Senior Lecturer
- About
-
- Email Address
- w.huang@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437290
- Office Address
Room 5.26
Institute of Medical Sciences
University of Aberdeen
Foresterhill, Aberdeen
Scotland, AB25 2ZD.- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Current post:
Senior Lecturer
Institute of Medical Sciences
University of AberdeenPrevious posts:
Senior Research Scientist
Imperial College LondonInternal Memberships
Dr Huang involves in the following Administration duties:
• Provide scientific and career advice to BSc Honours, Master and PhD students
• Provide pastoral care to personal tutees at UoA
• Act as academic advisors/examiners for PhD students of other academic staff• Member of the Dignity at Work and Study Working Group of UoA
- Research
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Research Overview
My laboratory aims to develop novel approaches to improve function recovery after spinal cord injury, and we are pursuing the following two research areas:
A Combinatorial Approach For Spinal Cord Repair
Based on our previous experience using novel biomaterials for peripheral nerve repair, my group is focusing on the development of a biomaterial-based combinatorial approach to promote axon regeneration and function recovery after spinal cord injury using relevant in vitro, ex vivo and animal models. In collaboration with colleagues here at Aberdeen and elsewhere, we are developing novel combinatorial strategies including the use of suitable novel biomaterials, novel growth-promoting biomolecules, and electric stimulation for spinal cord repair.Central Neuropathic Pain After Spinal Cord Injury
My group has a strong interest in the role of neuroinflammation in the development and maintenance of central neuropathic pain following spinal cord injury. We aim to develop novel strategies to target this neuroinflammation in order to prevent and/or treat this common complication that significantly impacts on the quality of life of millions spinal injured patients.Research Specialisms
- Neuroscience
- Tissue Engineering and Regenerative Medicine
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
Collaborations
In Aberdeen:
- Dr Huang is part of the Aberdeen Spinal Injury Research Team and actively collaborates with other Team members to develop novel strategies for spinal cord repair.
Outside Aberdeen: Dr Huang actively collaborate with national and international leading experts.
Industrial collaboration:
- Oxford Biomaterials Ltd., Oxford, England
- Biogelx Ltd., Scotland
- Cell Guidance Systems, Cambridge
Supervision
Current PhD students:
Hongming Ma (1st year; Principal supervisor: Dr Wenlong Huang; second supervisor: Prof Colin McCaig)
Dominik Domanski (2nd year; principal supervisor: Dr Wenlong Huang; second supervisor: Dr Guy Dewick)
Abigail Dos Santos (2nd year; Principal supervisor: Dr Bewick, second supervisor: Dr Wenlong Huang)
William Macintosh-Smith (3rd year; Principal supervisor: Dr Wenlong Huang; second supervisor: Prof Colin McCaig)
Mindaugas Viskontas (3rd year; principal supervisor: Dr Wenlong Huang; second supervisor: Dr Derryck Shewan)
Past PhD students:
Yuting Wei (graduated 2021)
Anna Varone (graduated 2019)
Alba Guijarro-Belmar (gradudated 2019)
Marieta Georgieva (graduated 2018)
Funding and Grants
Current Research Income:
Research Grants (total £563K since 2017):
• Scottish Rugby Union/private donation, 2019-24
• Aberdeen University Development Trust, 2016-24
• BJA/RCoA PhD studentship, 2020-2024
• Medical Research Scotland, 2019-2024
• One Elphinstone PhD Scholarship, 2020-2023
• International PhD studentship, 2021-24Our research is kindly supported by:
Previous Grants:
• Institute of Medical Sciences PhD Studentship, 2014-19
• International Spinal Research Trust PhD Studentship, 2015-19
• Aberdeen University Development Trust PhD Studentship, 2014-18
• Aberdeen University Development Trust, 2016-19
• Tenovus Scotland, 2016-17
• RS McDonald Trust, 2014-17
• Scottish Rugby Union, Research Grant, 2013-16
• Development Trust, Equipment Grant, 2013-16
• Medical Research Scotland Vacation Scholarship, 06-08/2015
• Medical Research Scotland Vacation Scholarship, 06-08/2016
• Wellcome Trust Vacation Scholarship, 06-08/2016
• Aberdeen University Start-up, 2013-2016
• National Institute of Academic Anaesthesia, 2013-14
• Chelsea & Westminster NHS Trust; 2010-11
• Neurotex Ltd., 2008-9
• Wellcome Trust, International Travelling Research Fellowship, 2001-2 - Teaching
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Teaching Responsibilities
For the Institute of Medical Sciences:
PGT: MSc IMS Project Course: course coordinator
Level 2
• SM2001: Foundation Skills for Medical Sciences
• SM2501: Research Skills for Medical SciencesLevel 3
• SM3002: Frontiers of Medical Sciences: course coordinator
• SR3508: Clinical Exercise Physiology
• BM3804: Neuroscience Research Topics
• DB3804: Development of Organ SystemsLevel 4
• BM4004: Advanced Molecules, Membranes & Cells
• PY4302/AN4302: Developmental NeuroscienceFor the Medical School:
• Yr1: tutors on various topics
• Yr1: SSC "Brainstorming": theme leader
• Yr2: tutors on various topicsSupervision of BSc and postgraduate students:
• BSc Honours
• MSc/MRes students
• Principal supervisor of 4 PhD students - Publications
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Page 1 of 1 Results 1 to 22 of 22
The potential of gene therapies for spinal cord injury repair: a systematic review and meta-analysis of pre-clinical studies
Neural Regeneration Research, vol. 18, no. 2, pp. 299-305Contributions to Journals: Review articlesEffectiveness of biomaterial-based combination strategies for spinal cord repair – a systematic review and meta-analysis of preclinical literature
Spinal Cord, vol. 60, no. 12, pp. 1041-1049Contributions to Journals: Review articlesThe therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3′,5′-monophosphate (Epac) for central nervous system trauma
Neural Regeneration Research, vol. 16, no. 3, pp. 460-469Contributions to Journals: Review articlesThe Therapeutic Potential of the Stem Cell Secretome for Spinal Cord Repair: A Systematic Review and Meta-Analysis
OBM Neurobiology, vol. 4, no. 4Contributions to Journals: Review articlesFatty acid suppression of glial activation prevents central neuropathic pain after spinal cord injury
Pain, vol. 160, no. 12, pp. 2724-2742Contributions to Journals: Articles- [ONLINE] http://links.lww.com/PAIN/A854
- [ONLINE] DOI: https://doi.org/10.1097/j.pain.0000000000001670
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14798/1/PAIN_D_19_00177_R1.pdf
- [ONLINE] http://Insights.ovid.com/crossref?an=00006396-900000000-98626
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
General Principles of Preclinical Study Design
Handbook of Experimental Pharmacology. Springer, pp. 1-15, 15 pagesChapters in Books, Reports and Conference Proceedings: Chapters- [ONLINE] DOI: https://doi.org/10.1007/164_2019_277
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13312/1/2019_Chapter_.pdf
Epac2 Elevation Reverses Inhibition by Chondroitin Sulfate Proteoglycans In Vitro and Transforms Postlesion Inhibitory Environment to Promote Axonal Outgrowth in an Ex Vivo Model of Spinal Cord Injury
Journal of Neuroscience, vol. 39, no. 42, pp. 8330-8346Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1523/JNEUROSCI.0374-19.2019
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13690/1/Guijarro_Belmar_atal_JNeurosci_Epac2_Elevation_VOR.pdf
- [ONLINE] http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.0374-19.2019
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
A refined rat primary neonatal microglial culture method that reduces time, cost and animal use
Journal of Neuroscience Methods, vol. 304, pp. 92-102Contributions to Journals: ArticlesSilkworm silk biomaterials for spinal cord repair: promise for combinatorial therapies
Neural Regeneration Research, vol. 13, no. 5, pp. 809-810Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.4103/1673-5374.232471
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/10502/1/NeuralRegenResArticle.pdf
The potential of Antheraea pernyi silk for spinal cord repair
Scientific Reports, vol. 7, pp. 1-10Contributions to Journals: ArticlesA rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy
Pain, vol. 158, no. 1, pp. 75-85Contributions to Journals: ArticlesCross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study
Pain, vol. 157, no. 10, pp. 2350-2365Contributions to Journals: ArticlesEnsuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations
Pain, vol. 157, no. 4, pp. 901-909Contributions to Journals: ArticlesExperimental design and reporting standards for improving the internal validity of pre-clinical studies in the field of pain: Consensus of the IMI-Europain consortium
Scandinavian Journal of Pain, vol. 7, pp. 58-70Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.sjpain.2015.01.006
Macrophage-sensory neuronal interaction in HIV-1 gp120-induced neurotoxicity
British Journal of Anaesthesia, vol. 114, no. 3, pp. 499-508Contributions to Journals: ArticlesHeterogeneous responses of dorsal root ganglion neurons in neuropathies induced by peripheral nerve trauma and the antiretroviral drug stavudine
European Journal of Pain, vol. 19, no. 2, pp. 236-245Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/ejp.541
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4216/1/ejp541.pdf
Short-term effect of acute and repeated urinary bladder inflammation on thigmotactic behaviour in the laboratory rat
F1000 Research, vol. 4, 109Contributions to Journals: ArticlesA characterization of white matter pathology following spinal cord compression injury in the rat
Neuroscience, vol. 260, pp. 227-239Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.neuroscience.2013.12.024
HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain
Pain, vol. 154, no. 9, pp. 1668-1679Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.pain.2013.05.021
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/4691/1/1_s2.0_S0304395913002479_main.pdf
- [ONLINE] View publication in Scopus
A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy
Pain, vol. 154, no. 4, pp. 560-575Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.pain.2012.12.023
- [ONLINE] View publication in Scopus
Transparency in the reporting of in vivo pre-clinical pain research: The relevance and implications of the ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines
Scandinavian Journal of Pain, vol. 4, no. 2, pp. 58-62Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.sjpain.2013.02.002
Improved outcome after spinal cord compression injury in mice treated with docosahexaenoic acid
Experimental Neurology, vol. 239, pp. 13-27Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.expneurol.2012.09.015