharmacology at an advanced level. Mechanisms of drug and oxidative stress and immunopharmacology are described. External experts are invited to provide their unique expertise on a range of topics which can include toxicopathology, immunotoxicology, risk assessment and an industrial perspective on the drug discovery process.

MT5010: BASIC SKILLS - INDUCTION

0 credits

Level 5

First Term

This course is designed to provide or revise the basic skills you will require for your MSc. The course will revise basic laboratory skills and techniques and advance these to a level required to undertake graduate practical classes and projects by developing hands-on experience, competence and confidence in key laboratory skills. An expert from the library will explain the use and facilities of the library and the basics of database searching to enhance research skills and project validation.

MT5017: RESEARCH AND SCIENTIFIC WRITING

30 credits

Level 5

First Term

This course is designed for Academic Foundation Program (AFP) doctors, although it is also open to any doctor aspiring to clinical academia. You will apply the generic research skills that you learned within other modules to a clinical context to further develop your skills towards a career in academic medicine. This course will facilitate your understanding of the important strategies and approaches that will underpin your future research career.

MT5020: EXTENDED RESEARCH PROJECT

60 credits

Level 5

First Term

MT5024: MOLECULAR PHARMACOLOGY

15 credits

Level 5

First Term

This course will cover a wide range of topics and will include revision of receptor theory and intra- and inter- cellular communication.  Cancer will be used a s model disease and the molecular basis of cancer, how it is treated, clinical issues, drug resistance and chemotherapy and prevention

MT5026: RESEARCH SKILLS (PGCERT MEDICAL RESEARCH SKILLS)

30 credits

Level 5

First Term

This course is designed for Academic Foundation Program (AFP) doctors, although it is also open to any doctor aspiring to clinical academia. You will be provided with training in generic research skills within a clinical context to allow you to develop your skills towards a career in academic medicine. The teaching combines interactive and practical approaches which will facilitate your understanding of the important strategies and approaches that will underpin your future research career.

MT5027: THERAPEUTICS

15 credits

Level 5

First Term

This course will describe and review the use of medicinal compounds in man together with methods to assess and describe efficacy and toxicity. A number of exemplar disease areas and at risk populations will be selected and the drugs used to treat these conditions and populations discussed and explained. The importance of understand drug mechanisms of action and associated risk as well as benefit will be emphasised in a clinical setting. The course will consider both drugs in current use and those in development.

MT5513: RESEARCH PROJECT 1

60 credits

Level 5

Second Term

The first research project of the MRes programme involves working on an independent research project for 12 weeks prior to completion of a dissertation. It involves utilisation of much of the skills developed throughout the previous semester, and is selected based on student interests and preferences.

MT5515: BASIC RESEARCH METHODS

15 credits

Level 5

Second Term

This course reviews a range of methodologies that are currently used in basic research.  Experts in the various techniques describe the methodology and showcase the equipment.

MT5518: PHARMACOKINETICS

15 credits

Level 5

Second Term

Pharmacokinetics describe “what the body does to a drug” and thus is a central feature of applied pharmacology. The course will develop an understanding of the role that pharmacokinetics play in all aspects of drug administration, distribution, metabolism and excretion and how these effects can be modelled and predicted graphically and mathematically. Such modelling is a fundament of therapeutic regimen design, drug development, clinical pharmacology and drug safety and will be considered within all of these contexts providing a broad and relevant appreciation of the importance of pharmacokinetics to the pharmacologist

MT5519: COMMUNICATING CLINICAL SAFETY AND REGULATION WITH INDUSTRY AND THE PUBLIC

15 credits

Level 5

Second Term

The will comprise lectures, tutorials and seminars. The curriculum will provide an in-depth look at pharmacovigilance, communication with regulators and the public using examples from both first and third world countries and will include detection of adverse drug reactions; causality assessment; prevention of adverse drug reactions including correct prescribing, prevention of drug errors and promotion of rational drug use; and communication of risk-benefit information to the general public. It will also include an introduction to the commercialisation of scientific ideas in the form of Bio-Business covering the pharma industry, spin out companies, IPR and finance.

MT5520: DRUG DEVELOPMENT TO EVIDENCE BASED MEDICINE

15 credits

Level 5

Second Term

This course will provide you with an introduction to evidence-based medicine. It will also include a description of the elements of pharmaceutical research as well as of the drug development process.

MT5811: RESEARCH PROJECT MANAGEMENT

30 credits

Level 5

Second Term

Gaining direct experience of the processes involved in managing the early stages of a specialist research project in nutrition this course focuses on an initial literature review of a research topic, preparing a research protocol, as well as developing good professional practice when undertaking a scientific research project.

MT5903: RESEARCH PROJECT 2

60 credits

Level 5

Second Term

The research project is the climax of the MSc programme and involves working on an independent research project for 12 weeks prior to completion of a dissertation. It involves utilisation of much of the skills developed throughout the previous 2 semesters, and is selected based on student interests and preferences.

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