BI20M3: MOLECULAR BIOLOGY OF THE GENE (2024-2025)

The course is divided into 4 main modules as follows; 1. Nucleic Acids: this module will provide an overview of nucleic acid biochemistry with emphasis on the dynamic structure of DNA and the way in which it is replicated and packaged into chromosomes. The basic principles of modern recombinant DNA technologies will also be introduced. 2. Gene regulation: one of the most important questions within modern biology centres on how one- dimensional information held within the DNA is turned into healthy living 3-dimensional organisms that are able to interact with their environments. This module will describe how this information is decoded by transcription and translation to form proteins and how organisms control these processes to ensure that the correct proteins are produced in the correct cells at the correct times and in the correct amounts. 3. Peptides and proteins: this module will provide a comprehensive introduction to protein biochemistry, building on the basic chemistry of amino acids and peptides. The properties of proteins will be described, using a number of specific examples. The final lectures in the module will consider the methods used to study proteins. These provide the information that underlies our current understanding of protein structure and function. 4. Genetic disease: this module will explain how genomes can be compromised by mutation and chromosomal rearrangements leading to disorders such as Downs syndrome, cystic fibrosis, fragile-X syndrome and cancer.

Information on contact teaching time is available from the course guide.

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There are no assessments for this course.