Last modified: 20 Hours, 53 Minutes ago
This course will cover the principles of toxicology including molecular toxicology and target organ toxicity, mechanisms of cell death, molecular carcinogenesis and safety evaluation of carcinogens, adverse outcome pathways (AOPs) and new alternative methods (NAMs). These elements will be taught around the processes involved in drug discovery and development and will include advanced learning on drug metabolism and drug transporters. The course will also provide the principles and practice of risk assessment and regulatory toxicology. External experts are invited to provide their unique expertise on a range of topics, which include regulatory aspects as well as an industrial perspective on the drug discovery process.
| Study Type | Postgraduate | Level | 5 |
|---|---|---|---|
| Term | First Term | Credit Points | 15 credits (7.5 ECTS credits) |
| Campus | Aberdeen | Sustained Study | No |
| Co-ordinators |
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Topics - Principles of toxicology; target organ toxicity and oxidative stress; molecular toxicology; mechanisms of cell death; molecular and chemical carcinogenesis; use of biomarkers; safety evaluation of carcinogens; drug metabolism and transporters; Risk Assessment; regulatory toxicology.
Information on contact teaching time is available from the course guide.
| Assessment Type | Summative | Weighting | 50 | |
|---|---|---|---|---|
| Assessment Weeks | 15,17 | Feedback Weeks | 17,19 | |
| Feedback |
Portfolio of Toxicology Scenarios Word Count: 2500-3000 |
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| Knowledge Level | Thinking Skill | Outcome |
|---|---|---|
| Conceptual | Apply | Apply advanced aspects of molecular pharmacology, drug metabolism and drug transport to toxicology issues |
| Conceptual | Understand | Recognise the concepts supporting industrial drug research and development |
| Procedural | Apply | Understand and apply the principles of toxicity testing, risk assessment and regulatory toxicology |
| Procedural | Evaluate | Evaluate issues in toxicology using basic toxicological information |
| Procedural | Understand | Understand advanced concepts in toxicology, including AOPs, NAMs, oxidative stress, organ specific toxicity and the types and use of biomarkers |
| Assessment Type | Summative | Weighting | 25 | |
|---|---|---|---|---|
| Assessment Weeks | Feedback Weeks | |||
| Feedback |
Word Count: 850 |
|||
| Knowledge Level | Thinking Skill | Outcome |
|---|---|---|
| Conceptual | Apply | Apply advanced aspects of molecular pharmacology, drug metabolism and drug transport to toxicology issues |
| Procedural | Evaluate | Evaluate issues in toxicology using basic toxicological information |
| Procedural | Understand | Understand advanced concepts in toxicology, including AOPs, NAMs, oxidative stress, organ specific toxicity and the types and use of biomarkers |
| Assessment Type | Summative | Weighting | 25 | |
|---|---|---|---|---|
| Assessment Weeks | Feedback Weeks | |||
| Feedback |
Duration: 15 minutes |
|||
| Knowledge Level | Thinking Skill | Outcome |
|---|---|---|
| Conceptual | Apply | Apply advanced aspects of molecular pharmacology, drug metabolism and drug transport to toxicology issues |
| Conceptual | Understand | Recognise the concepts supporting industrial drug research and development |
| Procedural | Evaluate | Evaluate issues in toxicology using basic toxicological information |
There are no assessments for this course.
| Knowledge Level | Thinking Skill | Outcome |
|---|---|---|
| Procedural | Evaluate | Evaluate issues in toxicology using basic toxicological information |
| Procedural | Apply | Understand and apply the principles of toxicity testing, risk assessment and regulatory toxicology |
| Conceptual | Apply | Apply advanced aspects of molecular pharmacology, drug metabolism and drug transport to toxicology issues |
| Conceptual | Understand | Recognise the concepts supporting industrial drug research and development |
| Procedural | Understand | Understand advanced concepts in toxicology, including AOPs, NAMs, oxidative stress, organ specific toxicity and the types and use of biomarkers |
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